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The map label for this gene is yleA [C]

Identifier: 150401611

GI number: 150401611

Start: 1254528

End: 1255877

Strand: Direct

Name: yleA [C]

Synonym: Maeo_1188

Alternate gene names: 150401611

Gene position: 1254528-1255877 (Clockwise)

Preceding gene: 150401609

Following gene: 150401615

Centisome position: 79.93

GC content: 28.96

Gene sequence:

>1350_bases
ATGAATTTAAAAACATTAAAAATATTCATAGAAGGATATGGTTGCACACTTAACACAGCAGATACAAACATAATAAATAA
TTCTATAAAGAAATTTAAGAACTTTATTATTGTAAATAATTTAGATGATGCCGATATTGTGGTCATAAACACTTGTGTTG
TTAGGTTAGAAACAGAGCACAAAATGATTTCGCGTATAAATTATATTAAATCATTAAATAAATACATTGTTATAGCTGGC
TGTATGCCGAAGGCACTAAAAAAGAAAGCCGAGAAAATAAATCCAGATATATTAATAATGCCAAAAGAGGCACATCTTAT
AGGGGATATAATATATAATTATTTTAAAAATAATATAGGTAATGAAAATAATGCCGATAATAAAATAGAGGACAGTATGA
AATGTGGGGAGCTCCCTCATAATCAGGCTTCATCCAGTGGCAACTATAACGACATTGATAATAAACTAACCCAATTAAAA
CCAAATAATTTAATAATGCCATTACCTATATCGGAAGGATGCACTGGAAAATGCACATATTGTATCGTAAAAATAGCAAG
GGGTAGATTGGCCTCATATAATCCCGATAAAATAATAAATAAAGCAAAAGAATTTGTAGATAATGGAGTAAAACAGATGT
TAATTACTTCGCAGGATACGGCATGTTATGGATTTGATAAAAACACTACGCTACCAACATTATTAAATGAAATATGCCAA
ATTAAAGGAGATTTCAACATAAGAATAGGAATGATGCATGCTAAAAATGTCCCTATGATTATCGATGAATTGATAGACCG
TTATAAAGATGATAAAATTACAAAATTTTTCCACCTTCCAATCCAAAGTGGAGATGATGATGTTTTAAGGGCAATGAAAA
GAGAATATACTGTTGATGAATATATGGACATTGCAATGGAATTTAAACGAAAAATAAAGGATTTAAACTTTAACACTGAT
GTTATTGTGGGGTTCCCAACTGAAACAGAGGATAATTTTAATAATACAATAGAATTATTAAAAAAATTAAAGCCTGATGC
AATACATGGGGCAAAATATACTCAACGAAAAGGAACAGAGGCAGATAGATTAAAACAAGTAGATACCAAAATACGAAAGG
AGAGAATGAAGATATTGGATAAATTAAGAAAAGAATTTAGTCTGGAAAATCATGAGAAATATGTTGGAAAAATTATGCCT
TGTCTCATTGTTGGAAAAAATGAGGGTATAACTCACAACTGTAAAACTGTAAAATTTGAAAATTGTGAAGATGTTAAAAT
AGGGGAATTTAGAAAAATAAAAATAAAAGAGGCTTTAACATTTGGTTTATATGGGGAAATAATTAATTAA

Upstream 100 bases:

>100_bases
TTTACTGGCTTTCATAGTGTATTACCTCGATTATATAATATATAAATATATGTGTAGTTAAACAATAAATAACCAATATA
AAATAAACAATTGTGATATA

Downstream 100 bases:

>100_bases
AAAATTAAAAACAAAAGTAAGAAATTAAAAGTAAGAAATAGAATTGATTTGATATTATACTTATTTAAATATTTTATCTA
AATATTGGCTGTAATGAGCA

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MNLKTLKIFIEGYGCTLNTADTNIINNSIKKFKNFIIVNNLDDADIVVINTCVVRLETEHKMISRINYIKSLNKYIVIAG
CMPKALKKKAEKINPDILIMPKEAHLIGDIIYNYFKNNIGNENNADNKIEDSMKCGELPHNQASSSGNYNDIDNKLTQLK
PNNLIMPLPISEGCTGKCTYCIVKIARGRLASYNPDKIINKAKEFVDNGVKQMLITSQDTACYGFDKNTTLPTLLNEICQ
IKGDFNIRIGMMHAKNVPMIIDELIDRYKDDKITKFFHLPIQSGDDDVLRAMKREYTVDEYMDIAMEFKRKIKDLNFNTD
VIVGFPTETEDNFNNTIELLKKLKPDAIHGAKYTQRKGTEADRLKQVDTKIRKERMKILDKLRKEFSLENHEKYVGKIMP
CLIVGKNEGITHNCKTVKFENCEDVKIGEFRKIKIKEALTFGLYGEIIN

Sequences:

>Translated_449_residues
MNLKTLKIFIEGYGCTLNTADTNIINNSIKKFKNFIIVNNLDDADIVVINTCVVRLETEHKMISRINYIKSLNKYIVIAG
CMPKALKKKAEKINPDILIMPKEAHLIGDIIYNYFKNNIGNENNADNKIEDSMKCGELPHNQASSSGNYNDIDNKLTQLK
PNNLIMPLPISEGCTGKCTYCIVKIARGRLASYNPDKIINKAKEFVDNGVKQMLITSQDTACYGFDKNTTLPTLLNEICQ
IKGDFNIRIGMMHAKNVPMIIDELIDRYKDDKITKFFHLPIQSGDDDVLRAMKREYTVDEYMDIAMEFKRKIKDLNFNTD
VIVGFPTETEDNFNNTIELLKKLKPDAIHGAKYTQRKGTEADRLKQVDTKIRKERMKILDKLRKEFSLENHEKYVGKIMP
CLIVGKNEGITHNCKTVKFENCEDVKIGEFRKIKIKEALTFGLYGEIIN
>Mature_449_residues
MNLKTLKIFIEGYGCTLNTADTNIINNSIKKFKNFIIVNNLDDADIVVINTCVVRLETEHKMISRINYIKSLNKYIVIAG
CMPKALKKKAEKINPDILIMPKEAHLIGDIIYNYFKNNIGNENNADNKIEDSMKCGELPHNQASSSGNYNDIDNKLTQLK
PNNLIMPLPISEGCTGKCTYCIVKIARGRLASYNPDKIINKAKEFVDNGVKQMLITSQDTACYGFDKNTTLPTLLNEICQ
IKGDFNIRIGMMHAKNVPMIIDELIDRYKDDKITKFFHLPIQSGDDDVLRAMKREYTVDEYMDIAMEFKRKIKDLNFNTD
VIVGFPTETEDNFNNTIELLKKLKPDAIHGAKYTQRKGTEADRLKQVDTKIRKERMKILDKLRKEFSLENHEKYVGKIMP
CLIVGKNEGITHNCKTVKFENCEDVKIGEFRKIKIKEALTFGLYGEIIN

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=396, Percent_Identity=30.8080808080808, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI28872782, Length=436, Percent_Identity=25, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI28872784, Length=436, Percent_Identity=25, Blast_Score=136, Evalue=4e-32,
Organism=Escherichia coli, GI1786882, Length=468, Percent_Identity=24.5726495726496, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1787057, Length=459, Percent_Identity=24.6187363834423, Blast_Score=152, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71996771, Length=309, Percent_Identity=33.0097087378641, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17553146, Length=491, Percent_Identity=26.0692464358452, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI19922432, Length=451, Percent_Identity=26.6075388026608, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI21356207, Length=443, Percent_Identity=25.5079006772009, Blast_Score=142, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 51389; Mature: 51389

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKTLKIFIEGYGCTLNTADTNIINNSIKKFKNFIIVNNLDDADIVVINTCVVRLETEH
CCCEEEEEEEEECCCEEECCCHHHHHHHHHHHHCEEEEECCCCCCEEEEEEEEEEEEHHH
KMISRINYIKSLNKYIVIAGCMPKALKKKAEKINPDILIMPKEAHLIGDIIYNYFKNNIG
HHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCC
NENNADNKIEDSMKCGELPHNQASSSGNYNDIDNKLTQLKPNNLIMPLPISEGCTGKCTY
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCHHH
CIVKIARGRLASYNPDKIINKAKEFVDNGVKQMLITSQDTACYGFDKNTTLPTLLNEICQ
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCEEECCCCCCCHHHHHHHHHH
IKGDFNIRIGMMHAKNVPMIIDELIDRYKDDKITKFFHLPIQSGDDDVLRAMKREYTVDE
CCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHH
YMDIAMEFKRKIKDLNFNTDVIVGFPTETEDNFNNTIELLKKLKPDAIHGAKYTQRKGTE
HHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHCCCCC
ADRLKQVDTKIRKERMKILDKLRKEFSLENHEKYVGKIMPCLIVGKNEGITHNCKTVKFE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECCCCCCCCCCEEEEC
NCEDVKIGEFRKIKIKEALTFGLYGEIIN
CCCCCCCCCEEEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLKTLKIFIEGYGCTLNTADTNIINNSIKKFKNFIIVNNLDDADIVVINTCVVRLETEH
CCCEEEEEEEEECCCEEECCCHHHHHHHHHHHHCEEEEECCCCCCEEEEEEEEEEEEHHH
KMISRINYIKSLNKYIVIAGCMPKALKKKAEKINPDILIMPKEAHLIGDIIYNYFKNNIG
HHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCC
NENNADNKIEDSMKCGELPHNQASSSGNYNDIDNKLTQLKPNNLIMPLPISEGCTGKCTY
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCHHH
CIVKIARGRLASYNPDKIINKAKEFVDNGVKQMLITSQDTACYGFDKNTTLPTLLNEICQ
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCEEECCCCCCCHHHHHHHHHH
IKGDFNIRIGMMHAKNVPMIIDELIDRYKDDKITKFFHLPIQSGDDDVLRAMKREYTVDE
CCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHH
YMDIAMEFKRKIKDLNFNTDVIVGFPTETEDNFNNTIELLKKLKPDAIHGAKYTQRKGTE
HHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHCCCCC
ADRLKQVDTKIRKERMKILDKLRKEFSLENHEKYVGKIMPCLIVGKNEGITHNCKTVKFE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECCCCCCCCCCEEEEC
NCEDVKIGEFRKIKIKEALTFGLYGEIIN
CCCCCCCCCEEEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]