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The map label for this gene is idsA [H]

Identifier: 150401609

GI number: 150401609

Start: 1252912

End: 1253874

Strand: Direct

Name: idsA [H]

Synonym: Maeo_1186

Alternate gene names: 150401609

Gene position: 1252912-1253874 (Clockwise)

Preceding gene: 150401608

Following gene: 150401611

Centisome position: 79.83

GC content: 32.5

Gene sequence:

>963_bases
ATGGAATTATTTGACAAAACCATATTATTGAAAATTGAGGAAGAATTAAATAGACAAGTAAATAAAGAAGGCAAGCTATA
TGAAGCATCGAAACATCTTTTATTTGCAGGGGGTAAAAGAATTAGGCCTTATCTGTCTGTTTTAACCTATCTATTAAAGA
AAGATGATATTGATGAGGTTCTAACCCCTGCTGTCTCTGTGGAATTAATCCATGGTTATTCCCTTATCCATGACGATATT
ATGGATAATGACAGTGAAAGGAGAGGAAAACCTACTGTTCATATAGTATATGGGGAACCTATTGCAATTCTTGCAGGGGA
TTTACTTAATACTTTGGCATTTAATGCAATTTCTCAAATGGAGAATTTAGAAAAGGCACACGAAATATTAAAAATAGTAA
GTAAAGCATCTGTGAAGGTTTGCGAAGGGCAGGCAACAGATATGGAATTCGAAGAAAGAGAAGTAATTCCTACAATTGAT
GAATATTTTGACATGATTTCAAAGAAGACAGGAGCATTAATTGTAGCACCTATTGAAATAGGGGCAGTAATGGCAGATTT
TACCGAAGAAGAAAGAAAGGCAATATGCGAATATGCTAAAAGAATAGGTATGACATTCCAAATACAGGATGATGTTCTTG
ATTTAATCGGGGATAAAAATACCATTGGAAAACCAGTTGGAAGCGATATAGTGGAAGGTAAAAAAACTATTATGGTATTA
CATGCACTTCAAACACTTCCAGAGCCTGAAAAACAAAGGTTTTTAAAAATATTAGGAAATAGCAATGCAACAGATGAAGA
AATTAAAGAAGCTATTGAAATGTTGGGCCCTTCTATTAATTATGCAAAAGATATTATGAAAACTGCCACAATAGAAGCAA
AAGATTATTTAAAAATATTTGATGAAGAAAAAAGGAAAAGATTAGAAAATATCGCTGAGTTTATAATTGAACGGGTTTTC
TAA

Upstream 100 bases:

>100_bases
ACAAATATATTGACATACTATGGAAAAACACAATATATATCCTATCTAATTTTTTAATAAATTTATATTTTTATCATATA
TTGCCATATGGGGTGAAATC

Downstream 100 bases:

>100_bases
AAATACATTAAATATATATGTATATATTTTATTTTTTTTACTATCTATCGTGCTCCCAATATATTGCATCCAACAATATG
GCAACAGGAGCTCCCATAGT

Product: polyprenyl synthetase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MELFDKTILLKIEEELNRQVNKEGKLYEASKHLLFAGGKRIRPYLSVLTYLLKKDDIDEVLTPAVSVELIHGYSLIHDDI
MDNDSERRGKPTVHIVYGEPIAILAGDLLNTLAFNAISQMENLEKAHEILKIVSKASVKVCEGQATDMEFEEREVIPTID
EYFDMISKKTGALIVAPIEIGAVMADFTEEERKAICEYAKRIGMTFQIQDDVLDLIGDKNTIGKPVGSDIVEGKKTIMVL
HALQTLPEPEKQRFLKILGNSNATDEEIKEAIEMLGPSINYAKDIMKTATIEAKDYLKIFDEEKRKRLENIAEFIIERVF

Sequences:

>Translated_320_residues
MELFDKTILLKIEEELNRQVNKEGKLYEASKHLLFAGGKRIRPYLSVLTYLLKKDDIDEVLTPAVSVELIHGYSLIHDDI
MDNDSERRGKPTVHIVYGEPIAILAGDLLNTLAFNAISQMENLEKAHEILKIVSKASVKVCEGQATDMEFEEREVIPTID
EYFDMISKKTGALIVAPIEIGAVMADFTEEERKAICEYAKRIGMTFQIQDDVLDLIGDKNTIGKPVGSDIVEGKKTIMVL
HALQTLPEPEKQRFLKILGNSNATDEEIKEAIEMLGPSINYAKDIMKTATIEAKDYLKIFDEEKRKRLENIAEFIIERVF
>Mature_320_residues
MELFDKTILLKIEEELNRQVNKEGKLYEASKHLLFAGGKRIRPYLSVLTYLLKKDDIDEVLTPAVSVELIHGYSLIHDDI
MDNDSERRGKPTVHIVYGEPIAILAGDLLNTLAFNAISQMENLEKAHEILKIVSKASVKVCEGQATDMEFEEREVIPTID
EYFDMISKKTGALIVAPIEIGAVMADFTEEERKAICEYAKRIGMTFQIQDDVLDLIGDKNTIGKPVGSDIVEGKKTIMVL
HALQTLPEPEKQRFLKILGNSNATDEEIKEAIEMLGPSINYAKDIMKTATIEAKDYLKIFDEEKRKRLENIAEFIIERVF

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI4758430, Length=276, Percent_Identity=27.1739130434783, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI83700220, Length=276, Percent_Identity=27.1739130434783, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI50659086, Length=185, Percent_Identity=32.972972972973, Blast_Score=98, Evalue=8e-21,
Organism=Escherichia coli, GI1786623, Length=219, Percent_Identity=39.7260273972603, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789578, Length=312, Percent_Identity=29.8076923076923, Blast_Score=134, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17505681, Length=194, Percent_Identity=30.4123711340206, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17508563, Length=229, Percent_Identity=31.0043668122271, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6325188, Length=241, Percent_Identity=27.8008298755187, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319475, Length=224, Percent_Identity=27.2321428571429, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24651612, Length=219, Percent_Identity=26.9406392694064, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281365769, Length=232, Percent_Identity=28.0172413793103, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24660002, Length=232, Percent_Identity=28.0172413793103, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17137582, Length=265, Percent_Identity=27.9245283018868, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 36232; Mature: 36232

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELFDKTILLKIEEELNRQVNKEGKLYEASKHLLFAGGKRIRPYLSVLTYLLKKDDIDEV
CCCHHHHHHHHHHHHHHHHHCCCCCEEHHCCHHEEECCCHHHHHHHHHHHHHCCCCHHHH
LTPAVSVELIHGYSLIHDDIMDNDSERRGKPTVHIVYGEPIAILAGDLLNTLAFNAISQM
HCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
ENLEKAHEILKIVSKASVKVCEGQATDMEFEEREVIPTIDEYFDMISKKTGALIVAPIEI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCCEEEEEHHH
GAVMADFTEEERKAICEYAKRIGMTFQIQDDVLDLIGDKNTIGKPVGSDIVEGKKTIMVL
HHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHH
HALQTLPEPEKQRFLKILGNSNATDEEIKEAIEMLGPSINYAKDIMKTATIEAKDYLKIF
HHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHH
DEEKRKRLENIAEFIIERVF
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELFDKTILLKIEEELNRQVNKEGKLYEASKHLLFAGGKRIRPYLSVLTYLLKKDDIDEV
CCCHHHHHHHHHHHHHHHHHCCCCCEEHHCCHHEEECCCHHHHHHHHHHHHHCCCCHHHH
LTPAVSVELIHGYSLIHDDIMDNDSERRGKPTVHIVYGEPIAILAGDLLNTLAFNAISQM
HCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
ENLEKAHEILKIVSKASVKVCEGQATDMEFEEREVIPTIDEYFDMISKKTGALIVAPIEI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCCEEEEEHHH
GAVMADFTEEERKAICEYAKRIGMTFQIQDDVLDLIGDKNTIGKPVGSDIVEGKKTIMVL
HHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHH
HALQTLPEPEKQRFLKILGNSNATDEEIKEAIEMLGPSINYAKDIMKTATIEAKDYLKIF
HHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHH
DEEKRKRLENIAEFIIERVF
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]