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The map label for this gene is cysH [C]

Identifier: 150401600

GI number: 150401600

Start: 1243789

End: 1245318

Strand: Direct

Name: cysH [C]

Synonym: Maeo_1177

Alternate gene names: 150401600

Gene position: 1243789-1245318 (Clockwise)

Preceding gene: 150401599

Following gene: 150401601

Centisome position: 79.25

GC content: 31.37

Gene sequence:

>1530_bases
ATGAAGACAATATTGGGAAAATTGCATTTAAGATGGTGTATGGATTGTAATATGCCTGTTCTTGATAAAAAATGTGGAAT
ATGTGGAAAAAACACAACGGAGGTAAAAATAACTCCACCAGCCGACCCGAGACCAGCATTTGACGAAGATATAACCATGA
TAAGTAAAATATTAAAAAATCAATTTGGAATAACATTAAATAACAACGGACAAAGCAATATATTCAAAAATAAAATAGTT
TTAATAAATAAAATCCCTGGAACTGACTATATGAAAGAGATAATGTTGGATGGGATATTATTTGGGATTATAAAATATAA
CGAGGAAAAAAACACATGGGTAATAATGCCATCTGTTGATGGGGCTCGTAGAATAATCAATGAAAATGCCAATAAAAAAT
TAATTGTAATAAATAGAGAAGTAATACCATTTGTATTAAAAAAACATGCTTCTATATTAAGACCGGGAGTAATATGGGCA
TCAGAAGATATTGAAGTTGAAGATGATGTAATAATATTGGTTGAAAATGATAATAACAAAAACAACGACGATTTTAAAGA
TATTGATGTTTTAGGTGTTGGAAGAAGTAGAATGAGCTACCATGAAATAGTCAATTCAGAAAAAGGAATGGTAGCAAAAG
TTAGAAAATCCGAAAACCCGAAACCTGCAAATATATTGAAAGAAACAGGAGCTCCCAGCGAAAACATTGAAAAAATGATT
GAAGCTAATAAGGAACCAATGGCTAAATTTATTAATAATTCCGTAGGTTTTATGAGGAACACCATAAAAGAGCGAACAAA
TAAACCGCCAGTTGTGGCATATTCGGGCGGAAAAGATAGTCTTGCCGTGTTATTATTGGCATTTGAGGCATTTAACAATG
AAAATATAAACTTTGATGTAATATTTTCGGATACAGAATTGGAACTCCCTGAAACTTTAAAAAATATACAGGATATTGAG
GAAACATACGGCATAAACATAATAACGGCAAAATCTACGGAATTTTGGAAGAAATTGGAAGAAATGGGCCCTCCTGGTAG
AGATAATAGGTGGTGCAGTGAAGTATGTAAAATGAAGCCACTTGAAAAAATAATAAATGAAAAATATGAAAAAGGTTGTT
TAACTTTTGTAGGGCTTAGGAAATATGAATCAATGAATCGTTCAAAAAAGCCGAGAATTTGGAGAAGTCCTCACATTAAA
AAACAAATGTTATCAGCACCAATATTAAATTGGACGGCTATGCATGTTTGGATATATTTGTTTATGAAAGGAGCTCCCTA
CAATAAATTATATGAGCAATGTTTTGATAGGGTAGGATGTTATATGTGTCCAGCTATGGAATTGGGGGAAATGGAGCTAA
TTAGAAATATTTATCCTGACTATTGGAAAAAATGGGATAATTTTTTAGAAAAATATGCAGAAACTCACAATTTGGATGAT
AATTGGATTAAAAGCGGTTGGAGATGGTCATATAAACAAGAAAATAACAAAAATAATATTCAGGATAAAAGTATGGGAAC
TTATGAATAA

Upstream 100 bases:

>100_bases
GTTGGAATTAAAATGGTAATTTAAAATAATAAATTATTAATAAAAAATTAACCTATAATTAATATTATAAATATTATAAT
TAAATAAAAAAGGTAGAATT

Downstream 100 bases:

>100_bases
TATAAATACAAATATAATATTATATAATAAATAATTATAAAATATAATATAAATATTTTATGCGCCAATAGATAATAAAG
AACATAATTAAAAATCAATA

Product: hypothetical protein

Products: diphosphate; adenylylsulfate

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MKTILGKLHLRWCMDCNMPVLDKKCGICGKNTTEVKITPPADPRPAFDEDITMISKILKNQFGITLNNNGQSNIFKNKIV
LINKIPGTDYMKEIMLDGILFGIIKYNEEKNTWVIMPSVDGARRIINENANKKLIVINREVIPFVLKKHASILRPGVIWA
SEDIEVEDDVIILVENDNNKNNDDFKDIDVLGVGRSRMSYHEIVNSEKGMVAKVRKSENPKPANILKETGAPSENIEKMI
EANKEPMAKFINNSVGFMRNTIKERTNKPPVVAYSGGKDSLAVLLLAFEAFNNENINFDVIFSDTELELPETLKNIQDIE
ETYGINIITAKSTEFWKKLEEMGPPGRDNRWCSEVCKMKPLEKIINEKYEKGCLTFVGLRKYESMNRSKKPRIWRSPHIK
KQMLSAPILNWTAMHVWIYLFMKGAPYNKLYEQCFDRVGCYMCPAMELGEMELIRNIYPDYWKKWDNFLEKYAETHNLDD
NWIKSGWRWSYKQENNKNNIQDKSMGTYE

Sequences:

>Translated_509_residues
MKTILGKLHLRWCMDCNMPVLDKKCGICGKNTTEVKITPPADPRPAFDEDITMISKILKNQFGITLNNNGQSNIFKNKIV
LINKIPGTDYMKEIMLDGILFGIIKYNEEKNTWVIMPSVDGARRIINENANKKLIVINREVIPFVLKKHASILRPGVIWA
SEDIEVEDDVIILVENDNNKNNDDFKDIDVLGVGRSRMSYHEIVNSEKGMVAKVRKSENPKPANILKETGAPSENIEKMI
EANKEPMAKFINNSVGFMRNTIKERTNKPPVVAYSGGKDSLAVLLLAFEAFNNENINFDVIFSDTELELPETLKNIQDIE
ETYGINIITAKSTEFWKKLEEMGPPGRDNRWCSEVCKMKPLEKIINEKYEKGCLTFVGLRKYESMNRSKKPRIWRSPHIK
KQMLSAPILNWTAMHVWIYLFMKGAPYNKLYEQCFDRVGCYMCPAMELGEMELIRNIYPDYWKKWDNFLEKYAETHNLDD
NWIKSGWRWSYKQENNKNNIQDKSMGTYE
>Mature_509_residues
MKTILGKLHLRWCMDCNMPVLDKKCGICGKNTTEVKITPPADPRPAFDEDITMISKILKNQFGITLNNNGQSNIFKNKIV
LINKIPGTDYMKEIMLDGILFGIIKYNEEKNTWVIMPSVDGARRIINENANKKLIVINREVIPFVLKKHASILRPGVIWA
SEDIEVEDDVIILVENDNNKNNDDFKDIDVLGVGRSRMSYHEIVNSEKGMVAKVRKSENPKPANILKETGAPSENIEKMI
EANKEPMAKFINNSVGFMRNTIKERTNKPPVVAYSGGKDSLAVLLLAFEAFNNENINFDVIFSDTELELPETLKNIQDIE
ETYGINIITAKSTEFWKKLEEMGPPGRDNRWCSEVCKMKPLEKIINEKYEKGCLTFVGLRKYESMNRSKKPRIWRSPHIK
KQMLSAPILNWTAMHVWIYLFMKGAPYNKLYEQCFDRVGCYMCPAMELGEMELIRNIYPDYWKKWDNFLEKYAETHNLDD
NWIKSGWRWSYKQENNKNNIQDKSMGTYE

Specific function: Reduction Of Activated Sulfate Into Sulfite. [C]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PUA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002500
- InterPro:   IPR002478
- InterPro:   IPR015947
- InterPro:   IPR014729
- InterPro:   IPR004521 [H]

Pfam domain/function: PF01507 PAPS_reduct; PF01472 PUA [H]

EC number: 2.7.7.4

Molecular weight: Translated: 58940; Mature: 58940

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50890 PUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTILGKLHLRWCMDCNMPVLDKKCGICGKNTTEVKITPPADPRPAFDEDITMISKILKN
CCCHHHHHHHHHEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
QFGITLNNNGQSNIFKNKIVLINKIPGTDYMKEIMLDGILFGIIKYNEEKNTWVIMPSVD
HCCEEECCCCCCCEECCEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCC
GARRIINENANKKLIVINREVIPFVLKKHASILRPGVIWASEDIEVEDDVIILVENDNNK
HHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCC
NNDDFKDIDVLGVGRSRMSYHEIVNSEKGMVAKVRKSENPKPANILKETGAPSENIEKMI
CCCCCCCEEEEECCCHHHHHHHHHCCCCCCEEEHHCCCCCCHHHHHHHCCCCHHHHHHHH
EANKEPMAKFINNSVGFMRNTIKERTNKPPVVAYSGGKDSLAVLLLAFEAFNNENINFDV
HCCHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEE
IFSDTELELPETLKNIQDIEETYGINIITAKSTEFWKKLEEMGPPGRDNRWCSEVCKMKP
EECCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHCCCH
LEKIINEKYEKGCLTFVGLRKYESMNRSKKPRIWRSPHIKKQMLSAPILNWTAMHVWIYL
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHH
FMKGAPYNKLYEQCFDRVGCYMCPAMELGEMELIRNIYPDYWKKWDNFLEKYAETHNLDD
HHCCCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCH
NWIKSGWRWSYKQENNKNNIQDKSMGTYE
HHHCCCCEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTILGKLHLRWCMDCNMPVLDKKCGICGKNTTEVKITPPADPRPAFDEDITMISKILKN
CCCHHHHHHHHHEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
QFGITLNNNGQSNIFKNKIVLINKIPGTDYMKEIMLDGILFGIIKYNEEKNTWVIMPSVD
HCCEEECCCCCCCEECCEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCC
GARRIINENANKKLIVINREVIPFVLKKHASILRPGVIWASEDIEVEDDVIILVENDNNK
HHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCC
NNDDFKDIDVLGVGRSRMSYHEIVNSEKGMVAKVRKSENPKPANILKETGAPSENIEKMI
CCCCCCCEEEEECCCHHHHHHHHHCCCCCCEEEHHCCCCCCHHHHHHHCCCCHHHHHHHH
EANKEPMAKFINNSVGFMRNTIKERTNKPPVVAYSGGKDSLAVLLLAFEAFNNENINFDV
HCCHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEE
IFSDTELELPETLKNIQDIEETYGINIITAKSTEFWKKLEEMGPPGRDNRWCSEVCKMKP
EECCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHCCCH
LEKIINEKYEKGCLTFVGLRKYESMNRSKKPRIWRSPHIKKQMLSAPILNWTAMHVWIYL
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHH
FMKGAPYNKLYEQCFDRVGCYMCPAMELGEMELIRNIYPDYWKKWDNFLEKYAETHNLDD
HHCCCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCH
NWIKSGWRWSYKQENNKNNIQDKSMGTYE
HHHCCCCEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; sulfate

Specific reaction: ATP + sulfate = diphosphate + adenylylsulfate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]