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The map label for this gene is 150401588

Identifier: 150401588

GI number: 150401588

Start: 1222517

End: 1223263

Strand: Direct

Name: 150401588

Synonym: Maeo_1165

Alternate gene names: NA

Gene position: 1222517-1223263 (Clockwise)

Preceding gene: 150401587

Following gene: 150401591

Centisome position: 77.89

GC content: 35.34

Gene sequence:

>747_bases
ATGTTTGGAAAAGTTGAAGAAAAATTAAATAATGTATTAAAAACAGAGGGAGCTCTCTATTTTATACTCATAGACCCAGA
CGAAAAAAACTGTTTAGAAATAGCGGAAAAGGTAAAAGATTATGCAGACGCCATAATACTCGGAGGTAGCATAGGCATCA
CAAATTTGGACGAAACTACAAAGCAAATCAAAGAAATTATTGGGGATATTCCTATTATATTATTTCCCGGAAATGTAGAT
GGTTTAACCCCTTATGCTGATGCAGTGTTTTTTATGAGTTTTATGAATTCAAATAATACTTATTGGACTACAACGGCACC
AACATTAGGGGCAATTACTGTAAAAAAATATAACTTAGAACCTATCTCAATGGCTTATTTAGGTATTGAACCTATAAAAA
GAACAGCCGTTGGATTTGTTGGCGAAGTAAATGAGATACCACAGCGAAAACCTGAAATAGCAGGAATGTATTGTCTATCA
GCTAAATACTTTGGTATGAGGTGGGCATATTTGGAGGCAGGAAGTGGTGCGGAGCTCCCCGTTAGTAATGAAATTATAGG
CATATCAAAAAAGTTGAGCGGAATAAATATTATTGTGGGCGGAGGGATAAGAACACCTGAAACAGCATATCAAAAGGTTT
TAAGTGGTGCTGATGCCATAGTCACAGGAACACTTATTGAAGATAATCCCGATGCAGTAAAAGAAATGAGAAATGCCATT
AAAAAAGCAGGAATAGATAAATTATAG

Upstream 100 bases:

>100_bases
TAAAGTAAAATTAAAAATAGATACTAATGCTAGACATTTTGGAATGGCTATACAAGAAACAATAATTGAAAAATAAATAT
TTAGTGTATGAGGAACAAAA

Downstream 100 bases:

>100_bases
TTAATCTTCAATAACCGTCCCTTATCCGCCCTAATATATTAAATAAAATCTCTTCGAGATTTTTTCGTGTTCCTTAATTC
GATAGGATGGTGTAGTTTAA

Product: geranylgeranylglyceryl phosphate synthase-like protein

Products: NA

Alternate protein names: GGGP synthase; GGGPS; (S)-3-O-geranylgeranylglyceryl phosphate synthase; Phosphoglycerol geranylgeranyltransferase

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MFGKVEEKLNNVLKTEGALYFILIDPDEKNCLEIAEKVKDYADAIILGGSIGITNLDETTKQIKEIIGDIPIILFPGNVD
GLTPYADAVFFMSFMNSNNTYWTTTAPTLGAITVKKYNLEPISMAYLGIEPIKRTAVGFVGEVNEIPQRKPEIAGMYCLS
AKYFGMRWAYLEAGSGAELPVSNEIIGISKKLSGINIIVGGGIRTPETAYQKVLSGADAIVTGTLIEDNPDAVKEMRNAI
KKAGIDKL

Sequences:

>Translated_248_residues
MFGKVEEKLNNVLKTEGALYFILIDPDEKNCLEIAEKVKDYADAIILGGSIGITNLDETTKQIKEIIGDIPIILFPGNVD
GLTPYADAVFFMSFMNSNNTYWTTTAPTLGAITVKKYNLEPISMAYLGIEPIKRTAVGFVGEVNEIPQRKPEIAGMYCLS
AKYFGMRWAYLEAGSGAELPVSNEIIGISKKLSGINIIVGGGIRTPETAYQKVLSGADAIVTGTLIEDNPDAVKEMRNAI
KKAGIDKL
>Mature_248_residues
MFGKVEEKLNNVLKTEGALYFILIDPDEKNCLEIAEKVKDYADAIILGGSIGITNLDETTKQIKEIIGDIPIILFPGNVD
GLTPYADAVFFMSFMNSNNTYWTTTAPTLGAITVKKYNLEPISMAYLGIEPIKRTAVGFVGEVNEIPQRKPEIAGMYCLS
AKYFGMRWAYLEAGSGAELPVSNEIIGISKKLSGINIIVGGGIRTPETAYQKVLSGADAIVTGTLIEDNPDAVKEMRNAI
KKAGIDKL

Specific function: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membr

COG id: COG1646

COG function: function code R; Predicted phosphate-binding enzymes, TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GGGP synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GGGPS_META3 (A6UW70)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325354.1
- ProteinModelPortal:   A6UW70
- SMR:   A6UW70
- STRING:   A6UW70
- GeneID:   5327712
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1165
- eggNOG:   arNOG05493
- HOGENOM:   HBG313841
- OMA:   ADAIFFM
- ProtClustDB:   PRK04169
- BioCyc:   MAEO419665:MAEO_1165-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00112
- InterPro:   IPR008205
- InterPro:   IPR010946
- Gene3D:   G3DSA:3.20.20.390
- TIGRFAMs:   TIGR01769
- TIGRFAMs:   TIGR01768

Pfam domain/function: PF01884 PcrB

EC number: =2.5.1.41

Molecular weight: Translated: 26934; Mature: 26934

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: BINDING 202-202

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGKVEEKLNNVLKTEGALYFILIDPDEKNCLEIAEKVKDYADAIILGGSIGITNLDETT
CCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCEEEECCCCCCCCCHHHH
KQIKEIIGDIPIILFPGNVDGLTPYADAVFFMSFMNSNNTYWTTTAPTLGAITVKKYNLE
HHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCC
PISMAYLGIEPIKRTAVGFVGEVNEIPQRKPEIAGMYCLSAKYFGMRWAYLEAGSGAELP
CEEEEEECCCHHHHHHHHHHCCHHHCCCCCCCHHEEEEEEHHHHCEEEEEEECCCCCCCC
VSNEIIGISKKLSGINIIVGGGIRTPETAYQKVLSGADAIVTGTLIEDNPDAVKEMRNAI
CCCCEEEEHHCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHH
KKAGIDKL
HHCCCCCC
>Mature Secondary Structure
MFGKVEEKLNNVLKTEGALYFILIDPDEKNCLEIAEKVKDYADAIILGGSIGITNLDETT
CCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCEEEECCCCCCCCCHHHH
KQIKEIIGDIPIILFPGNVDGLTPYADAVFFMSFMNSNNTYWTTTAPTLGAITVKKYNLE
HHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCC
PISMAYLGIEPIKRTAVGFVGEVNEIPQRKPEIAGMYCLSAKYFGMRWAYLEAGSGAELP
CEEEEEECCCHHHHHHHHHHCCHHHCCCCCCCHHEEEEEEHHHHCEEEEEEECCCCCCCC
VSNEIIGISKKLSGINIIVGGGIRTPETAYQKVLSGADAIVTGTLIEDNPDAVKEMRNAI
CCCCEEEEHHCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHH
KKAGIDKL
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA