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The map label for this gene is mptA

Identifier: 150401571

GI number: 150401571

Start: 1205647

End: 1206576

Strand: Direct

Name: mptA

Synonym: Maeo_1148

Alternate gene names: 150401571

Gene position: 1205647-1206576 (Clockwise)

Preceding gene: 150401570

Following gene: 150401572

Centisome position: 76.82

GC content: 33.01

Gene sequence:

>930_bases
ATGTTTTGTGATGTTCAAGCAACGGAACCTGATGTAAAGGTATCATTAACAAGGGTAGGAATTACAAATTTAAAAAAACT
AATTAAAATTACAAGGGAATCAAAAAGACCCATAATATTGCTTCCAACTTTTGAAGTTTTTGTAGATTTACCAAGCTCCC
AAAAGGGAATACATATGTCAAGAAGTCCAGAAGTAATTGAAGAAATTATAGAATCTATGGTCGATAATGAAGTATATGGA
ATTGAAGAACTTTCTGTGGACATTATAAAAAAATTGTTCGAAAAACACGAATATGCGACAAGGGCAGAAGTTTTAATGTA
TGGAGAATATATGATGGAGGAAGAATCCCCCATCACTAAGCGGAGCTCCCAAGAAATTTGTAAAATTATGTCGAAAGCTC
ATGGTACAAAGGATGGGAATAACAATATAATAATTAAAAAAATGGTGGGGGCTGAGGTTGTAGGTATCACAGCATGTCCT
TGTGCTCAAAATCTTTTAAAAGAAAAAGCCATTAAAAAATTAAAAGAAAAAGGATTTTCTGATGAAGATATTAAAAATAT
ACTGGATTCTGTCTCAATAGCCACCCATAACCAAAGAGGAATTGGAACAATTATGATTGAAGTGCCTGATGGTTATGAAG
TGGGCATTTCTAAAATTATAAATATTATTAAAAAATCAATGAGTGGGGAAGTATATGAGCTTTTAAAACGAGTTGATGAA
GGATATGTCGTAGAGGAAGCACATAAAAATCCAAAATTTGTTGAAGATTGTGCAAGAGAAATGATAAGAAGAGTTGTTGG
AGAGTTTAACTATCTTCCAGATGATACAGAAGTATTGGTAAGACAAGTCAATAAAGAAAGTATCCATAGGCATGATGCTT
TCGCAGAGCGGAGCTCCACATTAGGGGAGTTAAGAAATGAATTGAAATAA

Upstream 100 bases:

>100_bases
ATGTTAATGTAATAGTTATATGGTCAATGACATATATAGTTAAATAGGATTATATGTGTAATATGGTGTAAATATATTTT
TAATAATTATCGGTGAAATA

Downstream 100 bases:

>100_bases
CATACACGAATAAGTAAAATTTTGAGATTTTTTTATCTTTTTATTTTTATGGTTTGTTCGGGAACTCATTATGGATATTT
TAAGCATATTTTCATTAATC

Product: GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MFCDVQATEPDVKVSLTRVGITNLKKLIKITRESKRPIILLPTFEVFVDLPSSQKGIHMSRSPEVIEEIIESMVDNEVYG
IEELSVDIIKKLFEKHEYATRAEVLMYGEYMMEEESPITKRSSQEICKIMSKAHGTKDGNNNIIIKKMVGAEVVGITACP
CAQNLLKEKAIKKLKEKGFSDEDIKNILDSVSIATHNQRGIGTIMIEVPDGYEVGISKIINIIKKSMSGEVYELLKRVDE
GYVVEEAHKNPKFVEDCAREMIRRVVGEFNYLPDDTEVLVRQVNKESIHRHDAFAERSSTLGELRNELK

Sequences:

>Translated_309_residues
MFCDVQATEPDVKVSLTRVGITNLKKLIKITRESKRPIILLPTFEVFVDLPSSQKGIHMSRSPEVIEEIIESMVDNEVYG
IEELSVDIIKKLFEKHEYATRAEVLMYGEYMMEEESPITKRSSQEICKIMSKAHGTKDGNNNIIIKKMVGAEVVGITACP
CAQNLLKEKAIKKLKEKGFSDEDIKNILDSVSIATHNQRGIGTIMIEVPDGYEVGISKIINIIKKSMSGEVYELLKRVDE
GYVVEEAHKNPKFVEDCAREMIRRVVGEFNYLPDDTEVLVRQVNKESIHRHDAFAERSSTLGELRNELK
>Mature_309_residues
MFCDVQATEPDVKVSLTRVGITNLKKLIKITRESKRPIILLPTFEVFVDLPSSQKGIHMSRSPEVIEEIIESMVDNEVYG
IEELSVDIIKKLFEKHEYATRAEVLMYGEYMMEEESPITKRSSQEICKIMSKAHGTKDGNNNIIIKKMVGAEVVGITACP
CAQNLLKEKAIKKLKEKGFSDEDIKNILDSVSIATHNQRGIGTIMIEVPDGYEVGISKIINIIKKSMSGEVYELLKRVDE
GYVVEEAHKNPKFVEDCAREMIRRVVGEFNYLPDDTEVLVRQVNKESIHRHDAFAERSSTLGELRNELK

Specific function: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MPTA_META3 (A6UW53)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325337.1
- ProteinModelPortal:   A6UW53
- SMR:   A6UW53
- STRING:   A6UW53
- GeneID:   5327356
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1148
- eggNOG:   arNOG04823
- HOGENOM:   HBG626871
- OMA:   ACPCAQN
- ProtClustDB:   PRK13675
- BioCyc:   MAEO419665:MAEO_1148-MONOMER
- HAMAP:   MF_01527_A
- InterPro:   IPR003801
- InterPro:   IPR022840
- InterPro:   IPR002042
- Gene3D:   G3DSA:3.10.270.10
- TIGRFAMs:   TIGR00294

Pfam domain/function: PF02649 DUF198

EC number: NA

Molecular weight: Translated: 35046; Mature: 35046

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFCDVQATEPDVKVSLTRVGITNLKKLIKITRESKRPIILLPTFEVFVDLPSSQKGIHMS
CCCCCCCCCCCCEEEEEHHCHHHHHHHHHHHHHCCCCEEEEEHHHHEEECCCCCCCCCCC
RSPEVIEEIIESMVDNEVYGIEELSVDIIKKLFEKHEYATRAEVLMYGEYMMEEESPITK
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RSSQEICKIMSKAHGTKDGNNNIIIKKMVGAEVVGITACPCAQNLLKEKAIKKLKEKGFS
CCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHCCCC
DEDIKNILDSVSIATHNQRGIGTIMIEVPDGYEVGISKIINIIKKSMSGEVYELLKRVDE
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
GYVVEEAHKNPKFVEDCAREMIRRVVGEFNYLPDDTEVLVRQVNKESIHRHDAFAERSST
CCEEHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGELRNELK
HHHHHHHCC
>Mature Secondary Structure
MFCDVQATEPDVKVSLTRVGITNLKKLIKITRESKRPIILLPTFEVFVDLPSSQKGIHMS
CCCCCCCCCCCCEEEEEHHCHHHHHHHHHHHHHCCCCEEEEEHHHHEEECCCCCCCCCCC
RSPEVIEEIIESMVDNEVYGIEELSVDIIKKLFEKHEYATRAEVLMYGEYMMEEESPITK
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RSSQEICKIMSKAHGTKDGNNNIIIKKMVGAEVVGITACPCAQNLLKEKAIKKLKEKGFS
CCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHCCCC
DEDIKNILDSVSIATHNQRGIGTIMIEVPDGYEVGISKIINIIKKSMSGEVYELLKRVDE
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
GYVVEEAHKNPKFVEDCAREMIRRVVGEFNYLPDDTEVLVRQVNKESIHRHDAFAERSST
CCEEHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGELRNELK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA