Click here to switch to the map view.

The map label for this gene is moeA [C]

Identifier: 150401547

GI number: 150401547

Start: 1168668

End: 1170674

Strand: Reverse

Name: moeA [C]

Synonym: Maeo_1124

Alternate gene names: 150401547

Gene position: 1170674-1168668 (Counterclockwise)

Preceding gene: 150401549

Following gene: 150401531

Centisome position: 74.59

GC content: 31.29

Gene sequence:

>2007_bases
ATGAGATATTTAGAATTGAGTAGTATTGAAGAGGCTAAAAAGATAATAAATAAATTTTTAAATGAATTGCAGGACGATAA
ATACAATAAAGACAATAAAAATATTAATAACGATACCAATAATACTAACACGACTGATAAAGATAGCAATGACAAAAATA
ATGGCATAGAGGAAGTGGATTTATTTAATGCAGTAAATAGAATTTTGGCAGAGGATATAATTTCAAATGTAGATGTCCCA
CCATTTGACAGGTCAAAAATGGACGGATATGCCGTAAAATCAGAGGACACCTACGAAGCTGAGGAAGATGCCCCCATAAC
ATTAAAAATAATTGATAGAATTAAGGCGGGGTCTTATTCCACAAAAGAATTAAAAAATAATGAATGCATGGAAATAGCAA
CAGGAGCTCCCATACCAAAAGGGGCGAATGCCGTTGTAATGGTAGAATATACGGAAACAGATAATAATAATGTAAAAATT
TATAGGCCAGTTTCGCCACATGAGAATATTCAATATTGTGGTAGTGACATAATGGCAGGGGAGCTCCTTTTAAGAAAAGA
TACACCACTATCCCCAAGGGATATAGGGGCATTACCTTCAATTGGTAAAAGCAATATAAAAGTTTATAAAAAACCCCCCC
ACCATCATATAAAACAAGAATTAAAATCAAAAATAAATATTGGATTAATATCCACCGGAAACGAGCTAATAAGTCCAAAT
GAACCATTATCTCCCTATAAAATATATGATGTAAACACCTATACAATAGCTTCTTCAATAATTGAAAAAGGCTGGGATTT
TAAATTTTACGGCATAGTTAAAGATAATGAGGAGGATTTAAAAAATAGTATTAAAAAAGCTTTACAGGGCAATAATGATA
TTATTATATTAAGTGGTGGAACTTCCGCAGGTGTTGGAGATTTAACTTCTAAAATAATTGAAGAATTGGGCGGGGAAATA
CTAATACACGGCATAAAGATAAAACCGGGAAAACCAACCATAATCGGGAAGATAGATAATAAATTAATAGTGGGACTTCC
TGGGTATCCCACATCCTGTTTAACCATTTTTGATGTATTATTTAATGAAATGGGAAATAAACTAACAGGACTATTTCCAA
TTAGATATATGTCTTCAAAGGGAAGGACAGAATATTTGCCTGTATCTGTGATGCGGGAAAAAGATAATAACTATATAATT
TACCCCATTACAAAGGGAAGCGGAGCCATAACCTCTTTAACCTATGCAGATGGATATATAGTAATTGATGAAAATAAGGA
AATTCTGGAAAACGAAACTGTGGAAGTCCATTTATTTGGAAATATTAAATTTGGGCTCAATATAATCGGTAGCCATTGCA
TAGGAATTGACGAAATATTAAGAAAAGGGCATATTTTTGCCAAAACAATAAATGTTGGTTCTTTGGGTGGATTAATGGCA
ATTAAACGAGGGGAAGCAGATATTTCAGGTATTCACCTATTGGACGAAAGGGCAAAAGAGGGGGAGGAACCATACAATAT
ATCATTTATTAAAAAATACAAACTTAAAGATGTGGCATTGGTTAGAGGATATGTTAGAAAACAAGGTTTTATGTTTAGAA
AGGAGCTCCCAATAAATAATATTGAAGAATTAAAAAATAATATTGAAAATTATAAATTTATTAATAGAAATAAGGGGGCA
GGAACTAGATTATTATTTGATAAATTTTTAAAAGAGAATAATATTAATAAATCAAAGATAAATGGCTATAATATTGAAGC
AAAAACTCATTCAGCAGTTGGGGCTTCCGTTGTTATGGGTAAAGTGGATATTGGAGTGGGAATTGAAACAATAGCAGAAA
AATATGGATTAAAATTTATGCCTATTGGGGACGAATATTACGATTTTCTCATTAAAAAAGATAAATTAAAAGATAAAGAG
GTTCAAAAATTCATTGAAACCTTAAAAACCATAGAATTACCATTTAGGAAATCAGAAAACACTGGAAAAATAATATATGA
ATGTTAA

Upstream 100 bases:

>100_bases
AATATAATAGAATACAATTACATTATTATTTATTCATATTATTTAAATTTATTAGGAGCTCCCAATTATCGTTATTATTA
ATTATATTTTTGGTGATATA

Downstream 100 bases:

>100_bases
AAAATTACAATGAAAATTCAAATCCGAAAGATTTAATCATAATCCTAAAATATCCTTTAAATCCATTCCTCTCATTATTT
TATTTTTTATTGATTCTTCT

Product: putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MRYLELSSIEEAKKIINKFLNELQDDKYNKDNKNINNDTNNTNTTDKDSNDKNNGIEEVDLFNAVNRILAEDIISNVDVP
PFDRSKMDGYAVKSEDTYEAEEDAPITLKIIDRIKAGSYSTKELKNNECMEIATGAPIPKGANAVVMVEYTETDNNNVKI
YRPVSPHENIQYCGSDIMAGELLLRKDTPLSPRDIGALPSIGKSNIKVYKKPPHHHIKQELKSKINIGLISTGNELISPN
EPLSPYKIYDVNTYTIASSIIEKGWDFKFYGIVKDNEEDLKNSIKKALQGNNDIIILSGGTSAGVGDLTSKIIEELGGEI
LIHGIKIKPGKPTIIGKIDNKLIVGLPGYPTSCLTIFDVLFNEMGNKLTGLFPIRYMSSKGRTEYLPVSVMREKDNNYII
YPITKGSGAITSLTYADGYIVIDENKEILENETVEVHLFGNIKFGLNIIGSHCIGIDEILRKGHIFAKTINVGSLGGLMA
IKRGEADISGIHLLDERAKEGEEPYNISFIKKYKLKDVALVRGYVRKQGFMFRKELPINNIEELKNNIENYKFINRNKGA
GTRLLFDKFLKENNINKSKINGYNIEAKTHSAVGASVVMGKVDIGVGIETIAEKYGLKFMPIGDEYYDFLIKKDKLKDKE
VQKFIETLKTIELPFRKSENTGKIIYEC

Sequences:

>Translated_668_residues
MRYLELSSIEEAKKIINKFLNELQDDKYNKDNKNINNDTNNTNTTDKDSNDKNNGIEEVDLFNAVNRILAEDIISNVDVP
PFDRSKMDGYAVKSEDTYEAEEDAPITLKIIDRIKAGSYSTKELKNNECMEIATGAPIPKGANAVVMVEYTETDNNNVKI
YRPVSPHENIQYCGSDIMAGELLLRKDTPLSPRDIGALPSIGKSNIKVYKKPPHHHIKQELKSKINIGLISTGNELISPN
EPLSPYKIYDVNTYTIASSIIEKGWDFKFYGIVKDNEEDLKNSIKKALQGNNDIIILSGGTSAGVGDLTSKIIEELGGEI
LIHGIKIKPGKPTIIGKIDNKLIVGLPGYPTSCLTIFDVLFNEMGNKLTGLFPIRYMSSKGRTEYLPVSVMREKDNNYII
YPITKGSGAITSLTYADGYIVIDENKEILENETVEVHLFGNIKFGLNIIGSHCIGIDEILRKGHIFAKTINVGSLGGLMA
IKRGEADISGIHLLDERAKEGEEPYNISFIKKYKLKDVALVRGYVRKQGFMFRKELPINNIEELKNNIENYKFINRNKGA
GTRLLFDKFLKENNINKSKINGYNIEAKTHSAVGASVVMGKVDIGVGIETIAEKYGLKFMPIGDEYYDFLIKKDKLKDKE
VQKFIETLKTIELPFRKSENTGKIIYEC
>Mature_668_residues
MRYLELSSIEEAKKIINKFLNELQDDKYNKDNKNINNDTNNTNTTDKDSNDKNNGIEEVDLFNAVNRILAEDIISNVDVP
PFDRSKMDGYAVKSEDTYEAEEDAPITLKIIDRIKAGSYSTKELKNNECMEIATGAPIPKGANAVVMVEYTETDNNNVKI
YRPVSPHENIQYCGSDIMAGELLLRKDTPLSPRDIGALPSIGKSNIKVYKKPPHHHIKQELKSKINIGLISTGNELISPN
EPLSPYKIYDVNTYTIASSIIEKGWDFKFYGIVKDNEEDLKNSIKKALQGNNDIIILSGGTSAGVGDLTSKIIEELGGEI
LIHGIKIKPGKPTIIGKIDNKLIVGLPGYPTSCLTIFDVLFNEMGNKLTGLFPIRYMSSKGRTEYLPVSVMREKDNNYII
YPITKGSGAITSLTYADGYIVIDENKEILENETVEVHLFGNIKFGLNIIGSHCIGIDEILRKGHIFAKTINVGSLGGLMA
IKRGEADISGIHLLDERAKEGEEPYNISFIKKYKLKDVALVRGYVRKQGFMFRKELPINNIEELKNNIENYKFINRNKGA
GTRLLFDKFLKENNINKSKINGYNIEAKTHSAVGASVVMGKVDIGVGIETIAEKYGLKFMPIGDEYYDFLIKKDKLKDKE
VQKFIETLKTIELPFRKSENTGKIIYEC

Specific function: Involved In The Biosynthesis Of A Demolybdo-Cofactor (Molybdopterin), Necessary For Molybdo-Enzymes. Seems To Be Involved In A Step Of Activation Of Molybdenum In The Form Of Thiomolybdenum. [C]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=341, Percent_Identity=33.1378299120235, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI10880983, Length=341, Percent_Identity=33.1378299120235, Blast_Score=165, Evalue=1e-40,
Organism=Escherichia coli, GI1787049, Length=384, Percent_Identity=32.03125, Blast_Score=184, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25147659, Length=327, Percent_Identity=29.9694189602446, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17562606, Length=148, Percent_Identity=32.4324324324324, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17136978, Length=339, Percent_Identity=29.7935103244838, Blast_Score=110, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24638841, Length=339, Percent_Identity=29.7935103244838, Blast_Score=110, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 74854; Mature: 74854

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS01079 MOCF_BIOSYNTHESIS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLELSSIEEAKKIINKFLNELQDDKYNKDNKNINNDTNNTNTTDKDSNDKNNGIEEVD
CCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LFNAVNRILAEDIISNVDVPPFDRSKMDGYAVKSEDTYEAEEDAPITLKIIDRIKAGSYS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEHHHCCCCCC
TKELKNNECMEIATGAPIPKGANAVVMVEYTETDNNNVKIYRPVSPHENIQYCGSDIMAG
HHHHCCCCCEEEECCCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCCCHHHCCCCHHCC
ELLLRKDTPLSPRDIGALPSIGKSNIKVYKKPPHHHIKQELKSKINIGLISTGNELISPN
EEEEECCCCCCCHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCEEEEECCCCCCCCC
EPLSPYKIYDVNTYTIASSIIEKGWDFKFYGIVKDNEEDLKNSIKKALQGNNDIIILSGG
CCCCCEEEEECCHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECC
TSAGVGDLTSKIIEELGGEILIHGIKIKPGKPTIIGKIDNKLIVGLPGYPTSCLTIFDVL
CCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECCCEEEEECCCCCHHHHHHHHHH
FNEMGNKLTGLFPIRYMSSKGRTEYLPVSVMREKDNNYIIYPITKGSGAITSLTYADGYI
HHHHCCCEEEEEEEEEECCCCCCEECCEEEEEECCCCEEEEEEECCCCCEEEEEEECCEE
VIDENKEILENETVEVHLFGNIKFGLNIIGSHCIGIDEILRKGHIFAKTINVGSLGGLMA
EECCCHHHHCCCCEEEEEEEEEEECCEECCCCCCCHHHHHHCCCEEEEEECCCCCCCEEE
IKRGEADISGIHLLDERAKEGEEPYNISFIKKYKLKDVALVRGYVRKQGFMFRKELPINN
EECCCCCCCCEEEEHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHCCCEEEECCCCCH
IEELKNNIENYKFINRNKGAGTRLLFDKFLKENNINKSKINGYNIEAKTHSAVGASVVMG
HHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHCCCCHHHCCCEEEEECCCCCCCCEEEEE
KVDIGVGIETIAEKYGLKFMPIGDEYYDFLIKKDKLKDKEVQKFIETLKTIELPFRKSEN
EEECCCCHHHHHHHHCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCCCCCC
TGKIIYEC
CCCEEEEC
>Mature Secondary Structure
MRYLELSSIEEAKKIINKFLNELQDDKYNKDNKNINNDTNNTNTTDKDSNDKNNGIEEVD
CCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LFNAVNRILAEDIISNVDVPPFDRSKMDGYAVKSEDTYEAEEDAPITLKIIDRIKAGSYS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEHHHCCCCCC
TKELKNNECMEIATGAPIPKGANAVVMVEYTETDNNNVKIYRPVSPHENIQYCGSDIMAG
HHHHCCCCCEEEECCCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCCCHHHCCCCHHCC
ELLLRKDTPLSPRDIGALPSIGKSNIKVYKKPPHHHIKQELKSKINIGLISTGNELISPN
EEEEECCCCCCCHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCEEEEECCCCCCCCC
EPLSPYKIYDVNTYTIASSIIEKGWDFKFYGIVKDNEEDLKNSIKKALQGNNDIIILSGG
CCCCCEEEEECCHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECC
TSAGVGDLTSKIIEELGGEILIHGIKIKPGKPTIIGKIDNKLIVGLPGYPTSCLTIFDVL
CCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECCCEEEEECCCCCHHHHHHHHHH
FNEMGNKLTGLFPIRYMSSKGRTEYLPVSVMREKDNNYIIYPITKGSGAITSLTYADGYI
HHHHCCCEEEEEEEEEECCCCCCEECCEEEEEECCCCEEEEEEECCCCCEEEEEEECCEE
VIDENKEILENETVEVHLFGNIKFGLNIIGSHCIGIDEILRKGHIFAKTINVGSLGGLMA
EECCCHHHHCCCCEEEEEEEEEEECCEECCCCCCCHHHHHHCCCEEEEEECCCCCCCEEE
IKRGEADISGIHLLDERAKEGEEPYNISFIKKYKLKDVALVRGYVRKQGFMFRKELPINN
EECCCCCCCCEEEEHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHCCCEEEECCCCCH
IEELKNNIENYKFINRNKGAGTRLLFDKFLKENNINKSKINGYNIEAKTHSAVGASVVMG
HHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHCCCCHHHCCCEEEEECCCCCCCCEEEEE
KVDIGVGIETIAEKYGLKFMPIGDEYYDFLIKKDKLKDKEVQKFIETLKTIELPFRKSEN
EEECCCCHHHHHHHHCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCCCCCC
TGKIIYEC
CCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]