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The map label for this gene is trpA [H]

Identifier: 150401545

GI number: 150401545

Start: 1167230

End: 1167982

Strand: Direct

Name: trpA [H]

Synonym: Maeo_1122

Alternate gene names: 150401545

Gene position: 1167230-1167982 (Clockwise)

Preceding gene: 150401544

Following gene: 150401546

Centisome position: 74.37

GC content: 33.6

Gene sequence:

>753_bases
ATGGATAAAAAACTTGTTAGCTTCATTGTTGCAGGTGACCCAAATACAGAGGCTACAATAAAATATATGAAGGCTCTGGC
AAAGTATTCCGATATTATAGAGTTAGGAATACCATTTAGCGACCCGATGGCTGATGGAAGTGCAATACAACAGGCCGACA
TTAGGGCATTAAATAATGGAATGAAAGTTTCGAAGGTATTTGATATAATAAAAGAATTTAGAAAAACCAACTCCACCCCA
ATTGTGGTAATGACATACTACAACCCGGTTTATTTTAGAGGAGTTGAAAACTTTATAAAATCACTTAAAGAAGCGGGAGG
AGATGGGCTTATTGTGGTAGATTTACCAGTTGAAGATGCAACAGATTATTTAAATATATGTAAAAAATACAATATTAAAA
CAGTTTTCCTTGGAGCTCCGAATACAACAGAGGAGAGACTAAAAAAGATTGATGATGCAAGTTCATTATTTGTATATCTT
GTATCTGTTTATGGAACAACAGGAACTAGGGAGGGAGTTTCAGAAGAAGCTTTAAACTTTTTGAAAAATACAAAAAAAGT
ATGTAAAAACCCGATTTATGTTGGATTTGGAATTTCTAAAAAGGAACATGTTGAATCGTTTGTAAATAATGGTGCCGATG
GAGTTATTGTAGGTAGTGCCTATGTAAAAATAATAGAAGAGTTCGGAGATTCAGAAGAAACTATAAAAAGGCTTGAAGCG
AAAGCTAAGGAATTAAAAGAAGGCACTAAATAA

Upstream 100 bases:

>100_bases
CGGCAATGCAGAACATACCATATCAATTATAGTTTATTAAATTATATTATTAATCATATTATTAAATTTTATATAAAATA
AATATATAACGAGGGATATA

Downstream 100 bases:

>100_bases
TTGGTTTCATTATTAAAATAGTGATGACAATAATAACAAAAATAACATATGCAAAATAGAGAGATATTTTATGAAAACTC
TAAAAAATAGCTCTGTTCCC

Product: tryptophan synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MDKKLVSFIVAGDPNTEATIKYMKALAKYSDIIELGIPFSDPMADGSAIQQADIRALNNGMKVSKVFDIIKEFRKTNSTP
IVVMTYYNPVYFRGVENFIKSLKEAGGDGLIVVDLPVEDATDYLNICKKYNIKTVFLGAPNTTEERLKKIDDASSLFVYL
VSVYGTTGTREGVSEEALNFLKNTKKVCKNPIYVGFGISKKEHVESFVNNGADGVIVGSAYVKIIEEFGDSEETIKRLEA
KAKELKEGTK

Sequences:

>Translated_250_residues
MDKKLVSFIVAGDPNTEATIKYMKALAKYSDIIELGIPFSDPMADGSAIQQADIRALNNGMKVSKVFDIIKEFRKTNSTP
IVVMTYYNPVYFRGVENFIKSLKEAGGDGLIVVDLPVEDATDYLNICKKYNIKTVFLGAPNTTEERLKKIDDASSLFVYL
VSVYGTTGTREGVSEEALNFLKNTKKVCKNPIYVGFGISKKEHVESFVNNGADGVIVGSAYVKIIEEFGDSEETIKRLEA
KAKELKEGTK
>Mature_250_residues
MDKKLVSFIVAGDPNTEATIKYMKALAKYSDIIELGIPFSDPMADGSAIQQADIRALNNGMKVSKVFDIIKEFRKTNSTP
IVVMTYYNPVYFRGVENFIKSLKEAGGDGLIVVDLPVEDATDYLNICKKYNIKTVFLGAPNTTEERLKKIDDASSLFVYL
VSVYGTTGTREGVSEEALNFLKNTKKVCKNPIYVGFGISKKEHVESFVNNGADGVIVGSAYVKIIEEFGDSEETIKRLEA
KAKELKEGTK

Specific function: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate [H]

COG id: COG0159

COG function: function code E; Tryptophan synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpA family [H]

Homologues:

Organism=Escherichia coli, GI1787514, Length=249, Percent_Identity=32.1285140562249, Blast_Score=138, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6321412, Length=247, Percent_Identity=40.080971659919, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: 280 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR018204
- InterPro:   IPR002028 [H]

Pfam domain/function: PF00290 Trp_syntA [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 27626; Mature: 27626

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00167 TRP_SYNTHASE_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKLVSFIVAGDPNTEATIKYMKALAKYSDIIELGIPFSDPMADGSAIQQADIRALNNG
CCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
MKVSKVFDIIKEFRKTNSTPIVVMTYYNPVYFRGVENFIKSLKEAGGDGLIVVDLPVEDA
CHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHH
TDYLNICKKYNIKTVFLGAPNTTEERLKKIDDASSLFVYLVSVYGTTGTREGVSEEALNF
HHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LKNTKKVCKNPIYVGFGISKKEHVESFVNNGADGVIVGSAYVKIIEEFGDSEETIKRLEA
HHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHH
KAKELKEGTK
HHHHHHCCCC
>Mature Secondary Structure
MDKKLVSFIVAGDPNTEATIKYMKALAKYSDIIELGIPFSDPMADGSAIQQADIRALNNG
CCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
MKVSKVFDIIKEFRKTNSTPIVVMTYYNPVYFRGVENFIKSLKEAGGDGLIVVDLPVEDA
CHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHH
TDYLNICKKYNIKTVFLGAPNTTEERLKKIDDASSLFVYLVSVYGTTGTREGVSEEALNF
HHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LKNTKKVCKNPIYVGFGISKKEHVESFVNNGADGVIVGSAYVKIIEEFGDSEETIKRLEA
HHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHH
KAKELKEGTK
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA