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The map label for this gene is yrbE [H]

Identifier: 150008214

GI number: 150008214

Start: 1852072

End: 1854189

Strand: Reverse

Name: yrbE [H]

Synonym: BDI_1580

Alternate gene names: 150008214

Gene position: 1854189-1852072 (Counterclockwise)

Preceding gene: 150008215

Following gene: 150008213

Centisome position: 38.54

GC content: 50.0

Gene sequence:

>2118_bases
ATGAAACAAATAATTCAAGACCTCAAATCCGGATCAACCATCTTGGAAGAAGTTCCTGTTCCTCAAGTAAAATCCGGCTA
TGTTTTAATCCAAACGACTCGTACGCTAGTATCTTTAGGAACGGAGCGTATGCTCGTGGAGTTCGGAAAGGCGAACCTGA
TTGATAAGGCACGGCAACAACCGGATAAGGTGAAGCAAGTTTTGGACAAGATAAAGACGGATGGTTTACAACCGACACTG
GAGGCCGTGTTCAATAAGCTAGGGCAGCCTTTGCCTTTGGGATATTGCAATGTCGGACGTGTAGTAGCAGTCGGGAAAGG
TGTTGCGGAATTCAAGGTGGGCGATCGGGTGGCCTCGAACGGGAACCATGCGGAGTTTGTTTGTGTGCCGAAGAATCTGG
TGGCGAAGGTGCCGGATGATATAACGGATGAGGAAGCGGCCTTTACGGTGATTGGCTCGATTGGTTTGCAGGGAATCCGC
TTGCTGAATCCTCAGTTGGGAGAGACGGTTGTGGTGGTCGGTCTGGGATTGATCGGTCTGGTGGCGGCGCAGTTGTTGAG
AGCGAACGGCTGTAAGGTTATCGGGGTGGATTTTGACCAGCAGAAGGTGGATATGGCCGCCTCGAAGGGAATCGTGGCTG
TTAATCCGGGCAGAGGTACGGATCCGGTAAGGTTCGTGGAGGATTATACGGGGGGTATCGGTGCGGATGGTGTCTTGATC
ACGGCCTCCACGCAAAACCATGAGGTGATCCATCAAGCGAGTGAGATGTCCCGTAAGAGGGGACGGATCGTTTTGGTGGG
TGTTGTCGGATTGAATATGCGAAGGGATGACTTCTATAAGAAGGAGTTGAGTTTTCAGGTATCTTGCTCGTATGGGGCCG
GACGTTATGACGAGGAATATGAGAACAAGGGGCACGATTATCCGTTGGCTTATGTCCGCTGGACGGAAAAGCGTAATTTT
GAGACGATACTCCACGCGATCTCTTCCGGATCGTTGGATGTCAAGTCGTTGATAACGGAAGAGGTGGACTTGGCCGATTA
TGAGGAGATTTACGGCGATATGCGTAAGAAAGGATCGATCGCTTCCATATTACGTTTTCCCGCTGATTCGAAGATGGAGT
CAGTTGTCTCTATCGGCAGTAATGCCTTTGTGAGTGGAAATGGCAAGATCGGGATTATTGGGGCGGGTAATTATACCTCC
GCCATGATCATACCTTGCTTGGCTAAGGCCCATGCTAGAATCAAGTATATAGCGAGCGCCCAAGGATTGTCCGCCAAGAT
ATTGGCGAGGAAGGCGGGGGCGGAGAACGCCACGTCGGACTATCAAAATATATTGAAAGATCCGGAGGTGGATTTGGTGA
TGGTCACGACACGCCATAACCTGCATGCCCGGATGGTGATAGAGGCTTTACGGAATGGGAAAAGCGTATTCGTGGAGAAA
CCGTTATGCTTGAATGAGACGGAATTGGATGATATCATACGGGCTTATCAAGGGGCTCCTGAGGGCACGACCTTGACGGT
TGGTTTTAACCGGCGTTTCTCTCCGTTCGCCGAGAAGATGAGGCGATTGCTAGGTGACGGACCTAAAAATATAGTGGCGA
CGATGAACGCCGGATTTATCCCGCGGGAAGTGTGGGTGCATGATCTTGAGATAGGTGGAGGGCGGATCATTGGAGAGGCT
TGCCATTTTATCGATCTATGTTCCTTCTTGGCGGGCTCGGAGGTCGTGGCGGTCTGCATGAATGCGTTAGGCGAAAATCC
GGAGGAGAATACGGATAATGCCAGCATATTGCTTCGTTACGCGAATGGGACGAACGCCGTGATCAATTACTTTGCGAACG
GCTCGAAATCGTACGCCAAGGAACGTGTGGAGGTTTTTTCTCAGGAGAGGGTCTTGGTCTTGGATAACTGGCGTAAATTG
ACCGGGTATGGTTTTAAGGGTTTCTCATCGATGAAGGCCGGTATGGATAAAGGGCAAAAACGTCAATTTACGTTGTTGAA
TGAACGTATCCGGGAGGGCGGTGAGCCATTGATTCCATTTGAGAGTATATTGAATACGACGAAAGCTACTTTCGCTTGCA
TTACGAGCTTGAAAGAGAGATGTTGGGTGAATCTCTAA

Upstream 100 bases:

>100_bases
AAGTGTTGAAAATCTATAAGAAGGATAAATATGAGACTATAGATTTTAGAGAAAATGTACCTGATGTTGTAAATGAAATA
TTGAAAATATATAATTCTTT

Downstream 100 bases:

>100_bases
AATTATATATTTCTACTCTTCGGAACTTGAGATCTCGCCAAGTTCGTTATCAAGTCTGGTATAGGCTACGGGCATATATT
AGGAAATACAGGAGCTTTCG

Product: putative zinc-binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 705

Protein sequence:

>705_residues
MKQIIQDLKSGSTILEEVPVPQVKSGYVLIQTTRTLVSLGTERMLVEFGKANLIDKARQQPDKVKQVLDKIKTDGLQPTL
EAVFNKLGQPLPLGYCNVGRVVAVGKGVAEFKVGDRVASNGNHAEFVCVPKNLVAKVPDDITDEEAAFTVIGSIGLQGIR
LLNPQLGETVVVVGLGLIGLVAAQLLRANGCKVIGVDFDQQKVDMAASKGIVAVNPGRGTDPVRFVEDYTGGIGADGVLI
TASTQNHEVIHQASEMSRKRGRIVLVGVVGLNMRRDDFYKKELSFQVSCSYGAGRYDEEYENKGHDYPLAYVRWTEKRNF
ETILHAISSGSLDVKSLITEEVDLADYEEIYGDMRKKGSIASILRFPADSKMESVVSIGSNAFVSGNGKIGIIGAGNYTS
AMIIPCLAKAHARIKYIASAQGLSAKILARKAGAENATSDYQNILKDPEVDLVMVTTRHNLHARMVIEALRNGKSVFVEK
PLCLNETELDDIIRAYQGAPEGTTLTVGFNRRFSPFAEKMRRLLGDGPKNIVATMNAGFIPREVWVHDLEIGGGRIIGEA
CHFIDLCSFLAGSEVVAVCMNALGENPEENTDNASILLRYANGTNAVINYFANGSKSYAKERVEVFSQERVLVLDNWRKL
TGYGFKGFSSMKAGMDKGQKRQFTLLNERIREGGEPLIPFESILNTTKATFACITSLKERCWVNL

Sequences:

>Translated_705_residues
MKQIIQDLKSGSTILEEVPVPQVKSGYVLIQTTRTLVSLGTERMLVEFGKANLIDKARQQPDKVKQVLDKIKTDGLQPTL
EAVFNKLGQPLPLGYCNVGRVVAVGKGVAEFKVGDRVASNGNHAEFVCVPKNLVAKVPDDITDEEAAFTVIGSIGLQGIR
LLNPQLGETVVVVGLGLIGLVAAQLLRANGCKVIGVDFDQQKVDMAASKGIVAVNPGRGTDPVRFVEDYTGGIGADGVLI
TASTQNHEVIHQASEMSRKRGRIVLVGVVGLNMRRDDFYKKELSFQVSCSYGAGRYDEEYENKGHDYPLAYVRWTEKRNF
ETILHAISSGSLDVKSLITEEVDLADYEEIYGDMRKKGSIASILRFPADSKMESVVSIGSNAFVSGNGKIGIIGAGNYTS
AMIIPCLAKAHARIKYIASAQGLSAKILARKAGAENATSDYQNILKDPEVDLVMVTTRHNLHARMVIEALRNGKSVFVEK
PLCLNETELDDIIRAYQGAPEGTTLTVGFNRRFSPFAEKMRRLLGDGPKNIVATMNAGFIPREVWVHDLEIGGGRIIGEA
CHFIDLCSFLAGSEVVAVCMNALGENPEENTDNASILLRYANGTNAVINYFANGSKSYAKERVEVFSQERVLVLDNWRKL
TGYGFKGFSSMKAGMDKGQKRQFTLLNERIREGGEPLIPFESILNTTKATFACITSLKERCWVNL
>Mature_705_residues
MKQIIQDLKSGSTILEEVPVPQVKSGYVLIQTTRTLVSLGTERMLVEFGKANLIDKARQQPDKVKQVLDKIKTDGLQPTL
EAVFNKLGQPLPLGYCNVGRVVAVGKGVAEFKVGDRVASNGNHAEFVCVPKNLVAKVPDDITDEEAAFTVIGSIGLQGIR
LLNPQLGETVVVVGLGLIGLVAAQLLRANGCKVIGVDFDQQKVDMAASKGIVAVNPGRGTDPVRFVEDYTGGIGADGVLI
TASTQNHEVIHQASEMSRKRGRIVLVGVVGLNMRRDDFYKKELSFQVSCSYGAGRYDEEYENKGHDYPLAYVRWTEKRNF
ETILHAISSGSLDVKSLITEEVDLADYEEIYGDMRKKGSIASILRFPADSKMESVVSIGSNAFVSGNGKIGIIGAGNYTS
AMIIPCLAKAHARIKYIASAQGLSAKILARKAGAENATSDYQNILKDPEVDLVMVTTRHNLHARMVIEALRNGKSVFVEK
PLCLNETELDDIIRAYQGAPEGTTLTVGFNRRFSPFAEKMRRLLGDGPKNIVATMNAGFIPREVWVHDLEIGGGRIIGEA
CHFIDLCSFLAGSEVVAVCMNALGENPEENTDNASILLRYANGTNAVINYFANGSKSYAKERVEVFSQERVLVLDNWRKL
TGYGFKGFSSMKAGMDKGQKRQFTLLNERIREGGEPLIPFESILNTTKATFACITSLKERCWVNL

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1788073, Length=300, Percent_Identity=25.6666666666667, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: NA

Molecular weight: Translated: 76981; Mature: 76981

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIIQDLKSGSTILEEVPVPQVKSGYVLIQTTRTLVSLGTERMLVEFGKANLIDKARQQ
CHHHHHHHHCCCHHHHHCCCCCCCCCEEEEEEHHHHHHHCHHHHHHHHCCCHHHHHHHCC
PDKVKQVLDKIKTDGLQPTLEAVFNKLGQPLPLGYCNVGRVVAVGKGVAEFKVGDRVASN
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHCCCCHHHCC
GNHAEFVCVPKNLVAKVPDDITDEEAAFTVIGSIGLQGIRLLNPQLGETVVVVGLGLIGL
CCCEEEEEECHHHHHHCCCCCCCCHHHHHEEEHHCCCCEEECCCCCCCCHHHHHHHHHHH
VAAQLLRANGCKVIGVDFDQQKVDMAASKGIVAVNPGRGTDPVRFVEDYTGGIGADGVLI
HHHHHHHCCCCEEEEECCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCCCCCCCEEE
TASTQNHEVIHQASEMSRKRGRIVLVGVVGLNMRRDDFYKKELSFQVSCSYGAGRYDEEY
EECCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCCEEEEECCCCCCCCHHH
ENKGHDYPLAYVRWTEKRNFETILHAISSGSLDVKSLITEEVDLADYEEIYGDMRKKGSI
HCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCH
ASILRFPADSKMESVVSIGSNAFVSGNGKIGIIGAGNYTSAMIIPCLAKAHARIKYIASA
HHHHHCCCCHHHHHHHHCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHEEEEECC
QGLSAKILARKAGAENATSDYQNILKDPEVDLVMVTTRHNLHARMVIEALRNGKSVFVEK
CCCCHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEC
PLCLNETELDDIIRAYQGAPEGTTLTVGFNRRFSPFAEKMRRLLGDGPKNIVATMNAGFI
CCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEECCCCCC
PREVWVHDLEIGGGRIIGEACHFIDLCSFLAGSEVVAVCMNALGENPEENTDNASILLRY
CHHHEEEEEECCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEE
ANGTNAVINYFANGSKSYAKERVEVFSQERVLVLDNWRKLTGYGFKGFSSMKAGMDKGQK
ECCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCEECCCCCCCCHHHHHHHCCCCCC
RQFTLLNERIREGGEPLIPFESILNTTKATFACITSLKERCWVNL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKQIIQDLKSGSTILEEVPVPQVKSGYVLIQTTRTLVSLGTERMLVEFGKANLIDKARQQ
CHHHHHHHHCCCHHHHHCCCCCCCCCEEEEEEHHHHHHHCHHHHHHHHCCCHHHHHHHCC
PDKVKQVLDKIKTDGLQPTLEAVFNKLGQPLPLGYCNVGRVVAVGKGVAEFKVGDRVASN
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHCCCCHHHCC
GNHAEFVCVPKNLVAKVPDDITDEEAAFTVIGSIGLQGIRLLNPQLGETVVVVGLGLIGL
CCCEEEEEECHHHHHHCCCCCCCCHHHHHEEEHHCCCCEEECCCCCCCCHHHHHHHHHHH
VAAQLLRANGCKVIGVDFDQQKVDMAASKGIVAVNPGRGTDPVRFVEDYTGGIGADGVLI
HHHHHHHCCCCEEEEECCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCCCCCCCEEE
TASTQNHEVIHQASEMSRKRGRIVLVGVVGLNMRRDDFYKKELSFQVSCSYGAGRYDEEY
EECCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCCEEEEECCCCCCCCHHH
ENKGHDYPLAYVRWTEKRNFETILHAISSGSLDVKSLITEEVDLADYEEIYGDMRKKGSI
HCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCH
ASILRFPADSKMESVVSIGSNAFVSGNGKIGIIGAGNYTSAMIIPCLAKAHARIKYIASA
HHHHHCCCCHHHHHHHHCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHEEEEECC
QGLSAKILARKAGAENATSDYQNILKDPEVDLVMVTTRHNLHARMVIEALRNGKSVFVEK
CCCCHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEC
PLCLNETELDDIIRAYQGAPEGTTLTVGFNRRFSPFAEKMRRLLGDGPKNIVATMNAGFI
CCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEECCCCCC
PREVWVHDLEIGGGRIIGEACHFIDLCSFLAGSEVVAVCMNALGENPEENTDNASILLRY
CHHHEEEEEECCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEE
ANGTNAVINYFANGSKSYAKERVEVFSQERVLVLDNWRKLTGYGFKGFSSMKAGMDKGQK
ECCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCEECCCCCCCCHHHHHHHCCCCCC
RQFTLLNERIREGGEPLIPFESILNTTKATFACITSLKERCWVNL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]