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The map label for this gene is bga [H]

Identifier: 150008152

GI number: 150008152

Start: 1775003

End: 1777309

Strand: Reverse

Name: bga [H]

Synonym: BDI_1518

Alternate gene names: 150008152

Gene position: 1777309-1775003 (Counterclockwise)

Preceding gene: 150008153

Following gene: 150008151

Centisome position: 36.94

GC content: 53.19

Gene sequence:

>2307_bases
ATGGATTCCATGAAAAAGAAAATCGCCTATCTATTGCTCCTTTTGATGCTGATACCTGTCGGCTCGTTCGCCAAGGAGAA
ACGTACGTTCGAGATCAAGGACGGTCATTTTTATGTAAACGGGAAGGTAACCCCGATCCTCTCGGGTGAGATGCATTACC
CTCGTATCCCTCATCAATATTGGCGGCATCGCCTTCGGATGATGCGAGCGATGGGCTTGAATACGGTCGCTACCTATGTC
TTCTGGAACCTGCACGAGACGGAGCCGGGTAAATGGGATTTCGAGGGAGACAAGAATCTGGCCGAGTATATCCGGATAGC
GGGAGAGGAGGGATTGATGGTGATCCTCCGTCCCGGCCCGTACGTATGCGCCGAGTGGGAGTTCGGTGGTTATCCGTGGT
GGTTGCAGAATATACCGGGCATGGAGATCCGCCGGGATAACCCGGAGTTCTTGAAACGCACGAAGCTTTATATCGATAAG
CTTTACGAGCAGGTCGGCGACTTGCAGGTGTCGAAAGGCGGCCCTATCATCATGGTGCAGGCCGAGAACGAGTTCGGCTC
TTACGTGGCGCAACGTAAGGATATCCCCTTGGAGGAGCATCGCCGCTACAACGCCAAGATCAAGCGGCAATTGGCGGACG
CCGGTTTCAACGTGCCTCTGTTCACCTCGGACGGAAGCTGGTTGTTCGAGGGCGGTTCCACCCCGGGAGCGTTGCCTACG
GCGAACGGGGAGAGCAACGTGGAGAACTTGAAAAAGGTGGTGAACGAGTATCACGGGGGAGTAGGCCCGTATATGGTAGC
CGAGTTTTATCCCGGTTGGCTGATGCACTGGGCGGAACCATTCCCCGATATAAGCGATTCCGGCATAGCGAGGCAGACGG
AGACGTACCTCCAAAACGATGTCTCTTTCAATTTCTATATGGTTCATGGCGGTACGAATTTCGGTTTCACCAGTGGCGCC
AATTACGACAAGAAGCATGATATCCAGCCGGACTTGACCAGCTACGACTACGACGCCCCGATCAGCGAGGCGGGTTGGGT
GACCCCGAAGTTCGACTCGATCCGCAACGTGATCCGGAAATACGTCACTTATGACGTCCCCGAGGCCCCAGCCCCTATAC
CGCTGATCGAGATCCCGTCGATCTCCTTGACGAAGGTAGCCGATGTGTTGGCCTTGGCGAAAGAAGGGGAACCAGTAGCG
TCTCCGACACCTCTCACGTTCGAGCAATTGAACCAAGGATACGGCTACGTCTTGTACTCTACCCATTTCAACCAACCCCT
GAAAGGCCGTTTGGAGATACCGGGCTTGCGTGATTACGCTACGATCTACGTGGATGGCGAGCGTGTCGGCGAGTTAAACC
GTTGCTTCAACCAATATGCGATGGAAATCGATATCCCGTTCAACGCTACCTTGGACATCTTGGTGGAGAACATGGGGCGT
ATCAATTATGGCGAGGAGATCGTACGCAATACGAAGGGGATCATCAGCTCGGTCAAGATTAACGGCAGCGAGATATCGGA
CTGGAAGATGTACAAGCTCCCGATGGACCGGATGCCGGCTTTGGTCTCCGGCGAACCTTATGTCTATAAGAATGGCTCGC
CCGAGGTAGCGGCGTTGGGGAATAAGCCGGTTCTCTACGAGGGAACCTTCCACCTGTCCGATACCGGCGATACGTTCATC
GACATGGAGGATTGGGGAAAGGGCATTATTTTCATCAATGGCGTCAATATCGGCCGCTATTGGTATGCCGGCCCTCAGCA
AACGCTTTACATACCGGGCGTATGGCTGAACAAAGGAGAGAATAAGATCGTTATTTATGAGCAGCTGAATAATGACCGGA
AGTCGAGCGTACGGACGGTCAAGACTCCTGTCTTGACAAAACTAAAGAAAATTGCAGCCATGGAGAAAAAGAATCGTTTG
ATGGAAAAAACAGTAAGCCCGTTTAGCGTGGATGAGACGATGCGGCGGATCGAGGAGATTATCAAGTCTCAAGGAGGTTC
CGTGTTCGCCATGTTCGATCATGGGCGAAACGCTAGCGAGGTAGGGATGAAGCTGCCTCCGAATAAGGTGATCGTCTTCG
GCTCACCGAAAGTCGGGACTTTATTGATGCAGCAAGATCCGTCTATCTCTTTGGAGCTGCCGCTACGTATCTCCGTTTGG
GAAGATGCGGACGGCAAGGTTTGGGTCGGTTCCCCGAATCTGGAGACGATCGCCTCCGAATACGGGATGGAAAACAGCGG
CGTCATCGAGAAGATGCAAGAGGCCGTAACGAATATCGTGAGTAAATCGATAGCTGGTAGCCGGTAA

Upstream 100 bases:

>100_bases
AATATATAAGCTAGAGAGGATGTCATTTATTTGGCATCCTCTTTTTATTTACATACATTTGCCACGAGATCTTAAACCTA
AAAATAAATCTTTATAACAC

Downstream 100 bases:

>100_bases
GGCTCATGGATCTAATGCGATAAGAGCTTAGGAGGATGTCGGTAAAACGGCGTCCTCTTTTCTTTTATATGGCCCAAGAG
ACTCATTTACCGTGCTGTAG

Product: beta-glycosidase

Products: NA

Alternate protein names: Lactase [H]

Number of amino acids: Translated: 768; Mature: 768

Protein sequence:

>768_residues
MDSMKKKIAYLLLLLMLIPVGSFAKEKRTFEIKDGHFYVNGKVTPILSGEMHYPRIPHQYWRHRLRMMRAMGLNTVATYV
FWNLHETEPGKWDFEGDKNLAEYIRIAGEEGLMVILRPGPYVCAEWEFGGYPWWLQNIPGMEIRRDNPEFLKRTKLYIDK
LYEQVGDLQVSKGGPIIMVQAENEFGSYVAQRKDIPLEEHRRYNAKIKRQLADAGFNVPLFTSDGSWLFEGGSTPGALPT
ANGESNVENLKKVVNEYHGGVGPYMVAEFYPGWLMHWAEPFPDISDSGIARQTETYLQNDVSFNFYMVHGGTNFGFTSGA
NYDKKHDIQPDLTSYDYDAPISEAGWVTPKFDSIRNVIRKYVTYDVPEAPAPIPLIEIPSISLTKVADVLALAKEGEPVA
SPTPLTFEQLNQGYGYVLYSTHFNQPLKGRLEIPGLRDYATIYVDGERVGELNRCFNQYAMEIDIPFNATLDILVENMGR
INYGEEIVRNTKGIISSVKINGSEISDWKMYKLPMDRMPALVSGEPYVYKNGSPEVAALGNKPVLYEGTFHLSDTGDTFI
DMEDWGKGIIFINGVNIGRYWYAGPQQTLYIPGVWLNKGENKIVIYEQLNNDRKSSVRTVKTPVLTKLKKIAAMEKKNRL
MEKTVSPFSVDETMRRIEEIIKSQGGSVFAMFDHGRNASEVGMKLPPNKVIVFGSPKVGTLLMQQDPSISLELPLRISVW
EDADGKVWVGSPNLETIASEYGMENSGVIEKMQEAVTNIVSKSIAGSR

Sequences:

>Translated_768_residues
MDSMKKKIAYLLLLLMLIPVGSFAKEKRTFEIKDGHFYVNGKVTPILSGEMHYPRIPHQYWRHRLRMMRAMGLNTVATYV
FWNLHETEPGKWDFEGDKNLAEYIRIAGEEGLMVILRPGPYVCAEWEFGGYPWWLQNIPGMEIRRDNPEFLKRTKLYIDK
LYEQVGDLQVSKGGPIIMVQAENEFGSYVAQRKDIPLEEHRRYNAKIKRQLADAGFNVPLFTSDGSWLFEGGSTPGALPT
ANGESNVENLKKVVNEYHGGVGPYMVAEFYPGWLMHWAEPFPDISDSGIARQTETYLQNDVSFNFYMVHGGTNFGFTSGA
NYDKKHDIQPDLTSYDYDAPISEAGWVTPKFDSIRNVIRKYVTYDVPEAPAPIPLIEIPSISLTKVADVLALAKEGEPVA
SPTPLTFEQLNQGYGYVLYSTHFNQPLKGRLEIPGLRDYATIYVDGERVGELNRCFNQYAMEIDIPFNATLDILVENMGR
INYGEEIVRNTKGIISSVKINGSEISDWKMYKLPMDRMPALVSGEPYVYKNGSPEVAALGNKPVLYEGTFHLSDTGDTFI
DMEDWGKGIIFINGVNIGRYWYAGPQQTLYIPGVWLNKGENKIVIYEQLNNDRKSSVRTVKTPVLTKLKKIAAMEKKNRL
MEKTVSPFSVDETMRRIEEIIKSQGGSVFAMFDHGRNASEVGMKLPPNKVIVFGSPKVGTLLMQQDPSISLELPLRISVW
EDADGKVWVGSPNLETIASEYGMENSGVIEKMQEAVTNIVSKSIAGSR
>Mature_768_residues
MDSMKKKIAYLLLLLMLIPVGSFAKEKRTFEIKDGHFYVNGKVTPILSGEMHYPRIPHQYWRHRLRMMRAMGLNTVATYV
FWNLHETEPGKWDFEGDKNLAEYIRIAGEEGLMVILRPGPYVCAEWEFGGYPWWLQNIPGMEIRRDNPEFLKRTKLYIDK
LYEQVGDLQVSKGGPIIMVQAENEFGSYVAQRKDIPLEEHRRYNAKIKRQLADAGFNVPLFTSDGSWLFEGGSTPGALPT
ANGESNVENLKKVVNEYHGGVGPYMVAEFYPGWLMHWAEPFPDISDSGIARQTETYLQNDVSFNFYMVHGGTNFGFTSGA
NYDKKHDIQPDLTSYDYDAPISEAGWVTPKFDSIRNVIRKYVTYDVPEAPAPIPLIEIPSISLTKVADVLALAKEGEPVA
SPTPLTFEQLNQGYGYVLYSTHFNQPLKGRLEIPGLRDYATIYVDGERVGELNRCFNQYAMEIDIPFNATLDILVENMGR
INYGEEIVRNTKGIISSVKINGSEISDWKMYKLPMDRMPALVSGEPYVYKNGSPEVAALGNKPVLYEGTFHLSDTGDTFI
DMEDWGKGIIFINGVNIGRYWYAGPQQTLYIPGVWLNKGENKIVIYEQLNNDRKSSVRTVKTPVLTKLKKIAAMEKKNRL
MEKTVSPFSVDETMRRIEEIIKSQGGSVFAMFDHGRNASEVGMKLPPNKVIVFGSPKVGTLLMQQDPSISLELPLRISVW
EDADGKVWVGSPNLETIASEYGMENSGVIEKMQEAVTNIVSKSIAGSR

Specific function: Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages [H]

COG id: COG1874

COG function: function code G; Beta-galactosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 35 family [H]

Homologues:

Organism=Homo sapiens, GI31543093, Length=599, Percent_Identity=37.3956594323873, Blast_Score=355, Evalue=1e-97,
Organism=Homo sapiens, GI119372308, Length=611, Percent_Identity=37.152209492635, Blast_Score=340, Evalue=4e-93,
Organism=Homo sapiens, GI119372312, Length=599, Percent_Identity=37.228714524207, Blast_Score=338, Evalue=1e-92,
Organism=Homo sapiens, GI164519026, Length=603, Percent_Identity=34.9917081260365, Blast_Score=335, Evalue=9e-92,
Organism=Homo sapiens, GI40255043, Length=642, Percent_Identity=34.8909657320872, Blast_Score=324, Evalue=2e-88,
Organism=Homo sapiens, GI208022658, Length=371, Percent_Identity=38.2749326145553, Blast_Score=197, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI72000600, Length=602, Percent_Identity=34.7176079734219, Blast_Score=308, Evalue=6e-84,
Organism=Caenorhabditis elegans, GI17568491, Length=641, Percent_Identity=32.1372854914197, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24646169, Length=621, Percent_Identity=36.5539452495974, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24582088, Length=621, Percent_Identity=35.1046698872786, Blast_Score=328, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR019801
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR001944 [H]

Pfam domain/function: PF01301 Glyco_hydro_35 [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 86713; Mature: 86713

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS01182 GLYCOSYL_HYDROL_F35

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSMKKKIAYLLLLLMLIPVGSFAKEKRTFEIKDGHFYVNGKVTPILSGEMHYPRIPHQY
CCHHHHHHHHHHHHHHHHCCCCCHHCCCEEEEECCEEEECCEEEEEECCCCCCCCCCHHH
WRHRLRMMRAMGLNTVATYVFWNLHETEPGKWDFEGDKNLAEYIRIAGEEGLMVILRPGP
HHHHHHHHHHHCCHHEEEEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCC
YVCAEWEFGGYPWWLQNIPGMEIRRDNPEFLKRTKLYIDKLYEQVGDLQVSKGGPIIMVQ
EEEEECCCCCCCHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEE
AENEFGSYVAQRKDIPLEEHRRYNAKIKRQLADAGFNVPLFTSDGSWLFEGGSTPGALPT
ECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCC
ANGESNVENLKKVVNEYHGGVGPYMVAEFYPGWLMHWAEPFPDISDSGIARQTETYLQND
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
VSFNFYMVHGGTNFGFTSGANYDKKHDIQPDLTSYDYDAPISEAGWVTPKFDSIRNVIRK
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
YVTYDVPEAPAPIPLIEIPSISLTKVADVLALAKEGEPVASPTPLTFEQLNQGYGYVLYS
HHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCEEEEE
THFNQPLKGRLEIPGLRDYATIYVDGERVGELNRCFNQYAMEIDIPFNATLDILVENMGR
ECCCCCCCCCEECCCCCCEEEEEECCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCC
INYGEEIVRNTKGIISSVKINGSEISDWKMYKLPMDRMPALVSGEPYVYKNGSPEVAALG
CCCHHHHHHHHHHCEEEEEECCCCCCCEEEEECCHHHCCCEECCCCEEEECCCCCEEEEC
NKPVLYEGTFHLSDTGDTFIDMEDWGKGIIFINGVNIGRYWYAGPQQTLYIPGVWLNKGE
CCCEEEEEEEEECCCCCEEEEHHHCCCEEEEEEEEEECCEEECCCCCEEEECEEEEECCC
NKIVIYEQLNNDRKSSVRTVKTPVLTKLKKIAAMEKKNRLMEKTVSPFSVDETMRRIEEI
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IKSQGGSVFAMFDHGRNASEVGMKLPPNKVIVFGSPKVGTLLMQQDPSISLELPLRISVW
HHCCCCCEEEEEECCCCHHHCCCCCCCCEEEEECCCCCCEEEEECCCCEEEEEEEEEEEE
EDADGKVWVGSPNLETIASEYGMENSGVIEKMQEAVTNIVSKSIAGSR
ECCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDSMKKKIAYLLLLLMLIPVGSFAKEKRTFEIKDGHFYVNGKVTPILSGEMHYPRIPHQY
CCHHHHHHHHHHHHHHHHCCCCCHHCCCEEEEECCEEEECCEEEEEECCCCCCCCCCHHH
WRHRLRMMRAMGLNTVATYVFWNLHETEPGKWDFEGDKNLAEYIRIAGEEGLMVILRPGP
HHHHHHHHHHHCCHHEEEEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCC
YVCAEWEFGGYPWWLQNIPGMEIRRDNPEFLKRTKLYIDKLYEQVGDLQVSKGGPIIMVQ
EEEEECCCCCCCHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEE
AENEFGSYVAQRKDIPLEEHRRYNAKIKRQLADAGFNVPLFTSDGSWLFEGGSTPGALPT
ECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCC
ANGESNVENLKKVVNEYHGGVGPYMVAEFYPGWLMHWAEPFPDISDSGIARQTETYLQND
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
VSFNFYMVHGGTNFGFTSGANYDKKHDIQPDLTSYDYDAPISEAGWVTPKFDSIRNVIRK
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
YVTYDVPEAPAPIPLIEIPSISLTKVADVLALAKEGEPVASPTPLTFEQLNQGYGYVLYS
HHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCEEEEE
THFNQPLKGRLEIPGLRDYATIYVDGERVGELNRCFNQYAMEIDIPFNATLDILVENMGR
ECCCCCCCCCEECCCCCCEEEEEECCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCC
INYGEEIVRNTKGIISSVKINGSEISDWKMYKLPMDRMPALVSGEPYVYKNGSPEVAALG
CCCHHHHHHHHHHCEEEEEECCCCCCCEEEEECCHHHCCCEECCCCEEEECCCCCEEEEC
NKPVLYEGTFHLSDTGDTFIDMEDWGKGIIFINGVNIGRYWYAGPQQTLYIPGVWLNKGE
CCCEEEEEEEEECCCCCEEEEHHHCCCEEEEEEEEEECCEEECCCCCEEEECEEEEECCC
NKIVIYEQLNNDRKSSVRTVKTPVLTKLKKIAAMEKKNRLMEKTVSPFSVDETMRRIEEI
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IKSQGGSVFAMFDHGRNASEVGMKLPPNKVIVFGSPKVGTLLMQQDPSISLELPLRISVW
HHCCCCCEEEEEECCCCHHHCCCCCCCCEEEEECCCCCCEEEEECCCCEEEEEEEEEEEE
EDADGKVWVGSPNLETIASEYGMENSGVIEKMQEAVTNIVSKSIAGSR
ECCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8563148 [H]