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The map label for this gene is trxB [H]

Identifier: 150006117

GI number: 150006117

Start: 4492941

End: 4493888

Strand: Direct

Name: trxB [H]

Synonym: BVU_3628

Alternate gene names: 150006117

Gene position: 4492941-4493888 (Clockwise)

Preceding gene: 150006116

Following gene: 150006118

Centisome position: 87.02

GC content: 50.21

Gene sequence:

>948_bases
ATGAGTACAGAAAAAGTTAAATGCCTTATCATCGGCTCAGGTCCTGCCGGCTACACCGCCGCCATTTATACAGGACGTGC
CAACATCGCCCCGGTCTTATATGAAGGTCTACAGCCCGGAGGCCAGTTGACCATCACTACCGAGGTGGAAAATTTCCCCG
GATATCCCGAAGGTATCAGCGGTACCCAACTGATGGAGGACTTGCGCAAACAAGCAGAACGCTTCGGCGCGGATATCCGC
AATGGCATTGCAACCTCCGCCGACCTGAGCAAACGTCCTTACCGTATCACCATTGATGACGAAAAAGTGATTGAGGCAGA
AACTGTAATTATATCCACAGGTGCCACCGCCAAATATCTAGGTCTGGAAGACGAACAGAAATATGCCGGAATGGGTGTAA
GCGCCTGCGCCACCTGCGACGGTTTCTTCTATCGCAAGAAAACCGTAGCTGTAGTAGGTGGCGGTGACACTGCTTGCGAG
GAGGCTGTCTATCTGGCAGGACTGGCCAAACAGGTTTACCTGATTGTACGCAAACCGTTCTTACGCGCATCCAAGATTAT
GCAGGCACGTGTTATGAACCATCCTAACATCAAGGTACTGTTCGAGCACAACGCTGTCGGCTTATACGGAGAGAATGGCG
TAGAAGGTGTTCATTTGGTAAAGCGTCAGGGTGAATGCAACGAAGAACGTTATGACTTGCCTATTGACGGATTCTTTCTG
GCTATCGGCCATAAACCCAATTCAGACATTTTCAAGGATTATTTGGACACAGACGAAGTAGGCTACATTATAACAGAAGC
AGGTACTCCGCGTACGAAGGTTCCCGGTGTGTTCGCTGCCGGTGATGTGGCCGACCCGCATTATCGTCAGGCTATCACTG
CTGCCGGAAGTGGCTGCAAGGCTGCCATAGAAGCAGAAAGATACCTATCTGCCAACGACTTATTATAA

Upstream 100 bases:

>100_bases
CCCAAATGCCGAAGTGATAGACTTACGATAACAAGCAGAGTTCAAGATAGAGAGATAATATAATATTCATCAAATTAAAT
TAAGTAAAGAAATAAGTATT

Downstream 100 bases:

>100_bases
TAAAAACAAACTAACCCCACAACAAACACTATGACACATTTTCTAAGGAAGATGGCAGCTGCCTGGATTATTCTAGGCAG
CGTGTCGGTGGGCTTTGCAC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSTEKVKCLIIGSGPAGYTAAIYTGRANIAPVLYEGLQPGGQLTITTEVENFPGYPEGISGTQLMEDLRKQAERFGADIR
NGIATSADLSKRPYRITIDDEKVIEAETVIISTGATAKYLGLEDEQKYAGMGVSACATCDGFFYRKKTVAVVGGGDTACE
EAVYLAGLAKQVYLIVRKPFLRASKIMQARVMNHPNIKVLFEHNAVGLYGENGVEGVHLVKRQGECNEERYDLPIDGFFL
AIGHKPNSDIFKDYLDTDEVGYIITEAGTPRTKVPGVFAAGDVADPHYRQAITAAGSGCKAAIEAERYLSANDLL

Sequences:

>Translated_315_residues
MSTEKVKCLIIGSGPAGYTAAIYTGRANIAPVLYEGLQPGGQLTITTEVENFPGYPEGISGTQLMEDLRKQAERFGADIR
NGIATSADLSKRPYRITIDDEKVIEAETVIISTGATAKYLGLEDEQKYAGMGVSACATCDGFFYRKKTVAVVGGGDTACE
EAVYLAGLAKQVYLIVRKPFLRASKIMQARVMNHPNIKVLFEHNAVGLYGENGVEGVHLVKRQGECNEERYDLPIDGFFL
AIGHKPNSDIFKDYLDTDEVGYIITEAGTPRTKVPGVFAAGDVADPHYRQAITAAGSGCKAAIEAERYLSANDLL
>Mature_314_residues
STEKVKCLIIGSGPAGYTAAIYTGRANIAPVLYEGLQPGGQLTITTEVENFPGYPEGISGTQLMEDLRKQAERFGADIRN
GIATSADLSKRPYRITIDDEKVIEAETVIISTGATAKYLGLEDEQKYAGMGVSACATCDGFFYRKKTVAVVGGGDTACEE
AVYLAGLAKQVYLIVRKPFLRASKIMQARVMNHPNIKVLFEHNAVGLYGENGVEGVHLVKRQGECNEERYDLPIDGFFLA
IGHKPNSDIFKDYLDTDEVGYIITEAGTPRTKVPGVFAAGDVADPHYRQAITAAGSGCKAAIEAERYLSANDLL

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=316, Percent_Identity=49.0506329113924, Blast_Score=283, Evalue=8e-78,
Organism=Escherichia coli, GI87081763, Length=306, Percent_Identity=31.6993464052288, Blast_Score=131, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=48.2649842271293, Blast_Score=302, Evalue=5e-83,
Organism=Saccharomyces cerevisiae, GI6320560, Length=315, Percent_Identity=46.3492063492063, Blast_Score=291, Evalue=7e-80,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34004; Mature: 33873

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEKVKCLIIGSGPAGYTAAIYTGRANIAPVLYEGLQPGGQLTITTEVENFPGYPEGIS
CCCCEEEEEEEECCCCCCEEEEEECCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCC
GTQLMEDLRKQAERFGADIRNGIATSADLSKRPYRITIDDEKVIEAETVIISTGATAKYL
HHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEEECCCCEEEE
GLEDEQKYAGMGVSACATCDGFFYRKKTVAVVGGGDTACEEAVYLAGLAKQVYLIVRKPF
CCCCCHHHCCCCCHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCH
LRASKIMQARVMNHPNIKVLFEHNAVGLYGENGVEGVHLVKRQGECNEERYDLPIDGFFL
HHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCEEE
AIGHKPNSDIFKDYLDTDEVGYIITEAGTPRTKVPGVFAAGDVADPHYRQAITAAGSGCK
EECCCCCHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCC
AAIEAERYLSANDLL
EEHHHHHHCCCCCCC
>Mature Secondary Structure 
STEKVKCLIIGSGPAGYTAAIYTGRANIAPVLYEGLQPGGQLTITTEVENFPGYPEGIS
CCCEEEEEEEECCCCCCEEEEEECCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCC
GTQLMEDLRKQAERFGADIRNGIATSADLSKRPYRITIDDEKVIEAETVIISTGATAKYL
HHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEEECCCCEEEE
GLEDEQKYAGMGVSACATCDGFFYRKKTVAVVGGGDTACEEAVYLAGLAKQVYLIVRKPF
CCCCCHHHCCCCCHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCH
LRASKIMQARVMNHPNIKVLFEHNAVGLYGENGVEGVHLVKRQGECNEERYDLPIDGFFL
HHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCEEE
AIGHKPNSDIFKDYLDTDEVGYIITEAGTPRTKVPGVFAAGDVADPHYRQAITAAGSGCK
EECCCCCHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCC
AAIEAERYLSANDLL
EEHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA