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The map label for this gene is ntrY [H]

Identifier: 150005965

GI number: 150005965

Start: 4309580

End: 4310881

Strand: Direct

Name: ntrY [H]

Synonym: BVU_3463

Alternate gene names: 150005965

Gene position: 4309580-4310881 (Clockwise)

Preceding gene: 150005964

Following gene: 150005966

Centisome position: 83.47

GC content: 48.54

Gene sequence:

>1302_bases
GTGAAACAATTCTTCTTCCGCCTATTTACCGTACTGGTTCTAGCCATTGCCTGCACCTTACTAATCCAGCAGCGCAACTG
GTTGTGGCTATGCGTAATCGTACCTTCATTCCTCGTTTCCATAGGCTGGTTTTACCGCCTGTACACTTTTAATACCCGGA
AGATAGCCTTTCTGCTCGACGCCATCGAAAACGACGACCCCGCTGTTCGTTTTTACGAACATGCCTCCCCTGGCGATTCT
TCCATGGTCAATGTCATGCTGAACCGTATCGCACGTATTTTGTACAATGTAAAACAGGAAACGGCACAACGCGAGAAGTA
TTATGAGCTCATCATGGACTTTGTAGAAACCGGCATAGTGGTACTGAACAGCAAAGGCTCCGTTTATCAAAAGAACAAAG
AGGCCATGAATCTGTTGGGGCTGGATGTTCTGACTCATGTCAAACAACTCTCCCGCATCTCGGACGAACTGATGACTGCT
TTGGAAAAAGCAGTTCCGGGTGACAAGCTGCAAATTCAGTTCAATACGGAACGGGGAACGGTGCATCTTGCCTTACGGGT
GTCCGGCATCCGTATCAAAGACGAGGAACTCCGCATTATTGCCTTGAGTGATATCAATCGGGAATTGGATGAACGGGAAA
TAGATTCATGGATACGCCTTACCCGCGTGCTGACACACGAAATTATGAACTCCCTGACCCCGGTGACTTCCCTCAGCGAA
ACGCTGCTGGCTCTTCCCGGAGCAGAAAATGAAGAAATGAAACAAGGGCTGGAAACGATTCACTCTACAGGTAAAGGATT
GATAAATTTTGTCATGTCTTATCGCAAACTGACACGACTGCCATCACCTGAGCCATCGCTGTTCTATGTCCGTCCTTTCC
TGGAACGGATGATCCGACTGGCACAGCACCAGCATCCATGCCCCAACATCACCCTTTCCATCCTCGAAGCCCGGGAAGAC
CTGATAGTCTTTGCCGACGAGAACCTGATAGCCCAAGTGGTTACGAATCTGCTGAAAAATGCGATTCAAGCCATAGGTAA
TGCTCCCGACGGAAAGATCACCTTGAAAGCTTATTGTGATCCGCAAGAAAGTATCCGTATAGAGATAGCCAACAACGGTC
CCGCCATTCCTCCCGATGCAGCCGGACAAATTTTTGTACCTTTCTTCACGACCAAAGAGGAAGGAAGCGGCATCGGACTG
AGCCTGAGCAAACAAATCATGAGACTGAGCGGTGGCACACTGACCCTGCTGCCTTACAAGGAAAAGGGACAGGCCACTGT
TTTTGTGCTGGTTTTTAATTAA

Upstream 100 bases:

>100_bases
CATTCTTCACGATGGTTCAGGATGACAAAACAAATAACAATAATCTATTTTTAAACAGGAACTAAAGGAACATTCAAACG
AAATAATAAATAATTAAGCT

Downstream 100 bases:

>100_bases
AAATAAAAATGTACTAATGTGTCAGCCAATTACCATCCGGTACACAGCGCAGCCATTAGCAAATTAGCAAATTATTTAAA
ATGAAACATTCTCCTGAATT

Product: putative two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MKQFFFRLFTVLVLAIACTLLIQQRNWLWLCVIVPSFLVSIGWFYRLYTFNTRKIAFLLDAIENDDPAVRFYEHASPGDS
SMVNVMLNRIARILYNVKQETAQREKYYELIMDFVETGIVVLNSKGSVYQKNKEAMNLLGLDVLTHVKQLSRISDELMTA
LEKAVPGDKLQIQFNTERGTVHLALRVSGIRIKDEELRIIALSDINRELDEREIDSWIRLTRVLTHEIMNSLTPVTSLSE
TLLALPGAENEEMKQGLETIHSTGKGLINFVMSYRKLTRLPSPEPSLFYVRPFLERMIRLAQHQHPCPNITLSILEARED
LIVFADENLIAQVVTNLLKNAIQAIGNAPDGKITLKAYCDPQESIRIEIANNGPAIPPDAAGQIFVPFFTTKEEGSGIGL
SLSKQIMRLSGGTLTLLPYKEKGQATVFVLVFN

Sequences:

>Translated_433_residues
MKQFFFRLFTVLVLAIACTLLIQQRNWLWLCVIVPSFLVSIGWFYRLYTFNTRKIAFLLDAIENDDPAVRFYEHASPGDS
SMVNVMLNRIARILYNVKQETAQREKYYELIMDFVETGIVVLNSKGSVYQKNKEAMNLLGLDVLTHVKQLSRISDELMTA
LEKAVPGDKLQIQFNTERGTVHLALRVSGIRIKDEELRIIALSDINRELDEREIDSWIRLTRVLTHEIMNSLTPVTSLSE
TLLALPGAENEEMKQGLETIHSTGKGLINFVMSYRKLTRLPSPEPSLFYVRPFLERMIRLAQHQHPCPNITLSILEARED
LIVFADENLIAQVVTNLLKNAIQAIGNAPDGKITLKAYCDPQESIRIEIANNGPAIPPDAAGQIFVPFFTTKEEGSGIGL
SLSKQIMRLSGGTLTLLPYKEKGQATVFVLVFN
>Mature_433_residues
MKQFFFRLFTVLVLAIACTLLIQQRNWLWLCVIVPSFLVSIGWFYRLYTFNTRKIAFLLDAIENDDPAVRFYEHASPGDS
SMVNVMLNRIARILYNVKQETAQREKYYELIMDFVETGIVVLNSKGSVYQKNKEAMNLLGLDVLTHVKQLSRISDELMTA
LEKAVPGDKLQIQFNTERGTVHLALRVSGIRIKDEELRIIALSDINRELDEREIDSWIRLTRVLTHEIMNSLTPVTSLSE
TLLALPGAENEEMKQGLETIHSTGKGLINFVMSYRKLTRLPSPEPSLFYVRPFLERMIRLAQHQHPCPNITLSILEARED
LIVFADENLIAQVVTNLLKNAIQAIGNAPDGKITLKAYCDPQESIRIEIANNGPAIPPDAAGQIFVPFFTTKEEGSGIGL
SLSKQIMRLSGGTLTLLPYKEKGQATVFVLVFN

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=383, Percent_Identity=25.5874673629243, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790436, Length=109, Percent_Identity=36.697247706422, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48985; Mature: 48985

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFFFRLFTVLVLAIACTLLIQQRNWLWLCVIVPSFLVSIGWFYRLYTFNTRKIAFLLD
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHEEECCCHHHHHHH
AIENDDPAVRFYEHASPGDSSMVNVMLNRIARILYNVKQETAQREKYYELIMDFVETGIV
HHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
VLNSKGSVYQKNKEAMNLLGLDVLTHVKQLSRISDELMTALEKAVPGDKLQIQFNTERGT
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCE
VHLALRVSGIRIKDEELRIIALSDINRELDEREIDSWIRLTRVLTHEIMNSLTPVTSLSE
EEEEEEEECEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TLLALPGAENEEMKQGLETIHSTGKGLINFVMSYRKLTRLPSPEPSLFYVRPFLERMIRL
HHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHH
AQHQHPCPNITLSILEAREDLIVFADENLIAQVVTNLLKNAIQAIGNAPDGKITLKAYCD
HHCCCCCCCCHHHEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
PQESIRIEIANNGPAIPPDAAGQIFVPFFTTKEEGSGIGLSLSKQIMRLSGGTLTLLPYK
CCCCEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEEC
EKGQATVFVLVFN
CCCCEEEEEEEEC
>Mature Secondary Structure
MKQFFFRLFTVLVLAIACTLLIQQRNWLWLCVIVPSFLVSIGWFYRLYTFNTRKIAFLLD
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHEEECCCHHHHHHH
AIENDDPAVRFYEHASPGDSSMVNVMLNRIARILYNVKQETAQREKYYELIMDFVETGIV
HHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
VLNSKGSVYQKNKEAMNLLGLDVLTHVKQLSRISDELMTALEKAVPGDKLQIQFNTERGT
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCE
VHLALRVSGIRIKDEELRIIALSDINRELDEREIDSWIRLTRVLTHEIMNSLTPVTSLSE
EEEEEEEECEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TLLALPGAENEEMKQGLETIHSTGKGLINFVMSYRKLTRLPSPEPSLFYVRPFLERMIRL
HHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHH
AQHQHPCPNITLSILEAREDLIVFADENLIAQVVTNLLKNAIQAIGNAPDGKITLKAYCD
HHCCCCCCCCHHHEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
PQESIRIEIANNGPAIPPDAAGQIFVPFFTTKEEGSGIGLSLSKQIMRLSGGTLTLLPYK
CCCCEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEEC
EKGQATVFVLVFN
CCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]