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The map label for this gene is zraR [H]

Identifier: 150005964

GI number: 150005964

Start: 4308124

End: 4309464

Strand: Direct

Name: zraR [H]

Synonym: BVU_3462

Alternate gene names: 150005964

Gene position: 4308124-4309464 (Clockwise)

Preceding gene: 150005963

Following gene: 150005965

Centisome position: 83.44

GC content: 47.5

Gene sequence:

>1341_bases
ATGAGCAAACAAGGAACCATCATTGTGATAGATGATAACAAAGGAGTGCTGTCGGCAGTAAAGCTATTGCTGAAAAATCA
TTTCGAACATATCGTCACACTGCCCTCACCCATCACACTGCCCGCTGCGTTACGTGAAGAAAATGCGCAAGTGGTGCTGC
TGGATATGAATTTCAGCAGCGGACTGAATACCGGGAATGAAGGTCTGTACTGGTTACACGAGATAAAGAAAATACACCCC
TCCCTGCCCGTAGTACTTTTCACAGCCTATGCTGACATAGACCTGGCAGTGCGCGGCATCAAGGAAGGAGCGACAGACTT
CATCGTCAAACCCTGGGACAATGCCCGGCTGATAGAAACCTTGCTGTCTGCCTGCCGCAATTCCTCCAAGAACAAGAAGA
GAGCGGAAATCCCTAAAACCGTATCTTCTATGTATTGGGGAGAAAGCAATGCCATGAAGCAACTGCGGACGCTGATAGAG
AAAGTGGCGCAAACGGATGCCAATATTCTGATTACAGGAGAGAACGGCACAGGAAAAGAAATGCTGGCGCGGGAAATACA
CGCCTTGTCCAACCGATACCGGCGGGATATGATAACAGTGGACATGGGTGCCATCACCGAATCCCTGTTCGAAAGCGAAC
TGTTCGGCCATAAAAAAGGCTCGTTTACCGATGCCCATACCGACCGTGCTGGTAAATTTGAAGCCGCCCATGAAGGGACT
TTGTTTCTGGACGAAATAGGCAACCTGCCCTATCACCTGCAATCCAAACTACTCACCGCCATTCAGAGCCGGAGCGTGGT
GCGAGTAGGAAGCAACGAACCGATACCTGTCAACATACGTTTGATTTGCGCCACCAATTGTAATTTGGAAGAGATGGTGG
CCAAAGGCAAATTCCGCGAAGATTTGCTTTACCGCATCAATACCATCCACATCGAGATTCCCCCTCTGCGGGAACGCAAA
GAAGATATTATCCCTTTGGCCGAACGCTTTATAGACCGGTTCTGCAAACAATATGACAAAGGAAATATCCTTCTTTCTAC
CGGTGCGCAAGAAAAGTTACGGACATATCCGTGGTATGGAAACATACGCGAACTGGAACATGCCGTAGAGAAAGCGGTCA
TTATCAATGAAGATGGTATATTGAGTGAGGAACATTTTCATTTTCCCCGAAAAATAGCGGCTCCTGCGACAGAAACAAGT
GTCTCTACACTGGAAGAGATGGAATTGCAAATGATTCAGAAAGCGATAGAGAAATGCAACGGAAACCTCTCGGCTGTAGC
GGCACAGTTGGGAATTACCCGGCAGACGCTTTATAATAAGATGAAAAAATTCGGATTATGA

Upstream 100 bases:

>100_bases
CTATAAAGGAATGGAAATGAGAGTGTGTGAAGAGATAGTACCTTTGCATGAAACGCACAACTAAAGATATCTTTAAAGGA
AAAAGAAGCTACAACGACTT

Downstream 100 bases:

>100_bases
CCTATTATCTCATCTCATTCTTCACGATGGTTCAGGATGACAAAACAAATAACAATAATCTATTTTTAAACAGGAACTAA
AGGAACATTCAAACGAAATA

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSKQGTIIVIDDNKGVLSAVKLLLKNHFEHIVTLPSPITLPAALREENAQVVLLDMNFSSGLNTGNEGLYWLHEIKKIHP
SLPVVLFTAYADIDLAVRGIKEGATDFIVKPWDNARLIETLLSACRNSSKNKKRAEIPKTVSSMYWGESNAMKQLRTLIE
KVAQTDANILITGENGTGKEMLAREIHALSNRYRRDMITVDMGAITESLFESELFGHKKGSFTDAHTDRAGKFEAAHEGT
LFLDEIGNLPYHLQSKLLTAIQSRSVVRVGSNEPIPVNIRLICATNCNLEEMVAKGKFREDLLYRINTIHIEIPPLRERK
EDIIPLAERFIDRFCKQYDKGNILLSTGAQEKLRTYPWYGNIRELEHAVEKAVIINEDGILSEEHFHFPRKIAAPATETS
VSTLEEMELQMIQKAIEKCNGNLSAVAAQLGITRQTLYNKMKKFGL

Sequences:

>Translated_446_residues
MSKQGTIIVIDDNKGVLSAVKLLLKNHFEHIVTLPSPITLPAALREENAQVVLLDMNFSSGLNTGNEGLYWLHEIKKIHP
SLPVVLFTAYADIDLAVRGIKEGATDFIVKPWDNARLIETLLSACRNSSKNKKRAEIPKTVSSMYWGESNAMKQLRTLIE
KVAQTDANILITGENGTGKEMLAREIHALSNRYRRDMITVDMGAITESLFESELFGHKKGSFTDAHTDRAGKFEAAHEGT
LFLDEIGNLPYHLQSKLLTAIQSRSVVRVGSNEPIPVNIRLICATNCNLEEMVAKGKFREDLLYRINTIHIEIPPLRERK
EDIIPLAERFIDRFCKQYDKGNILLSTGAQEKLRTYPWYGNIRELEHAVEKAVIINEDGILSEEHFHFPRKIAAPATETS
VSTLEEMELQMIQKAIEKCNGNLSAVAAQLGITRQTLYNKMKKFGL
>Mature_445_residues
SKQGTIIVIDDNKGVLSAVKLLLKNHFEHIVTLPSPITLPAALREENAQVVLLDMNFSSGLNTGNEGLYWLHEIKKIHPS
LPVVLFTAYADIDLAVRGIKEGATDFIVKPWDNARLIETLLSACRNSSKNKKRAEIPKTVSSMYWGESNAMKQLRTLIEK
VAQTDANILITGENGTGKEMLAREIHALSNRYRRDMITVDMGAITESLFESELFGHKKGSFTDAHTDRAGKFEAAHEGTL
FLDEIGNLPYHLQSKLLTAIQSRSVVRVGSNEPIPVNIRLICATNCNLEEMVAKGKFREDLLYRINTIHIEIPPLRERKE
DIIPLAERFIDRFCKQYDKGNILLSTGAQEKLRTYPWYGNIRELEHAVEKAVIINEDGILSEEHFHFPRKIAAPATETSV
STLEEMELQMIQKAIEKCNGNLSAVAAQLGITRQTLYNKMKKFGL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=443, Percent_Identity=40.6320541760722, Blast_Score=304, Evalue=9e-84,
Organism=Escherichia coli, GI1788550, Length=413, Percent_Identity=39.225181598063, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1790299, Length=476, Percent_Identity=32.3529411764706, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI1788905, Length=449, Percent_Identity=34.075723830735, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI1789233, Length=317, Percent_Identity=42.2712933753943, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI87082117, Length=316, Percent_Identity=40.1898734177215, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1789087, Length=311, Percent_Identity=41.8006430868167, Blast_Score=231, Evalue=7e-62,
Organism=Escherichia coli, GI87082152, Length=315, Percent_Identity=39.6825396825397, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI1786524, Length=336, Percent_Identity=38.3928571428571, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI87081872, Length=316, Percent_Identity=37.0253164556962, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1787583, Length=304, Percent_Identity=33.2236842105263, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI87081858, Length=303, Percent_Identity=30.03300330033, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789828, Length=235, Percent_Identity=35.3191489361702, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50149; Mature: 50018

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQGTIIVIDDNKGVLSAVKLLLKNHFEHIVTLPSPITLPAALREENAQVVLLDMNFSS
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHCCCCEEEEEEECCCC
GLNTGNEGLYWLHEIKKIHPSLPVVLFTAYADIDLAVRGIKEGATDFIVKPWDNARLIET
CCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCEECCCCCHHHHHH
LLSACRNSSKNKKRAEIPKTVSSMYWGESNAMKQLRTLIEKVAQTDANILITGENGTGKE
HHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHH
MLAREIHALSNRYRRDMITVDMGAITESLFESELFGHKKGSFTDAHTDRAGKFEAAHEGT
HHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
LFLDEIGNLPYHLQSKLLTAIQSRSVVRVGSNEPIPVNIRLICATNCNLEEMVAKGKFRE
EEHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEECCCCHHHHHHCCCHHH
DLLYRINTIHIEIPPLRERKEDIIPLAERFIDRFCKQYDKGNILLSTGAQEKLRTYPWYG
HHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCC
NIRELEHAVEKAVIINEDGILSEEHFHFPRKIAAPATETSVSTLEEMELQMIQKAIEKCN
CHHHHHHHHHHEEEECCCCCCCHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GNLSAVAAQLGITRQTLYNKMKKFGL
CCHHHHHHHHCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKQGTIIVIDDNKGVLSAVKLLLKNHFEHIVTLPSPITLPAALREENAQVVLLDMNFSS
CCCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHCCCCEEEEEEECCCC
GLNTGNEGLYWLHEIKKIHPSLPVVLFTAYADIDLAVRGIKEGATDFIVKPWDNARLIET
CCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCEECCCCCHHHHHH
LLSACRNSSKNKKRAEIPKTVSSMYWGESNAMKQLRTLIEKVAQTDANILITGENGTGKE
HHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHH
MLAREIHALSNRYRRDMITVDMGAITESLFESELFGHKKGSFTDAHTDRAGKFEAAHEGT
HHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
LFLDEIGNLPYHLQSKLLTAIQSRSVVRVGSNEPIPVNIRLICATNCNLEEMVAKGKFRE
EEHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEECCCCHHHHHHCCCHHH
DLLYRINTIHIEIPPLRERKEDIIPLAERFIDRFCKQYDKGNILLSTGAQEKLRTYPWYG
HHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCC
NIRELEHAVEKAVIINEDGILSEEHFHFPRKIAAPATETSVSTLEEMELQMIQKAIEKCN
CHHHHHHHHHHEEEECCCCCCCHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GNLSAVAAQLGITRQTLYNKMKKFGL
CCHHHHHHHHCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]