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The map label for this gene is umuD [H]

Identifier: 150005927

GI number: 150005927

Start: 4265569

End: 4266246

Strand: Direct

Name: umuD [H]

Synonym: BVU_3423

Alternate gene names: 150005927

Gene position: 4265569-4266246 (Clockwise)

Preceding gene: 150005926

Following gene: 150005928

Centisome position: 82.62

GC content: 49.71

Gene sequence:

>678_bases
ATGGGTAATCAGGAAAAACAAGTGATAAAACAAGCGGAAAACCAGCCCAAGAAACCCGGTAGAGGAGGTAAAAGACCAGG
TGCAGGTCGCCCCAAGGGTACCAGCAAACTCTATGCTTTCCGGGCCGATAATGAAGTGGCTGCCTATCTGGACAGCCAGG
AGAACAAGACGGACTTTATCAAGGAATGTATCGTCTGGCAGATGGAGGTTGCTAAAAGCAGGCAGGAAGACGAAGCTTTG
ATGCAGTTGGGGGAAGTGATGCCTACCAGCCGTGTCAAACCGATGACGCTGCCTTTCTTTGATGTGAAGGTGGTGGCCGG
TTTCCCCATTCCTTTGAACAACGATGAACTGGCGCAGGACATTGAGGTGTTGAAGATGCTGTGCCCACACCCGGACTCTT
CGTACTTGATCCGAGTGCAAGGCCGTTCGATGATTGAAGCCGGAGTGAATGATGGCGACATCATCATTGTAGATAAGAGT
GAACGGAACCCTACGGAAAAGCAGATTGCGGTCTGCGAACTGAATGGAGAGTACACGCTGAAACGGGTTTGCAAGAAGGA
AGGAATCCTTTGGCTGGTTCCGGCCAATCCCGAGTACCCCGAGATTAAAATCATTGATGGTGATGATTTCAGTGTTTGGG
GAGTCGTGACGTATATCATCCATAAGCCTGTTTACTAA

Upstream 100 bases:

>100_bases
GAAGTCATAAGGATGTTATACGTTTTTCATATGTTTTTTGAAATACGTATAACATTATTCGGAAAACTGCTTATCTTTGT
GCAGAAATAGTGTTTAGACC

Downstream 100 bases:

>100_bases
TTTCTATAATCCGTTTGCCAACAACTCATGATTGCTTTAGTCGATTGCAACAGCTTCTTCTGTTCCGTGGAAAAGGTCTT
CCATCCCGGACTGAACGGAA

Product: putative SOS-response transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MGNQEKQVIKQAENQPKKPGRGGKRPGAGRPKGTSKLYAFRADNEVAAYLDSQENKTDFIKECIVWQMEVAKSRQEDEAL
MQLGEVMPTSRVKPMTLPFFDVKVVAGFPIPLNNDELAQDIEVLKMLCPHPDSSYLIRVQGRSMIEAGVNDGDIIIVDKS
ERNPTEKQIAVCELNGEYTLKRVCKKEGILWLVPANPEYPEIKIIDGDDFSVWGVVTYIIHKPVY

Sequences:

>Translated_225_residues
MGNQEKQVIKQAENQPKKPGRGGKRPGAGRPKGTSKLYAFRADNEVAAYLDSQENKTDFIKECIVWQMEVAKSRQEDEAL
MQLGEVMPTSRVKPMTLPFFDVKVVAGFPIPLNNDELAQDIEVLKMLCPHPDSSYLIRVQGRSMIEAGVNDGDIIIVDKS
ERNPTEKQIAVCELNGEYTLKRVCKKEGILWLVPANPEYPEIKIIDGDDFSVWGVVTYIIHKPVY
>Mature_224_residues
GNQEKQVIKQAENQPKKPGRGGKRPGAGRPKGTSKLYAFRADNEVAAYLDSQENKTDFIKECIVWQMEVAKSRQEDEALM
QLGEVMPTSRVKPMTLPFFDVKVVAGFPIPLNNDELAQDIEVLKMLCPHPDSSYLIRVQGRSMIEAGVNDGDIIIVDKSE
RNPTEKQIAVCELNGEYTLKRVCKKEGILWLVPANPEYPEIKIIDGDDFSVWGVVTYIIHKPVY

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=126, Percent_Identity=34.1269841269841, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 25320; Mature: 25189

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNQEKQVIKQAENQPKKPGRGGKRPGAGRPKGTSKLYAFRADNEVAAYLDSQENKTDFI
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHH
KECIVWQMEVAKSRQEDEALMQLGEVMPTSRVKPMTLPFFDVKVVAGFPIPLNNDELAQD
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCEEEEEEEEECCCCCCCHHHHHH
IEVLKMLCPHPDSSYLIRVQGRSMIEAGVNDGDIIIVDKSERNPTEKQIAVCELNGEYTL
HHHHHHHCCCCCCCEEEEECCCEEEECCCCCCCEEEEECCCCCCCCCEEEEEEECCCHHH
KRVCKKEGILWLVPANPEYPEIKIIDGDDFSVWGVVTYIIHKPVY
HHHHHHCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GNQEKQVIKQAENQPKKPGRGGKRPGAGRPKGTSKLYAFRADNEVAAYLDSQENKTDFI
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHH
KECIVWQMEVAKSRQEDEALMQLGEVMPTSRVKPMTLPFFDVKVVAGFPIPLNNDELAQD
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCEEEEEEEEECCCCCCCHHHHHH
IEVLKMLCPHPDSSYLIRVQGRSMIEAGVNDGDIIIVDKSERNPTEKQIAVCELNGEYTL
HHHHHHHCCCCCCCEEEEECCCEEEECCCCCCCEEEEECCCCCCCCCEEEEEEECCCHHH
KRVCKKEGILWLVPANPEYPEIKIIDGDDFSVWGVVTYIIHKPVY
HHHHHHCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2144275; 2203737; 11677609; 1910151 [H]