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The map label for this gene is mutS [H]

Identifier: 150005893

GI number: 150005893

Start: 4231976

End: 4233244

Strand: Direct

Name: mutS [H]

Synonym: BVU_3389

Alternate gene names: 150005893

Gene position: 4231976-4233244 (Clockwise)

Preceding gene: 150005892

Following gene: 150005894

Centisome position: 81.96

GC content: 52.48

Gene sequence:

>1269_bases
ATGGTCAAGAAGAATGCAGAGAAGGATGCCGGTTTTGTCCAGCAGTTCAACGAATTGAAGAAGAAACATCCCGATGCGGT
GCTGCTTTTCCGCAAGGGCGACTTCTACGAAATGTACAAGGAGGATGCACTCAAAGCATCGGTGATACTGGCGCTGAAGG
TATCAGACAAGATTCTGCCGCTGGAAAATGACCCCATCAAGCTCCTGACCTTTCCCCGTCATGAACTGGACAAGCATCTG
CCCAAGCTGATTCGCTCTGGTCAGCGGGTCGCCATCTGCGAGGCGATAGACCAGCCGAAATTGATGAAGAAGCCCAGAGA
GAAGACCGGGAAAGAATTGAAAGAAACGAACACCTCTAACAAGAATACTATGGCGAAAAAGAAGAAAGAACAGGCTGTGC
AGGAAGAGCCTACCAAGACTGTGAAAAGTGCAGTGGAGGAAAAACCTGCCAAGGAAATGAAGAGTGAACAAGCAACCGAG
CAGAAAGCGGAAGCCAAGCAGGAACGCAAGCCACGCGAACCGCAGATGATTACCGCCAACGGCGAGAAAGTCAGCCACGG
CCATGCCTTCCAGAGCACCATCAACCCGGCGGACTGGTACTTCACCGCCAAGATTGACGGCGTACAGCTGAAGCCACAGA
AGATGGACGCTGCGGATTTGGCCGCTTACCAAAAGAAGGAAATGACGGTGCCCCAGCTGATGGAGAGGTATTATCCGACC
AAGCTCATGCCGAAGGTATCGGAAGAAGCGTACCAAATGCCGAAGCAATTGTCTGGCCCTGATGGTGCCATCACCATCGA
CAAGTTCAATGTCTATAAGGAAAAGGATGAACAGCGCCCGGACTACAGCAAGTATAAGTTCTATGTGCAGATGGGCGACA
CCAAGATGTCGGCCGTGGCATCCCGTGAGGACCTGGATGCCTACTTCGACCGGGTGGTCAGTCCCACACAACTTGTGGAA
AAGAACTTTGGGGAGCGCCTGCATCTGCAGTCAGCCTACGAGAAGTACCAGCTTCCCGAGGGAGTGGACCCCAAGGGAGT
CCGTGTGGCCAAGGACCACTCCGACAACAAATGGAAGGTGTCGATGGACCTGGGCGACAAGGGCAAGACCAGCAAGCATG
AAATCTCCTTCGACGACGGCTACTCGCTCTTCAAAGCCAAGACCGCTACCCGTGAACAGATTGCAGCCAAGTACCTCAAT
ACGGAAATCACAGGTATGCTTTCAGCCGTGACCAACAAACTGGAGAAGTCGGCTTCCATGAAAATGTAA

Upstream 100 bases:

>100_bases
CCAGCAGGTGGTGGACAAACAGTCACAGGAAAGAGCCTTGAAACTCCATGCGCCCAAAACAGAAAAATCCCAAGGTCTCA
AACTCTAAATCCTTTTCCCT

Downstream 100 bases:

>100_bases
CAAAATCAAGAGAAACAAACGAATATTCAAGAAACAATAAAAGACGAAAAGATATGACAGCTAAAAAGACACACGAGGAG
TTGGTGGAACTCCTTCAGGC

Product: putative DNA mismatch repair protein mutS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MVKKNAEKDAGFVQQFNELKKKHPDAVLLFRKGDFYEMYKEDALKASVILALKVSDKILPLENDPIKLLTFPRHELDKHL
PKLIRSGQRVAICEAIDQPKLMKKPREKTGKELKETNTSNKNTMAKKKKEQAVQEEPTKTVKSAVEEKPAKEMKSEQATE
QKAEAKQERKPREPQMITANGEKVSHGHAFQSTINPADWYFTAKIDGVQLKPQKMDAADLAAYQKKEMTVPQLMERYYPT
KLMPKVSEEAYQMPKQLSGPDGAITIDKFNVYKEKDEQRPDYSKYKFYVQMGDTKMSAVASREDLDAYFDRVVSPTQLVE
KNFGERLHLQSAYEKYQLPEGVDPKGVRVAKDHSDNKWKVSMDLGDKGKTSKHEISFDDGYSLFKAKTATREQIAAKYLN
TEITGMLSAVTNKLEKSASMKM

Sequences:

>Translated_422_residues
MVKKNAEKDAGFVQQFNELKKKHPDAVLLFRKGDFYEMYKEDALKASVILALKVSDKILPLENDPIKLLTFPRHELDKHL
PKLIRSGQRVAICEAIDQPKLMKKPREKTGKELKETNTSNKNTMAKKKKEQAVQEEPTKTVKSAVEEKPAKEMKSEQATE
QKAEAKQERKPREPQMITANGEKVSHGHAFQSTINPADWYFTAKIDGVQLKPQKMDAADLAAYQKKEMTVPQLMERYYPT
KLMPKVSEEAYQMPKQLSGPDGAITIDKFNVYKEKDEQRPDYSKYKFYVQMGDTKMSAVASREDLDAYFDRVVSPTQLVE
KNFGERLHLQSAYEKYQLPEGVDPKGVRVAKDHSDNKWKVSMDLGDKGKTSKHEISFDDGYSLFKAKTATREQIAAKYLN
TEITGMLSAVTNKLEKSASMKM
>Mature_422_residues
MVKKNAEKDAGFVQQFNELKKKHPDAVLLFRKGDFYEMYKEDALKASVILALKVSDKILPLENDPIKLLTFPRHELDKHL
PKLIRSGQRVAICEAIDQPKLMKKPREKTGKELKETNTSNKNTMAKKKKEQAVQEEPTKTVKSAVEEKPAKEMKSEQATE
QKAEAKQERKPREPQMITANGEKVSHGHAFQSTINPADWYFTAKIDGVQLKPQKMDAADLAAYQKKEMTVPQLMERYYPT
KLMPKVSEEAYQMPKQLSGPDGAITIDKFNVYKEKDEQRPDYSKYKFYVQMGDTKMSAVASREDLDAYFDRVVSPTQLVE
KNFGERLHLQSAYEKYQLPEGVDPKGVRVAKDHSDNKWKVSMDLGDKGKTSKHEISFDDGYSLFKAKTATREQIAAKYLN
TEITGMLSAVTNKLEKSASMKM

Specific function: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity [H]

COG id: COG0249

COG function: function code L; Mismatch repair ATPase (MutS family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA mismatch repair mutS family [H]

Homologues:

Organism=Escherichia coli, GI1789089, Length=105, Percent_Identity=35.2380952380952, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005748
- InterPro:   IPR007695
- InterPro:   IPR000432
- InterPro:   IPR007861
- InterPro:   IPR007860
- InterPro:   IPR007696
- InterPro:   IPR016151 [H]

Pfam domain/function: PF01624 MutS_I; PF05188 MutS_II; PF05192 MutS_III; PF05190 MutS_IV; PF00488 MutS_V [H]

EC number: NA

Molecular weight: Translated: 48173; Mature: 48173

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKKNAEKDAGFVQQFNELKKKHPDAVLLFRKGDFYEMYKEDALKASVILALKVSDKILP
CCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHEEEEEEEEECCCEEC
LENDPIKLLTFPRHELDKHLPKLIRSGQRVAICEAIDQPKLMKKPREKTGKELKETNTSN
CCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEHHCCCCHHHHCCHHHHHHHHHHCCCCC
KNTMAKKKKEQAVQEEPTKTVKSAVEEKPAKEMKSEQATEQKAEAKQERKPREPQMITAN
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
GEKVSHGHAFQSTINPADWYFTAKIDGVQLKPQKMDAADLAAYQKKEMTVPQLMERYYPT
CCCCCCCCHHHHCCCCCCEEEEEEECCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHCCC
KLMPKVSEEAYQMPKQLSGPDGAITIDKFNVYKEKDEQRPDYSKYKFYVQMGDTKMSAVA
HHCHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHCCCCCCCCEEEEEEECCCHHHHHH
SREDLDAYFDRVVSPTQLVEKNFGERLHLQSAYEKYQLPEGVDPKGVRVAKDHSDNKWKV
HHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEE
SMDLGDKGKTSKHEISFDDGYSLFKAKTATREQIAAKYLNTEITGMLSAVTNKLEKSASM
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KM
CC
>Mature Secondary Structure
MVKKNAEKDAGFVQQFNELKKKHPDAVLLFRKGDFYEMYKEDALKASVILALKVSDKILP
CCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHEEEEEEEEECCCEEC
LENDPIKLLTFPRHELDKHLPKLIRSGQRVAICEAIDQPKLMKKPREKTGKELKETNTSN
CCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEHHCCCCHHHHCCHHHHHHHHHHCCCCC
KNTMAKKKKEQAVQEEPTKTVKSAVEEKPAKEMKSEQATEQKAEAKQERKPREPQMITAN
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
GEKVSHGHAFQSTINPADWYFTAKIDGVQLKPQKMDAADLAAYQKKEMTVPQLMERYYPT
CCCCCCCCHHHHCCCCCCEEEEEEECCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHCCC
KLMPKVSEEAYQMPKQLSGPDGAITIDKFNVYKEKDEQRPDYSKYKFYVQMGDTKMSAVA
HHCHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHCCCCCCCCEEEEEEECCCHHHHHH
SREDLDAYFDRVVSPTQLVEKNFGERLHLQSAYEKYQLPEGVDPKGVRVAKDHSDNKWKV
HHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEE
SMDLGDKGKTSKHEISFDDGYSLFKAKTATREQIAAKYLNTEITGMLSAVTNKLEKSASM
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KM
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA