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The map label for this gene is fldA [H]

Identifier: 150005724

GI number: 150005724

Start: 4042159

End: 4042662

Strand: Direct

Name: fldA [H]

Synonym: BVU_3217

Alternate gene names: 150005724

Gene position: 4042159-4042662 (Clockwise)

Preceding gene: 150005723

Following gene: 150005725

Centisome position: 78.29

GC content: 37.9

Gene sequence:

>504_bases
ATGAAAAAAATGGGTATAATTTATGGTTCCTCTACTGGAACTTGTGAGAGCATCGCACAGACAATAGCTGAAAAATTAGG
TGTGGCATCAGTTGATGTAATTGATGCAAGTAAAATTACCACAGAAAAAGTGGAAAGTTATGATATTTTATTGTTAGGGA
CTTCTACTTGGGGAGACGGTGAATTGCAAGATGATTGGTATGACGCCATTAAAACGATAAAGACTGCAGATTTGAATGGT
AAAATAGTTGCTCTCTTTGGCTGTGGAGATTCAGAATCCTATTGTGATACATTTTGTGACGGTATGGGAGTTATATATGA
CCAGTTAAAGAATTCAGGTTGCACTTTTGTGGGGGCAGTTTCTGCCGATGGGTATTCGTATTCATCTTCTATAGCGATAA
TCGATGGGAAATTTGTAGGTTTGGCTCTTGATGACGTGAACGAAAGTGGCAAGACTGAAGAACGTATTAACAGTTGGGTT
GAAGAAATAAAGAAGAACCTGTAA

Upstream 100 bases:

>100_bases
GTTTTGTCTCTTGAACTTTATTAAAATCACTATTTCTAGGTATTTCAGAATCTCTTTCAAACCTTTTACTTTGCAACAAA
CAAATTAAATGATTTGCTGT

Downstream 100 bases:

>100_bases
TTTTGACAATTGCCTTATGATAGCTTCAGACATAAACCCGGTAGAATTGAAAGTATTTCTGAATCATATTTATGAATTAA
AAAAAGGAGTACGTCAGATG

Product: flavodoxin FldA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MKKMGIIYGSSTGTCESIAQTIAEKLGVASVDVIDASKITTEKVESYDILLLGTSTWGDGELQDDWYDAIKTIKTADLNG
KIVALFGCGDSESYCDTFCDGMGVIYDQLKNSGCTFVGAVSADGYSYSSSIAIIDGKFVGLALDDVNESGKTEERINSWV
EEIKKNL

Sequences:

>Translated_167_residues
MKKMGIIYGSSTGTCESIAQTIAEKLGVASVDVIDASKITTEKVESYDILLLGTSTWGDGELQDDWYDAIKTIKTADLNG
KIVALFGCGDSESYCDTFCDGMGVIYDQLKNSGCTFVGAVSADGYSYSSSIAIIDGKFVGLALDDVNESGKTEERINSWV
EEIKKNL
>Mature_167_residues
MKKMGIIYGSSTGTCESIAQTIAEKLGVASVDVIDASKITTEKVESYDILLLGTSTWGDGELQDDWYDAIKTIKTADLNG
KIVALFGCGDSESYCDTFCDGMGVIYDQLKNSGCTFVGAVSADGYSYSSSIAIIDGKFVGLALDDVNESGKTEERINSWV
EEIKKNL

Specific function: Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase [H]

COG id: COG0716

COG function: function code C; Flavodoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1786900, Length=168, Percent_Identity=45.2380952380952, Blast_Score=148, Evalue=2e-37,
Organism=Escherichia coli, GI1789262, Length=167, Percent_Identity=39.5209580838323, Blast_Score=126, Evalue=7e-31,

Paralogues:

None

Copy number: 242 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR001226
- InterPro:   IPR010086 [H]

Pfam domain/function: PF00258 Flavodoxin_1 [H]

EC number: NA

Molecular weight: Translated: 17904; Mature: 17904

Theoretical pI: Translated: 4.03; Mature: 4.03

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMGIIYGSSTGTCESIAQTIAEKLGVASVDVIDASKITTEKVESYDILLLGTSTWGDG
CCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCEEEEEEECCCCCCC
ELQDDWYDAIKTIKTADLNGKIVALFGCGDSESYCDTFCDGMGVIYDQLKNSGCTFVGAV
CCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHCCCCCEEEEEE
SADGYSYSSSIAIIDGKFVGLALDDVNESGKTEERINSWVEEIKKNL
CCCCCCCCCEEEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKMGIIYGSSTGTCESIAQTIAEKLGVASVDVIDASKITTEKVESYDILLLGTSTWGDG
CCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCEEEEEEECCCCCCC
ELQDDWYDAIKTIKTADLNGKIVALFGCGDSESYCDTFCDGMGVIYDQLKNSGCTFVGAV
CCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHCCCCCEEEEEE
SADGYSYSSSIAIIDGKFVGLALDDVNESGKTEERINSWVEEIKKNL
CCCCCCCCCEEEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]