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The map label for this gene is uvrB [H]

Identifier: 150005555

GI number: 150005555

Start: 3847329

End: 3849362

Strand: Reverse

Name: uvrB [H]

Synonym: BVU_3040

Alternate gene names: 150005555

Gene position: 3849362-3847329 (Counterclockwise)

Preceding gene: 150005559

Following gene: 150005551

Centisome position: 74.55

GC content: 47.74

Gene sequence:

>2034_bases
ATGAATTTTGAATTGATTTCCGAATACCAACCCACCGGTGACCAACCGGAAGCTATCGCCCAGCTGACCGAAGGGGTGCT
GGAAGGAGTCCCCGCACAAACTTTATTGGGGGTCACCGGGTCCGGCAAGACTTTCACGATTGCAAATGTAATTAAAAACA
TCAATAAGCCCACCTTGATATTAAGCCATAACAAAACATTGGCAGCCCAGTTATACGGAGAGTTCAAGAGTTTCTTTCCC
AATAATGCTGTGGAATACTATGTATCTTATTATGACTATTACCAGCCGGAAGCATATTTGCCGTCCAGCGACACCTATAT
AGAAAAGGATCTGGCCATTAATGAAGAGATTGACAAATTGCGGCTGGCTGCCACCTCTGCCCTGCTGTCGGGACGGAAGG
ACGTGGTGGTGGTGTCTTCCGTGTCCTGCATCTACGGTATGGGGAACCCGTCGGATTTCTATAATAACGTAATCGAGATA
AAAAAAGGCAAACTGCTGGACAGGAATGTATTTTTACGCCGCTTGGTGGACAGCCTGTATGTGCGTAACGACATAGAACT
GAATCGCGGGAATTTCCGCGTAAAAGGTGACACGGTAGACATTTACCTGGCATATAGCGACAATCTCCTCCGGGTTATGT
TTTGGGACGATGAAATTGATGCCATTGAAGAGATAGACCCTATTTCGGGAATCCGTCTGGCAACTTTTGATGAATACAAA
ATTTATCCGGCCAATCTTTTTATGACCACCAAAGAGAGCCAGTTGAGAGCTATTCATCAGATTGAGGACGACTTGACGAA
AGAGGTGGCCAAATTCGAGGAGGAAGGAAAAATGTATGAGGCGAAACGACTCTATGAGCGCGTGACATACGATATGGAGA
TGATTCGCGAACTGGGGCATTGTTCGGGCATAGAAAATTATTCCCGCTACTTTGACGGGCGTAATGCAGGTACCCGTCCT
TACTGTCTGCTGGACTTCTTTCCGGATGATTTCCTGATTGTAATAGACGAAAGCCATGTCAGCGTACCGCAAATACGTGC
CATGTATGGTGGTGACCGGGCCAGAAAAACCAATTTGGTGGAATATGGTTTCCGGATGGAGTCGGCTTTTGACAACCGTC
CTCTAAAATTTGAAGAGTTCAAGGAACTGGCCAAACAAGTGATTTATGTCAGTGCCACACCTGCCGATTATGAATTGGTG
GAAAGTGAAGGCATTATCGTTGAACAGGTTATCCGTCCTACCGGATTGCTGGACCCGGTAATTGAAGTACGCCCCAGTCT
GAATCAGATTGACGACCTGATGGAAGAGATACAGCAACGCATCGAGAAAGAAGAACGTGTACTGGTGACCACGCTTACCA
AACGCATGGCAGAAGAATTGACCGAATATCTGCTGCGCAATGACATCCGCTGCAACTACATCCACAGCGATGTGGACACT
TTGGAACGCGTCAAGATTATGGATGAATTACGTCAGGGCGTTTATGATGTACTGGTGGGTGTGAATTTGCTTCGTGAAGG
TCTGGACTTGCCCGAAGTGTCTTTGGTCGCCATTCTGGATGCAGACAAAGAAGGGTTCCTCCGCTCCCACCGTTCGCTGA
CCCAGACAGCAGGACGCGCCGCCCGCAATATCAATGGAAAAGTAATCATGTATGCAGACCGCATGACGGACAGCATGAAA
AAAACGATAGACGAAACCAACCGCCGTCGTGAAAAACAGCTGGCATATAACGAAGAGCATGGAATCACCCCCAAACAGAT
ACAGCGTGCGCGGAATGCTGCCTTGTTGGGCAACAACAGCAACGAAGTTGCCGGAACCACTCAAGGCCCCAAGGCATACA
TCGAGCCATCTTCCGATACAACGGCTGCCGACCCGATTGTTCAGTATATGACCAAGCCACAGATGGAGAAAACGATAGAA
CGTACCCGGAAACTGATGCAGGAAGCTGCCAAGAAGCTGGAATTTATAGAAGCTGCACAATACAGGGATGAGCTGCTGAA
ACTGGAAGATATGATGAAAGAGAGATGGGGATAG

Upstream 100 bases:

>100_bases
AATGCTAAAAAGTCGACAAGAGTCTATTTTTTAGAGATGAATAGATAATATCTAAGGAAATAACTGTATTTTTACATCTC
ATTAAACCAAACATGCTATT

Downstream 100 bases:

>100_bases
GCTTGTCTCCTTGGCGGAAGAAGGCGCACTGCCTGTCGAGGAAAAGCCTGTTACCCGAAGAAATATCACGGATATGCCGG
TGAGTTCCGGAATAAAGGCA

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MNFELISEYQPTGDQPEAIAQLTEGVLEGVPAQTLLGVTGSGKTFTIANVIKNINKPTLILSHNKTLAAQLYGEFKSFFP
NNAVEYYVSYYDYYQPEAYLPSSDTYIEKDLAINEEIDKLRLAATSALLSGRKDVVVVSSVSCIYGMGNPSDFYNNVIEI
KKGKLLDRNVFLRRLVDSLYVRNDIELNRGNFRVKGDTVDIYLAYSDNLLRVMFWDDEIDAIEEIDPISGIRLATFDEYK
IYPANLFMTTKESQLRAIHQIEDDLTKEVAKFEEEGKMYEAKRLYERVTYDMEMIRELGHCSGIENYSRYFDGRNAGTRP
YCLLDFFPDDFLIVIDESHVSVPQIRAMYGGDRARKTNLVEYGFRMESAFDNRPLKFEEFKELAKQVIYVSATPADYELV
ESEGIIVEQVIRPTGLLDPVIEVRPSLNQIDDLMEEIQQRIEKEERVLVTTLTKRMAEELTEYLLRNDIRCNYIHSDVDT
LERVKIMDELRQGVYDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRSHRSLTQTAGRAARNINGKVIMYADRMTDSMK
KTIDETNRRREKQLAYNEEHGITPKQIQRARNAALLGNNSNEVAGTTQGPKAYIEPSSDTTAADPIVQYMTKPQMEKTIE
RTRKLMQEAAKKLEFIEAAQYRDELLKLEDMMKERWG

Sequences:

>Translated_677_residues
MNFELISEYQPTGDQPEAIAQLTEGVLEGVPAQTLLGVTGSGKTFTIANVIKNINKPTLILSHNKTLAAQLYGEFKSFFP
NNAVEYYVSYYDYYQPEAYLPSSDTYIEKDLAINEEIDKLRLAATSALLSGRKDVVVVSSVSCIYGMGNPSDFYNNVIEI
KKGKLLDRNVFLRRLVDSLYVRNDIELNRGNFRVKGDTVDIYLAYSDNLLRVMFWDDEIDAIEEIDPISGIRLATFDEYK
IYPANLFMTTKESQLRAIHQIEDDLTKEVAKFEEEGKMYEAKRLYERVTYDMEMIRELGHCSGIENYSRYFDGRNAGTRP
YCLLDFFPDDFLIVIDESHVSVPQIRAMYGGDRARKTNLVEYGFRMESAFDNRPLKFEEFKELAKQVIYVSATPADYELV
ESEGIIVEQVIRPTGLLDPVIEVRPSLNQIDDLMEEIQQRIEKEERVLVTTLTKRMAEELTEYLLRNDIRCNYIHSDVDT
LERVKIMDELRQGVYDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRSHRSLTQTAGRAARNINGKVIMYADRMTDSMK
KTIDETNRRREKQLAYNEEHGITPKQIQRARNAALLGNNSNEVAGTTQGPKAYIEPSSDTTAADPIVQYMTKPQMEKTIE
RTRKLMQEAAKKLEFIEAAQYRDELLKLEDMMKERWG
>Mature_677_residues
MNFELISEYQPTGDQPEAIAQLTEGVLEGVPAQTLLGVTGSGKTFTIANVIKNINKPTLILSHNKTLAAQLYGEFKSFFP
NNAVEYYVSYYDYYQPEAYLPSSDTYIEKDLAINEEIDKLRLAATSALLSGRKDVVVVSSVSCIYGMGNPSDFYNNVIEI
KKGKLLDRNVFLRRLVDSLYVRNDIELNRGNFRVKGDTVDIYLAYSDNLLRVMFWDDEIDAIEEIDPISGIRLATFDEYK
IYPANLFMTTKESQLRAIHQIEDDLTKEVAKFEEEGKMYEAKRLYERVTYDMEMIRELGHCSGIENYSRYFDGRNAGTRP
YCLLDFFPDDFLIVIDESHVSVPQIRAMYGGDRARKTNLVEYGFRMESAFDNRPLKFEEFKELAKQVIYVSATPADYELV
ESEGIIVEQVIRPTGLLDPVIEVRPSLNQIDDLMEEIQQRIEKEERVLVTTLTKRMAEELTEYLLRNDIRCNYIHSDVDT
LERVKIMDELRQGVYDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRSHRSLTQTAGRAARNINGKVIMYADRMTDSMK
KTIDETNRRREKQLAYNEEHGITPKQIQRARNAALLGNNSNEVAGTTQGPKAYIEPSSDTTAADPIVQYMTKPQMEKTIE
RTRKLMQEAAKKLEFIEAAQYRDELLKLEDMMKERWG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=673, Percent_Identity=54.9777117384844, Blast_Score=732, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: NA

Molecular weight: Translated: 77682; Mature: 77682

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50151 UVR ; PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFELISEYQPTGDQPEAIAQLTEGVLEGVPAQTLLGVTGSGKTFTIANVIKNINKPTLI
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHEEEECCCCCEEEHHHHHHCCCCCEEE
LSHNKTLAAQLYGEFKSFFPNNAVEYYVSYYDYYQPEAYLPSSDTYIEKDLAINEEIDKL
EECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCEEHHCCCCCHHHHHH
RLAATSALLSGRKDVVVVSSVSCIYGMGNPSDFYNNVIEIKKGKLLDRNVFLRRLVDSLY
HHHHHHHHHCCCCCEEEEEECHHEECCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHH
VRNDIELNRGNFRVKGDTVDIYLAYSDNLLRVMFWDDEIDAIEEIDPISGIRLATFDEYK
HCCCCEECCCCEEEECCEEEEEEEECCCEEEEEEECCCHHHHHHCCCCCCCEEEEECCCE
IYPANLFMTTKESQLRAIHQIEDDLTKEVAKFEEEGKMYEAKRLYERVTYDMEMIRELGH
EEECEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
CSGIENYSRYFDGRNAGTRPYCLLDFFPDDFLIVIDESHVSVPQIRAMYGGDRARKTNLV
CCCCHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHCCCHHHHCCHH
EYGFRMESAFDNRPLKFEEFKELAKQVIYVSATPADYELVESEGIIVEQVIRPTGLLDPV
HHCCCHHHHCCCCCCCHHHHHHHHHHEEEEECCCCCCHHHCCCCCHHHHHHCCCCCCCHH
IEVRPSLNQIDDLMEEIQQRIEKEERVLVTTLTKRMAEELTEYLLRNDIRCNYIHSDVDT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHH
LERVKIMDELRQGVYDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRSHRSLTQTAGRA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHH
ARNINGKVIMYADRMTDSMKKTIDETNRRREKQLAYNEEHGITPKQIQRARNAALLGNNS
HHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEECCCC
NEVAGTTQGPKAYIEPSSDTTAADPIVQYMTKPQMEKTIERTRKLMQEAAKKLEFIEAAQ
CCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRDELLKLEDMMKERWG
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFELISEYQPTGDQPEAIAQLTEGVLEGVPAQTLLGVTGSGKTFTIANVIKNINKPTLI
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHEEEECCCCCEEEHHHHHHCCCCCEEE
LSHNKTLAAQLYGEFKSFFPNNAVEYYVSYYDYYQPEAYLPSSDTYIEKDLAINEEIDKL
EECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCEEHHCCCCCHHHHHH
RLAATSALLSGRKDVVVVSSVSCIYGMGNPSDFYNNVIEIKKGKLLDRNVFLRRLVDSLY
HHHHHHHHHCCCCCEEEEEECHHEECCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHH
VRNDIELNRGNFRVKGDTVDIYLAYSDNLLRVMFWDDEIDAIEEIDPISGIRLATFDEYK
HCCCCEECCCCEEEECCEEEEEEEECCCEEEEEEECCCHHHHHHCCCCCCCEEEEECCCE
IYPANLFMTTKESQLRAIHQIEDDLTKEVAKFEEEGKMYEAKRLYERVTYDMEMIRELGH
EEECEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
CSGIENYSRYFDGRNAGTRPYCLLDFFPDDFLIVIDESHVSVPQIRAMYGGDRARKTNLV
CCCCHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHCCCHHHHCCHH
EYGFRMESAFDNRPLKFEEFKELAKQVIYVSATPADYELVESEGIIVEQVIRPTGLLDPV
HHCCCHHHHCCCCCCCHHHHHHHHHHEEEEECCCCCCHHHCCCCCHHHHHHCCCCCCCHH
IEVRPSLNQIDDLMEEIQQRIEKEERVLVTTLTKRMAEELTEYLLRNDIRCNYIHSDVDT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHH
LERVKIMDELRQGVYDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRSHRSLTQTAGRA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHH
ARNINGKVIMYADRMTDSMKKTIDETNRRREKQLAYNEEHGITPKQIQRARNAALLGNNS
HHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEECCCC
NEVAGTTQGPKAYIEPSSDTTAADPIVQYMTKPQMEKTIERTRKLMQEAAKKLEFIEAAQ
CCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRDELLKLEDMMKERWG
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA