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The map label for this gene is bdhA [H]

Identifier: 150005531

GI number: 150005531

Start: 3817531

End: 3818706

Strand: Reverse

Name: bdhA [H]

Synonym: BVU_3015

Alternate gene names: 150005531

Gene position: 3818706-3817531 (Counterclockwise)

Preceding gene: 150005535

Following gene: 150005530

Centisome position: 73.96

GC content: 44.56

Gene sequence:

>1176_bases
ATGAACAATTTTGTATTTTACAGCCCTACCGAGTTTGTATTTGGCAAGGATACAGATATCCAAACCGGTACTCTTGCTAA
AAAGTATAACGCCCGGAAGGCAATGATTGTTTACGGTGGAGGCTCTATTATTCGCAGCGGATTACTGCAACGCATAGAAG
ATTCTCTGCAACAGGCAGGAGTGGATTATGTAAAATTAGGAGGCGTACAACCTAATCCTACTGACCCGAAAGTTTACGAA
GGCATTGAACTGGCGCGCAAAGAAGGCGTGGACTTTATGCTTCCCGTAGGGGGAGGCTCTGTCATTGACACTGCAAAAGC
CATTGCGGCAGGAGTGCCCTACGAAGGTGATTTTTGGGATTTCTATATAGGAAAAGCCAAAGTGAAGAAGGCCTTAAAAG
TGGGTGTGGTACTTACTATTCCCGCTGCCGGCAGCGAAGGTTCGGGCAATACGGTGATTACCAAACTGGAAGGTCTGCAA
AAACTAAGTTTGCGTGTACCGGAATTACTACGGCCTGTTTTTGCTGTGATGAATCCGGAGCTGACCTATACTCTCCCCCC
CTACCAGACAGCTTGTGGCATTGCCGATATGATGGTACACATTATGGAACGTTATTTTACCAACACTCCCGATGTAGAAA
TCAGTGACCGGCTGTGTGAAGGGACTTTGATGGCTATCATCAAAGAAGCATATAAAGTGAAGCAGAACCCGAACGATTAC
GAAGCACGCGCCAATATCATGTGGTGTGGGACAATTGCCCATAACGGTACTTGCGGAGTAGGTTGTGAGGAAGACTGGGC
ATCACATTTTCTGGAACATGAAATCAGTGCTGTATATAATGTGACACATGGAGCAGGACTAGCAGTAATCGTACCTGCAT
GGATGACATTCATGGCAGAACATAACCCGAAAAAGATTGCCCGGTTTGCAAACCGCGTTTTCGGAGTTCCCGAGAATGAG
GATTTGGAAGAAATGGCACTTGCCGGCATATCACGATTGAAGCATTTTTTCAGATACATGGGCCTGCCGGTCAATTTCAA
AGAATTGGGTATAGAACATCCTGATATTGAACTGCTAGTGAAAAAACTGCATGAAAACAAAGGTGAATTAGTAGGTAATT
ATGTAAAACTGAACAAAGAATACAGTAAAGAGATATTCGAACTAGCCTGCAAATAA

Upstream 100 bases:

>100_bases
GTCCGTTTTCATCTTTTTACTAAATTTAGGCGGCAAAGGTAATATATTTCCTTAACTTTGTTTTGGTTTCAAACAACAAA
ATAATATAAGGAGTAAGCAA

Downstream 100 bases:

>100_bases
CCCGCACAGCCCAACTGTTCTAAAATATAGGCATCCGGTTTATCTGCCTTTATTTCATTCAGAACCGTAAAGCTCCTAAA
GTATTCTATTTTCCAGACGC

Product: Fe-dependent alcohol dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: BDH I [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MNNFVFYSPTEFVFGKDTDIQTGTLAKKYNARKAMIVYGGGSIIRSGLLQRIEDSLQQAGVDYVKLGGVQPNPTDPKVYE
GIELARKEGVDFMLPVGGGSVIDTAKAIAAGVPYEGDFWDFYIGKAKVKKALKVGVVLTIPAAGSEGSGNTVITKLEGLQ
KLSLRVPELLRPVFAVMNPELTYTLPPYQTACGIADMMVHIMERYFTNTPDVEISDRLCEGTLMAIIKEAYKVKQNPNDY
EARANIMWCGTIAHNGTCGVGCEEDWASHFLEHEISAVYNVTHGAGLAVIVPAWMTFMAEHNPKKIARFANRVFGVPENE
DLEEMALAGISRLKHFFRYMGLPVNFKELGIEHPDIELLVKKLHENKGELVGNYVKLNKEYSKEIFELACK

Sequences:

>Translated_391_residues
MNNFVFYSPTEFVFGKDTDIQTGTLAKKYNARKAMIVYGGGSIIRSGLLQRIEDSLQQAGVDYVKLGGVQPNPTDPKVYE
GIELARKEGVDFMLPVGGGSVIDTAKAIAAGVPYEGDFWDFYIGKAKVKKALKVGVVLTIPAAGSEGSGNTVITKLEGLQ
KLSLRVPELLRPVFAVMNPELTYTLPPYQTACGIADMMVHIMERYFTNTPDVEISDRLCEGTLMAIIKEAYKVKQNPNDY
EARANIMWCGTIAHNGTCGVGCEEDWASHFLEHEISAVYNVTHGAGLAVIVPAWMTFMAEHNPKKIARFANRVFGVPENE
DLEEMALAGISRLKHFFRYMGLPVNFKELGIEHPDIELLVKKLHENKGELVGNYVKLNKEYSKEIFELACK
>Mature_391_residues
MNNFVFYSPTEFVFGKDTDIQTGTLAKKYNARKAMIVYGGGSIIRSGLLQRIEDSLQQAGVDYVKLGGVQPNPTDPKVYE
GIELARKEGVDFMLPVGGGSVIDTAKAIAAGVPYEGDFWDFYIGKAKVKKALKVGVVLTIPAAGSEGSGNTVITKLEGLQ
KLSLRVPELLRPVFAVMNPELTYTLPPYQTACGIADMMVHIMERYFTNTPDVEISDRLCEGTLMAIIKEAYKVKQNPNDY
EARANIMWCGTIAHNGTCGVGCEEDWASHFLEHEISAVYNVTHGAGLAVIVPAWMTFMAEHNPKKIARFANRVFGVPENE
DLEEMALAGISRLKHFFRYMGLPVNFKELGIEHPDIELLVKKLHENKGELVGNYVKLNKEYSKEIFELACK

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=350, Percent_Identity=25.7142857142857, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1789386, Length=392, Percent_Identity=35.969387755102, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1789163, Length=338, Percent_Identity=26.9230769230769, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI48994951, Length=366, Percent_Identity=23.7704918032787, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787493, Length=361, Percent_Identity=25.7617728531856, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17537053, Length=413, Percent_Identity=23.4866828087167, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321181, Length=384, Percent_Identity=27.6041666666667, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24657991, Length=396, Percent_Identity=23.2323232323232, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 43297; Mature: 43297

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFVFYSPTEFVFGKDTDIQTGTLAKKYNARKAMIVYGGGSIIRSGLLQRIEDSLQQAG
CCCCEEECCCCEEECCCCCCCCCCHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
VDYVKLGGVQPNPTDPKVYEGIELARKEGVDFMLPVGGGSVIDTAKAIAAGVPYEGDFWD
CCEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCE
FYIGKAKVKKALKVGVVLTIPAAGSEGSGNTVITKLEGLQKLSLRVPELLRPVFAVMNPE
EECCHHHHHHHHHCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
LTYTLPPYQTACGIADMMVHIMERYFTNTPDVEISDRLCEGTLMAIIKEAYKVKQNPNDY
EEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
EARANIMWCGTIAHNGTCGVGCEEDWASHFLEHEISAVYNVTHGAGLAVIVPAWMTFMAE
HHEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
HNPKKIARFANRVFGVPENEDLEEMALAGISRLKHFFRYMGLPVNFKELGIEHPDIELLV
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHH
KKLHENKGELVGNYVKLNKEYSKEIFELACK
HHHHCCCCHHHHHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure
MNNFVFYSPTEFVFGKDTDIQTGTLAKKYNARKAMIVYGGGSIIRSGLLQRIEDSLQQAG
CCCCEEECCCCEEECCCCCCCCCCHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
VDYVKLGGVQPNPTDPKVYEGIELARKEGVDFMLPVGGGSVIDTAKAIAAGVPYEGDFWD
CCEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCE
FYIGKAKVKKALKVGVVLTIPAAGSEGSGNTVITKLEGLQKLSLRVPELLRPVFAVMNPE
EECCHHHHHHHHHCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
LTYTLPPYQTACGIADMMVHIMERYFTNTPDVEISDRLCEGTLMAIIKEAYKVKQNPNDY
EEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
EARANIMWCGTIAHNGTCGVGCEEDWASHFLEHEISAVYNVTHGAGLAVIVPAWMTFMAE
HHEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
HNPKKIARFANRVFGVPENEDLEEMALAGISRLKHFFRYMGLPVNFKELGIEHPDIELLV
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHH
KKLHENKGELVGNYVKLNKEYSKEIFELACK
HHHHCCCCHHHHHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1385386; 11466286; 1809209 [H]