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The map label for this gene is gmhB [H]

Identifier: 148827911

GI number: 148827911

Start: 1301800

End: 1302354

Strand: Direct

Name: gmhB [H]

Synonym: CGSHiGG_07070

Alternate gene names: 148827911

Gene position: 1301800-1302354 (Clockwise)

Preceding gene: 148827907

Following gene: 148827912

Centisome position: 68.98

GC content: 36.58

Gene sequence:

>555_bases
ATGAATAAGGCTATTTTTTTAGATCGCGATGGCACGTTAAATATTGATTATGGTTATGTACACGAAATTGATAACTTTAA
ATTTATTGATGGTGCGATTGATGCATTGCGAGAATTAAAGAAAATGGGATATATGTTGGTATTAGTGACCAACCAGTCGG
GCATTGCACGTGGTTATTTTTCTGAGGATCAGTTTTTACAATTAACAGAATGGATGGATTGGTCGTTAGCTGAACAAGAT
GTGGATTTGGATGGCATTTACTATTGTCCACATCATTCTGAGGGAAAGGGCGAATATAAAGAAGATTGTGATTGTCGGAA
GCCTAAATCGGGAATGTTATTGCAAGCGATCAAAGAATTAAAGATCGATCCTACGCAATCTATTATGGTTGGAGATAAAG
TTGAAGACCTAAAAGCGGGGATTGGTGCGAAGGTAAAAATGAACGTATTAGTTCGTACTGGTAAACCAGTAACAGGGGAA
GGAGAAGGAATAGCAGATTATGTGTTAGATTCTATCGTAGATCTTCCGAGAATTTTAAAACGCTTAAAAAAATAG

Upstream 100 bases:

>100_bases
GATTATCTTTTTTAGACAGATTAGTTATGACTTATATTTGCTAATTGCTTGGATTAAATAGATAATTTTCGTCAATTTGA
CATGTATAAAAGGCAAGAGA

Downstream 100 bases:

>100_bases
CCAAAAAGATCTATATTTTGCTCTAATTGCTTGTACTTTAATCAAAAGATCATTTTTTTAAATATTTTTACAAAAAAGTA
CTTGCAAGGGATTTGAAAAT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNKAIFLDRDGTLNIDYGYVHEIDNFKFIDGAIDALRELKKMGYMLVLVTNQSGIARGYFSEDQFLQLTEWMDWSLAEQD
VDLDGIYYCPHHSEGKGEYKEDCDCRKPKSGMLLQAIKELKIDPTQSIMVGDKVEDLKAGIGAKVKMNVLVRTGKPVTGE
GEGIADYVLDSIVDLPRILKRLKK

Sequences:

>Translated_184_residues
MNKAIFLDRDGTLNIDYGYVHEIDNFKFIDGAIDALRELKKMGYMLVLVTNQSGIARGYFSEDQFLQLTEWMDWSLAEQD
VDLDGIYYCPHHSEGKGEYKEDCDCRKPKSGMLLQAIKELKIDPTQSIMVGDKVEDLKAGIGAKVKMNVLVRTGKPVTGE
GEGIADYVLDSIVDLPRILKRLKK
>Mature_184_residues
MNKAIFLDRDGTLNIDYGYVHEIDNFKFIDGAIDALRELKKMGYMLVLVTNQSGIARGYFSEDQFLQLTEWMDWSLAEQD
VDLDGIYYCPHHSEGKGEYKEDCDCRKPKSGMLLQAIKELKIDPTQSIMVGDKVEDLKAGIGAKVKMNVLVRTGKPVTGE
GEGIADYVLDSIVDLPRILKRLKK

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=182, Percent_Identity=66.4835164835165, Blast_Score=260, Evalue=3e-71,
Organism=Escherichia coli, GI87082027, Length=140, Percent_Identity=32.8571428571429, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20782; Mature: 20782

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAIFLDRDGTLNIDYGYVHEIDNFKFIDGAIDALRELKKMGYMLVLVTNQSGIARGYF
CCCCEEEECCCEEEECCCEEEECCCEEEHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
SEDQFLQLTEWMDWSLAEQDVDLDGIYYCPHHSEGKGEYKEDCDCRKPKSGMLLQAIKEL
CCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
KIDPTQSIMVGDKVEDLKAGIGAKVKMNVLVRTGKPVTGEGEGIADYVLDSIVDLPRILK
CCCCCCEEEECCCHHHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
RLKK
HHCC
>Mature Secondary Structure
MNKAIFLDRDGTLNIDYGYVHEIDNFKFIDGAIDALRELKKMGYMLVLVTNQSGIARGYF
CCCCEEEECCCEEEECCCEEEECCCEEEHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
SEDQFLQLTEWMDWSLAEQDVDLDGIYYCPHHSEGKGEYKEDCDCRKPKSGMLLQAIKEL
CCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
KIDPTQSIMVGDKVEDLKAGIGAKVKMNVLVRTGKPVTGEGEGIADYVLDSIVDLPRILK
CCCCCCEEEECCCHHHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
RLKK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 12101286 [H]