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The map label for this gene is fucI

Identifier: 148827904

GI number: 148827904

Start: 1292962

End: 1293711

Strand: Reverse

Name: fucI

Synonym: CGSHiGG_07025

Alternate gene names: 148827904

Gene position: 1293711-1292962 (Counterclockwise)

Preceding gene: 148827908

Following gene: 148827903

Centisome position: 68.55

GC content: 33.6

Gene sequence:

>750_bases
ATGAATTATCGTGATGAATTAATTTTACAATGGGTAAATCAACAAGGAAAAGCCAGCGTAATAGAACTTGCACAGCATTG
TGATATTTCGGTGGAAACCATTCGTCGCGATTTGAACAAATTAGCGAACAAAGGCTTATTGCACCGAACCCACGGAGGAG
CAGTGAGTAATAAAACCAAAGATTTAGGTTCATTTTTCCAAACTCGAAAACATATTAATGCAACAGCTAAACGACATATT
GCCCAAAAAGCCTTGGATTTGCTATATGAAAATGCCGTTATAGGTTTAGATGCAAGCTCAACAAGTTGGTATTTTGCTTA
TTTAATGCCCGATATTCCTTGTACAGTAGTAACCAATTCAATGTTTAACATTAATGCCCTAGTTAATAAATCCAATGTTA
AAACTATTGTTACTGGCGGAGTTTATTCAGCAAAATATGAAGCATTTTACGGTCCCTTATCTGAGTACTTATTACAACGA
TTACATATTAATTTTTCAGTGTTTTCTTGTTCAGGAATTGATAAAAACGGTAATATCTGGGAATCAAACGAGCTGAATGC
CTCTTTAAAACGAAAAATGATGGAAGCTTCAGAACGTGCTTATTTGTTAATTGATTCTTCTAAATTTGAAAAAACAAGTT
TGATTCAACTTGCCGATTTAAGCAAAATTAATACCATTTTTTCTGATCGGTCACTTCCCGATAACTTACAAAAATATTGT
GAGCAACACGATATAATGACCGTTTTATAA

Upstream 100 bases:

>100_bases
AGGAAGATATACGTCACCCCAATATAATTTATCCTTGGATTTTCAATATACTCAAGCGTAAACTAGAATCTCGACTAAAT
CCACCGTATAGGGAAAAGAG

Downstream 100 bases:

>100_bases
AAAAAGATGACCATTTTGACCGAAAATTACTAAAAATTGAAAGAATCGGTCATATACATTTCCTTAAATATGGTCAATTT
TTGTGATCTGCTTCTCAGTT

Product: L-fucose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MNYRDELILQWVNQQGKASVIELAQHCDISVETIRRDLNKLANKGLLHRTHGGAVSNKTKDLGSFFQTRKHINATAKRHI
AQKALDLLYENAVIGLDASSTSWYFAYLMPDIPCTVVTNSMFNINALVNKSNVKTIVTGGVYSAKYEAFYGPLSEYLLQR
LHINFSVFSCSGIDKNGNIWESNELNASLKRKMMEASERAYLLIDSSKFEKTSLIQLADLSKINTIFSDRSLPDNLQKYC
EQHDIMTVL

Sequences:

>Translated_249_residues
MNYRDELILQWVNQQGKASVIELAQHCDISVETIRRDLNKLANKGLLHRTHGGAVSNKTKDLGSFFQTRKHINATAKRHI
AQKALDLLYENAVIGLDASSTSWYFAYLMPDIPCTVVTNSMFNINALVNKSNVKTIVTGGVYSAKYEAFYGPLSEYLLQR
LHINFSVFSCSGIDKNGNIWESNELNASLKRKMMEASERAYLLIDSSKFEKTSLIQLADLSKINTIFSDRSLPDNLQKYC
EQHDIMTVL
>Mature_249_residues
MNYRDELILQWVNQQGKASVIELAQHCDISVETIRRDLNKLANKGLLHRTHGGAVSNKTKDLGSFFQTRKHINATAKRHI
AQKALDLLYENAVIGLDASSTSWYFAYLMPDIPCTVVTNSMFNINALVNKSNVKTIVTGGVYSAKYEAFYGPLSEYLLQR
LHINFSVFSCSGIDKNGNIWESNELNASLKRKMMEASERAYLLIDSSKFEKTSLIQLADLSKINTIFSDRSLPDNLQKYC
EQHDIMTVL

Specific function: Transcriptional activator of the fuc operon

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1789170, Length=209, Percent_Identity=37.3205741626794, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788069, Length=255, Percent_Identity=33.3333333333333, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1789519, Length=238, Percent_Identity=31.9327731092437, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789829, Length=239, Percent_Identity=27.6150627615063, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=31.0483870967742, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787540, Length=231, Percent_Identity=29.8701298701299, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082344, Length=249, Percent_Identity=23.2931726907631, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI226510968, Length=243, Percent_Identity=28.3950617283951, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790753, Length=211, Percent_Identity=26.0663507109005, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790635, Length=242, Percent_Identity=24.3801652892562, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787063, Length=243, Percent_Identity=24.2798353909465, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FUCR_HAEIN (P44780)

Other databases:

- EMBL:   L42023
- PIR:   G64081
- RefSeq:   NP_438773.1
- ProteinModelPortal:   P44780
- SMR:   P44780
- GeneID:   949664
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0615
- TIGR:   HI_0615
- HOGENOM:   HBG694151
- OMA:   HQINITI
- ProtClustDB:   CLSK892374
- BioCyc:   HINF71421:HI_0615-MONOMER
- GO:   GO:0005622
- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00037
- SMART:   SM00420

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR

EC number: NA

Molecular weight: Translated: 28164; Mature: 28164

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS00894 HTH_DEOR_1; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYRDELILQWVNQQGKASVIELAQHCDISVETIRRDLNKLANKGLLHRTHGGAVSNKTK
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCHH
DLGSFFQTRKHINATAKRHIAQKALDLLYENAVIGLDASSTSWYFAYLMPDIPCTVVTNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEECCCCCCEEEECC
MFNINALVNKSNVKTIVTGGVYSAKYEAFYGPLSEYLLQRLHINFSVFSCSGIDKNGNIW
CEEEEEEEECCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHCCEEEEEECCCCCCCCCC
ESNELNASLKRKMMEASERAYLLIDSSKFEKTSLIQLADLSKINTIFSDRSLPDNLQKYC
CCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
EQHDIMTVL
HHCCCEECC
>Mature Secondary Structure
MNYRDELILQWVNQQGKASVIELAQHCDISVETIRRDLNKLANKGLLHRTHGGAVSNKTK
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCHH
DLGSFFQTRKHINATAKRHIAQKALDLLYENAVIGLDASSTSWYFAYLMPDIPCTVVTNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEECCCCCCEEEECC
MFNINALVNKSNVKTIVTGGVYSAKYEAFYGPLSEYLLQRLHINFSVFSCSGIDKNGNIW
CEEEEEEEECCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHCCEEEEEECCCCCCCCCC
ESNELNASLKRKMMEASERAYLLIDSSKFEKTSLIQLADLSKINTIFSDRSLPDNLQKYC
CCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
EQHDIMTVL
HHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800