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The map label for this gene is htpX [H]

Identifier: 148827888

GI number: 148827888

Start: 1265394

End: 1266245

Strand: Direct

Name: htpX [H]

Synonym: CGSHiGG_06915

Alternate gene names: 148827888

Gene position: 1265394-1266245 (Clockwise)

Preceding gene: 148827887

Following gene: 148827890

Centisome position: 67.05

GC content: 41.67

Gene sequence:

>852_bases
ATGATGCGAATTCTTCTTTTCTTGGCAACCAATATGGCTGTAATGCTCGTATTGGGGATTATTTTAAGTGTGACTGGTAT
TGCAGGAAATAGTACTGGCGGCATTTTAATTATGGCTTTGCTATTTGGTTTTGCTGGTTCATTAATTTCCTTATTCCTGT
CTAAAACGATGGCATTACGTTCTGTAGATGGAGAAGTGATTACTCAACCTCGTAATCAAACTGAACGTTGGTTAATTGAT
ACCGTTAGTCGCCAAGCACAGAAAGCGGGTATTCCCATGCCAGACGTGGCAATTTATCATTCACCCGATGTGAATGCTTT
TGCGACAGGTGCAACGAAAAGCAATTCTTTAGTGGCAGTGAGTACGGGATTATTAAACAACATGACGGAGGCTGAAGCTG
AAGCTGTTTTAGCGCACGAAATTTCTCATATTTCCAATGGGGATATGGTGACGATGGCGTTATTGCAAGGCGTATTGAAT
ACTTTCGTGATTTTCTTATCGCGCGTTATTGCAACGGCGGTGGCAAGTTCGCGTAACAATAATGGAGAGGAAACGCGCAG
TTCAGGTATTTATTTCTTGGTTTCTATGGTATTGGAAATGCTCTTTGGTGTGCTTGCGAGTATTATCGCAATGTGGTTCT
CACGCTACCGCGAATTCCGTGCAGATGCTGGTTCAGCAAGTTTAGTAGGCAAAGAAAAAATGATCATGGCATTGCAACGT
TTGCAACAACTTCACGAACCACAAAATCTCGAAGGTTCTTTAAATGCCTTTATGATTAATGGTAAACGCAGTGAACTCTT
TATGAGCCATCCACCACTCGAAAAGCGTATTGAAGCCTTACGCAATCTTTAA

Upstream 100 bases:

>100_bases
GTTTATCTGCTGATAACAAAAATTTTACATTACACCTTGAATTTTTTGTGAATTTTCCCCACAAAGGAAATACTTAACCC
TAACTTTGAGAGAACACATT

Downstream 100 bases:

>100_bases
AAATTATAAAAAATCGACCGCACTTTAATGAGGTCGATGTTTTATTTTCCTCTTTTCACCCAATATTTGAACGGGGGCTT
TTCCACTTCACTTTGCAGTA

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MMRILLFLATNMAVMLVLGIILSVTGIAGNSTGGILIMALLFGFAGSLISLFLSKTMALRSVDGEVITQPRNQTERWLID
TVSRQAQKAGIPMPDVAIYHSPDVNAFATGATKSNSLVAVSTGLLNNMTEAEAEAVLAHEISHISNGDMVTMALLQGVLN
TFVIFLSRVIATAVASSRNNNGEETRSSGIYFLVSMVLEMLFGVLASIIAMWFSRYREFRADAGSASLVGKEKMIMALQR
LQQLHEPQNLEGSLNAFMINGKRSELFMSHPPLEKRIEALRNL

Sequences:

>Translated_283_residues
MMRILLFLATNMAVMLVLGIILSVTGIAGNSTGGILIMALLFGFAGSLISLFLSKTMALRSVDGEVITQPRNQTERWLID
TVSRQAQKAGIPMPDVAIYHSPDVNAFATGATKSNSLVAVSTGLLNNMTEAEAEAVLAHEISHISNGDMVTMALLQGVLN
TFVIFLSRVIATAVASSRNNNGEETRSSGIYFLVSMVLEMLFGVLASIIAMWFSRYREFRADAGSASLVGKEKMIMALQR
LQQLHEPQNLEGSLNAFMINGKRSELFMSHPPLEKRIEALRNL
>Mature_283_residues
MMRILLFLATNMAVMLVLGIILSVTGIAGNSTGGILIMALLFGFAGSLISLFLSKTMALRSVDGEVITQPRNQTERWLID
TVSRQAQKAGIPMPDVAIYHSPDVNAFATGATKSNSLVAVSTGLLNNMTEAEAEAVLAHEISHISNGDMVTMALLQGVLN
TFVIFLSRVIATAVASSRNNNGEETRSSGIYFLVSMVLEMLFGVLASIIAMWFSRYREFRADAGSASLVGKEKMIMALQR
LQQLHEPQNLEGSLNAFMINGKRSELFMSHPPLEKRIEALRNL

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=289, Percent_Identity=65.3979238754325, Blast_Score=375, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 30781; Mature: 30781

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRILLFLATNMAVMLVLGIILSVTGIAGNSTGGILIMALLFGFAGSLISLFLSKTMALR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVDGEVITQPRNQTERWLIDTVSRQAQKAGIPMPDVAIYHSPDVNAFATGATKSNSLVAV
HCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCEEEE
STGLLNNMTEAEAEAVLAHEISHISNGDMVTMALLQGVLNTFVIFLSRVIATAVASSRNN
EHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NGEETRSSGIYFLVSMVLEMLFGVLASIIAMWFSRYREFRADAGSASLVGKEKMIMALQR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LQQLHEPQNLEGSLNAFMINGKRSELFMSHPPLEKRIEALRNL
HHHHCCCCCCCCCCEEEEECCCCCHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MMRILLFLATNMAVMLVLGIILSVTGIAGNSTGGILIMALLFGFAGSLISLFLSKTMALR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVDGEVITQPRNQTERWLIDTVSRQAQKAGIPMPDVAIYHSPDVNAFATGATKSNSLVAV
HCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCEEEE
STGLLNNMTEAEAEAVLAHEISHISNGDMVTMALLQGVLNTFVIFLSRVIATAVASSRNN
EHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NGEETRSSGIYFLVSMVLEMLFGVLASIIAMWFSRYREFRADAGSASLVGKEKMIMALQR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LQQLHEPQNLEGSLNAFMINGKRSELFMSHPPLEKRIEALRNL
HHHHCCCCCCCCCCEEEEECCCCCHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA