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The map label for this gene is clpX [H]

Identifier: 148827883

GI number: 148827883

Start: 1261577

End: 1262812

Strand: Direct

Name: clpX [H]

Synonym: CGSHiGG_06890

Alternate gene names: 148827883

Gene position: 1261577-1262812 (Clockwise)

Preceding gene: 148827882

Following gene: 148827884

Centisome position: 66.85

GC content: 36.57

Gene sequence:

>1236_bases
ATGACAGACAAAGATAAAGATTTGCACTGCTCTTTTTGCGGAAAAGAAAAAGGCGAAGTAGATAAATTAATTGCTGGCAC
AGGCGGTTATATTTGTAATGAATGTATTGAACTTTGTCACTCAATGCTTGAAGAAAGTAATGATGAAAACCTAGAGGAAA
GTGCGGTCGAAAATAAAGATAAATTGCCAACGCCTCACGAAATTCGCGCCCATCTGGATGATTATGTTATTGGTCAAGAT
TATGCGAAAAAAGTGCTTTCTGTGGCAGTTTATAATCATTATAAACGCTTGCGAACTAACTATGAAAGCAATGATGTAGA
GCTTGGCAAAAGTAATATTTTACTTATAGGCCCTACGGGTAGCGGAAAAACGTTACTTGCGCAAACATTAGCTCGTCGTT
TAAATGTACCCTTTGCGATGGCGGATGCAACCACATTAACGGAAGCTGGTTATGTGGGAGAAGATGTAGAGAATGTATTA
CAGAAACTTTTGCAAAATTGTGAATACGATACTGAAAAAGCAGAGAAAGGCATTATTTATATTGATGAAATTGATAAAAT
TAGCCGTAAATCGGAAGGCGCATCAATTACTCGAGATGTTTCAGGGGAGGGGGTGCAACAGGCTTTATTAAAACTTATTG
AAGGTACAATCGCTTCAATTCCACCTCAAGGCGGTCGTAAACATCCACAACAAGAAATGGTAAAATTGGATACGTCTAAA
ATTCTCTTTATTTGTGGCGGTGCATTTGCAGGATTAGATAAAATTATTGATAAACGCACTCAAACCAGTACGAGTATTGG
TTTTAATGCCAAAGTTGAAAAAGATGAAAAACAACAATCTCTTTCTGAATTATTCCGTCAAGTTGAACCTGATGATTTGA
TGAAATTTGGTTTAATTCCAGAATTTATCGGACGTTTGCCAATGATTGCCCCATTAAGTGAATTAGACGAAGATGCGCTG
ATACAAATTCTCACAAAACCAAAAAACGCATTAATTAAACAATATCAAGCCTTATTTGGATTGGAAAAAGTAGAATTGGA
TTTCACACCAGAAGCATTAAAAGCAATGGCGAAAAAAGCACTTGAAAGAAAAACGGGTGCGCGTGGCTTACGTTCTATCG
TAGAAGCAGTGTTGTTAGATACAATGTATGATCTACCGTCTCTTGAGAATTTACAAAAAGTTATCGTTGATGAATCGACA
ATTGTAGATAATCTTGCGCCCAAATTAGAATATTAG

Upstream 100 bases:

>100_bases
TATTGAGAAAGATACCGACCGCGATAATTTTATGTCAGCGGAAGAAGCACAAGCGTATGGTTTGGTGGATGAAGTCTTAG
TTAAACGTTAAGGGTATACA

Downstream 100 bases:

>100_bases
ATTTAATCGCAAAAGTGCGGTTGTTTTCGCCAGATTTTCTATGTTGATGCTTATTTTCAATAGGCAAGGCGAAAAGAAAA
TGCTACAATCGCACGTTCTT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTDKDKDLHCSFCGKEKGEVDKLIAGTGGYICNECIELCHSMLEESNDENLEESAVENKDKLPTPHEIRAHLDDYVIGQD
YAKKVLSVAVYNHYKRLRTNYESNDVELGKSNILLIGPTGSGKTLLAQTLARRLNVPFAMADATTLTEAGYVGEDVENVL
QKLLQNCEYDTEKAEKGIIYIDEIDKISRKSEGASITRDVSGEGVQQALLKLIEGTIASIPPQGGRKHPQQEMVKLDTSK
ILFICGGAFAGLDKIIDKRTQTSTSIGFNAKVEKDEKQQSLSELFRQVEPDDLMKFGLIPEFIGRLPMIAPLSELDEDAL
IQILTKPKNALIKQYQALFGLEKVELDFTPEALKAMAKKALERKTGARGLRSIVEAVLLDTMYDLPSLENLQKVIVDEST
IVDNLAPKLEY

Sequences:

>Translated_411_residues
MTDKDKDLHCSFCGKEKGEVDKLIAGTGGYICNECIELCHSMLEESNDENLEESAVENKDKLPTPHEIRAHLDDYVIGQD
YAKKVLSVAVYNHYKRLRTNYESNDVELGKSNILLIGPTGSGKTLLAQTLARRLNVPFAMADATTLTEAGYVGEDVENVL
QKLLQNCEYDTEKAEKGIIYIDEIDKISRKSEGASITRDVSGEGVQQALLKLIEGTIASIPPQGGRKHPQQEMVKLDTSK
ILFICGGAFAGLDKIIDKRTQTSTSIGFNAKVEKDEKQQSLSELFRQVEPDDLMKFGLIPEFIGRLPMIAPLSELDEDAL
IQILTKPKNALIKQYQALFGLEKVELDFTPEALKAMAKKALERKTGARGLRSIVEAVLLDTMYDLPSLENLQKVIVDEST
IVDNLAPKLEY
>Mature_410_residues
TDKDKDLHCSFCGKEKGEVDKLIAGTGGYICNECIELCHSMLEESNDENLEESAVENKDKLPTPHEIRAHLDDYVIGQDY
AKKVLSVAVYNHYKRLRTNYESNDVELGKSNILLIGPTGSGKTLLAQTLARRLNVPFAMADATTLTEAGYVGEDVENVLQ
KLLQNCEYDTEKAEKGIIYIDEIDKISRKSEGASITRDVSGEGVQQALLKLIEGTIASIPPQGGRKHPQQEMVKLDTSKI
LFICGGAFAGLDKIIDKRTQTSTSIGFNAKVEKDEKQQSLSELFRQVEPDDLMKFGLIPEFIGRLPMIAPLSELDEDALI
QILTKPKNALIKQYQALFGLEKVELDFTPEALKAMAKKALERKTGARGLRSIVEAVLLDTMYDLPSLENLQKVIVDESTI
VDNLAPKLEY

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=304, Percent_Identity=53.6184210526316, Blast_Score=314, Evalue=1e-85,
Organism=Escherichia coli, GI1786642, Length=416, Percent_Identity=69.9519230769231, Blast_Score=588, Evalue=1e-169,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=45, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=309, Percent_Identity=45.6310679611651, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=309, Percent_Identity=45.6310679611651, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=391, Percent_Identity=38.1074168797954, Blast_Score=251, Evalue=7e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=260, Percent_Identity=39.6153846153846, Blast_Score=167, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=425, Percent_Identity=43.0588235294118, Blast_Score=287, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24648291, Length=299, Percent_Identity=47.8260869565217, Blast_Score=294, Evalue=9e-80,
Organism=Drosophila melanogaster, GI24648289, Length=299, Percent_Identity=47.8260869565217, Blast_Score=293, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 45611; Mature: 45480

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKDKDLHCSFCGKEKGEVDKLIAGTGGYICNECIELCHSMLEESNDENLEESAVENKD
CCCCCCCCEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC
KLPTPHEIRAHLDDYVIGQDYAKKVLSVAVYNHYKRLRTNYESNDVELGKSNILLIGPTG
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEECCC
SGKTLLAQTLARRLNVPFAMADATTLTEAGYVGEDVENVLQKLLQNCEYDTEKAEKGIIY
CCHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEE
IDEIDKISRKSEGASITRDVSGEGVQQALLKLIEGTIASIPPQGGRKHPQQEMVKLDTSK
EECHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCC
ILFICGGAFAGLDKIIDKRTQTSTSIGFNAKVEKDEKQQSLSELFRQVEPDDLMKFGLIP
EEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCHH
EFIGRLPMIAPLSELDEDALIQILTKPKNALIKQYQALFGLEKVELDFTPEALKAMAKKA
HHHCCCCCCCCHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHH
LERKTGARGLRSIVEAVLLDTMYDLPSLENLQKVIVDESTIVDNLAPKLEY
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDKDKDLHCSFCGKEKGEVDKLIAGTGGYICNECIELCHSMLEESNDENLEESAVENKD
CCCCCCCEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC
KLPTPHEIRAHLDDYVIGQDYAKKVLSVAVYNHYKRLRTNYESNDVELGKSNILLIGPTG
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEECCC
SGKTLLAQTLARRLNVPFAMADATTLTEAGYVGEDVENVLQKLLQNCEYDTEKAEKGIIY
CCHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEE
IDEIDKISRKSEGASITRDVSGEGVQQALLKLIEGTIASIPPQGGRKHPQQEMVKLDTSK
EECHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCC
ILFICGGAFAGLDKIIDKRTQTSTSIGFNAKVEKDEKQQSLSELFRQVEPDDLMKFGLIP
EEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCHH
EFIGRLPMIAPLSELDEDALIQILTKPKNALIKQYQALFGLEKVELDFTPEALKAMAKKA
HHHCCCCCCCCHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHH
LERKTGARGLRSIVEAVLLDTMYDLPSLENLQKVIVDESTIVDNLAPKLEY
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]