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The map label for this gene is glpA [H]

Identifier: 148827860

GI number: 148827860

Start: 1226195

End: 1227637

Strand: Direct

Name: glpA [H]

Synonym: CGSHiGG_06730

Alternate gene names: 148827860

Gene position: 1226195-1227637 (Clockwise)

Preceding gene: 148827857

Following gene: 148827861

Centisome position: 64.97

GC content: 41.58

Gene sequence:

>1443_bases
ATGTTTGGACCATTCAAACCCGCTCCGCATATTGCGGAACTTCCAGCGGAAAAAATTGATTCCACGTATAAACGCTTACG
TTGGCAAGTGTTTGCAGGGATCTTCTTCGGTTATGCTGCATATTATTTTGTGCGTGCAAACTTTGACTTAGCACAACCAG
GTTTAATTCAAGCTGGCTTGTACTCAAAAGCGGAACTAGGTGTTATCGGCTCAGCGGCTGGTCTTGCTTACGGTTTATCA
AAATTCGTTATGGCAAGTATGTCTGACCGTTCTAACCCTCGTGTATTCTTACCATTTGGTTTATTGCTCTCTGGTTTATG
TATGACCTTAATGGGTCTATTCCCATGGGCAACCTCTGGCATCGCTATCATGTGGGCGATGATCTTCTTAAATGGTTGGT
TCCAAGGTATGGGTTGGCCTCCATGTGGTCGTACAATGGTACACTGGTGGTCTAAATCTGAACGCGGTACTATCGTGTCA
ATTTGGAATACTGCGCACAATATCGGTGGTATGGTGCCTGGTGCAATGGTGTTATTAGCTAGTGCAATTTTCTTCAGCAT
TCACGGTATTGAAGCGCAAGCAAAAGACATCTGGCAACAATCTTTATACTACCCTGGTATTGCAGCAATGATCTGTGCAA
TTCCTGTGTACTTCGTGATGCGTGATACTCCACAATCTTGTGGTTTACCATCAATCGAAAAATGGCGTAATGACTACCCA
GATGACTATAACGAAAAAACTTACGAAAACGATTTAACTGCAAAAGAAATCTTCGTAACTTATGTATTAAAAAACAAATT
GTTATGGTATATCGCGATTGCTAACGTGTTCGTCTATTTAATCCGCTACGGTGTATTAAAATGGTCTCCAGTTTACTTGA
GTGAAGTGAAACACTTCAACATCAAAGGTACTGCATGGGCATACACAATCTATGAATTAGCAGCGGTTCCAGGTACGTTA
TTATGTGGTTGGGTATCAGATAAAGTATTCAAAGGTAAACGTGGTTTAACTGGTTTCATCTTCATGATCTTAACCACTGC
AGCAGTTGTTGCATACTGGATGAATCCTGCGACACCAGAAGCTGAATTAGCGAACTACAGCGCATGGTATCAAAACCCAT
ACCAATTAACTGACTTCGTATTAATGACTTTAATCGGTTTCTTAATCTATGGTCCTGTAATGTTAATCGGTTTACATGCG
CTTGAGTTAGCACCGAAAAAAGCAGCAGGTACTGCAGCAGGTTTCACCGGTTTATTCGGTTACTTAGGTGGTACAGTTTC
TGCATCAGCAGTTATCGGTTGGGCTGCTCAACATTATGGATGGGACGGTGGTTTCTTCGTAATGATCGGCGGTGGTGTAT
TAGCAGTGTTATTACTCTTAATCGTAATGGTTGAAGAAGGAAAACACAAAGCGAAATTAGGCGATACTTACGGTACTAAA
TAA

Upstream 100 bases:

>100_bases
ACTTTCTTATTTTTTATTTTCTTTTATGATTCACAAATCCCTTACTGTTTCAAAAGGGGAAATTTAGATGACACATAATT
AAAAAGTTGGAGAAAAAATT

Downstream 100 bases:

>100_bases
TTAGCTTAAAAAAGGCGGTGGGCAAATTGCTTAGTCGCCTTTTTTGTAACTAAAATCTAAAAACCTCATAAAAATTTACC
GCACTCTCAAGGAGAAAATA

Product: sn-glycerol-3-phosphate dehydrogenase subunit A

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MFGPFKPAPHIAELPAEKIDSTYKRLRWQVFAGIFFGYAAYYFVRANFDLAQPGLIQAGLYSKAELGVIGSAAGLAYGLS
KFVMASMSDRSNPRVFLPFGLLLSGLCMTLMGLFPWATSGIAIMWAMIFLNGWFQGMGWPPCGRTMVHWWSKSERGTIVS
IWNTAHNIGGMVPGAMVLLASAIFFSIHGIEAQAKDIWQQSLYYPGIAAMICAIPVYFVMRDTPQSCGLPSIEKWRNDYP
DDYNEKTYENDLTAKEIFVTYVLKNKLLWYIAIANVFVYLIRYGVLKWSPVYLSEVKHFNIKGTAWAYTIYELAAVPGTL
LCGWVSDKVFKGKRGLTGFIFMILTTAAVVAYWMNPATPEAELANYSAWYQNPYQLTDFVLMTLIGFLIYGPVMLIGLHA
LELAPKKAAGTAAGFTGLFGYLGGTVSASAVIGWAAQHYGWDGGFFVMIGGGVLAVLLLLIVMVEEGKHKAKLGDTYGTK

Sequences:

>Translated_480_residues
MFGPFKPAPHIAELPAEKIDSTYKRLRWQVFAGIFFGYAAYYFVRANFDLAQPGLIQAGLYSKAELGVIGSAAGLAYGLS
KFVMASMSDRSNPRVFLPFGLLLSGLCMTLMGLFPWATSGIAIMWAMIFLNGWFQGMGWPPCGRTMVHWWSKSERGTIVS
IWNTAHNIGGMVPGAMVLLASAIFFSIHGIEAQAKDIWQQSLYYPGIAAMICAIPVYFVMRDTPQSCGLPSIEKWRNDYP
DDYNEKTYENDLTAKEIFVTYVLKNKLLWYIAIANVFVYLIRYGVLKWSPVYLSEVKHFNIKGTAWAYTIYELAAVPGTL
LCGWVSDKVFKGKRGLTGFIFMILTTAAVVAYWMNPATPEAELANYSAWYQNPYQLTDFVLMTLIGFLIYGPVMLIGLHA
LELAPKKAAGTAAGFTGLFGYLGGTVSASAVIGWAAQHYGWDGGFFVMIGGGVLAVLLLLIVMVEEGKHKAKLGDTYGTK
>Mature_480_residues
MFGPFKPAPHIAELPAEKIDSTYKRLRWQVFAGIFFGYAAYYFVRANFDLAQPGLIQAGLYSKAELGVIGSAAGLAYGLS
KFVMASMSDRSNPRVFLPFGLLLSGLCMTLMGLFPWATSGIAIMWAMIFLNGWFQGMGWPPCGRTMVHWWSKSERGTIVS
IWNTAHNIGGMVPGAMVLLASAIFFSIHGIEAQAKDIWQQSLYYPGIAAMICAIPVYFVMRDTPQSCGLPSIEKWRNDYP
DDYNEKTYENDLTAKEIFVTYVLKNKLLWYIAIANVFVYLIRYGVLKWSPVYLSEVKHFNIKGTAWAYTIYELAAVPGTL
LCGWVSDKVFKGKRGLTGFIFMILTTAAVVAYWMNPATPEAELANYSAWYQNPYQLTDFVLMTLIGFLIYGPVMLIGLHA
LELAPKKAAGTAAGFTGLFGYLGGTVSASAVIGWAAQHYGWDGGFFVMIGGGVLAVLLLLIVMVEEGKHKAKLGDTYGTK

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219543, Length=478, Percent_Identity=26.9874476987448, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI256219598, Length=461, Percent_Identity=26.6811279826464, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI4503847, Length=461, Percent_Identity=26.6811279826464, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI256219483, Length=461, Percent_Identity=26.6811279826464, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI256219564, Length=392, Percent_Identity=24.4897959183673, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI223717983, Length=431, Percent_Identity=24.5939675174014, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI38093649, Length=431, Percent_Identity=24.5939675174014, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1788573, Length=479, Percent_Identity=60.9603340292276, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI87082310, Length=464, Percent_Identity=35.3448275862069, Blast_Score=254, Evalue=8e-69,
Organism=Escherichia coli, GI2367259, Length=466, Percent_Identity=31.3304721030043, Blast_Score=200, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI133930953, Length=484, Percent_Identity=23.1404958677686, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17542316, Length=472, Percent_Identity=21.3983050847458, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI133901854, Length=473, Percent_Identity=24.1014799154334, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI133901856, Length=470, Percent_Identity=23.6170212765957, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17564204, Length=426, Percent_Identity=22.7699530516432, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564202, Length=415, Percent_Identity=22.6506024096386, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24656866, Length=502, Percent_Identity=21.3147410358566, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI45550478, Length=502, Percent_Identity=21.3147410358566, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24656861, Length=509, Percent_Identity=21.2180746561886, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53029; Mature: 53029

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGPFKPAPHIAELPAEKIDSTYKRLRWQVFAGIFFGYAAYYFVRANFDLAQPGLIQAGL
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEECCC
YSKAELGVIGSAAGLAYGLSKFVMASMSDRSNPRVFLPFGLLLSGLCMTLMGLFPWATSG
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCH
IAIMWAMIFLNGWFQGMGWPPCGRTMVHWWSKSERGTIVSIWNTAHNIGGMVPGAMVLLA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCEEEEECCHHHHCCCCHHHHHHHH
SAIFFSIHGIEAQAKDIWQQSLYYPGIAAMICAIPVYFVMRDTPQSCGLPSIEKWRNDYP
HHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCC
DDYNEKTYENDLTAKEIFVTYVLKNKLLWYIAIANVFVYLIRYGVLKWSPVYLSEVKHFN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
IKGTAWAYTIYELAAVPGTLLCGWVSDKVFKGKRGLTGFIFMILTTAAVVAYWMNPATPE
CCCCHHHHHHHHHHHCCHHHEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
AELANYSAWYQNPYQLTDFVLMTLIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFG
HHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
YLGGTVSASAVIGWAAQHYGWDGGFFVMIGGGVLAVLLLLIVMVEEGKHKAKLGDTYGTK
HHCCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHCCCCCCCC
>Mature Secondary Structure
MFGPFKPAPHIAELPAEKIDSTYKRLRWQVFAGIFFGYAAYYFVRANFDLAQPGLIQAGL
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEECCC
YSKAELGVIGSAAGLAYGLSKFVMASMSDRSNPRVFLPFGLLLSGLCMTLMGLFPWATSG
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCH
IAIMWAMIFLNGWFQGMGWPPCGRTMVHWWSKSERGTIVSIWNTAHNIGGMVPGAMVLLA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCEEEEECCHHHHCCCCHHHHHHHH
SAIFFSIHGIEAQAKDIWQQSLYYPGIAAMICAIPVYFVMRDTPQSCGLPSIEKWRNDYP
HHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCC
DDYNEKTYENDLTAKEIFVTYVLKNKLLWYIAIANVFVYLIRYGVLKWSPVYLSEVKHFN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
IKGTAWAYTIYELAAVPGTLLCGWVSDKVFKGKRGLTGFIFMILTTAAVVAYWMNPATPE
CCCCHHHHHHHHHHHCCHHHEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
AELANYSAWYQNPYQLTDFVLMTLIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFG
HHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
YLGGTVSASAVIGWAAQHYGWDGGFFVMIGGGVLAVLLLLIVMVEEGKHKAKLGDTYGTK
HHCCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 9714837 [H]