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The map label for this gene is gpt1 [H]

Identifier: 148827850

GI number: 148827850

Start: 1212840

End: 1213307

Strand: Reverse

Name: gpt1 [H]

Synonym: CGSHiGG_06650

Alternate gene names: 148827850

Gene position: 1213307-1212840 (Counterclockwise)

Preceding gene: 148827852

Following gene: 148827848

Centisome position: 64.29

GC content: 42.09

Gene sequence:

>468_bases
ATGAGCGAAAAATATGTGGTGACCTGGGATATGTTTCAAATGCATGCCCGCAAATTATCAGAACGTTTACTTCCAGCTTC
CCAATGGAAAGGTATTATTGCGGTAAGTCGCGGTGGTTTGTTTCCAGCGGCTGTGTTGGCTAGAGAATTAGGTCTTCGCC
ATATTGAAACCGTTTGTATCGCAAGTTATCACGATCATAACAATCAAGGTGAACTACAAGTTCTTCATGCCGCCCAAGTG
CCAAATGGCGGCGAAGGGTTTATCGTGGTAGATGATTTAGTTGATACGGGTAATACTGCGCGTGCGATTCGTCAAATGTA
CCCTAATGCAAAATTTGTCACTGTATTTGCAAAACCTGCAGGTGCGGAATTAGTGGATGATTACGTAATTGATATTCCAC
AAAATACTTGGATTGAGCAACCTTGGGATTTAGGTTTAACCTTTGTTCCACCTCTCTCTAGAAAATAA

Upstream 100 bases:

>100_bases
TTTTACTGAAAATATTTACGAAATAATAGCATAAAACGCCATTTCGGGTTATCCTTACGCAATTTTTTATTTCTCGATAA
ATTTAAACTAAGGTGCAATT

Downstream 100 bases:

>100_bases
TTTTTATACAAAAAAGTGCGGTTAAAATAAAAGAATTTTTAATCGCACTTTCTTTCATTTTATCGTTTTTCCTAATTTTT
CACGGTAAACAGGTTAAAAT

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase 1; XGPRT 1 [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MSEKYVVTWDMFQMHARKLSERLLPASQWKGIIAVSRGGLFPAAVLARELGLRHIETVCIASYHDHNNQGELQVLHAAQV
PNGGEGFIVVDDLVDTGNTARAIRQMYPNAKFVTVFAKPAGAELVDDYVIDIPQNTWIEQPWDLGLTFVPPLSRK

Sequences:

>Translated_155_residues
MSEKYVVTWDMFQMHARKLSERLLPASQWKGIIAVSRGGLFPAAVLARELGLRHIETVCIASYHDHNNQGELQVLHAAQV
PNGGEGFIVVDDLVDTGNTARAIRQMYPNAKFVTVFAKPAGAELVDDYVIDIPQNTWIEQPWDLGLTFVPPLSRK
>Mature_154_residues
SEKYVVTWDMFQMHARKLSERLLPASQWKGIIAVSRGGLFPAAVLARELGLRHIETVCIASYHDHNNQGELQVLHAAQVP
NGGEGFIVVDDLVDTGNTARAIRQMYPNAKFVTVFAKPAGAELVDDYVIDIPQNTWIEQPWDLGLTFVPPLSRK

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=155, Percent_Identity=72.258064516129, Blast_Score=241, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 17297; Mature: 17166

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKYVVTWDMFQMHARKLSERLLPASQWKGIIAVSRGGLFPAAVLARELGLRHIETVCI
CCCCEEEEHHHHHHHHHHHHHHCCCHHHCCCEEEEECCCCCHHHHHHHHHCHHHHHHHEE
ASYHDHNNQGELQVLHAAQVPNGGEGFIVVDDLVDTGNTARAIRQMYPNAKFVTVFAKPA
EEECCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCC
GAELVDDYVIDIPQNTWIEQPWDLGLTFVPPLSRK
CCHHHCCEEEECCCCCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
SEKYVVTWDMFQMHARKLSERLLPASQWKGIIAVSRGGLFPAAVLARELGLRHIETVCI
CCCEEEEHHHHHHHHHHHHHHCCCHHHCCCEEEEECCCCCHHHHHHHHHCHHHHHHHEE
ASYHDHNNQGELQVLHAAQVPNGGEGFIVVDDLVDTGNTARAIRQMYPNAKFVTVFAKPA
EEECCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCC
GAELVDDYVIDIPQNTWIEQPWDLGLTFVPPLSRK
CCHHHCCEEEECCCCCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA