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The map label for this gene is hypB [H]

Identifier: 148824047

GI number: 148824047

Start: 3179506

End: 3179838

Strand: Direct

Name: hypB [H]

Synonym: TBFG_12872

Alternate gene names: 148824047

Gene position: 3179506-3179838 (Clockwise)

Preceding gene: 148824046

Following gene: 148824054

Centisome position: 71.86

GC content: 64.26

Gene sequence:

>333_bases
GTGTTGGAAAAGATCTTCGCCGAGAACGATGTCCGCGCGAACGTCAACCGGGCGGCGTTTGAGAACAACGGGATCCGCGC
GCTGGACCTGATGAGCTCACCGGGGTCGGGGAAGACGACCGTGCTGGGCGCCGCGCTCGACGAGCACGCCGACCAATTCG
CAATCGGCGTTATCGAAGGCGACATCACCACCGACCTGGACGCGGCCAATGGCCGCGGCACCCAGGTGTCGCTGCTGAAC
AACCAGCATGGCTTTTGCGCCGAATGCCACCTCGACGCACCTATGGTCAACCGCGCCCTAGCTGGTGCGCCCGACGGAGT
TCGACGTCGGTAA

Upstream 100 bases:

>100_bases
AGCGGTGGACCCCGGCGCCCGACCGCACAACTTGACCTCGGGCGATCAACCCTAGGGCGGTGCCGCCGGAATCGAGACGG
TAGCCAAGCGAGCGGTCGAC

Downstream 100 bases:

>100_bases
GCGCCAAGGCGATGGTCTCCTCGGTCACCGAGGGCAAGGACAAGCCGCTGATGTACCCGGCGACGTTCCGCTCGAGGGAT
GTAGTGCTGCTCGACAAGAT

Product: Ni2+-binding GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MLEKIFAENDVRANVNRAAFENNGIRALDLMSSPGSGKTTVLGAALDEHADQFAIGVIEGDITTDLDAANGRGTQVSLLN
NQHGFCAECHLDAPMVNRALAGAPDGVRRR

Sequences:

>Translated_110_residues
MLEKIFAENDVRANVNRAAFENNGIRALDLMSSPGSGKTTVLGAALDEHADQFAIGVIEGDITTDLDAANGRGTQVSLLN
NQHGFCAECHLDAPMVNRALAGAPDGVRRR
>Mature_110_residues
MLEKIFAENDVRANVNRAAFENNGIRALDLMSSPGSGKTTVLGAALDEHADQFAIGVIEGDITTDLDAANGRGTQVSLLN
NQHGFCAECHLDAPMVNRALAGAPDGVRRR

Specific function: May work in the mobilization of nickel into hydrogenase enzyme. Binds 9 nickel ions per molecule [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 11647; Mature: 11647

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKIFAENDVRANVNRAAFENNGIRALDLMSSPGSGKTTVLGAALDEHADQFAIGVIEG
CCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCEEEEECHHHHCCCEEEEEEEEC
DITTDLDAANGRGTQVSLLNNQHGFCAECHLDAPMVNRALAGAPDGVRRR
CCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLEKIFAENDVRANVNRAAFENNGIRALDLMSSPGSGKTTVLGAALDEHADQFAIGVIEG
CCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCEEEEECHHHHCCCEEEEEEEEC
DITTDLDAANGRGTQVSLLNNQHGFCAECHLDAPMVNRALAGAPDGVRRR
CCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8305450; 12597275 [H]