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The map label for this gene is eccB2

Identifier: 148663762

GI number: 148663762

Start: 4388899

End: 4390386

Strand: Reverse

Name: eccB2

Synonym: MRA_3934

Alternate gene names: 148663762

Gene position: 4390386-4388899 (Counterclockwise)

Preceding gene: 148663763

Following gene: 148663761

Centisome position: 99.33

GC content: 69.62

Gene sequence:

>1488_bases
ATGCCGCTGAGTTTGTCCAACCGCGACCAAAATTCCGGTCATCTGTTCTACAACCGGCGGCTGCGGGCGGCGACCACCCG
GTTCTCGGTGCGCATGAAACACGACGACCGCAAGCAGACCGCCGCGCTGGCGTTGTCGATGGTGTTGGTGGCCATTGCCG
CCGGATGGATGATGCTGCTCAACGTGCTCAAGCCCACCGGCATTGTGGGTGACTCGGCGATCATCGGGGACCGCGACTCC
GGGGCACTCTACGCGCGCATCGACGGCCGGTTGTATCCGGCGCTGAACTTGACGTCCGCGCGGCTGGCCACCGGCACGGC
GGGGCAGCCGACATGGGTCAAGCCCGCCGAGATCGCCAAGTATCCGACCGGGCCGCTGGTCGGCATCCCGGGCGCACCCG
CGGCCATGCCGGTGAACCGGGGCGCGGTCTCGGCGTGGGCGGTGTGCGACACGGCGGGACGCCCGCGCAGCGCGGACAAG
CCGGTGGTCACCTCGATCGCGGGCCCGATCACCGGCGGTGGCCGCGCCACACACCTGCGCGACGACGCCGGGCTGCTGGT
GACTTTCGACGGCAGCACCTACGTGATCTGGGGTGGCAAACGCTCACAGATCGATCCGACCAACAGGGCGGTCACCTTGA
GCTTGGGGCTCGACCCCGGCGTGACATCACCAATACAGATCTCACGGGCGCTCTTCGACGGGCTGCCCGCGACCGAGCCG
CTGCGGGTGCCAGCGGTGCCCGAGGCGGGCACCCCGTCGACGTGGGTGCCGGGCGCTCGGGTGGGATCGGTGTTGCAGGC
CCAAACCGCCGGCGGGGGCAGCCAGTTCTATGTGCTGCTGCCCGACGGGGTGCAAAAGATCAGCAGCTTCGTGGCCGATC
TGCTGCGCAGCGCGAACTCCTACGGGGCGGCGGCGCCGCGGGTGGTGACCCCCGATGTGCTGGTCCACACACCGCAGGTG
ACCTCGCTGCCGGTGGAGTACTACCCGGCCGGGCGGCTGAATTTCGTTGACACCGCGGCGGATCCGACCACCTGCGTGTC
GTGGGAGAAGGCGTCGACGGATCCACAGGCCCGGGTCGCGGTCTACAACGGGCGGGGGCTTCCGGTGCCCCCGTCGATGG
ACAGCCGGATCGTGCGGCTGGTACGCGATGACCGCGCCCCGGCGTCGGTGGTGGCCACCCAGGTGCTGGTGTTGCCCGGC
GCGGCCAACTTCGTGACATCGACCAGCGGTGTGATCACCGCCGAGTCGCGCGAATCGTTGTTCTGGGTGTCCGGCAATGG
GGTGCGATTCGGGATCGCCAACGACGAGGCGACGCTGCGGGCGCTGGGCCTGGATCCGGGTGCGGCCGTGCAGGCGCCGT
GGCCGTTGCTGCGGACTTTTGCTGCGGGACCGGCTCTGTCGCGGGATGCGGCACTCTTGGCTCGCGATACTGTGCCCACC
CTCGGCCAGGTGGCCATTGTGACGACAACGGCGAAGGCGGGCGCCTAG

Upstream 100 bases:

>100_bases
ACTACGCGAGAGGCCACTACGGGGTGGCCGCCGACGCATCGAATCTGGCCGATCTGATCCAGCAGGCCGATCCTCGCCGC
AGCCCCAGGGGGTATTGAGA

Downstream 100 bases:

>100_bases
ATGTCCAAGAAAGCGTTTCCCATCAACCGCGTCAACATCGACCCGCCGAAACCCGTTCGGGTGGCTCCGAATCCGCCGAT
AGCTCTGCCGGAGCGCGAGC

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component B2; Type VII secretion system protein eccB2; T7SS protein eccB2

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MPLSLSNRDQNSGHLFYNRRLRAATTRFSVRMKHDDRKQTAALALSMVLVAIAAGWMMLLNVLKPTGIVGDSAIIGDRDS
GALYARIDGRLYPALNLTSARLATGTAGQPTWVKPAEIAKYPTGPLVGIPGAPAAMPVNRGAVSAWAVCDTAGRPRSADK
PVVTSIAGPITGGGRATHLRDDAGLLVTFDGSTYVIWGGKRSQIDPTNRAVTLSLGLDPGVTSPIQISRALFDGLPATEP
LRVPAVPEAGTPSTWVPGARVGSVLQAQTAGGGSQFYVLLPDGVQKISSFVADLLRSANSYGAAAPRVVTPDVLVHTPQV
TSLPVEYYPAGRLNFVDTAADPTTCVSWEKASTDPQARVAVYNGRGLPVPPSMDSRIVRLVRDDRAPASVVATQVLVLPG
AANFVTSTSGVITAESRESLFWVSGNGVRFGIANDEATLRALGLDPGAAVQAPWPLLRTFAAGPALSRDAALLARDTVPT
LGQVAIVTTTAKAGA

Sequences:

>Translated_495_residues
MPLSLSNRDQNSGHLFYNRRLRAATTRFSVRMKHDDRKQTAALALSMVLVAIAAGWMMLLNVLKPTGIVGDSAIIGDRDS
GALYARIDGRLYPALNLTSARLATGTAGQPTWVKPAEIAKYPTGPLVGIPGAPAAMPVNRGAVSAWAVCDTAGRPRSADK
PVVTSIAGPITGGGRATHLRDDAGLLVTFDGSTYVIWGGKRSQIDPTNRAVTLSLGLDPGVTSPIQISRALFDGLPATEP
LRVPAVPEAGTPSTWVPGARVGSVLQAQTAGGGSQFYVLLPDGVQKISSFVADLLRSANSYGAAAPRVVTPDVLVHTPQV
TSLPVEYYPAGRLNFVDTAADPTTCVSWEKASTDPQARVAVYNGRGLPVPPSMDSRIVRLVRDDRAPASVVATQVLVLPG
AANFVTSTSGVITAESRESLFWVSGNGVRFGIANDEATLRALGLDPGAAVQAPWPLLRTFAAGPALSRDAALLARDTVPT
LGQVAIVTTTAKAGA
>Mature_494_residues
PLSLSNRDQNSGHLFYNRRLRAATTRFSVRMKHDDRKQTAALALSMVLVAIAAGWMMLLNVLKPTGIVGDSAIIGDRDSG
ALYARIDGRLYPALNLTSARLATGTAGQPTWVKPAEIAKYPTGPLVGIPGAPAAMPVNRGAVSAWAVCDTAGRPRSADKP
VVTSIAGPITGGGRATHLRDDAGLLVTFDGSTYVIWGGKRSQIDPTNRAVTLSLGLDPGVTSPIQISRALFDGLPATEPL
RVPAVPEAGTPSTWVPGARVGSVLQAQTAGGGSQFYVLLPDGVQKISSFVADLLRSANSYGAAAPRVVTPDVLVHTPQVT
SLPVEYYPAGRLNFVDTAADPTTCVSWEKASTDPQARVAVYNGRGLPVPPSMDSRIVRLVRDDRAPASVVATQVLVLPGA
ANFVTSTSGVITAESRESLFWVSGNGVRFGIANDEATLRALGLDPGAAVQAPWPLLRTFAAGPALSRDAALLARDTVPTL
GQVAIVTTTAKAGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eccB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECCB2_MYCTU (O05449)

Other databases:

- EMBL:   BX842584
- EMBL:   AE000516
- PIR:   H70598
- RefSeq:   NP_218412.1
- RefSeq:   NP_338563.1
- EnsemblBacteria:   EBMYCT00000000718
- EnsemblBacteria:   EBMYCT00000069471
- GeneID:   886231
- GeneID:   922525
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT4011
- KEGG:   mtu:Rv3895c
- TIGR:   MT4011
- TubercuList:   Rv3895c
- GeneTree:   EBGT00050000016351
- HOGENOM:   HBG571250
- OMA:   ISAWAVC
- ProtClustDB:   CLSK792794
- InterPro:   IPR007795

Pfam domain/function: PF05108 DUF690

EC number: NA

Molecular weight: Translated: 51587; Mature: 51456

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x227f63ec)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSLSNRDQNSGHLFYNRRLRAATTRFSVRMKHDDRKQTAALALSMVLVAIAAGWMMLL
CCCCCCCCCCCCCEEEEECEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
NVLKPTGIVGDSAIIGDRDSGALYARIDGRLYPALNLTSARLATGTAGQPTWVKPAEIAK
HHHCCCCCCCCCEEECCCCCCEEEEEECCEEECCCCCCCHHEECCCCCCCCCCCHHHHHC
YPTGPLVGIPGAPAAMPVNRGAVSAWAVCDTAGRPRSADKPVVTSIAGPITGGGRATHLR
CCCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEE
DDAGLLVTFDGSTYVIWGGKRSQIDPTNRAVTLSLGLDPGVTSPIQISRALFDGLPATEP
CCCCEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCC
LRVPAVPEAGTPSTWVPGARVGSVLQAQTAGGGSQFYVLLPDGVQKISSFVADLLRSANS
EECCCCCCCCCCCCCCCCHHHHHHHEEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCCC
YGAAAPRVVTPDVLVHTPQVTSLPVEYYPAGRLNFVDTAADPTTCVSWEKASTDPQARVA
CCCCCCCEECCHHEEECCCCCCCCEEECCCCCCEEEECCCCCCEEEECCCCCCCCCEEEE
VYNGRGLPVPPSMDSRIVRLVRDDRAPASVVATQVLVLPGAANFVTSTSGVITAESRESL
EECCCCCCCCCCHHHHHHHHHHCCCCCHHHHEEEEEEECCCCHHEECCCCEEEECCCCCE
FWVSGNGVRFGIANDEATLRALGLDPGAAVQAPWPLLRTFAAGPALSRDAALLARDTVPT
EEEECCCEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCC
LGQVAIVTTTAKAGA
CCCEEEEEECCCCCH
>Mature Secondary Structure 
PLSLSNRDQNSGHLFYNRRLRAATTRFSVRMKHDDRKQTAALALSMVLVAIAAGWMMLL
CCCCCCCCCCCCEEEEECEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
NVLKPTGIVGDSAIIGDRDSGALYARIDGRLYPALNLTSARLATGTAGQPTWVKPAEIAK
HHHCCCCCCCCCEEECCCCCCEEEEEECCEEECCCCCCCHHEECCCCCCCCCCCHHHHHC
YPTGPLVGIPGAPAAMPVNRGAVSAWAVCDTAGRPRSADKPVVTSIAGPITGGGRATHLR
CCCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEE
DDAGLLVTFDGSTYVIWGGKRSQIDPTNRAVTLSLGLDPGVTSPIQISRALFDGLPATEP
CCCCEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCC
LRVPAVPEAGTPSTWVPGARVGSVLQAQTAGGGSQFYVLLPDGVQKISSFVADLLRSANS
EECCCCCCCCCCCCCCCCHHHHHHHEEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCCC
YGAAAPRVVTPDVLVHTPQVTSLPVEYYPAGRLNFVDTAADPTTCVSWEKASTDPQARVA
CCCCCCCEECCHHEEECCCCCCCCEEECCCCCCEEEECCCCCCEEEECCCCCCCCCEEEE
VYNGRGLPVPPSMDSRIVRLVRDDRAPASVVATQVLVLPGAANFVTSTSGVITAESRESL
EECCCCCCCCCCHHHHHHHHHHCCCCCHHHHEEEEEEECCCCHHEECCCCEEEECCCCCE
FWVSGNGVRFGIANDEATLRALGLDPGAAVQAPWPLLRTFAAGPALSRDAALLARDTVPT
EEEECCCEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCC
LGQVAIVTTTAKAGA
CCCEEEEEECCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036