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The map label for this gene is polX [H]

Identifier: 148663724

GI number: 148663724

Start: 4336847

End: 4337854

Strand: Reverse

Name: polX [H]

Synonym: MRA_3896

Alternate gene names: 148663724

Gene position: 4337854-4336847 (Counterclockwise)

Preceding gene: 148663725

Following gene: 148663722

Centisome position: 98.14

GC content: 67.06

Gene sequence:

>1008_bases
ATGGACCCGGTAACAGCGCTGCGGCAGATCGCCTATTACAAGGACCGGAACCGCCACGACCCGAGGCGGGTGATGGCCTA
TCGCAATGCCGCCGACATTATCGAGGGCCTTGACGACGCGGCGCGGCAGCGGCACGGCCAGGCCAACAGCTGGCAGTCGC
TGGCGGGTATCGGTCCCAAAACCGCGAAAGTCATCGCCCAGGCCTGGTCTGGCCGCGAGCCGGACCTGCTGGCTGAATTA
CGCGCTGACGCTGAGGATCTCGGTGGAGGGGCGATCCGTGCCGCATTGCGCGGGGATCTGCATCTGCATTCGAACTGGTC
GGACGGGTCCGCGCCGATCGAGGAGATGATGGCCACCGCGGCGGCGCTAGGTCACCAGTACTGCGCATTGACCGATCACT
CACCGCGGTTGACGATCGCCAACGGCCTGTCTCCGGACCGGTTGCGCAAGCAGCTGGACGTGATCGACGAGCTGCGCGAG
AAGTTCGCGCCGCTGCGCATCCTGACCGGGATCGAGGTCGACATCCTCGAAGACGGGAGCTTGGACCAGGAACCCGAGAT
GCTGGACCGCCTCGACATCGTGGTGGCCAGCGTGCACTCCAAGCTGTCGATGGATTCGGCAGCGATGACGCGACGGATGG
TGCGCGCCGTGGCCAACGGTCACACCGACGTGCTGGGCCACTGCACCGGCCGGCTGATCGCCGGCAATCGTGGCATCCGG
CCAGAATCGAAGTTCGATGCAGAGGCGGTGTTCACCGCCTGCCGTGAGCACGGCACCGCCGTGGAGATCAACTCCCGTCC
GGAACGCCGAGACCCACCGACGCGCCTGTTGCACCTAGCGCGCGACATCGGCTGCGTGTTCAGCATCGACACCGACGCGC
ACGCACCCGGCCAGCTGGACTTCCTCGGCTACGGCGCCCAGCGCGCCTTGGACGCGGAGGTGCCCGCCGACCGGATCGTC
AACACCTGGCCGGCCGACACGCTCCTGGCGTGGACCGGGTCGCATTAG

Upstream 100 bases:

>100_bases
GTGCGGGGGTGTTAATGGCGTTGCTCATCCTCGGCGAAATGGCCGGCTTCGCGGTGGTTGTCACCGGGGTCGTCTTCGGG
CAACTGGTGTGAGCCCGATA

Downstream 100 bases:

>100_bases
CCCGCTGTCGGCCACGAACACCGCGGTACCAGGCGGCAACGCCACGTGTCCGACATGCGAATGCACCCGCTCCTATATGA
CCGCACGCCATTGCCTACCC

Product: hypothetical protein

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MDPVTALRQIAYYKDRNRHDPRRVMAYRNAADIIEGLDDAARQRHGQANSWQSLAGIGPKTAKVIAQAWSGREPDLLAEL
RADAEDLGGGAIRAALRGDLHLHSNWSDGSAPIEEMMATAAALGHQYCALTDHSPRLTIANGLSPDRLRKQLDVIDELRE
KFAPLRILTGIEVDILEDGSLDQEPEMLDRLDIVVASVHSKLSMDSAAMTRRMVRAVANGHTDVLGHCTGRLIAGNRGIR
PESKFDAEAVFTACREHGTAVEINSRPERRDPPTRLLHLARDIGCVFSIDTDAHAPGQLDFLGYGAQRALDAEVPADRIV
NTWPADTLLAWTGSH

Sequences:

>Translated_335_residues
MDPVTALRQIAYYKDRNRHDPRRVMAYRNAADIIEGLDDAARQRHGQANSWQSLAGIGPKTAKVIAQAWSGREPDLLAEL
RADAEDLGGGAIRAALRGDLHLHSNWSDGSAPIEEMMATAAALGHQYCALTDHSPRLTIANGLSPDRLRKQLDVIDELRE
KFAPLRILTGIEVDILEDGSLDQEPEMLDRLDIVVASVHSKLSMDSAAMTRRMVRAVANGHTDVLGHCTGRLIAGNRGIR
PESKFDAEAVFTACREHGTAVEINSRPERRDPPTRLLHLARDIGCVFSIDTDAHAPGQLDFLGYGAQRALDAEVPADRIV
NTWPADTLLAWTGSH
>Mature_335_residues
MDPVTALRQIAYYKDRNRHDPRRVMAYRNAADIIEGLDDAARQRHGQANSWQSLAGIGPKTAKVIAQAWSGREPDLLAEL
RADAEDLGGGAIRAALRGDLHLHSNWSDGSAPIEEMMATAAALGHQYCALTDHSPRLTIANGLSPDRLRKQLDVIDELRE
KFAPLRILTGIEVDILEDGSLDQEPEMLDRLDIVVASVHSKLSMDSAAMTRRMVRAVANGHTDVLGHCTGRLIAGNRGIR
PESKFDAEAVFTACREHGTAVEINSRPERRDPPTRLLHLARDIGCVFSIDTDAHAPGQLDFLGYGAQRALDAEVPADRIV
NTWPADTLLAWTGSH

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 36702; Mature: 36702

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPVTALRQIAYYKDRNRHDPRRVMAYRNAADIIEGLDDAARQRHGQANSWQSLAGIGPK
CCHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHH
TAKVIAQAWSGREPDLLAELRADAEDLGGGAIRAALRGDLHLHSNWSDGSAPIEEMMATA
HHHHHHHHHCCCCCHHHHHHHCCHHHHCCHHHHHHHHCCEEEECCCCCCCCCHHHHHHHH
AALGHQYCALTDHSPRLTIANGLSPDRLRKQLDVIDELREKFAPLRILTGIEVDILEDGS
HHHCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCC
LDQEPEMLDRLDIVVASVHSKLSMDSAAMTRRMVRAVANGHTDVLGHCTGRLIAGNRGIR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEECCCCCC
PESKFDAEAVFTACREHGTAVEINSRPERRDPPTRLLHLARDIGCVFSIDTDAHAPGQLD
CCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCEE
FLGYGAQRALDAEVPADRIVNTWPADTLLAWTGSH
EECCCHHHHCCCCCCHHHHHCCCCCCCEEEECCCC
>Mature Secondary Structure
MDPVTALRQIAYYKDRNRHDPRRVMAYRNAADIIEGLDDAARQRHGQANSWQSLAGIGPK
CCHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHH
TAKVIAQAWSGREPDLLAELRADAEDLGGGAIRAALRGDLHLHSNWSDGSAPIEEMMATA
HHHHHHHHHCCCCCHHHHHHHCCHHHHCCHHHHHHHHCCEEEECCCCCCCCCHHHHHHHH
AALGHQYCALTDHSPRLTIANGLSPDRLRKQLDVIDELREKFAPLRILTGIEVDILEDGS
HHHCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCC
LDQEPEMLDRLDIVVASVHSKLSMDSAAMTRRMVRAVANGHTDVLGHCTGRLIAGNRGIR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEECCCCCC
PESKFDAEAVFTACREHGTAVEINSRPERRDPPTRLLHLARDIGCVFSIDTDAHAPGQLD
CCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCEE
FLGYGAQRALDAEVPADRIVNTWPADTLLAWTGSH
EECCCHHHHCCCCCCHHHHHCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]