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The map label for this gene is papA1

Identifier: 148663692

GI number: 148663692

Start: 4300085

End: 4301620

Strand: Reverse

Name: papA1

Synonym: MRA_3864

Alternate gene names: 148663692

Gene position: 4301620-4300085 (Counterclockwise)

Preceding gene: 148663693

Following gene: 148663691

Centisome position: 97.32

GC content: 57.49

Gene sequence:

>1536_bases
GTGCGAATAGGACCAGTAGAGTTGTCAGCGGTCAAAGACTGGGACCCAGCGCCCGGCGTGTTAGTTTCGTGGCACCCAAC
ACCTGCCTCGTGCGCGAAAGCCCTTGCAGCGCCGGTGAGTGCTGTGCCTCCCAGTTATGTACAAGCCAGACAAATTCGGA
GCTTTTCTGAGCAGGCTGCCCGGGGGCTCGATCACTCGCGGCTGCTCATTGCGTCCGTTGAGGTGTTTGGTCACTGCGAT
CTGCGCGCCATGACCTATGTCATCAATGCGCACCTTCGTCGGCACGATACATACCGCAGCTGGTTCGAGCTTCGAGATAC
CGACCACATCGTTCGGCACAGCATCGCCGATCCGGCGGATATCGAATTTGTTCCGACCACACATGGCGAGATGACGAGCG
CGGACCTGCGACAGCACATCGTGGCGACACCGGATTCGCTTCATTGGGACTGCTTCAGCTTCGGAGTCATTCAGCGAGCA
GACTCCTTCACGTTCTATGCCAGCATCGATCATCTGCATGCGGACGGTCAGTTCGTAGGAGTCGGACTCATGGAGTTCCA
GTCGATGTACACCGCGCTGATAATGGGTGAGCCACCGATTGGGTTATCGGAGGCTGGCAGCTATGTGGACTTCTGCGTCA
GGCAGCACGAGTACACCTCGGCGTTGACCGTCGATTCCCCGGAGGTGCGCGCGTGGATCGACTTCGCCGAAATCAATAAC
GGAACTTTCCCGGAATTTCCGCTGCCCCTCGGAGATCCGTCTGTACGCTGCGGCGGCGACCTGCTCAGCATGATGCTAAT
GGACGAGCAGCAAACACAGCGATTCGAATCCGCCTGCATGGCGGCGAACGCTCGTTTCATTGGTGGCATGCTGGCTTGCA
TCGCCATCGCGATACACGAGTTGACCGGCGCCGATACCTATTTTGGAATTACTCCCAAAGATATCCGCACACCAGCCGAC
CTTATGACGCAGGGGTGGTTCACCGGGCAGATCCCGGTGACCGTTCCAGTCGCCGGATTGTCCTTTAACGAGATTGCACG
AATCGCGCAGACCTCCTTCGATACTGGTGCGGATCTGGCGAAAGTGCCGTTCGAACGGGTCGTCGAATTGTCGCCGTCGC
TGCGCAGGCCCCAACCGCTTTTTTCCCTGGTGAACTTTTTCGACGCACAAGTGGGACCGCTCTCGGCGGTGACGAAACTG
TTCGAGGGCCTCAACGTTGGTACCTACAGCGACGGGAGGGTCACCTATCCGCTAAGTACGATGGTCGGTCGTTTCGACGA
GACCGCGGCGAGCGTGCTATTCCCAGATAATCCGGTCGCTCGCGAATCCGTTACCGCATATCTGAGGGCAATTAGATCGG
TGTGTATGCGCATTGCCAACGGTGGGACGGCGGAACGTGTAGGCAACGTCGTTGCGCTTTCCCCAGGCCGGCGAAATAAC
ATCGAAAGGATGACATGGCGGTCTTGTCGCGCGGGTGATTTTATCGATATCTGCAATCTAAAGGTTGCGAATGTGACGGT
AGATAGAGAAGCTTAG

Upstream 100 bases:

>100_bases
AACAGCTGGCGCCCGACGACGCTCCTGCTGCCGCGCTGTCGTCACAGTAAGAACGTTTCGCCGCATACGTATTCCGCACG
CGCTGAAATAGGAGCTATTA

Downstream 100 bases:

>100_bases
TGGTTGCGCACGTAAATTCGTCAGGTGACCGATCCCCTGCTGTCTCACTCGCCTCACAGCGACCACCACGGCTGGCGCTC
AAGGCGGGCACGTGCGGAGC

Product: putative polyketide synthase associated protein PapA1

Products: NA

Alternate protein names: Polyketide synthase-associated protein A1

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MRIGPVELSAVKDWDPAPGVLVSWHPTPASCAKALAAPVSAVPPSYVQARQIRSFSEQAARGLDHSRLLIASVEVFGHCD
LRAMTYVINAHLRRHDTYRSWFELRDTDHIVRHSIADPADIEFVPTTHGEMTSADLRQHIVATPDSLHWDCFSFGVIQRA
DSFTFYASIDHLHADGQFVGVGLMEFQSMYTALIMGEPPIGLSEAGSYVDFCVRQHEYTSALTVDSPEVRAWIDFAEINN
GTFPEFPLPLGDPSVRCGGDLLSMMLMDEQQTQRFESACMAANARFIGGMLACIAIAIHELTGADTYFGITPKDIRTPAD
LMTQGWFTGQIPVTVPVAGLSFNEIARIAQTSFDTGADLAKVPFERVVELSPSLRRPQPLFSLVNFFDAQVGPLSAVTKL
FEGLNVGTYSDGRVTYPLSTMVGRFDETAASVLFPDNPVARESVTAYLRAIRSVCMRIANGGTAERVGNVVALSPGRRNN
IERMTWRSCRAGDFIDICNLKVANVTVDREA

Sequences:

>Translated_511_residues
MRIGPVELSAVKDWDPAPGVLVSWHPTPASCAKALAAPVSAVPPSYVQARQIRSFSEQAARGLDHSRLLIASVEVFGHCD
LRAMTYVINAHLRRHDTYRSWFELRDTDHIVRHSIADPADIEFVPTTHGEMTSADLRQHIVATPDSLHWDCFSFGVIQRA
DSFTFYASIDHLHADGQFVGVGLMEFQSMYTALIMGEPPIGLSEAGSYVDFCVRQHEYTSALTVDSPEVRAWIDFAEINN
GTFPEFPLPLGDPSVRCGGDLLSMMLMDEQQTQRFESACMAANARFIGGMLACIAIAIHELTGADTYFGITPKDIRTPAD
LMTQGWFTGQIPVTVPVAGLSFNEIARIAQTSFDTGADLAKVPFERVVELSPSLRRPQPLFSLVNFFDAQVGPLSAVTKL
FEGLNVGTYSDGRVTYPLSTMVGRFDETAASVLFPDNPVARESVTAYLRAIRSVCMRIANGGTAERVGNVVALSPGRRNN
IERMTWRSCRAGDFIDICNLKVANVTVDREA
>Mature_511_residues
MRIGPVELSAVKDWDPAPGVLVSWHPTPASCAKALAAPVSAVPPSYVQARQIRSFSEQAARGLDHSRLLIASVEVFGHCD
LRAMTYVINAHLRRHDTYRSWFELRDTDHIVRHSIADPADIEFVPTTHGEMTSADLRQHIVATPDSLHWDCFSFGVIQRA
DSFTFYASIDHLHADGQFVGVGLMEFQSMYTALIMGEPPIGLSEAGSYVDFCVRQHEYTSALTVDSPEVRAWIDFAEINN
GTFPEFPLPLGDPSVRCGGDLLSMMLMDEQQTQRFESACMAANARFIGGMLACIAIAIHELTGADTYFGITPKDIRTPAD
LMTQGWFTGQIPVTVPVAGLSFNEIARIAQTSFDTGADLAKVPFERVVELSPSLRRPQPLFSLVNFFDAQVGPLSAVTKL
FEGLNVGTYSDGRVTYPLSTMVGRFDETAASVLFPDNPVARESVTAYLRAIRSVCMRIANGGTAERVGNVVALSPGRRNN
IERMTWRSCRAGDFIDICNLKVANVTVDREA

Specific function: Catalyzes an acylation step during the biosynthesis of a cell wall sulfolipid

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the papA acyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAPA1_MYCBO (Q7TVK9)

Other databases:

- EMBL:   BX248347
- RefSeq:   NP_857491.1
- ProteinModelPortal:   Q7TVK9
- EnsemblBacteria:   EBMYCT00000014398
- GeneID:   1093825
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3854c
- GeneTree:   EBGT00050000015302
- HOGENOM:   HBG657620
- OMA:   AEIHLMY
- ProtClustDB:   CLSK790999
- BioCyc:   MBOV233413:MB3854C-MONOMER
- InterPro:   IPR001242

Pfam domain/function: PF00668 Condensation

EC number: NA

Molecular weight: Translated: 56128; Mature: 56128

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGPVELSAVKDWDPAPGVLVSWHPTPASCAKALAAPVSAVPPSYVQARQIRSFSEQAA
CCCCCEEEEEECCCCCCCCEEEEECCCHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHH
RGLDHSRLLIASVEVFGHCDLRAMTYVINAHLRRHDTYRSWFELRDTDHIVRHSIADPAD
CCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
IEFVPTTHGEMTSADLRQHIVATPDSLHWDCFSFGVIQRADSFTFYASIDHLHADGQFVG
EEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEEECEEECCCCEEE
VGLMEFQSMYTALIMGEPPIGLSEAGSYVDFCVRQHEYTSALTVDSPEVRAWIDFAEINN
HHHHHHHHHHHEEEECCCCCCHHHCCHHHHHHHHHHHCCCEEECCCCCCEEEEEHHHCCC
GTFPEFPLPLGDPSVRCGGDLLSMMLMDEQQTQRFESACMAANARFIGGMLACIAIAIHE
CCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
LTGADTYFGITPKDIRTPADLMTQGWFTGQIPVTVPVAGLSFNEIARIAQTSFDTGADLA
HCCCCEEECCCHHHHCCCHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCHH
KVPFERVVELSPSLRRPQPLFSLVNFFDAQVGPLSAVTKLFEGLNVGTYSDGRVTYPLST
HCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEHHH
MVGRFDETAASVLFPDNPVARESVTAYLRAIRSVCMRIANGGTAERVGNVVALSPGRRNN
HHCCHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCEEEECCCCCCC
IERMTWRSCRAGDFIDICNLKVANVTVDREA
CHHHHHHCCCCCCCEEECCEEEEEEEECCCC
>Mature Secondary Structure
MRIGPVELSAVKDWDPAPGVLVSWHPTPASCAKALAAPVSAVPPSYVQARQIRSFSEQAA
CCCCCEEEEEECCCCCCCCEEEEECCCHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHH
RGLDHSRLLIASVEVFGHCDLRAMTYVINAHLRRHDTYRSWFELRDTDHIVRHSIADPAD
CCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
IEFVPTTHGEMTSADLRQHIVATPDSLHWDCFSFGVIQRADSFTFYASIDHLHADGQFVG
EEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEEECEEECCCCEEE
VGLMEFQSMYTALIMGEPPIGLSEAGSYVDFCVRQHEYTSALTVDSPEVRAWIDFAEINN
HHHHHHHHHHHEEEECCCCCCHHHCCHHHHHHHHHHHCCCEEECCCCCCEEEEEHHHCCC
GTFPEFPLPLGDPSVRCGGDLLSMMLMDEQQTQRFESACMAANARFIGGMLACIAIAIHE
CCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
LTGADTYFGITPKDIRTPADLMTQGWFTGQIPVTVPVAGLSFNEIARIAQTSFDTGADLA
HCCCCEEECCCHHHHCCCHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCHH
KVPFERVVELSPSLRRPQPLFSLVNFFDAQVGPLSAVTKLFEGLNVGTYSDGRVTYPLST
HCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEHHH
MVGRFDETAASVLFPDNPVARESVTAYLRAIRSVCMRIANGGTAERVGNVVALSPGRRNN
HHCCHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCEEEECCCCCCC
IERMTWRSCRAGDFIDICNLKVANVTVDREA
CHHHHHHCCCCCCCEEECCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972