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The map label for this gene is csd [H]

Identifier: 148663646

GI number: 148663646

Start: 4232145

End: 4233341

Strand: Reverse

Name: csd [H]

Synonym: MRA_3818

Alternate gene names: 148663646

Gene position: 4233341-4232145 (Counterclockwise)

Preceding gene: 148663654

Following gene: 148663641

Centisome position: 95.78

GC content: 66.42

Gene sequence:

>1197_bases
ATGGCATACGACGTCGCCCGGGTGCGCGGATTGCACCCATCGCTGGGTGACGGATGGGTGCACTTCGATGCACCGGCCGG
AATGCTGATTCCCGATTCCGTCGCGACCACCGTGTCGACGGCCTTCCGCCGGTCGGGCGCTAGCACAGTGGGTGCTCACC
CGTCGGCGCGGCGTAGCGCGGCGGTACTCGACGCCGCCCGTGAAGCGGTGGCCGATCTGGTCAACGCTGACCCGGGCGGC
GTGGTGCTGGGCGCCGACCGGGCGGTGCTGCTGTCGTTGCTGGCCGAAGCGTCGTCCTCACGCGCCGGGCTGGGATACGA
AGTGATCGTCAGTCGTCTTGACGACGAGGCCAACATCGCTCCGTGGCTGCGGGCGGCGCACCGCTACGGCGCCAAGGTTA
AGTGGGCCGAGGTCGACATCGAGACCGGCGAGCTGCCGACGTGGCAGTGGGAGAGCCTGATCAGCAAGTCAACCAGGCTG
GTCGCCGTCAACTCCGCATCCGGAACGCTGGGCGGGGTCACCGATCTGCGGGCGATGACCAAACTGGTGCACGACGTGGG
GGCACTGGTGGTGGTCGACCATTCCGCGGCCGCGCCGTATCGGTTGCTCGATATCAGAGAAACCGACGCCGACGTGGTGA
CGGTGAATGCGCATGCCTGGGGTGGTCCGCCGATTGGGGCGATGGTTTTCCGTGACCCGTCAGTGATGAATTCCTTCGGA
TCGGTTTCGACCAATCCGTATGCCACCGGGCCGGCGCGCCTGGAGATCGGCGTGCACCAGTTTGGTCTGCTGGCTGGTGT
GGTCGCCAGCATTGAGTACCTGGCGGCGCTCGACGAGTCGGCTCGCGGCAGCAGACGCGAACGACTAGCGGTGTCGATGC
AATCTGCTGACGCGTACCTGAACCGGGTCTTCGACTATCTGATGGTGTCGTTGCGCTCGCTGCCATTGGTGATGCTGATC
GGTCGCCCGGAAGCACAGATACCGGTGGTCAGCTTCGCGGTCCACAAGGTGCCGGCTGACCGCGTGGTGCAGCGGCTGGC
GGACAACGGAATTCTCGCGATCGCCAACACCGGCTCACGCGTGCTCGACGTGCTGGGCGTCAACGACGTCGGCGGCGCGG
TCACCGTCGGGCTGGCGCATTACTCGACGATGGCCGAAGTCGACCAGCTGGTGCGCGCGCTGGCGTCGCTAGGTTGA

Upstream 100 bases:

>100_bases
CACAGGCCCACTCGATTAGTATGGCTGGCCGGGTGACATGGCTCAGGGAAGCCCGGGCGGGCTGGGACGTCTAGGACACC
CGAGTTCTAAGGTGGCTGGC

Downstream 100 bases:

>100_bases
TCCGGCCGCGAGGTTCGCCTATACCGTCAGCAGAATCTTTCCGAACGTCTTGCCCGACAACATCAGTTCATGCGCTTGTG
CCGCCTGTTGGATGGGCAGC

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGASTVGAHPSARRSAAVLDAAREAVADLVNADPGG
VVLGADRAVLLSLLAEASSSRAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQWESLISKSTRL
VAVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAPYRLLDIRETDADVVTVNAHAWGGPPIGAMVFRDPSVMNSFG
SVSTNPYATGPARLEIGVHQFGLLAGVVASIEYLAALDESARGSRRERLAVSMQSADAYLNRVFDYLMVSLRSLPLVMLI
GRPEAQIPVVSFAVHKVPADRVVQRLADNGILAIANTGSRVLDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG

Sequences:

>Translated_398_residues
MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGASTVGAHPSARRSAAVLDAAREAVADLVNADPGG
VVLGADRAVLLSLLAEASSSRAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQWESLISKSTRL
VAVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAPYRLLDIRETDADVVTVNAHAWGGPPIGAMVFRDPSVMNSFG
SVSTNPYATGPARLEIGVHQFGLLAGVVASIEYLAALDESARGSRRERLAVSMQSADAYLNRVFDYLMVSLRSLPLVMLI
GRPEAQIPVVSFAVHKVPADRVVQRLADNGILAIANTGSRVLDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG
>Mature_397_residues
AYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGASTVGAHPSARRSAAVLDAAREAVADLVNADPGGV
VLGADRAVLLSLLAEASSSRAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQWESLISKSTRLV
AVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAPYRLLDIRETDADVVTVNAHAWGGPPIGAMVFRDPSVMNSFGS
VSTNPYATGPARLEIGVHQFGLLAGVVASIEYLAALDESARGSRRERLAVSMQSADAYLNRVFDYLMVSLRSLPLVMLIG
RPEAQIPVVSFAVHKVPADRVVQRLADNGILAIANTGSRVLDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=421, Percent_Identity=24.7030878859857, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789175, Length=411, Percent_Identity=26.7639902676399, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI48994898, Length=359, Percent_Identity=22.8412256267409, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319831, Length=358, Percent_Identity=22.9050279329609, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41852; Mature: 41721

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGASTVGAHPSARRSA
CCCCCHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AVLDAAREAVADLVNADPGGVVLGADRAVLLSLLAEASSSRAGLGYEVIVSRLDDEANIA
HHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHH
PWLRAAHRYGAKVKWAEVDIETGELPTWQWESLISKSTRLVAVNSASGTLGGVTDLRAMT
HHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHH
KLVHDVGALVVVDHSAAAPYRLLDIRETDADVVTVNAHAWGGPPIGAMVFRDPSVMNSFG
HHHHHCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEEECCHHHHHHCC
SVSTNPYATGPARLEIGVHQFGLLAGVVASIEYLAALDESARGSRRERLAVSMQSADAYL
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHH
NRVFDYLMVSLRSLPLVMLIGRPEAQIPVVSFAVHKVPADRVVQRLADNGILAIANTGSR
HHHHHHHHHHHHCCCEEEEECCCCCCCCCEEHHHHCCCHHHHHHHHHCCCEEEEECCCCC
VLDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG
EEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGASTVGAHPSARRSA
CCCCHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AVLDAAREAVADLVNADPGGVVLGADRAVLLSLLAEASSSRAGLGYEVIVSRLDDEANIA
HHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHH
PWLRAAHRYGAKVKWAEVDIETGELPTWQWESLISKSTRLVAVNSASGTLGGVTDLRAMT
HHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHH
KLVHDVGALVVVDHSAAAPYRLLDIRETDADVVTVNAHAWGGPPIGAMVFRDPSVMNSFG
HHHHHCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEEECCHHHHHHCC
SVSTNPYATGPARLEIGVHQFGLLAGVVASIEYLAALDESARGSRRERLAVSMQSADAYL
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHH
NRVFDYLMVSLRSLPLVMLIGRPEAQIPVVSFAVHKVPADRVVQRLADNGILAIANTGSR
HHHHHHHHHHHHCCCEEEEECCCCCCCCCEEHHHHCCCHHHHHHHHHCCCEEEEECCCCC
VLDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG
EEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]