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The map label for this gene is proW [H]

Identifier: 148663623

GI number: 148663623

Start: 4211056

End: 4211745

Strand: Reverse

Name: proW [H]

Synonym: MRA_3795

Alternate gene names: 148663623

Gene position: 4211745-4211056 (Counterclockwise)

Preceding gene: 148663624

Following gene: 148663622

Centisome position: 95.29

GC content: 66.96

Gene sequence:

>690_bases
ATGCACTACCTGATGACCCACCCGGGAGCGGCCTGGGCGCTGACCGTCGTCCATCTGCGCCTCTCGTTGCTGCCGGTGCT
GATCGGGCTGATGAGCGCGGTGCCGTTGGGCCTGCTGGTGCAGCGCGCGCCGCTGCTTCGCCGGCTGACGACGGCGACCG
CCAGCGTTATATTCACCATCCCGTCGCTAGCGCTATTCGTGGTGTTGCCGCTGATCATCGGAACCCGGATCCTCGACGAG
GCCAATGTCATTGTGGCGTTGGCGGCCTACACCACGGCCCTGCTGGTGCGGGCGGTGCTCGAAGCGCTGGACGCGGTGCC
GGCGCAGGTGCATGACGCGGCCACCGCCATCGGCTATTCGCGGATCGCTCAGATGTTGAAAGTCGAACTGCCGCTGTCTA
TCCCCGTGCTGGTAGCCGGGCTGCGGGTGGTCGCGGTTACCAACATCGCGATGGTGTCCGTGGGTTCGGTGATAGGAATC
GGGGGCCTGGGAACCTGGTTCACCGCGGGGTATCAGACCAACAAGAGTGACCAGATCGTTGCCGGCGTCGTAGCGATGTT
CCTGCTGGCGATTGTCGTCGACGTGGTGATCAACCTCGCCGGTCGGCTGGCCACGCCATGGGAACGGGCGCCGCGGGCAG
CCCGTCGGCGCCGCCAGGTCGCGGCCCCGATCACGGGCGGAGCGCGATGA

Upstream 100 bases:

>100_bases
TCGCCGTTGACGGCGGTGGCAAGGTCATCGGCGGGATACTGGCCGCCGACGTGCTGGCCGAGTTCCAAAAAGGCAAGAAG
GCCGGCGGCGGAGCTAAGCC

Downstream 100 bases:

>100_bases
ATTTCCTGCAGCAGGCGCTGTCCTACCTGCTAACCGCCAGTAACTGGACCGGTCCAGTCGGCTTGGCAGTCCGCACGTGT
GAGCACCTGGAATACACCGC

Product: amino acid ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MHYLMTHPGAAWALTVVHLRLSLLPVLIGLMSAVPLGLLVQRAPLLRRLTTATASVIFTIPSLALFVVLPLIIGTRILDE
ANVIVALAAYTTALLVRAVLEALDAVPAQVHDAATAIGYSRIAQMLKVELPLSIPVLVAGLRVVAVTNIAMVSVGSVIGI
GGLGTWFTAGYQTNKSDQIVAGVVAMFLLAIVVDVVINLAGRLATPWERAPRAARRRRQVAAPITGGAR

Sequences:

>Translated_229_residues
MHYLMTHPGAAWALTVVHLRLSLLPVLIGLMSAVPLGLLVQRAPLLRRLTTATASVIFTIPSLALFVVLPLIIGTRILDE
ANVIVALAAYTTALLVRAVLEALDAVPAQVHDAATAIGYSRIAQMLKVELPLSIPVLVAGLRVVAVTNIAMVSVGSVIGI
GGLGTWFTAGYQTNKSDQIVAGVVAMFLLAIVVDVVINLAGRLATPWERAPRAARRRRQVAAPITGGAR
>Mature_229_residues
MHYLMTHPGAAWALTVVHLRLSLLPVLIGLMSAVPLGLLVQRAPLLRRLTTATASVIFTIPSLALFVVLPLIIGTRILDE
ANVIVALAAYTTALLVRAVLEALDAVPAQVHDAATAIGYSRIAQMLKVELPLSIPVLVAGLRVVAVTNIAMVSVGSVIGI
GGLGTWFTAGYQTNKSDQIVAGVVAMFLLAIVVDVVINLAGRLATPWERAPRAARRRRQVAAPITGGAR

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=195, Percent_Identity=31.7948717948718, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788449, Length=188, Percent_Identity=31.3829787234043, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24109; Mature: 24109

Theoretical pI: Translated: 11.73; Mature: 11.73

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYLMTHPGAAWALTVVHLRLSLLPVLIGLMSAVPLGLLVQRAPLLRRLTTATASVIFTI
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PSLALFVVLPLIIGTRILDEANVIVALAAYTTALLVRAVLEALDAVPAQVHDAATAIGYS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
RIAQMLKVELPLSIPVLVAGLRVVAVTNIAMVSVGSVIGIGGLGTWFTAGYQTNKSDQIV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHH
AGVVAMFLLAIVVDVVINLAGRLATPWERAPRAARRRRQVAAPITGGAR
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHYLMTHPGAAWALTVVHLRLSLLPVLIGLMSAVPLGLLVQRAPLLRRLTTATASVIFTI
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PSLALFVVLPLIIGTRILDEANVIVALAAYTTALLVRAVLEALDAVPAQVHDAATAIGYS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
RIAQMLKVELPLSIPVLVAGLRVVAVTNIAMVSVGSVIGIGGLGTWFTAGYQTNKSDQIV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHH
AGVVAMFLLAIVVDVVINLAGRLATPWERAPRAARRRRQVAAPITGGAR
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7592481; 10216873; 9384377 [H]