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The map label for this gene is proZ [H]

Identifier: 148663622

GI number: 148663622

Start: 4210340

End: 4211059

Strand: Reverse

Name: proZ [H]

Synonym: MRA_3794

Alternate gene names: 148663622

Gene position: 4211059-4210340 (Counterclockwise)

Preceding gene: 148663623

Following gene: 148663621

Centisome position: 95.27

GC content: 65.97

Gene sequence:

>720_bases
ATGAATTTCCTGCAGCAGGCGCTGTCCTACCTGCTAACCGCCAGTAACTGGACCGGTCCAGTCGGCTTGGCAGTCCGCAC
GTGTGAGCACCTGGAATACACCGCGGTGGCGGTGGCCGCTTCAGCACTGATCGCCGTGCCAGTCGGGCTGCTTATCGGGC
ACACCGGTCGCGGGACGCTGCTGGTGGTGGGTGCGGTCAATGGTTTGCGCGCTTTGCCCACGTTGGGTGTTCTGCTGCTA
GGGGTGCTGCTATTCGGGCTGGGATTGGGGCCGCCGCTGGTGGCGCTGATGCTGTTGGGTATCCCGTCTTTGCTGGCCAG
CACGTACGCCGGCATTGCCAGTGTTGATCCGCTGGTGGTCGATGCCGCCCGGGCGATGGGCATGACCGAGTCCCAGGTGC
TGCTGCGCGTCGAGGTACCCAATGCACTACCGCTGATGCTCGGCGGACTACGCAGCGCGACGCTGCAAGTGGTCGCCACC
GCGACGGTGGCCGCCTACGCCAGTCTCGGGGGGCTGGGTGGCTACTTGATCGACGGGATCAAGGAGCGTCGATTCCACAT
CGCTCTGGTCGGTGCGATGATGGTGGCCGCGTTGGCGTTGACCCTCGACGGACTGCTGGCGTTGGCGGGGTGGGTATCGG
TGCCGGGCACCGGGAGGATGCGCAAGCTCGCCGCGGTTGTCGACAAACCTGCCGCAGGCGGTGGACACGCCCTACGGTAG

Upstream 100 bases:

>100_bases
TGATCAACCTCGCCGGTCGGCTGGCCACGCCATGGGAACGGGCGCCGCGGGCAGCCCGTCGGCGCCGCCAGGTCGCGGCC
CCGATCACGGGCGGAGCGCG

Downstream 100 bases:

>100_bases
ACAGTGTGAACGCAGTCCCCTCTGATCTGACTCCGCGCGTCTGGCCGGCCATGTTGACCTGGCGTGCGCAGGACATCTCG
CGCATGGAATCGGTACGAGT

Product: amino acid ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNFLQQALSYLLTASNWTGPVGLAVRTCEHLEYTAVAVAASALIAVPVGLLIGHTGRGTLLVVGAVNGLRALPTLGVLLL
GVLLFGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQVLLRVEVPNALPLMLGGLRSATLQVVAT
ATVAAYASLGGLGGYLIDGIKERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKLAAVVDKPAAGGGHALR

Sequences:

>Translated_239_residues
MNFLQQALSYLLTASNWTGPVGLAVRTCEHLEYTAVAVAASALIAVPVGLLIGHTGRGTLLVVGAVNGLRALPTLGVLLL
GVLLFGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQVLLRVEVPNALPLMLGGLRSATLQVVAT
ATVAAYASLGGLGGYLIDGIKERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKLAAVVDKPAAGGGHALR
>Mature_239_residues
MNFLQQALSYLLTASNWTGPVGLAVRTCEHLEYTAVAVAASALIAVPVGLLIGHTGRGTLLVVGAVNGLRALPTLGVLLL
GVLLFGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQVLLRVEVPNALPLMLGGLRSATLQVVAT
ATVAAYASLGGLGGYLIDGIKERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKLAAVVDKPAAGGGHALR

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=137, Percent_Identity=33.5766423357664, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789033, Length=168, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788451, Length=138, Percent_Identity=34.7826086956522, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24182; Mature: 24182

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFLQQALSYLLTASNWTGPVGLAVRTCEHLEYTAVAVAASALIAVPVGLLIGHTGRGTL
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
LVVGAVNGLRALPTLGVLLLGVLLFGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVV
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCHHHH
DAARAMGMTESQVLLRVEVPNALPLMLGGLRSATLQVVATATVAAYASLGGLGGYLIDGI
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKLAAVVDKPAAGGGHALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNFLQQALSYLLTASNWTGPVGLAVRTCEHLEYTAVAVAASALIAVPVGLLIGHTGRGTL
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
LVVGAVNGLRALPTLGVLLLGVLLFGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVV
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCHHHH
DAARAMGMTESQVLLRVEVPNALPLMLGGLRSATLQVVATATVAAYASLGGLGGYLIDGI
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKLAAVVDKPAAGGGHALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7592481; 10216873; 9384377 [H]