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The map label for this gene is ctpJ [H]

Identifier: 148663609

GI number: 148663609

Start: 4201837

End: 4203819

Strand: Reverse

Name: ctpJ [H]

Synonym: MRA_3781

Alternate gene names: 148663609

Gene position: 4203819-4201837 (Counterclockwise)

Preceding gene: 148663611

Following gene: 148663608

Centisome position: 95.11

GC content: 67.07

Gene sequence:

>1983_bases
GTGGCTGTTCGTGAACTCTCTCCCGCCCGGTGCACCTCAGCGTCGCCGTTGGTCCTAGCGCGCCGAACCAAGCTGTTCGC
GTTGTCGGAGATGCGTTGGGCCGCGCTGGCGTTGGGCCTGTTTTCAGCGGGACTACTGACACAGCTGTGCGGAGCACCGC
AATGGGTGCGGTGGGCGCTGTTTCTGGCGTGCTACGCGACCGGCGGTTGGGAGCCAGGGCTGGCCGGGCTACAGGCGCTA
CAGCGAAGGACCCTAGATGTCGATCTGCTGATGGTGGTCGCGGCGATCGGCGCGGCCGCCATCGGGCAGATCGCCGAGGG
CGCTCTGCTCATTGTCATCTTCGCAACCTCCGGTGCTCTGGAAGCACTGGTAACGGCCCGCACCGCGGACTCGGTGCGTG
GGCTAATGGGCCTCGCGCCGGGCACCGCGACCCGCGTGGGCGCCGGCGGTGGTGAGGAAACGGTCAACGCCGCCGACCTA
AGGATTGGGGACATCGTGCTGGTACGGCCCGGTGAGCGCATCTCGGCGGACGCAACCGTGCTTGCCGGCGGCAGCGAAGT
CGATCAGGCCACCGTCACCGGAGAGCCGCTGCCCGTCGACAAGTCAATCGGCGATCAGGTGTTCGCCGGCACTGTCAACG
GCACCGGCGCCCTGCGGATCCGGGTCGACCGGCTCGCGCGGGATTCCGTCGTCGCTCGCATTGCCACCCTGGTTGAACAG
GCCAGCCAGACCAAGGCGCGCACCCAGCTGTTCATCGAGAAAGTCGAACAACGCTACTCGATCGGCATGGTCGCCGTGAC
CCTCGCCGTATTCGCGGTGCCCCCGCTATGGGGGGAGACCCTGCAGCGGGCGTTGCTGCGAGCCATGACGTTCATGATCG
TCGCGTCGCCGTGTGCGGTCGTGCTGGCCACCATGCCGCCACTATTGGCCGCAATCGCCAACGCCGGCCGCCACGGGGTG
CTCGCCAAGTCCGCGATCGTGATGGAACAACTTGGAACCACCACACGGATCGCGTTCGACAAGACCGGCACCCTTACCCG
CGGTACCCCCGAACTCGCCGGCATCTGGGTGTACGAACGACGATTCACCGATGATGAACTGCTGCGGCTTGCGGCTGCAG
CGGAGTATCCCAGTGAGCACCCACTGGGTGCGGCCATCGTGAAAGCCGCCCAGTCTCGCCGCATCCGGCTGCCGACCGTC
GGCGAGTTCACCGCACACCCAGGTTGCCGTGTCACCGCCCGCGTCGATGGCCACGTCATTGCGGTCGGATCGGCGACGGC
ACTGCTGGGCACTGCCGGCGCCGCCGCGCTCGAAGCTTCCATGATCACGGCGGTCGACTTTCTGCAAGGCGAGGGCTACA
CCGTCGTCGTCGTGGTATGCGATAGCCATCCCGTCGGGCTACTCGCCATCACCGATCAGCTTCGCCCCGAAGCCGCCGCG
GCGATTTCCGCTGCGACCAAACTGACCGGGGCCAAACCGGTATTGCTTACCGGCGACAACCGGGCCACCGCCGATCGGCT
CGGTGTACAGGTTGGCATCGACGACGTACGGGCCGGGCTACTGCCCGACGACAAGGTCGCAGCCGTGCGGCAGCTGCAAG
CTGGAGGTGCCAGATTGACCGTGGTCGGTGACGGTATCAACGACGCTCCGGCCTTAGCGGCCGCGCATGTCGGCATCGCC
ATGGGCAGCGCCCGATCGGAACTCACCCTGCAGACCGCCGACGCCGTCGTCGTCCGCGATGACCTGACCACCATTCCCAC
CGTTATCGCCATGTCGCGGCGAGCCCGCCGCATCGTGGTCGCCAACCTCATCGTGGCCGTGACATTCATCGCCGGGCTCG
TTGTGTGGGACCTGGCCTTCACGTTGCCATTGCCACTGGGCGTCGCCCGACACGAAGGTTCCACCATCATCGTCGGACTC
AATGGGCTGCGCCTACTGCGCCACACGGCCTGGCGCCGCGCCGCTGGCACCGCGCACAGGTGA

Upstream 100 bases:

>100_bases
ACGGACGATTCCTGCCTTCGACCCCGTGCCCCATGGTTAGGCAGCCTATCCCCAAAGAAATAAATGAACATATGATCATA
TATTCTGATATGTTGGCCGG

Downstream 100 bases:

>100_bases
CGCTGTGTCTTGAAAAGTCAAATTGTTGTCTTCTAGTGTCAAGACTCAAGGCCGAGTGCTGGTGCACAGTGAGTTCGGTG
ACGCACACCACCCCCGGTTG

Product: metal cation transporting P-type ATPase CtpJ

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 659

Protein sequence:

>660_residues
MAVRELSPARCTSASPLVLARRTKLFALSEMRWAALALGLFSAGLLTQLCGAPQWVRWALFLACYATGGWEPGLAGLQAL
QRRTLDVDLLMVVAAIGAAAIGQIAEGALLIVIFATSGALEALVTARTADSVRGLMGLAPGTATRVGAGGGEETVNAADL
RIGDIVLVRPGERISADATVLAGGSEVDQATVTGEPLPVDKSIGDQVFAGTVNGTGALRIRVDRLARDSVVARIATLVEQ
ASQTKARTQLFIEKVEQRYSIGMVAVTLAVFAVPPLWGETLQRALLRAMTFMIVASPCAVVLATMPPLLAAIANAGRHGV
LAKSAIVMEQLGTTTRIAFDKTGTLTRGTPELAGIWVYERRFTDDELLRLAAAAEYPSEHPLGAAIVKAAQSRRIRLPTV
GEFTAHPGCRVTARVDGHVIAVGSATALLGTAGAAALEASMITAVDFLQGEGYTVVVVVCDSHPVGLLAITDQLRPEAAA
AISAATKLTGAKPVLLTGDNRATADRLGVQVGIDDVRAGLLPDDKVAAVRQLQAGGARLTVVGDGINDAPALAAAHVGIA
MGSARSELTLQTADAVVVRDDLTTIPTVIAMSRRARRIVVANLIVAVTFIAGLVVWDLAFTLPLPLGVARHEGSTIIVGL
NGLRLLRHTAWRRAAGTAHR

Sequences:

>Translated_660_residues
MAVRELSPARCTSASPLVLARRTKLFALSEMRWAALALGLFSAGLLTQLCGAPQWVRWALFLACYATGGWEPGLAGLQAL
QRRTLDVDLLMVVAAIGAAAIGQIAEGALLIVIFATSGALEALVTARTADSVRGLMGLAPGTATRVGAGGGEETVNAADL
RIGDIVLVRPGERISADATVLAGGSEVDQATVTGEPLPVDKSIGDQVFAGTVNGTGALRIRVDRLARDSVVARIATLVEQ
ASQTKARTQLFIEKVEQRYSIGMVAVTLAVFAVPPLWGETLQRALLRAMTFMIVASPCAVVLATMPPLLAAIANAGRHGV
LAKSAIVMEQLGTTTRIAFDKTGTLTRGTPELAGIWVYERRFTDDELLRLAAAAEYPSEHPLGAAIVKAAQSRRIRLPTV
GEFTAHPGCRVTARVDGHVIAVGSATALLGTAGAAALEASMITAVDFLQGEGYTVVVVVCDSHPVGLLAITDQLRPEAAA
AISAATKLTGAKPVLLTGDNRATADRLGVQVGIDDVRAGLLPDDKVAAVRQLQAGGARLTVVGDGINDAPALAAAHVGIA
MGSARSELTLQTADAVVVRDDLTTIPTVIAMSRRARRIVVANLIVAVTFIAGLVVWDLAFTLPLPLGVARHEGSTIIVGL
NGLRLLRHTAWRRAAGTAHR
>Mature_659_residues
AVRELSPARCTSASPLVLARRTKLFALSEMRWAALALGLFSAGLLTQLCGAPQWVRWALFLACYATGGWEPGLAGLQALQ
RRTLDVDLLMVVAAIGAAAIGQIAEGALLIVIFATSGALEALVTARTADSVRGLMGLAPGTATRVGAGGGEETVNAADLR
IGDIVLVRPGERISADATVLAGGSEVDQATVTGEPLPVDKSIGDQVFAGTVNGTGALRIRVDRLARDSVVARIATLVEQA
SQTKARTQLFIEKVEQRYSIGMVAVTLAVFAVPPLWGETLQRALLRAMTFMIVASPCAVVLATMPPLLAAIANAGRHGVL
AKSAIVMEQLGTTTRIAFDKTGTLTRGTPELAGIWVYERRFTDDELLRLAAAAEYPSEHPLGAAIVKAAQSRRIRLPTVG
EFTAHPGCRVTARVDGHVIAVGSATALLGTAGAAALEASMITAVDFLQGEGYTVVVVVCDSHPVGLLAITDQLRPEAAAA
ISAATKLTGAKPVLLTGDNRATADRLGVQVGIDDVRAGLLPDDKVAAVRQLQAGGARLTVVGDGINDAPALAAAHVGIAM
GSARSELTLQTADAVVVRDDLTTIPTVIAMSRRARRIVVANLIVAVTFIAGLVVWDLAFTLPLPLGVARHEGSTIIVGLN
GLRLLRHTAWRRAAGTAHR

Specific function: Involved In Export Of Lead, Cadmium, Zinc And Mercury. [C]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=671, Percent_Identity=29.5081967213115, Blast_Score=246, Evalue=6e-65,
Organism=Homo sapiens, GI55743071, Length=655, Percent_Identity=29.3129770992366, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI55743073, Length=549, Percent_Identity=29.8724954462659, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI51944966, Length=340, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI237681111, Length=270, Percent_Identity=30, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI21361181, Length=270, Percent_Identity=30, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI237681109, Length=270, Percent_Identity=30, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI22748667, Length=279, Percent_Identity=27.2401433691756, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI83700225, Length=352, Percent_Identity=24.7159090909091, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI153946397, Length=275, Percent_Identity=29.4545454545455, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI4502271, Length=280, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789879, Length=562, Percent_Identity=36.8327402135231, Blast_Score=271, Evalue=1e-73,
Organism=Escherichia coli, GI1786691, Length=555, Percent_Identity=33.6936936936937, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1786914, Length=482, Percent_Identity=31.3278008298755, Blast_Score=132, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17556548, Length=576, Percent_Identity=28.9930555555556, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17557486, Length=248, Percent_Identity=26.2096774193548, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320475, Length=549, Percent_Identity=28.5974499089253, Blast_Score=193, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6319772, Length=574, Percent_Identity=28.397212543554, Blast_Score=177, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6325221, Length=598, Percent_Identity=25.0836120401338, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321430, Length=515, Percent_Identity=24.2718446601942, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321271, Length=195, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221329854, Length=405, Percent_Identity=26.6666666666667, Blast_Score=119, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR001366
- InterPro:   IPR006404
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.3 [C]

Molecular weight: Translated: 68646; Mature: 68514

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRELSPARCTSASPLVLARRTKLFALSEMRWAALALGLFSAGLLTQLCGAPQWVRWAL
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FLACYATGGWEPGLAGLQALQRRTLDVDLLMVVAAIGAAAIGQIAEGALLIVIFATSGAL
HHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHH
EALVTARTADSVRGLMGLAPGTATRVGAGGGEETVNAADLRIGDIVLVRPGERISADATV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCCCEEE
LAGGSEVDQATVTGEPLPVDKSIGDQVFAGTVNGTGALRIRVDRLARDSVVARIATLVEQ
EECCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHH
ASQTKARTQLFIEKVEQRYSIGMVAVTLAVFAVPPLWGETLQRALLRAMTFMIVASPCAV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLATMPPLLAAIANAGRHGVLAKSAIVMEQLGTTTRIAFDKTGTLTRGTPELAGIWVYER
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEEE
RFTDDELLRLAAAAEYPSEHPLGAAIVKAAQSRRIRLPTVGEFTAHPGCRVTARVDGHVI
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEECCCCCCCCCCCCCEEEEEECCEEE
AVGSATALLGTAGAAALEASMITAVDFLQGEGYTVVVVVCDSHPVGLLAITDQLRPEAAA
EECCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCHHHHH
AISAATKLTGAKPVLLTGDNRATADRLGVQVGIDDVRAGLLPDDKVAAVRQLQAGGARLT
HHHHHHHCCCCCEEEEECCCCCCHHHCCEEECHHHHHCCCCCCHHHHHHHHHHCCCCEEE
VVGDGINDAPALAAAHVGIAMGSARSELTLQTADAVVVRDDLTTIPTVIAMSRRARRIVV
EEECCCCCCHHHHHHHHHHEECCCCCCEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHH
ANLIVAVTFIAGLVVWDLAFTLPLPLGVARHEGSTIIVGLNGLRLLRHTAWRRAAGTAHR
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AVRELSPARCTSASPLVLARRTKLFALSEMRWAALALGLFSAGLLTQLCGAPQWVRWAL
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FLACYATGGWEPGLAGLQALQRRTLDVDLLMVVAAIGAAAIGQIAEGALLIVIFATSGAL
HHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHH
EALVTARTADSVRGLMGLAPGTATRVGAGGGEETVNAADLRIGDIVLVRPGERISADATV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCCCEEE
LAGGSEVDQATVTGEPLPVDKSIGDQVFAGTVNGTGALRIRVDRLARDSVVARIATLVEQ
EECCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHH
ASQTKARTQLFIEKVEQRYSIGMVAVTLAVFAVPPLWGETLQRALLRAMTFMIVASPCAV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLATMPPLLAAIANAGRHGVLAKSAIVMEQLGTTTRIAFDKTGTLTRGTPELAGIWVYER
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEEE
RFTDDELLRLAAAAEYPSEHPLGAAIVKAAQSRRIRLPTVGEFTAHPGCRVTARVDGHVI
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEECCCCCCCCCCCCCEEEEEECCEEE
AVGSATALLGTAGAAALEASMITAVDFLQGEGYTVVVVVCDSHPVGLLAITDQLRPEAAA
EECCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCHHHHH
AISAATKLTGAKPVLLTGDNRATADRLGVQVGIDDVRAGLLPDDKVAAVRQLQAGGARLT
HHHHHHHCCCCCEEEEECCCCCCHHHCCEEECHHHHHCCCCCCHHHHHHHHHHCCCCEEE
VVGDGINDAPALAAAHVGIAMGSARSELTLQTADAVVVRDDLTTIPTVIAMSRRARRIVV
EEECCCCCCHHHHHHHHHHEECCCCCCEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHH
ANLIVAVTFIAGLVVWDLAFTLPLPLGVARHEGSTIIVGLNGLRLLRHTAWRRAAGTAHR
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]