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The map label for this gene is atpD [H]

Identifier: 148661098

GI number: 148661098

Start: 1467151

End: 1468611

Strand: Direct

Name: atpD [H]

Synonym: MRA_1318

Alternate gene names: 148661098

Gene position: 1467151-1468611 (Clockwise)

Preceding gene: 148661097

Following gene: 148661099

Centisome position: 33.19

GC content: 63.52

Gene sequence:

>1461_bases
ATGACTACCACTGCCGAAAAGACCGACCGGCCGGGAAAGCCGGGAAGCTCCGACACCAGCGGCCGCGTGGTACGGGTCAC
TGGGCCCGTCGTCGACGTCGAGTTTCCTCGCGGTTCCATCCCCGAGCTGTTCAATGCACTGCACGCTGAGATCACCTTCG
AGTCGCTGGCGAAAACCCTCACCTTGGAGGTGGCGCAGCACCTCGGCGACAACCTGGTGCGCACCATCTCGCTGCAGCCG
ACCGACGGCTTGGTGCGCGGCGTCGAGGTGATCGACACCGGGAGGTCGATCTCGGTGCCGGTCGGTGAGGGTGTGAAGGG
CCACGTCTTCAATGCGCTGGGAGATTGCCTGGACGAGCCGGGATATGGCGAAAAATTCGAACACTGGTCGATTCACCGCA
AGCCGCCGGCGTTCGAGGAGCTGGAGCCTCGGACCGAGATGCTCGAGACCGGTCTGAAGGTGGTCGACCTGCTGACTCCG
TATGTTCGTGGCGGCAAGATCGCACTGTTCGGCGGTGCCGGGGTGGGCAAGACGGTGCTGATTCAGGAGATGATCAACCG
CATCGCCCGTAACTTCGGTGGTACGTCGGTGTTCGCCGGAGTGGGCGAGCGCACCCGCGAGGGCAACGATCTGTGGGTCG
AGCTTGCCGAAGCCAACGTGCTCAAGGACACCGCGCTGGTATTCGGACAGATGGACGAGCCGCCGGGCACCCGTATGCGT
GTTGCGCTGTCTGCGCTGACGATGGCGGAGTGGTTCCGTGACGAGCAGGGTCAAGACGTATTGCTGTTCATCGACAACAT
CTTCCGGTTCACCCAGGCTGGGTCGGAAGTGTCGACGCTTCTCGGCCGGATGCCGTCGGCCGTGGGATACCAGCCCACGC
TGGCCGACGAGATGGGCGAGCTGCAGGAGCGCATCACCTCGACGCGGGGACGCTCGATCACGTCGATGCAAGCCGTCTAC
GTGCCCGCCGACGACTACACCGACCCAGCGCCGGCGACCACGTTCGCCCACCTGGACGCCACGACCGAGCTATCCCGTGC
GGTGTTCTCCAAGGGCATCTTCCCCGCCGTGGACCCGCTGGCGTCCAGCTCGACCATCCTGGACCCCAGCGTTGTCGGGG
ATGAGCACTACCGCGTGGCCCAGGAAGTCATCCGGATCCTGCAGCGTTACAAGGACCTTCAGGACATTATCGCGATCCTC
GGTATCGACGAGTTGTCGGAGGAGGACAAGCAGCTGGTGAACCGCGCCCGGCGTATCGAGCGGTTCCTATCGCAGAACAT
GATGGCAGCCGAACAGTTCACCGGCCAGCCGGGTTCGACCGTCCCGGTGAAGGAGACCATTGAAGCGTTCGACCGCTTGT
GCAAGGGCGATTTCGATCACGTACCCGAACAGGCCTTCTTCTTGATCGGTGGCCTTGATGACCTGGCCAAGAAAGCCGAG
AGTCTCGGCGCCAAGCTGTGA

Upstream 100 bases:

>100_bases
GATCACCCAGGAGATTAGTGAAATCGTCGGTGGCGCAAATGCGCTCGCCGAAGCCCGCTAGGCCCAAGCTAGGTTAGCCC
CACGAGGAAGCGAAGAAGAT

Downstream 100 bases:

>100_bases
CGGGAGTTGTGGCATGGCCGAATTGAACGTTGAGATCGTCGCCGTCGACCGGAACATCTGGTCGGGTACGGCGAAGTTTC
TGTTCACCCGCACCACCGTC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MTTTAEKTDRPGKPGSSDTSGRVVRVTGPVVDVEFPRGSIPELFNALHAEITFESLAKTLTLEVAQHLGDNLVRTISLQP
TDGLVRGVEVIDTGRSISVPVGEGVKGHVFNALGDCLDEPGYGEKFEHWSIHRKPPAFEELEPRTEMLETGLKVVDLLTP
YVRGGKIALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELAEANVLKDTALVFGQMDEPPGTRMR
VALSALTMAEWFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVY
VPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILDPSVVGDEHYRVAQEVIRILQRYKDLQDIIAIL
GIDELSEEDKQLVNRARRIERFLSQNMMAAEQFTGQPGSTVPVKETIEAFDRLCKGDFDHVPEQAFFLIGGLDDLAKKAE
SLGAKL

Sequences:

>Translated_486_residues
MTTTAEKTDRPGKPGSSDTSGRVVRVTGPVVDVEFPRGSIPELFNALHAEITFESLAKTLTLEVAQHLGDNLVRTISLQP
TDGLVRGVEVIDTGRSISVPVGEGVKGHVFNALGDCLDEPGYGEKFEHWSIHRKPPAFEELEPRTEMLETGLKVVDLLTP
YVRGGKIALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELAEANVLKDTALVFGQMDEPPGTRMR
VALSALTMAEWFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVY
VPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILDPSVVGDEHYRVAQEVIRILQRYKDLQDIIAIL
GIDELSEEDKQLVNRARRIERFLSQNMMAAEQFTGQPGSTVPVKETIEAFDRLCKGDFDHVPEQAFFLIGGLDDLAKKAE
SLGAKL
>Mature_485_residues
TTTAEKTDRPGKPGSSDTSGRVVRVTGPVVDVEFPRGSIPELFNALHAEITFESLAKTLTLEVAQHLGDNLVRTISLQPT
DGLVRGVEVIDTGRSISVPVGEGVKGHVFNALGDCLDEPGYGEKFEHWSIHRKPPAFEELEPRTEMLETGLKVVDLLTPY
VRGGKIALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELAEANVLKDTALVFGQMDEPPGTRMRV
ALSALTMAEWFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVYV
PADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILDPSVVGDEHYRVAQEVIRILQRYKDLQDIIAILG
IDELSEEDKQLVNRARRIERFLSQNMMAAEQFTGQPGSTVPVKETIEAFDRLCKGDFDHVPEQAFFLIGGLDDLAKKAES
LGAKL

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=475, Percent_Identity=60.4210526315789, Blast_Score=567, Evalue=1e-162,
Organism=Homo sapiens, GI19913424, Length=338, Percent_Identity=28.698224852071, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI19913426, Length=356, Percent_Identity=23.5955056179775, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI19913428, Length=359, Percent_Identity=23.6768802228412, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI50345984, Length=358, Percent_Identity=26.536312849162, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4757810, Length=358, Percent_Identity=26.536312849162, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1790170, Length=463, Percent_Identity=58.963282937365, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI1788251, Length=396, Percent_Identity=28.7878787878788, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1790172, Length=443, Percent_Identity=25.2821670428894, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25144756, Length=479, Percent_Identity=59.2901878914405, Blast_Score=556, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI17565854, Length=338, Percent_Identity=28.698224852071, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=352, Percent_Identity=23.2954545454545, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17570191, Length=352, Percent_Identity=23.2954545454545, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=357, Percent_Identity=26.0504201680672, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71988080, Length=357, Percent_Identity=26.0504201680672, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71988074, Length=342, Percent_Identity=24.8538011695906, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322581, Length=465, Percent_Identity=60.8602150537634, Blast_Score=560, Evalue=1e-160,
Organism=Saccharomyces cerevisiae, GI6319370, Length=369, Percent_Identity=27.10027100271, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6319603, Length=428, Percent_Identity=25.4672897196262, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6320016, Length=252, Percent_Identity=25.7936507936508, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24638766, Length=469, Percent_Identity=60.1279317697228, Blast_Score=561, Evalue=1e-160,
Organism=Drosophila melanogaster, GI28574560, Length=488, Percent_Identity=57.3770491803279, Blast_Score=541, Evalue=1e-154,
Organism=Drosophila melanogaster, GI20129479, Length=324, Percent_Identity=28.0864197530864, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24583992, Length=323, Percent_Identity=28.1733746130031, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24583988, Length=327, Percent_Identity=27.82874617737, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24583986, Length=327, Percent_Identity=27.82874617737, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24583984, Length=327, Percent_Identity=27.82874617737, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281361666, Length=360, Percent_Identity=25.5555555555556, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646341, Length=360, Percent_Identity=25.5555555555556, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17136796, Length=360, Percent_Identity=25.5555555555556, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24658560, Length=357, Percent_Identity=24.9299719887955, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24638768, Length=95, Percent_Identity=46.3157894736842, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 53095; Mature: 52964

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTAEKTDRPGKPGSSDTSGRVVRVTGPVVDVEFPRGSIPELFNALHAEITFESLAKTL
CCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
TLEVAQHLGDNLVRTISLQPTDGLVRGVEVIDTGRSISVPVGEGVKGHVFNALGDCLDEP
HHHHHHHCCCCCEEEEECCCCCHHHHCHHHEECCCEEECCCCCCCCHHHHHHHHHHHCCC
GYGEKFEHWSIHRKPPAFEELEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVL
CCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
IQEMINRIARNFGGTSVFAGVGERTREGNDLWVELAEANVLKDTALVFGQMDEPPGTRMR
HHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCHHH
VALSALTMAEWFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGE
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCHHHHHHHH
LQERITSTRGRSITSMQAVYVPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPL
HHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEHHCCHHHHHHHHHHHCCCCCCCCCC
ASSSTILDPSVVGDEHYRVAQEVIRILQRYKDLQDIIAILGIDELSEEDKQLVNRARRIE
CCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHH
RFLSQNMMAAEQFTGQPGSTVPVKETIEAFDRLCKGDFDHVPEQAFFLIGGLDDLAKKAE
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHCCCHHHEEEECCHHHHHHHHH
SLGAKL
HHCCCC
>Mature Secondary Structure 
TTTAEKTDRPGKPGSSDTSGRVVRVTGPVVDVEFPRGSIPELFNALHAEITFESLAKTL
CCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
TLEVAQHLGDNLVRTISLQPTDGLVRGVEVIDTGRSISVPVGEGVKGHVFNALGDCLDEP
HHHHHHHCCCCCEEEEECCCCCHHHHCHHHEECCCEEECCCCCCCCHHHHHHHHHHHCCC
GYGEKFEHWSIHRKPPAFEELEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVL
CCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
IQEMINRIARNFGGTSVFAGVGERTREGNDLWVELAEANVLKDTALVFGQMDEPPGTRMR
HHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCHHH
VALSALTMAEWFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGE
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCHHHHHHHH
LQERITSTRGRSITSMQAVYVPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPL
HHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEHHCCHHHHHHHHHHHCCCCCCCCCC
ASSSTILDPSVVGDEHYRVAQEVIRILQRYKDLQDIIAILGIDELSEEDKQLVNRARRIE
CCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHH
RFLSQNMMAAEQFTGQPGSTVPVKETIEAFDRLCKGDFDHVPEQAFFLIGGLDDLAKKAE
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHCCCHHHEEEECCHHHHHHHHH
SLGAKL
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA