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The map label for this gene is secY

Identifier: 148660507

GI number: 148660507

Start: 826106

End: 827431

Strand: Direct

Name: secY

Synonym: MRA_0740

Alternate gene names: 148660507

Gene position: 826106-827431 (Clockwise)

Preceding gene: 148660505

Following gene: 148660508

Centisome position: 18.69

GC content: 59.65

Gene sequence:

>1326_bases
GTGCTTTCGGCTTTCATCTCGTCGCTGCGAACAGTCGACTTGAGACGAAAGATCCTCTTCACGCTGGGCATCGTCATTCT
CTACCGTGTCGGTGCCGCGCTGCCGTCCCCCGGTGTCAATTTTCCGAACGTGCAGCAGTGCATCAAAGAAGCCAGCGCGG
GCGAAGCCGGACAGATCTATTCCCTGATCAACCTGTTCTCCGGCGGTGCGTTATTAAAGCTCACGGTGTTCGCGGTGGGG
GTGATGCCCTACATCACCGCCAGCATCATCGTGCAGCTGCTCACCGTGGTCATCCCGAGGTTCGAGGAACTCCGGAAGGA
AGGCCAGGCGGGTCAGTCGAAGATGACCCAGTACACCCGTTACCTAGCGATCGCGTTGGCTATCCTTCAAGCCACCAGCA
TCGTGGCGTTGGCTGCCAACGGCGGGTTGCTACAAGGTTGCTCGCTGGACATCATCGCCGACCAGAGCATTTTCACACTG
GTCGTCATCGTGCTCGTGATGACGGGCGGCGCCGCGTTGGTGATGTGGATGGGCGAGTTGATCACCGAACGCGGCATCGG
CAACGGCATGTCGCTGCTGATCTTCGTTGGCATCGCTGCCCGCATCCCGGCCGAAGGTCAAAGCATCCTGGAAAGCCGCG
GTGGAGTCGTCTTCACCGCGGTCTGCGCGGCCGCGTTGATCATCATCGTCGGTGTGGTGTTCGTCGAACAGGGTCAGCGC
CGGATTCCAGTGCAATACGCCAAGCGCATGGTGGGCCGGCGGATGTATGGCGGGACTTCGACTTATCTGCCGCTCAAGGT
CAACCAGGCCGGCGTTATCCCGGTTATCTTCGCGTCGTCGCTGATCTACATTCCGCACCTGATCACCCAGCTGATTCGCA
GCGGCAGCGGTGTCGTGGGAAACAGCTGGTGGGACAAATTCGTCGGCACGTACCTGTCCGACCCGAGCAACCTGGTCTAC
ATCGGCATCTACTTCGGCCTCATCATCTTCTTCACCTACTTCTACGTGTCGATCACCTTCAACCCCGACGAACGTGCCGA
CGAGATGAAGAAGTTCGGCGGCTTCATTCCGGGAATTCGGCCGGGCCGTCCGACCGCAGACTATCTGCGCTATGTGCTGA
GCCGGATTACCTTGCCGGGCTCGATTTACCTCGGCGTGATCGCCGTGCTGCCCAACCTGTTCCTCCAGATCGGCGCCGGT
GGAACCGTGCAGAACCTGCCCTTTGGGGGTACCGCGGTGCTGATCATGATCGGTGTCGGTTTGGATACGGTCAAGCAGAT
CGAGAGTCAGCTCATGCAGCGCAACTACGAAGGGTTCCTCAAGTGA

Upstream 100 bases:

>100_bases
GTTAGTCTCTTACACGATTTGGCGCGCGACGCCGTACGTCCTGGCCTGCGGGTGTTGGGCGCGTGATGCAAGATGACCCC
GGGCTGCGCAGGAGGATAGA

Downstream 100 bases:

>100_bases
GAGTTTTGTTGCTGGGACCGCCCGGGGCGGGCAAGGGGACGCAGGCGGTGAAGCTGGCCGAGAAGCTCGGGATCCCGCAG
ATCTCCACCGGCGAACTCTT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MLSAFISSLRTVDLRRKILFTLGIVILYRVGAALPSPGVNFPNVQQCIKEASAGEAGQIYSLINLFSGGALLKLTVFAVG
VMPYITASIIVQLLTVVIPRFEELRKEGQAGQSKMTQYTRYLAIALAILQATSIVALAANGGLLQGCSLDIIADQSIFTL
VVIVLVMTGGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGQSILESRGGVVFTAVCAAALIIIVGVVFVEQGQR
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLIRSGSGVVGNSWWDKFVGTYLSDPSNLVY
IGIYFGLIIFFTYFYVSITFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGSIYLGVIAVLPNLFLQIGAG
GTVQNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK

Sequences:

>Translated_441_residues
MLSAFISSLRTVDLRRKILFTLGIVILYRVGAALPSPGVNFPNVQQCIKEASAGEAGQIYSLINLFSGGALLKLTVFAVG
VMPYITASIIVQLLTVVIPRFEELRKEGQAGQSKMTQYTRYLAIALAILQATSIVALAANGGLLQGCSLDIIADQSIFTL
VVIVLVMTGGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGQSILESRGGVVFTAVCAAALIIIVGVVFVEQGQR
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLIRSGSGVVGNSWWDKFVGTYLSDPSNLVY
IGIYFGLIIFFTYFYVSITFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGSIYLGVIAVLPNLFLQIGAG
GTVQNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK
>Mature_441_residues
MLSAFISSLRTVDLRRKILFTLGIVILYRVGAALPSPGVNFPNVQQCIKEASAGEAGQIYSLINLFSGGALLKLTVFAVG
VMPYITASIIVQLLTVVIPRFEELRKEGQAGQSKMTQYTRYLAIALAILQATSIVALAANGGLLQGCSLDIIADQSIFTL
VVIVLVMTGGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGQSILESRGGVVFTAVCAAALIIIVGVVFVEQGQR
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLIRSGSGVVGNSWWDKFVGTYLSDPSNLVY
IGIYFGLIIFFTYFYVSITFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGSIYLGVIAVLPNLFLQIGAG
GTVQNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family

Homologues:

Organism=Escherichia coli, GI1789696, Length=437, Percent_Identity=42.1052631578947, Blast_Score=293, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECY_MYCBO (P0A5Z3)

Other databases:

- EMBL:   U77912
- EMBL:   BX248336
- RefSeq:   NP_854411.1
- ProteinModelPortal:   P0A5Z3
- EnsemblBacteria:   EBMYCT00000016347
- GeneID:   1094170
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0753
- GeneTree:   EBGT00050000017046
- HOGENOM:   HBG565931
- OMA:   FAQSIMF
- ProtClustDB:   PRK09204
- BioCyc:   MBOV233413:MB0753-MONOMER
- InterPro:   IPR002208
- InterPro:   IPR023201
- PANTHER:   PTHR10906
- PIRSF:   PIRSF004557
- PRINTS:   PR00303
- TIGRFAMs:   TIGR00967

Pfam domain/function: PF00344 SecY; SSF103491 SecY

EC number: NA

Molecular weight: Translated: 47612; Mature: 47612

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS00755 SECY_1; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c88e6b8)-; HASH(0x1d1cbf4c)-; HASH(0x1d1adb48)-; HASH(0x1b3f9b8c)-; HASH(0x1cac6778)-; HASH(0x1d2e6e4c)-; HASH(0x1c0b84ac)-; HASH(0x1add68b8)-; HASH(0x1cec4af0)-; HASH(0x1d2f8ee8)-; HASH(0x1c42b238)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAFISSLRTVDLRRKILFTLGIVILYRVGAALPSPGVNFPNVQQCIKEASAGEAGQIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHH
SLINLFSGGALLKLTVFAVGVMPYITASIIVQLLTVVIPRFEELRKEGQAGQSKMTQYTR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
YLAIALAILQATSIVALAANGGLLQGCSLDIIADQSIFTLVVIVLVMTGGAALVMWMGEL
HHHHHHHHHHHHHHEEEECCCCEECCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHH
ITERGIGNGMSLLIFVGIAARIPAEGQSILESRGGVVFTAVCAAALIIIVGVVFVEQGQR
HHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCC
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLIRSGSGVVG
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NSWWDKFVGTYLSDPSNLVYIGIYFGLIIFFTYFYVSITFNPDERADEMKKFGGFIPGIR
CHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCC
PGRPTADYLRYVLSRITLPGSIYLGVIAVLPNLFLQIGAGGTVQNLPFGGTAVLIMIGVG
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHEECCC
LDTVKQIESQLMQRNYEGFLK
HHHHHHHHHHHHHCCHHHCCH
>Mature Secondary Structure
MLSAFISSLRTVDLRRKILFTLGIVILYRVGAALPSPGVNFPNVQQCIKEASAGEAGQIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHH
SLINLFSGGALLKLTVFAVGVMPYITASIIVQLLTVVIPRFEELRKEGQAGQSKMTQYTR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
YLAIALAILQATSIVALAANGGLLQGCSLDIIADQSIFTLVVIVLVMTGGAALVMWMGEL
HHHHHHHHHHHHHHEEEECCCCEECCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHH
ITERGIGNGMSLLIFVGIAARIPAEGQSILESRGGVVFTAVCAAALIIIVGVVFVEQGQR
HHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCC
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLIRSGSGVVG
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NSWWDKFVGTYLSDPSNLVYIGIYFGLIIFFTYFYVSITFNPDERADEMKKFGGFIPGIR
CHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCC
PGRPTADYLRYVLSRITLPGSIYLGVIAVLPNLFLQIGAGGTVQNLPFGGTAVLIMIGVG
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHEECCC
LDTVKQIESQLMQRNYEGFLK
HHHHHHHHHHHHHCCHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9350347; 12788972