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The map label for this gene is atsD [H]

Identifier: 148660437

GI number: 148660437

Start: 757443

End: 759806

Strand: Direct

Name: atsD [H]

Synonym: MRA_0673

Alternate gene names: 148660437

Gene position: 757443-759806 (Clockwise)

Preceding gene: 148660429

Following gene: 148660438

Centisome position: 17.14

GC content: 64.26

Gene sequence:

>2364_bases
ATGCCGCAGCCAAGAACGCATCTGCCGATTCCCAGTGCTGCTCGCACCGGGCTGATCACGTATGACGCGAAGGATCCCGA
CAGCACCTATCCGCCGATCGAGCAGCTGCGCCCACCGGCGGGTGCCCCGAATGTGTTGCTGATCCTGCTTGACGATGTCG
GGTTCGGTGCGTCGAGCGCGTTCGGAGGCCCATGCAGGACGTCGACGGCGGAACTGCTTGCCGGTAACGGGTTGCGGTAC
AACCGGTTTCACACCACCGCGCTGTGCTCGCCGACGCGTCAGGCGTTGTTAACTGGACGCAACCATCACTCCGCCGGCAT
GGGCGGTATCACCGAAATCGCCACCGGTGCACCGGGATACAGCTCAGTACTACCGAACACCATGTCGCCGATCGCGCGGA
CGCTAAAGCTCAACGGCTACAACACCGCCCAGTTCGGCAAGTGCCACGAAGTCCCGGTCTGGCAGACCAGCCCGGTCGGG
CCGTTCGACGCGTGGCCCAGCGGCGGCGGTGGTTTCGAATACTTCTACGGGTTTATCGGTGGCGAGGCTAACCAGTGGTA
TCCGAGTCTGTACGAGGGCACCACGCCGGTCGAGGTGAACCGCACGCCCGAGGAGGGTTACCATTTCATGGCGGACATGA
CCGACAAGGCCCTCGGCTGGATCGGACAGCAGAAGGCACTGGCCCCCGACCGGCCGTTCTTCGTGTACTTCGCCCCGGGC
GCCACCCACGCGCCCCACCACGTTCCGCGGGAGTGGGCCGACAAGTACCGGGGCCGCTTCGATGTGGGCTGGGACGCACT
GCGAGAGGAAACCTTCGCCCGGCAAAAGGAACTCGGGGTGATCCCGGCGGACTGCCAGCTGACCGCGCGGCACGCCGAAA
TCCCGGCGTGGGACGACATGCCGGAGGACCTCAAACCCGTGCTATGCCGGCAGATGGAGGTCTACGCGGGCTTTCTGGAA
TACACCGACCACCACGTCGGCCGGCTCGTCGACGGCCTGCAGCGCCTCGGTGTGCTCGACGACACGCTGGTGTTCTACAT
CATCGACGACAACGGCGCCTCGGCCGAGGGCACGATCAACGGCACCTACAACGAGATGTTGAACTTCAACGGCCTGGCCG
ACATCGAGACGCCGCGGTTCATGACCGACCGGCTCGACAAGTTCGGCGGGCCGGAGTCCTACAACCACTATTCGGTGGGT
TGGGCGCATGCGATGGATACCCCCTATCAGTGGACCAAACAAGTGGCCTCGCACTGGGGTGGCACGCGTAACGGCACGAT
TGTGCACTGGCCCAACGGAATTGCCGCCAAGGGGGAGATGCGCTGGCAGTTTCACCACGTCATCGACGTGGCGCCGACCA
TCCTGGAGGCGGCGGGGTTGCCGGAACCGTTATTCGTCAACGGCGTGCAGCAACACCCCATCGAAGGGGTCAGCATGGCC
TATTCGTTCGACGACGCGCAGGCGCCGGATCGGCACGAGACGCAGTATTTCGAGATGTTCGGAAACCGGGGCATCTACCA
CAAGGGTTGGACCGCGGTGACCAAGCACAAGACGCCGTGGATTTTGGTTGGCGAGCAGACCGTCGCGTTCGACGACGACG
TGTGGGAGCTCTACGACACCACCAAGGATTGGAGCCAGGCCAAAGACTTGGCCAAGGAGATGCCGGAAAAGCTGCATGAG
CTGCAGCGGCTGTGGCTGATCGAGGCGACGCGCTACAACGTGCTTCCGCTGGACGACGACACCGCCAGCCGCATCAACCC
CGATCTGGCGGGCAGGCCGGTGCTCATCAGGGGCAACACCCAGGTGCTGTTTTCGAACATGGGCCGGTTGTCGGAGAACT
GTGTGCTCAACCTCAAGAACAAATCGCACACGGTGACCGCTGAGGTCGAGGTGCCCGAGACCGGTGCTGAGGGCGTGATC
GTCGCGCAGGGCGCCAGCATCGGCGGCTGGAGCCTGTATGCCAACGACGGCAAGCTCAAGTACTGCTACAACCTGGGTGG
TATCAAGCACTTCTACGCCGAGTCCGCCGACCCGCTGCCGGCCGGCGCCCATCAGGTGCGCATGGAATTCGCTTATGCCG
GTGGCGGTTTGGGCAAGGGCGGCGAGGTAACTCTTTATGTCGACGGCCAACAGGTCGGCGAAGGACATGTCGAAGCCACC
CTTGCCATCGTCTTCTCGGCCGACGACGGCTGCGATGTCGGCATGGATTCGGGCTCGCCCGTCTCACCCGACTATGCCCC
GGGGAGTAACGCGTTCAACGGGCGGATCAAGGGCGTGCAGCTCGCGATCGCCGAGGCCGCCGCTGCTGCGGGCCATCTGG
TCGACCCGGAGCACGCGATCCGCATCGCGCTGGCGCGCCAATAG

Upstream 100 bases:

>100_bases
TGAAATTTGGGCGGCGGCTGCCATTGCGGTCGCGTTGACCCGCGGACGGCCCAGACGCTGCGGTTGTAGCGTCGATAGGC
ACGCGTATTAGGGAGGAACA

Downstream 100 bases:

>100_bases
GGCCGCACAGTCAAACGGGGAGGGGACGGCGATGGAAAAGTCACGGTGCCACGCTGTCGCACATGGAGGTGGGTGTGCGG
GATCTGCGAAATCGCACAAG

Product: putative arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 787; Mature: 786

Protein sequence:

>787_residues
MPQPRTHLPIPSAARTGLITYDAKDPDSTYPPIEQLRPPAGAPNVLLILLDDVGFGASSAFGGPCRTSTAELLAGNGLRY
NRFHTTALCSPTRQALLTGRNHHSAGMGGITEIATGAPGYSSVLPNTMSPIARTLKLNGYNTAQFGKCHEVPVWQTSPVG
PFDAWPSGGGGFEYFYGFIGGEANQWYPSLYEGTTPVEVNRTPEEGYHFMADMTDKALGWIGQQKALAPDRPFFVYFAPG
ATHAPHHVPREWADKYRGRFDVGWDALREETFARQKELGVIPADCQLTARHAEIPAWDDMPEDLKPVLCRQMEVYAGFLE
YTDHHVGRLVDGLQRLGVLDDTLVFYIIDDNGASAEGTINGTYNEMLNFNGLADIETPRFMTDRLDKFGGPESYNHYSVG
WAHAMDTPYQWTKQVASHWGGTRNGTIVHWPNGIAAKGEMRWQFHHVIDVAPTILEAAGLPEPLFVNGVQQHPIEGVSMA
YSFDDAQAPDRHETQYFEMFGNRGIYHKGWTAVTKHKTPWILVGEQTVAFDDDVWELYDTTKDWSQAKDLAKEMPEKLHE
LQRLWLIEATRYNVLPLDDDTASRINPDLAGRPVLIRGNTQVLFSNMGRLSENCVLNLKNKSHTVTAEVEVPETGAEGVI
VAQGASIGGWSLYANDGKLKYCYNLGGIKHFYAESADPLPAGAHQVRMEFAYAGGGLGKGGEVTLYVDGQQVGEGHVEAT
LAIVFSADDGCDVGMDSGSPVSPDYAPGSNAFNGRIKGVQLAIAEAAAAAGHLVDPEHAIRIALARQ

Sequences:

>Translated_787_residues
MPQPRTHLPIPSAARTGLITYDAKDPDSTYPPIEQLRPPAGAPNVLLILLDDVGFGASSAFGGPCRTSTAELLAGNGLRY
NRFHTTALCSPTRQALLTGRNHHSAGMGGITEIATGAPGYSSVLPNTMSPIARTLKLNGYNTAQFGKCHEVPVWQTSPVG
PFDAWPSGGGGFEYFYGFIGGEANQWYPSLYEGTTPVEVNRTPEEGYHFMADMTDKALGWIGQQKALAPDRPFFVYFAPG
ATHAPHHVPREWADKYRGRFDVGWDALREETFARQKELGVIPADCQLTARHAEIPAWDDMPEDLKPVLCRQMEVYAGFLE
YTDHHVGRLVDGLQRLGVLDDTLVFYIIDDNGASAEGTINGTYNEMLNFNGLADIETPRFMTDRLDKFGGPESYNHYSVG
WAHAMDTPYQWTKQVASHWGGTRNGTIVHWPNGIAAKGEMRWQFHHVIDVAPTILEAAGLPEPLFVNGVQQHPIEGVSMA
YSFDDAQAPDRHETQYFEMFGNRGIYHKGWTAVTKHKTPWILVGEQTVAFDDDVWELYDTTKDWSQAKDLAKEMPEKLHE
LQRLWLIEATRYNVLPLDDDTASRINPDLAGRPVLIRGNTQVLFSNMGRLSENCVLNLKNKSHTVTAEVEVPETGAEGVI
VAQGASIGGWSLYANDGKLKYCYNLGGIKHFYAESADPLPAGAHQVRMEFAYAGGGLGKGGEVTLYVDGQQVGEGHVEAT
LAIVFSADDGCDVGMDSGSPVSPDYAPGSNAFNGRIKGVQLAIAEAAAAAGHLVDPEHAIRIALARQ
>Mature_786_residues
PQPRTHLPIPSAARTGLITYDAKDPDSTYPPIEQLRPPAGAPNVLLILLDDVGFGASSAFGGPCRTSTAELLAGNGLRYN
RFHTTALCSPTRQALLTGRNHHSAGMGGITEIATGAPGYSSVLPNTMSPIARTLKLNGYNTAQFGKCHEVPVWQTSPVGP
FDAWPSGGGGFEYFYGFIGGEANQWYPSLYEGTTPVEVNRTPEEGYHFMADMTDKALGWIGQQKALAPDRPFFVYFAPGA
THAPHHVPREWADKYRGRFDVGWDALREETFARQKELGVIPADCQLTARHAEIPAWDDMPEDLKPVLCRQMEVYAGFLEY
TDHHVGRLVDGLQRLGVLDDTLVFYIIDDNGASAEGTINGTYNEMLNFNGLADIETPRFMTDRLDKFGGPESYNHYSVGW
AHAMDTPYQWTKQVASHWGGTRNGTIVHWPNGIAAKGEMRWQFHHVIDVAPTILEAAGLPEPLFVNGVQQHPIEGVSMAY
SFDDAQAPDRHETQYFEMFGNRGIYHKGWTAVTKHKTPWILVGEQTVAFDDDVWELYDTTKDWSQAKDLAKEMPEKLHEL
QRLWLIEATRYNVLPLDDDTASRINPDLAGRPVLIRGNTQVLFSNMGRLSENCVLNLKNKSHTVTAEVEVPETGAEGVIV
AQGASIGGWSLYANDGKLKYCYNLGGIKHFYAESADPLPAGAHQVRMEFAYAGGGLGKGGEVTLYVDGQQVGEGHVEATL
AIVFSADDGCDVGMDSGSPVSPDYAPGSNAFNGRIKGVQLAIAEAAAAAGHLVDPEHAIRIALARQ

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI38569407, Length=332, Percent_Identity=22.5903614457831, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI38569405, Length=332, Percent_Identity=22.5903614457831, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI87081924, Length=362, Percent_Identity=23.4806629834254, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 86128; Mature: 85997

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQPRTHLPIPSAARTGLITYDAKDPDSTYPPIEQLRPPAGAPNVLLILLDDVGFGASSA
CCCCCCCCCCCCHHCCCEEEECCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCCCCC
FGGPCRTSTAELLAGNGLRYNRFHTTALCSPTRQALLTGRNHHSAGMGGITEIATGAPGY
CCCCCCCCHHHHHCCCCEEECEEEEEEECCHHHHHHHCCCCCCCCCCCCHHHHHCCCCCH
SSVLPNTMSPIARTLKLNGYNTAQFGKCHEVPVWQTSPVGPFDAWPSGGGGFEYFYGFIG
HHHCCCHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEC
GEANQWYPSLYEGTTPVEVNRTPEEGYHFMADMTDKALGWIGQQKALAPDRPFFVYFAPG
CCCCCCCCHHHCCCCCEEECCCCHHCCEEEHHHHHHHHHHCCCCCCCCCCCCEEEEECCC
ATHAPHHVPREWADKYRGRFDVGWDALREETFARQKELGVIPADCQLTARHAEIPAWDDM
CCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEECCCCEEEEECCCCCCCCCC
PEDLKPVLCRQMEVYAGFLEYTDHHVGRLVDGLQRLGVLDDTLVFYIIDDNGASAEGTIN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEC
GTYNEMLNFNGLADIETPRFMTDRLDKFGGPESYNHYSVGWAHAMDTPYQWTKQVASHWG
CCHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHCC
GTRNGTIVHWPNGIAAKGEMRWQFHHVIDVAPTILEAAGLPEPLFVNGVQQHPIEGVSMA
CCCCCEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCEECCHHHCCCCCEEEE
YSFDDAQAPDRHETQYFEMFGNRGIYHKGWTAVTKHKTPWILVGEQTVAFDDDVWELYDT
EECCCCCCCCCHHHHHHHHHCCCCCEECCCEEEECCCCCEEEECCEEEECCCCHHHHHHC
TKDWSQAKDLAKEMPEKLHELQRLWLIEATRYNVLPLDDDTASRINPDLAGRPVLIRGNT
CCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEECCCCCHHHCCCCCCCCEEEEECCC
QVLFSNMGRLSENCVLNLKNKSHTVTAEVEVPETGAEGVIVAQGASIGGWSLYANDGKLK
EEEEHHHCCCCCCEEEEECCCCEEEEEEEECCCCCCCEEEEECCCCCCCEEEEECCCCEE
YCYNLGGIKHFYAESADPLPAGAHQVRMEFAYAGGGLGKGGEVTLYVDGQQVGEGHVEAT
EEEECCCCHHHHHCCCCCCCCCCHHEEEEEEEECCCCCCCCEEEEEECCCCCCCCCEEEE
LAIVFSADDGCDVGMDSGSPVSPDYAPGSNAFNGRIKGVQLAIAEAAAAAGHLVDPEHAI
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECEEEEEEHHHHHHCCCCCCCCCEE
RIALARQ
EEEEECC
>Mature Secondary Structure 
PQPRTHLPIPSAARTGLITYDAKDPDSTYPPIEQLRPPAGAPNVLLILLDDVGFGASSA
CCCCCCCCCCCHHCCCEEEECCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCCCCC
FGGPCRTSTAELLAGNGLRYNRFHTTALCSPTRQALLTGRNHHSAGMGGITEIATGAPGY
CCCCCCCCHHHHHCCCCEEECEEEEEEECCHHHHHHHCCCCCCCCCCCCHHHHHCCCCCH
SSVLPNTMSPIARTLKLNGYNTAQFGKCHEVPVWQTSPVGPFDAWPSGGGGFEYFYGFIG
HHHCCCHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEC
GEANQWYPSLYEGTTPVEVNRTPEEGYHFMADMTDKALGWIGQQKALAPDRPFFVYFAPG
CCCCCCCCHHHCCCCCEEECCCCHHCCEEEHHHHHHHHHHCCCCCCCCCCCCEEEEECCC
ATHAPHHVPREWADKYRGRFDVGWDALREETFARQKELGVIPADCQLTARHAEIPAWDDM
CCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEECCCCEEEEECCCCCCCCCC
PEDLKPVLCRQMEVYAGFLEYTDHHVGRLVDGLQRLGVLDDTLVFYIIDDNGASAEGTIN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEC
GTYNEMLNFNGLADIETPRFMTDRLDKFGGPESYNHYSVGWAHAMDTPYQWTKQVASHWG
CCHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHCC
GTRNGTIVHWPNGIAAKGEMRWQFHHVIDVAPTILEAAGLPEPLFVNGVQQHPIEGVSMA
CCCCCEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCEECCHHHCCCCCEEEE
YSFDDAQAPDRHETQYFEMFGNRGIYHKGWTAVTKHKTPWILVGEQTVAFDDDVWELYDT
EECCCCCCCCCHHHHHHHHHCCCCCEECCCEEEECCCCCEEEECCEEEECCCCHHHHHHC
TKDWSQAKDLAKEMPEKLHELQRLWLIEATRYNVLPLDDDTASRINPDLAGRPVLIRGNT
CCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEECCCCCHHHCCCCCCCCEEEEECCC
QVLFSNMGRLSENCVLNLKNKSHTVTAEVEVPETGAEGVIVAQGASIGGWSLYANDGKLK
EEEEHHHCCCCCCEEEEECCCCEEEEEEEECCCCCCCEEEEECCCCCCCEEEEECCCCEE
YCYNLGGIKHFYAESADPLPAGAHQVRMEFAYAGGGLGKGGEVTLYVDGQQVGEGHVEAT
EEEECCCCHHHHHCCCCCCCCCCHHEEEEEEEECCCCCCCCEEEEEECCCCCCCCCEEEE
LAIVFSADDGCDVGMDSGSPVSPDYAPGSNAFNGRIKGVQLAIAEAAAAAGHLVDPEHAI
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECEEEEEEHHHHHHCCCCCCCCCEE
RIALARQ
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]