Click here to switch to the map view.

The map label for this gene is aspC

Identifier: 148660103

GI number: 148660103

Start: 403235

End: 404524

Strand: Reverse

Name: aspC

Synonym: MRA_0346

Alternate gene names: 148660103

Gene position: 404524-403235 (Counterclockwise)

Preceding gene: 148660104

Following gene: 148660101

Centisome position: 9.15

GC content: 64.34

Gene sequence:

>1290_bases
GTGGACAACGATGGCACCATTGTGGACGTGACAACCCACCAGCTGCCCTGGCACACCGCCAGCCATCAGCGGCAGCGCGC
CTTCGCTCAGTCGGCCAAGCTGCAGGACGTCCTGTACGAGATCCGCGGCCCGGTGCACCAGCACGCCGCGCGGCTCGAAG
CCGAAGGTCACCGCATCCTCAAACTCAACATCGGCAACCCGGCGCCGTTCGGCTTCGAAGCACCCGACGTGATCATGCGC
GATATCATCCAGGCGCTGCCCTACGCGCAGGGGTACTCCGACTCGCAGGGCATCCTGTCGGCCCGGCGTGCGGTGGTCAC
GCGCTACGAGCTGGTGCCCGGATTTCCCCGATTCGACGTGGACGACGTCTACCTGGGTAACGGGGTCTCCGAGCTGATCA
CGATGACGCTGCAAGCCCTGCTGGACAACGGCGATCAGGTGCTGATTCCATCACCGGACTACCCGCTGTGGACGGCGTCG
ACCTCGCTGGCTGGCGGCACTCCGGTCCACTACCTGTGCGATGAGACCCAAGGCTGGCAGCCCGATATCGCCGACCTGGA
ATCCAAGATCACCGAGCGCACCAAGGCGCTGGTCGTGATCAACCCCAACAACCCAACCGGCGCGGTGTACAGCTGCGAAA
TCCTCACCCAGATGGTCGATCTGGCCCGCAAGCATCAACTGCTGCTGTTGGCGGACGAAATCTACGACAAAATCCTCTAC
GACGACGCCAAGCACATCAGCCTGGCATCGATCGCCCCGGATATGTTGTGCCTGACCTTCAATGGGCTGTCGAAGGCCTA
CCGCGTCGCCGGATACCGGGCCGGCTGGCTGGCGATCACCGGACCCAAGGAGCACGCCAGCAGCTTCATCGAGGGCATCG
GCCTGCTGGCCAATATGCGGTTGTGCCCAAATGTCCCGGCCCAGCATGCCATTCAGGTTGCACTGGGCGGCCATCAGAGC
ATCGAGGACCTGGTGCTGCCCGGCGGCCGGCTGCTCGAGCAGCGCGACATCGCCTGGACCAAGCTCAACGAGATCCCGGG
GGTGTCGTGCGTCAAACCGGCGGGCGCGCTGTATGCGTTTCCCCGGCTAGACCCCGAGGTCTACGACATCGACGACGACG
AGCAACTCGTGCTCGATCTGCTGCTGTCGGAGAAGATCCTGGTCACCCAGGGCACCGGGTTCAACTGGCCCGCACCGGAT
CATCTGCGCCTGGTGACGCTGCCATGGTCCCGCGATCTGGCGGCCGCCATCGAGCGGCTGGGTAACTTCCTGGTCAGTTA
CCGGCAATAG

Upstream 100 bases:

>100_bases
GGCTGCACCGGCCGCGCCGGTGAAAGGGCTGGGCATTGCGCGCGGGGCCCGTCCACCGGGCAAACGCTGATCACGATTTG
GCACCTGACAGCAAATTCCA

Downstream 100 bases:

>100_bases
CAGCCGACGCACGTGATGCCCTGGGGGTGGCAGCGCGGCCGGGCGCCCTTAAGCCGGCGCGGCGGCGTCGAGGGAGCGCC
GCAGGGTCCCGTCATCGGAT

Product: aminotransferase AlaT

Products: NA

Alternate protein names: AspAT; Transaminase A

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDNDGTIVDVTTHQLPWHTASHQRQRAFAQSAKLQDVLYEIRGPVHQHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMR
DIIQALPYAQGYSDSQGILSARRAVVTRYELVPGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTAS
TSLAGGTPVHYLCDETQGWQPDIADLESKITERTKALVVINPNNPTGAVYSCEILTQMVDLARKHQLLLLADEIYDKILY
DDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEHASSFIEGIGLLANMRLCPNVPAQHAIQVALGGHQS
IEDLVLPGGRLLEQRDIAWTKLNEIPGVSCVKPAGALYAFPRLDPEVYDIDDDEQLVLDLLLSEKILVTQGTGFNWPAPD
HLRLVTLPWSRDLAAAIERLGNFLVSYRQ

Sequences:

>Translated_429_residues
MDNDGTIVDVTTHQLPWHTASHQRQRAFAQSAKLQDVLYEIRGPVHQHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMR
DIIQALPYAQGYSDSQGILSARRAVVTRYELVPGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTAS
TSLAGGTPVHYLCDETQGWQPDIADLESKITERTKALVVINPNNPTGAVYSCEILTQMVDLARKHQLLLLADEIYDKILY
DDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEHASSFIEGIGLLANMRLCPNVPAQHAIQVALGGHQS
IEDLVLPGGRLLEQRDIAWTKLNEIPGVSCVKPAGALYAFPRLDPEVYDIDDDEQLVLDLLLSEKILVTQGTGFNWPAPD
HLRLVTLPWSRDLAAAIERLGNFLVSYRQ
>Mature_429_residues
MDNDGTIVDVTTHQLPWHTASHQRQRAFAQSAKLQDVLYEIRGPVHQHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMR
DIIQALPYAQGYSDSQGILSARRAVVTRYELVPGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTAS
TSLAGGTPVHYLCDETQGWQPDIADLESKITERTKALVVINPNNPTGAVYSCEILTQMVDLARKHQLLLLADEIYDKILY
DDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEHASSFIEGIGLLANMRLCPNVPAQHAIQVALGGHQS
IEDLVLPGGRLLEQRDIAWTKLNEIPGVSCVKPAGALYAFPRLDPEVYDIDDDEQLVLDLLLSEKILVTQGTGFNWPAPD
HLRLVTLPWSRDLAAAIERLGNFLVSYRQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI19263340, Length=471, Percent_Identity=25.4777070063694, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI4507369, Length=378, Percent_Identity=28.3068783068783, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI215599424, Length=372, Percent_Identity=27.9569892473118, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI4885351, Length=436, Percent_Identity=26.8348623853211, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI95147551, Length=167, Percent_Identity=36.5269461077844, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI169881279, Length=167, Percent_Identity=36.5269461077844, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI56713254, Length=152, Percent_Identity=33.5526315789474, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI56713256, Length=152, Percent_Identity=33.5526315789474, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI169881281, Length=148, Percent_Identity=35.1351351351351, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI149944424, Length=333, Percent_Identity=25.8258258258258, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1788627, Length=400, Percent_Identity=59.75, Blast_Score=533, Evalue=1e-152,
Organism=Escherichia coli, GI1788722, Length=395, Percent_Identity=26.8354430379747, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786816, Length=302, Percent_Identity=24.1721854304636, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787909, Length=169, Percent_Identity=24.8520710059172, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=378, Percent_Identity=29.3650793650794, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71981209, Length=459, Percent_Identity=24.6187363834423, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=184, Percent_Identity=33.695652173913, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994476, Length=184, Percent_Identity=33.695652173913, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=235, Percent_Identity=30.6382978723404, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71981215, Length=294, Percent_Identity=26.530612244898, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=490, Percent_Identity=25.9183673469388, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=471, Percent_Identity=25.9023354564756, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6322401, Length=237, Percent_Identity=26.1603375527426, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859735, Length=374, Percent_Identity=28.6096256684492, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24641770, Length=466, Percent_Identity=25.7510729613734, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641760, Length=466, Percent_Identity=25.7510729613734, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641768, Length=466, Percent_Identity=25.7510729613734, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641766, Length=466, Percent_Identity=25.7510729613734, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641764, Length=466, Percent_Identity=25.7510729613734, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI45551451, Length=466, Percent_Identity=25.7510729613734, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI28573069, Length=301, Percent_Identity=25.5813953488372, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646114, Length=301, Percent_Identity=25.5813953488372, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573067, Length=301, Percent_Identity=25.5813953488372, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573065, Length=301, Percent_Identity=25.5813953488372, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AAT_MYCBO (P63499)

Other databases:

- EMBL:   BX248335
- RefSeq:   NP_854008.1
- ProteinModelPortal:   P63499
- EnsemblBacteria:   EBMYCT00000014688
- GeneID:   1091217
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0344c
- GeneTree:   EBGT00070000031717
- HOGENOM:   HBG645860
- OMA:   MFPKIDT
- ProtClustDB:   PRK09265
- BioCyc:   MBOV233413:MB0344C-MONOMER
- BRENDA:   2.6.1.1
- GO:   GO:0005737
- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PRINTS:   PR00753

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.1

Molecular weight: Translated: 47351; Mature: 47351

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNDGTIVDVTTHQLPWHTASHQRQRAFAQSAKLQDVLYEIRGPVHQHAARLEAEGHRIL
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEE
KLNIGNPAPFGFEAPDVIMRDIIQALPYAQGYSDSQGILSARRAVVTRYELVPGFPRFDV
EEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTASTSLAGGTPVHYLCDETQGWQ
CCEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCCCCCEEEEECCCCCCC
PDIADLESKITERTKALVVINPNNPTGAVYSCEILTQMVDLARKHQLLLLADEIYDKILY
CCHHHHHHHHHHHHCEEEEECCCCCCCCEEHHHHHHHHHHHHHHCCEEEEHHHHHHHHHH
DDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEHASSFIEGIGLLANMR
CCCCCEEHHHCCCCEEEEEEHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCC
LCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDIAWTKLNEIPGVSCVKPAGALYAF
CCCCCCHHHEEEEEECCCCCHHHHHCCCCHHHHHCCCHHHHHHCCCCCCEECCCCCEEEC
PRLDPEVYDIDDDEQLVLDLLLSEKILVTQGTGFNWPAPDHLRLVTLPWSRDLAAAIERL
CCCCCCEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHH
GNFLVSYRQ
HHHHHHCCC
>Mature Secondary Structure
MDNDGTIVDVTTHQLPWHTASHQRQRAFAQSAKLQDVLYEIRGPVHQHAARLEAEGHRIL
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEE
KLNIGNPAPFGFEAPDVIMRDIIQALPYAQGYSDSQGILSARRAVVTRYELVPGFPRFDV
EEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTASTSLAGGTPVHYLCDETQGWQ
CCEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCCCCCEEEEECCCCCCC
PDIADLESKITERTKALVVINPNNPTGAVYSCEILTQMVDLARKHQLLLLADEIYDKILY
CCHHHHHHHHHHHHCEEEEECCCCCCCCEEHHHHHHHHHHHHHHCCEEEEHHHHHHHHHH
DDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEHASSFIEGIGLLANMR
CCCCCEEHHHCCCCEEEEEEHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCC
LCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDIAWTKLNEIPGVSCVKPAGALYAF
CCCCCCHHHEEEEEECCCCCHHHHHCCCCHHHHHCCCHHHHHHCCCCCCEECCCCCEEEC
PRLDPEVYDIDDDEQLVLDLLLSEKILVTQGTGFNWPAPDHLRLVTLPWSRDLAAAIERL
CCCCCCEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHH
GNFLVSYRQ
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972