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The map label for this gene is 148659988

Identifier: 148659988

GI number: 148659988

Start: 269225

End: 269989

Strand: Reverse

Name: 148659988

Synonym: MRA_0232

Alternate gene names: NA

Gene position: 269989-269225 (Counterclockwise)

Preceding gene: 148659990

Following gene: 148659987

Centisome position: 6.11

GC content: 66.93

Gene sequence:

>765_bases
GTGGCGGTCACCGATGTGTTCGCGCGACGGGCGACACTGCGGCGCTCGCTGCGACTGCTGGCAGACTTCCGCTACGAGCA
GCGCGACCCGGCACGGTTCTATCGCACACTGGCGGCCGACACCGCAGCAATGATCGGCGATCTGTGGCTGGCCACACATA
GCGAGCCGCCAGTTGGCCGTACGCTGCTCGACGTTGGCGGCGGGCCGGGGTATTTCGCGACGGCGTTCTCCGACGCCGGT
GTCGGCTACATCGGCGTCGAGCCGGACCCTGATGAAATGCATGCCGCCGGACCTGCGTTCACCGGCCGGCCCGGCATGTT
CGTCCGGGCGTCAGGCATGGCACTGCCGTTCGCCGACGACTCGGTAGACATCTGCTTGTCCTCCAATGTCGCCGAACACG
TGCCGCGCCCCTGGCAGCTTGGCACCGAGATGCTGCGGGTGACCAAGCCAGGCGGGTTGGTCGTGCTGTCCTACACGGTT
TGGCTGGGGCCATTCGGCGGGCACGAGATGGGCCTCAGCCACTACCTCGGCGGCGCCCGCGCCGCCGCCCGATATGTCCG
CAAACACGGCCATCCGGCAAAGAACAACTATGGGTCGTCGTTGTTTGCCGTGTCCGCCGCCGAGGGTCTGCGCTGGGCTG
CCGGCACCGGAGCCGCGTTAGCCGTATTTCCCCGCTACCACCCCAGATGGGCGTGGTGGCTGACATCCGTCCCGGTGCTG
CGTGAGTTCCTGGTGAGCAATCTGGTATTGGTGCTCACACCCTAA

Upstream 100 bases:

>100_bases
CCGCCCCCCTGGGGGTGCCCGATGTCGCGCCAGCACAGCAGCAACACCGAGCGCAGAGCAGACATTGGTCGATAGCCTAG
CGGGCCGTAGGGTGTGCCAG

Downstream 100 bases:

>100_bases
TAATGGAACACGTTCTCGTTTCGCGTTCGGCTTGGGTAGGGTGACGCCATGACCGCCGGCGACGATGCCGAGCGCAGCGA
TGAGGAGGAGCGGCGCATAT

Product: putative methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MAVTDVFARRATLRRSLRLLADFRYEQRDPARFYRTLAADTAAMIGDLWLATHSEPPVGRTLLDVGGGPGYFATAFSDAG
VGYIGVEPDPDEMHAAGPAFTGRPGMFVRASGMALPFADDSVDICLSSNVAEHVPRPWQLGTEMLRVTKPGGLVVLSYTV
WLGPFGGHEMGLSHYLGGARAAARYVRKHGHPAKNNYGSSLFAVSAAEGLRWAAGTGAALAVFPRYHPRWAWWLTSVPVL
REFLVSNLVLVLTP

Sequences:

>Translated_254_residues
MAVTDVFARRATLRRSLRLLADFRYEQRDPARFYRTLAADTAAMIGDLWLATHSEPPVGRTLLDVGGGPGYFATAFSDAG
VGYIGVEPDPDEMHAAGPAFTGRPGMFVRASGMALPFADDSVDICLSSNVAEHVPRPWQLGTEMLRVTKPGGLVVLSYTV
WLGPFGGHEMGLSHYLGGARAAARYVRKHGHPAKNNYGSSLFAVSAAEGLRWAAGTGAALAVFPRYHPRWAWWLTSVPVL
REFLVSNLVLVLTP
>Mature_253_residues
AVTDVFARRATLRRSLRLLADFRYEQRDPARFYRTLAADTAAMIGDLWLATHSEPPVGRTLLDVGGGPGYFATAFSDAGV
GYIGVEPDPDEMHAAGPAFTGRPGMFVRASGMALPFADDSVDICLSSNVAEHVPRPWQLGTEMLRVTKPGGLVVLSYTVW
LGPFGGHEMGLSHYLGGARAAARYVRKHGHPAKNNYGSSLFAVSAAEGLRWAAGTGAALAVFPRYHPRWAWWLTSVPVLR
EFLVSNLVLVLTP

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y224_MYCTU (P96406)

Other databases:

- EMBL:   BX842572
- EMBL:   AE000516
- PIR:   F70961
- RefSeq:   NP_214738.1
- RefSeq:   NP_334641.1
- ProteinModelPortal:   P96406
- SMR:   P96406
- EnsemblBacteria:   EBMYCT00000002238
- EnsemblBacteria:   EBMYCT00000069015
- GeneID:   886715
- GeneID:   923130
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0234
- KEGG:   mtu:Rv0224c
- TIGR:   MT0234
- TubercuList:   Rv0224c
- GeneTree:   EBGT00050000014604
- HOGENOM:   HBG429288
- OMA:   GHETGLW
- ProtClustDB:   CLSK871773
- GO:   GO:0040007
- InterPro:   IPR013216

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 27511; Mature: 27380

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTDVFARRATLRRSLRLLADFRYEQRDPARFYRTLAADTAAMIGDLWLATHSEPPVGR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCC
TLLDVGGGPGYFATAFSDAGVGYIGVEPDPDEMHAAGPAFTGRPGMFVRASGMALPFADD
EEEECCCCCCEEEEEECCCCCEEECCCCCHHHHHCCCCCCCCCCCEEEEECCEEECCCCC
SVDICLSSNVAEHVPRPWQLGTEMLRVTKPGGLVVLSYTVWLGPFGGHEMGLSHYLGGAR
CEEEEECCCHHHHCCCCHHHHHHHEEEECCCCEEEEEEEEEECCCCCCHHHHHHHHCHHH
AAARYVRKHGHPAKNNYGSSLFAVSAAEGLRWAAGTGAALAVFPRYHPRWAWWLTSVPVL
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEECCCCCEEEECCCCCCCHHHHHHHHHHH
REFLVSNLVLVLTP
HHHHHCCEEEEECC
>Mature Secondary Structure 
AVTDVFARRATLRRSLRLLADFRYEQRDPARFYRTLAADTAAMIGDLWLATHSEPPVGR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCC
TLLDVGGGPGYFATAFSDAGVGYIGVEPDPDEMHAAGPAFTGRPGMFVRASGMALPFADD
EEEECCCCCCEEEEEECCCCCEEECCCCCHHHHHCCCCCCCCCCCEEEEECCEEECCCCC
SVDICLSSNVAEHVPRPWQLGTEMLRVTKPGGLVVLSYTVWLGPFGGHEMGLSHYLGGAR
CEEEEECCCHHHHCCCCHHHHHHHEEEECCCCEEEEEEEEEECCCCCCHHHHHHHHCHHH
AAARYVRKHGHPAKNNYGSSLFAVSAAEGLRWAAGTGAALAVFPRYHPRWAWWLTSVPVL
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEECCCCCEEEECCCCCCCHHHHHHHHHHH
REFLVSNLVLVLTP
HHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036