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The map label for this gene is 148659867

Identifier: 148659867

GI number: 148659867

Start: 123675

End: 125189

Strand: Direct

Name: 148659867

Synonym: MRA_0109

Alternate gene names: NA

Gene position: 123675-125189 (Clockwise)

Preceding gene: 148659865

Following gene: 148659869

Centisome position: 2.8

GC content: 63.83

Gene sequence:

>1515_bases
GTGACGCCCGTCACAACGTTTCCTCTCGTGGACGCGATCCTCGCTGGTCGCGACCGCAACCTTGACGGCGTTATCTTGAT
CGCCGCCCAACACCTGCTGCAAACAACGCACGCCATGCTGCGTTCGCTATTTCGGGTCGGCCTCGATCCGCGCAACGTCG
CGGTGATCGGCAAGTGCTATTCCACTCACCCGGGAGTTGTCGACGCGATGCGGGCCGACGGCATCTATGTCGACGATTGC
AGCGACGCCTACGCACCCCACGAATCATTCGACACCCAGTACACCCGCCACGTAGAACGGTTTTTCGCCGAATCCTGGGC
GCGGCTTACGGCCGGGCGTACGGCTCGTGTCGTGCTCCTCGACGACGGCGGATCGCTGCTAGCCGTCGCCGGCGCCATGC
TCGATGCGAGCGCCGACGTGATCGGAATCGAGCAGACGTCCGCCGGCTACGCCAAAATCGTCGGTTGTGCGCTGGGGTTT
CCCGTCATCAACATCGCCCGCTCGTCGGCAAAGCTTCTATACGAGTCGCCGATCATCGCCGCACGCGTGACACAGACGGC
ATTCGAGCGCACCGCGGGCATCGACTCAAGCGCAGCGATCCTGATCACCGGCGCGGGCGCAATCGGCACTGCCCTGGCCG
ATGTGCTGCGTCCGCTGCATGACCGGGTGGACGTGTACGACACGCGCTCCGGCTGTATGACGCCCATCGATCTTCCGAAT
GCGATCGGCGGCTATGACGTGATCATCGGTGCCACCGGCGCCACCAGTGTGCCCGCCAGCATGCACGAATTGCTGCGCCC
CGGCGTATTGCTGATGTCGGCGTCTTCGTCCGATCGCGAGTTCGATGCCGTCGCGTTGCGTCGGCGCACGACGCCCAATC
CTGACTGCCATGCCGACCTCAGGGTAGCCGACGGCAGTGTCGACGCTACCTTGTTGAATTCGGGCTTCCCGGTCAACTTT
GACGGTTCGCCCATGTGCGGCGATGCGTCGATGGCGCTCACGATGGCGTTGTTGGCGGCCGCGGTGTTGTATGCGTCGGT
CGCGGTCGCCGACGAAATGTCATCCGATCATCCGCATCTCGGGCTGATCGACCAGGGCGACATCGTGGCATCGTTTCTGA
ACATCGACGTCCCGCTCCAAGCTCTCAGCCGGCTACCGTTGCTTTCGATCGATGGGTATCGCCGCCTTCAGGTGCGCTCC
GGCTATACCTTGTTCCGCCAAGGTGAGCGGGCCGACCACTTCTTTGTCATCGAATCCGGCGAGCTTGAGGCGCTCGTCGA
CGGGAAGGTCATCCTTAGACTCGGTGCCGGAGACCACTTCGGCGAGGCGTGTTTGCTCGGTGGCATGCGGCGCATAGCGA
CGGTGCGGGCATGTGAGCCATCGGTCCTGTGGGAGCTCGACGGCAAGGCTTTCGGCGACGCGCTGCATGGGGACGCTGCA
ATGCGTGAGATCGCCTACGGTGTCGCTCGCACCCGGCTCATGCACGCCGGCGCGTCCGAGTCCTTGATGGTGTAA

Upstream 100 bases:

>100_bases
TCGTAAGCAGGCGGTAATCGGTTCCCTATGGCCCGCTGGATGCACTGGCGATGGATTCTTTTGGTCCGATTTCTGCGGTT
GGCGTGCTAGGTTTCCGACT

Downstream 100 bases:

>100_bases
CGGTCTTGCACTCGTGGGCTGTCGGCGGATCACGGGATCGTTATGCCGGTTCTTGCGAGTGACATAGGTTGACATACGTA
TAACCGGTCCCTGCGGTCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MTPVTTFPLVDAILAGRDRNLDGVILIAAQHLLQTTHAMLRSLFRVGLDPRNVAVIGKCYSTHPGVVDAMRADGIYVDDC
SDAYAPHESFDTQYTRHVERFFAESWARLTAGRTARVVLLDDGGSLLAVAGAMLDASADVIGIEQTSAGYAKIVGCALGF
PVINIARSSAKLLYESPIIAARVTQTAFERTAGIDSSAAILITGAGAIGTALADVLRPLHDRVDVYDTRSGCMTPIDLPN
AIGGYDVIIGATGATSVPASMHELLRPGVLLMSASSSDREFDAVALRRRTTPNPDCHADLRVADGSVDATLLNSGFPVNF
DGSPMCGDASMALTMALLAAAVLYASVAVADEMSSDHPHLGLIDQGDIVASFLNIDVPLQALSRLPLLSIDGYRRLQVRS
GYTLFRQGERADHFFVIESGELEALVDGKVILRLGAGDHFGEACLLGGMRRIATVRACEPSVLWELDGKAFGDALHGDAA
MREIAYGVARTRLMHAGASESLMV

Sequences:

>Translated_504_residues
MTPVTTFPLVDAILAGRDRNLDGVILIAAQHLLQTTHAMLRSLFRVGLDPRNVAVIGKCYSTHPGVVDAMRADGIYVDDC
SDAYAPHESFDTQYTRHVERFFAESWARLTAGRTARVVLLDDGGSLLAVAGAMLDASADVIGIEQTSAGYAKIVGCALGF
PVINIARSSAKLLYESPIIAARVTQTAFERTAGIDSSAAILITGAGAIGTALADVLRPLHDRVDVYDTRSGCMTPIDLPN
AIGGYDVIIGATGATSVPASMHELLRPGVLLMSASSSDREFDAVALRRRTTPNPDCHADLRVADGSVDATLLNSGFPVNF
DGSPMCGDASMALTMALLAAAVLYASVAVADEMSSDHPHLGLIDQGDIVASFLNIDVPLQALSRLPLLSIDGYRRLQVRS
GYTLFRQGERADHFFVIESGELEALVDGKVILRLGAGDHFGEACLLGGMRRIATVRACEPSVLWELDGKAFGDALHGDAA
MREIAYGVARTRLMHAGASESLMV
>Mature_503_residues
TPVTTFPLVDAILAGRDRNLDGVILIAAQHLLQTTHAMLRSLFRVGLDPRNVAVIGKCYSTHPGVVDAMRADGIYVDDCS
DAYAPHESFDTQYTRHVERFFAESWARLTAGRTARVVLLDDGGSLLAVAGAMLDASADVIGIEQTSAGYAKIVGCALGFP
VINIARSSAKLLYESPIIAARVTQTAFERTAGIDSSAAILITGAGAIGTALADVLRPLHDRVDVYDTRSGCMTPIDLPNA
IGGYDVIIGATGATSVPASMHELLRPGVLLMSASSSDREFDAVALRRRTTPNPDCHADLRVADGSVDATLLNSGFPVNFD
GSPMCGDASMALTMALLAAAVLYASVAVADEMSSDHPHLGLIDQGDIVASFLNIDVPLQALSRLPLLSIDGYRRLQVRSG
YTLFRQGERADHFFVIESGELEALVDGKVILRLGAGDHFGEACLLGGMRRIATVRACEPSVLWELDGKAFGDALHGDAAM
REIAYGVARTRLMHAGASESLMV

Specific function: Unknown

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y104_MYCTU (Q10898)

Other databases:

- EMBL:   BX842572
- EMBL:   AE000516
- PIR:   H70751
- RefSeq:   NP_214618.1
- RefSeq:   NP_334521.1
- ProteinModelPortal:   Q10898
- SMR:   Q10898
- EnsemblBacteria:   EBMYCT00000002355
- EnsemblBacteria:   EBMYCT00000071075
- GeneID:   886923
- GeneID:   922963
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0113
- KEGG:   mtu:Rv0104
- TIGR:   MT0113
- TubercuList:   Rv0104
- GeneTree:   EBGT00050000014789
- HOGENOM:   HBG565119
- OMA:   LETTHAM
- ProtClustDB:   CLSK871756
- GO:   GO:0005488
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR016040
- InterPro:   IPR014710
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:2.60.120.10
- SMART:   SM00100

Pfam domain/function: PF00027 cNMP_binding; SSF51206 cNMP_binding

EC number: NA

Molecular weight: Translated: 53452; Mature: 53320

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1bc841d4)-; HASH(0x1bdf2cbc)-; HASH(0x1bdd767c)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVTTFPLVDAILAGRDRNLDGVILIAAQHLLQTTHAMLRSLFRVGLDPRNVAVIGKCY
CCCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
STHPGVVDAMRADGIYVDDCSDAYAPHESFDTQYTRHVERFFAESWARLTAGRTARVVLL
CCCCCHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
DDGGSLLAVAGAMLDASADVIGIEQTSAGYAKIVGCALGFPVINIARSSAKLLYESPIIA
ECCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHH
ARVTQTAFERTAGIDSSAAILITGAGAIGTALADVLRPLHDRVDVYDTRSGCMTPIDLPN
HHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCC
AIGGYDVIIGATGATSVPASMHELLRPGVLLMSASSSDREFDAVALRRRTTPNPDCHADL
CCCCEEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEE
RVADGSVDATLLNSGFPVNFDGSPMCGDASMALTMALLAAAVLYASVAVADEMSSDHPHL
EEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
GLIDQGDIVASFLNIDVPLQALSRLPLLSIDGYRRLQVRSGYTLFRQGERADHFFVIESG
EEECCCHHHHHHHCCCCCHHHHHCCCEEECCCCEEEEEECCCCEEECCCCCCEEEEEECC
ELEALVDGKVILRLGAGDHFGEACLLGGMRRIATVRACEPSVLWELDGKAFGDALHGDAA
CEEEEECCEEEEEECCCCCCCHHHHHCCHHHHHHHHCCCCCEEEEECCCHHCCHHCCHHH
MREIAYGVARTRLMHAGASESLMV
HHHHHHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure 
TPVTTFPLVDAILAGRDRNLDGVILIAAQHLLQTTHAMLRSLFRVGLDPRNVAVIGKCY
CCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
STHPGVVDAMRADGIYVDDCSDAYAPHESFDTQYTRHVERFFAESWARLTAGRTARVVLL
CCCCCHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
DDGGSLLAVAGAMLDASADVIGIEQTSAGYAKIVGCALGFPVINIARSSAKLLYESPIIA
ECCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHH
ARVTQTAFERTAGIDSSAAILITGAGAIGTALADVLRPLHDRVDVYDTRSGCMTPIDLPN
HHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCC
AIGGYDVIIGATGATSVPASMHELLRPGVLLMSASSSDREFDAVALRRRTTPNPDCHADL
CCCCEEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEE
RVADGSVDATLLNSGFPVNFDGSPMCGDASMALTMALLAAAVLYASVAVADEMSSDHPHL
EEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
GLIDQGDIVASFLNIDVPLQALSRLPLLSIDGYRRLQVRSGYTLFRQGERADHFFVIESG
EEECCCHHHHHHHCCCCCHHHHHCCCEEECCCCEEEEEECCCCEEECCCCCCEEEEEECC
ELEALVDGKVILRLGAGDHFGEACLLGGMRRIATVRACEPSVLWELDGKAFGDALHGDAA
CEEEEECCEEEEEECCCCCCCHHHHHCCHHHHHHHHCCCCCEEEEECCCHHCCHHCCHHH
MREIAYGVARTRLMHAGASESLMV
HHHHHHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036