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The map label for this gene is moaB [H]

Identifier: 148652034

GI number: 148652034

Start: 259365

End: 259892

Strand: Direct

Name: moaB [H]

Synonym: PsycPRwf_0218

Alternate gene names: 148652034

Gene position: 259365-259892 (Clockwise)

Preceding gene: 148652033

Following gene: 148652035

Centisome position: 8.71

GC content: 48.48

Gene sequence:

>528_bases
ATGTCAAAAGAAAAAGTATTTACTCCGTTAAATGTGGCGGTATTGACCGTCTCTGATAGCCGTACGTTAGAGCAAGATAC
GTCAGGTCAGTATCTGGTGGACTCGCTGCAAGAAGCGGGACACAACCTGGCTGATCGTCAGTTAATCACCGATGATATTT
ACAAAATCCGAGCCGTGATTAGTGGCTGGATTGCTGACCCTGAGGTGCATGCGGTGATGACCACGGGCGGTACGGGGTTT
TATATCCGTGACAGCATGCCTGAAGCGGTCAGCGTGTTATTTGACAAAAAAATCGATGGCTTTGGTGAGATGTTCCGTTT
GATCTCCAAGGATGAGATTGGCATGTCAACGGTACAATCACGTGCTATTGCTGGTATGGCCAATAACACAGTGATTTTCT
GTCTGCCAGGCTCATCAGGCGCTTGCCGTACCGGTTGGACCAAGATTATCAAAGATCAGTTAGACAGCCGCACTGGCCCT
TGTAACTTTGTGCCGCATTTAATGCGCGTTAACCCAGGCCACGATTAG

Upstream 100 bases:

>100_bases
ATGATTGGTGGTTAACAGGATTGGCGGCTAAGCCAAAAGGTACGTTTCAAAGCCATCTGTTTAAATCTTAATTGTTTTCC
CTGTTATTTAAGGCGCTTTT

Downstream 100 bases:

>100_bases
TTATATGACAGACGCCTTGCTGCGCAGACTGGACGCAGAGCCTTTAGCGGGGGTGGTTATCCTCGCCGGCGGCTTATCGA
CGCGTATGGGCTCACCTAAG

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSKEKVFTPLNVAVLTVSDSRTLEQDTSGQYLVDSLQEAGHNLADRQLITDDIYKIRAVISGWIADPEVHAVMTTGGTGF
YIRDSMPEAVSVLFDKKIDGFGEMFRLISKDEIGMSTVQSRAIAGMANNTVIFCLPGSSGACRTGWTKIIKDQLDSRTGP
CNFVPHLMRVNPGHD

Sequences:

>Translated_175_residues
MSKEKVFTPLNVAVLTVSDSRTLEQDTSGQYLVDSLQEAGHNLADRQLITDDIYKIRAVISGWIADPEVHAVMTTGGTGF
YIRDSMPEAVSVLFDKKIDGFGEMFRLISKDEIGMSTVQSRAIAGMANNTVIFCLPGSSGACRTGWTKIIKDQLDSRTGP
CNFVPHLMRVNPGHD
>Mature_174_residues
SKEKVFTPLNVAVLTVSDSRTLEQDTSGQYLVDSLQEAGHNLADRQLITDDIYKIRAVISGWIADPEVHAVMTTGGTGFY
IRDSMPEAVSVLFDKKIDGFGEMFRLISKDEIGMSTVQSRAIAGMANNTVIFCLPGSSGACRTGWTKIIKDQLDSRTGPC
NFVPHLMRVNPGHD

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=134, Percent_Identity=33.5820895522388, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI10880983, Length=134, Percent_Identity=33.5820895522388, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1787000, Length=163, Percent_Identity=55.2147239263804, Blast_Score=200, Evalue=6e-53,
Organism=Drosophila melanogaster, GI17136978, Length=146, Percent_Identity=34.2465753424658, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24638841, Length=146, Percent_Identity=34.2465753424658, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 19154; Mature: 19023

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEKVFTPLNVAVLTVSDSRTLEQDTSGQYLVDSLQEAGHNLADRQLITDDIYKIRAVI
CCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SGWIADPEVHAVMTTGGTGFYIRDSMPEAVSVLFDKKIDGFGEMFRLISKDEIGMSTVQS
HHHCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
RAIAGMANNTVIFCLPGSSGACRTGWTKIIKDQLDSRTGPCNFVPHLMRVNPGHD
HHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHEECCCCCC
>Mature Secondary Structure 
SKEKVFTPLNVAVLTVSDSRTLEQDTSGQYLVDSLQEAGHNLADRQLITDDIYKIRAVI
CCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SGWIADPEVHAVMTTGGTGFYIRDSMPEAVSVLFDKKIDGFGEMFRLISKDEIGMSTVQS
HHHCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
RAIAGMANNTVIFCLPGSSGACRTGWTKIIKDQLDSRTGPCNFVPHLMRVNPGHD
HHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]