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The map label for this gene is torC [H]

Identifier: 148652029

GI number: 148652029

Start: 251656

End: 252891

Strand: Direct

Name: torC [H]

Synonym: PsycPRwf_0213

Alternate gene names: 148652029

Gene position: 251656-252891 (Clockwise)

Preceding gene: 148652021

Following gene: 148652030

Centisome position: 8.45

GC content: 49.03

Gene sequence:

>1236_bases
ATGAACGCAATTAAACGCCTATTTGGTTGGCTGCGTCAGCTTCTATTTAAACCGGCTGCAAAAATTGGGCTTGGTGTATT
AATTATCATCGGCTTCGTAGGCGGGGTATGGTTTTGGGCAGGCTTTAACTCAGCGCTAGAAGCGACAAATAGCGAAGAGT
TCTGTTTGTCTTGTCATACCATGAAAGACAACATGCTGCCTGAGCTACAAAAAACGGTGCATTGGCAAAACCGCACTGGG
GTGCGTGCTGAGTGTCAAGATTGTCACGTGCCACACCAGTTCACCGATAAGATTGCCCGTAAGATGCAGGCCTCGCGTGA
AGTGTTGTCACACGTTATGGGTGATATCGGTACACGCGATAAGTTCTTGGCACACCGCGGGGTATTGGCGCAGCGTGAAT
GGGCTCGGTTTAAGGCGAATAACTCAAAAGAGTGCCGCGCTTGTCACGACTATGACAGCATGGACTTTAGCAAAATGCGC
GTGACCTCACAGATGATTATGCGTAGCGCCGCTGAGCGTGATGCCAGCTGTGTTGACTGTCACAAAGGGATTGCGCACGA
ATTACCAGTTATGGAAGGCATGCACAACCCCGCGTTCGACTCTTTGGTATCTGAGGCGGGCAGCACCAAGATTAATGTGG
GCGAAACTTACTATAACATCGTGCCGCAACCTTTATATTTAGATGCTGAAAAAACCAAGCAAGCGGGCACCATTGAAGTG
GCAGCTCCTGCAAAAGTTATTGCCCACGAAAAAGGCATGACTCAAATTGAGCTGGATATGTGGCGTAAGAACAAGGGCTT
CGGCCGAGTTTGGTACACCCACTTTGGCCTAAACATTGTCGATGCCGTCATTGAAAAAGATCTGTCTCGTGATGAGAGTA
TTGTGAAGGTAAAAGAGTCCAAAGAGGATCCTTTAACCGGTCTTGAATGGCAAAAAGTCAGCGGTACCTTCTGGGTAGAA
GATGGCCTATTAATGAAGAGTCTAGAGCCTGCTTGGGACATCGCCGGACAGACTTATGCAGAGAACTGTAGTGTGTGTCA
CCGTCAACCAAACCCAGCCTCGCATGATGCCAACCAGTGGCCAGGGCTATGGAGTGGTATGGTTGGATTTACCAACCTCG
ACGCAGATACTGGTGGCTTAGTACTCAAATATCTACAGCTGAACTCATCTGACTTTGCGGGTGCCAAAAATGCCCCAGGC
TCACCTGAGAATACGCCTCAGATGGCTCGTCCATAA

Upstream 100 bases:

>100_bases
GCCAATGCGCATTACTGATTATTAAAAGGCATCAAGCACCTAATCAGCGAGCGAGCTATTTACGGATAGCAATTGATGCA
AACAATGGCAAGGAATCATC

Downstream 100 bases:

>100_bases
GGCACCATGCGCATAATAAGACACACAAGAATAGGCAGAATAATAAGGGTTATATTATGAAAAATATCAATCGCAGGGGC
TTTTTAAAATCGCTGGCGGC

Product: trimethylamine-N-oxide reductase c-type cytochrome TorC

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MNAIKRLFGWLRQLLFKPAAKIGLGVLIIIGFVGGVWFWAGFNSALEATNSEEFCLSCHTMKDNMLPELQKTVHWQNRTG
VRAECQDCHVPHQFTDKIARKMQASREVLSHVMGDIGTRDKFLAHRGVLAQREWARFKANNSKECRACHDYDSMDFSKMR
VTSQMIMRSAAERDASCVDCHKGIAHELPVMEGMHNPAFDSLVSEAGSTKINVGETYYNIVPQPLYLDAEKTKQAGTIEV
AAPAKVIAHEKGMTQIELDMWRKNKGFGRVWYTHFGLNIVDAVIEKDLSRDESIVKVKESKEDPLTGLEWQKVSGTFWVE
DGLLMKSLEPAWDIAGQTYAENCSVCHRQPNPASHDANQWPGLWSGMVGFTNLDADTGGLVLKYLQLNSSDFAGAKNAPG
SPENTPQMARP

Sequences:

>Translated_411_residues
MNAIKRLFGWLRQLLFKPAAKIGLGVLIIIGFVGGVWFWAGFNSALEATNSEEFCLSCHTMKDNMLPELQKTVHWQNRTG
VRAECQDCHVPHQFTDKIARKMQASREVLSHVMGDIGTRDKFLAHRGVLAQREWARFKANNSKECRACHDYDSMDFSKMR
VTSQMIMRSAAERDASCVDCHKGIAHELPVMEGMHNPAFDSLVSEAGSTKINVGETYYNIVPQPLYLDAEKTKQAGTIEV
AAPAKVIAHEKGMTQIELDMWRKNKGFGRVWYTHFGLNIVDAVIEKDLSRDESIVKVKESKEDPLTGLEWQKVSGTFWVE
DGLLMKSLEPAWDIAGQTYAENCSVCHRQPNPASHDANQWPGLWSGMVGFTNLDADTGGLVLKYLQLNSSDFAGAKNAPG
SPENTPQMARP
>Mature_411_residues
MNAIKRLFGWLRQLLFKPAAKIGLGVLIIIGFVGGVWFWAGFNSALEATNSEEFCLSCHTMKDNMLPELQKTVHWQNRTG
VRAECQDCHVPHQFTDKIARKMQASREVLSHVMGDIGTRDKFLAHRGVLAQREWARFKANNSKECRACHDYDSMDFSKMR
VTSQMIMRSAAERDASCVDCHKGIAHELPVMEGMHNPAFDSLVSEAGSTKINVGETYYNIVPQPLYLDAEKTKQAGTIEV
AAPAKVIAHEKGMTQIELDMWRKNKGFGRVWYTHFGLNIVDAVIEKDLSRDESIVKVKESKEDPLTGLEWQKVSGTFWVE
DGLLMKSLEPAWDIAGQTYAENCSVCHRQPNPASHDANQWPGLWSGMVGFTNLDADTGGLVLKYLQLNSSDFAGAKNAPG
SPENTPQMARP

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA. Acts by transferring electrons from the membranous menaquinones to TorA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal dom

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1787230, Length=392, Percent_Identity=37.2448979591837, Blast_Score=268, Evalue=4e-73,
Organism=Escherichia coli, GI1788530, Length=196, Percent_Identity=46.9387755102041, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI1788181, Length=375, Percent_Identity=28.8, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 45948; Mature: 45948

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAIKRLFGWLRQLLFKPAAKIGLGVLIIIGFVGGVWFWAGFNSALEATNSEEFCLSCHT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHH
MKDNMLPELQKTVHWQNRTGVRAECQDCHVPHQFTDKIARKMQASREVLSHVMGDIGTRD
HHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
KFLAHRGVLAQREWARFKANNSKECRACHDYDSMDFSKMRVTSQMIMRSAAERDASCVDC
HHHHHHCCHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
HKGIAHELPVMEGMHNPAFDSLVSEAGSTKINVGETYYNIVPQPLYLDAEKTKQAGTIEV
HHHHHHHCHHHHCCCCHHHHHHHHHCCCCEEEECCHHHHCCCCCEEECHHHCCCCCCEEE
AAPAKVIAHEKGMTQIELDMWRKNKGFGRVWYTHFGLNIVDAVIEKDLSRDESIVKVKES
CCCHHHHHHCCCCCEEEHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEECCC
KEDPLTGLEWQKVSGTFWVEDGLLMKSLEPAWDIAGQTYAENCSVCHRQPNPASHDANQW
CCCCCCCCCEEECCCEEEECCCHHHHHCCHHHHHCCCHHHHCCHHHCCCCCCCCCCCCCC
PGLWSGMVGFTNLDADTGGLVLKYLQLNSSDFAGAKNAPGSPENTPQMARP
CCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNAIKRLFGWLRQLLFKPAAKIGLGVLIIIGFVGGVWFWAGFNSALEATNSEEFCLSCHT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHH
MKDNMLPELQKTVHWQNRTGVRAECQDCHVPHQFTDKIARKMQASREVLSHVMGDIGTRD
HHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
KFLAHRGVLAQREWARFKANNSKECRACHDYDSMDFSKMRVTSQMIMRSAAERDASCVDC
HHHHHHCCHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
HKGIAHELPVMEGMHNPAFDSLVSEAGSTKINVGETYYNIVPQPLYLDAEKTKQAGTIEV
HHHHHHHCHHHHCCCCHHHHHHHHHCCCCEEEECCHHHHCCCCCEEECHHHCCCCCCEEE
AAPAKVIAHEKGMTQIELDMWRKNKGFGRVWYTHFGLNIVDAVIEKDLSRDESIVKVKES
CCCHHHHHHCCCCCEEEHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEECCC
KEDPLTGLEWQKVSGTFWVEDGLLMKSLEPAWDIAGQTYAENCSVCHRQPNPASHDANQW
CCCCCCCCCEEECCCEEEECCCHHHHHCCHHHHHCCCHHHHCCHHHCCCCCCCCCCCCCC
PGLWSGMVGFTNLDADTGGLVLKYLQLNSSDFAGAKNAPGSPENTPQMARP
CCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]