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The map label for this gene is dnaA [H]

Identifier: 148651819

GI number: 148651819

Start: 1311

End: 2723

Strand: Direct

Name: dnaA [H]

Synonym: PsycPRwf_0002

Alternate gene names: 148651819

Gene position: 1311-2723 (Clockwise)

Preceding gene: NA

Following gene: 148651820

Centisome position: 0.04

GC content: 45.36

Gene sequence:

>1413_bases
ATGTCAGATAGTTTGTCGTTGTGGGATAGATGTCTTAATGACTTAAGATATCAGCTCAAAGAAAATGAGTTTACGATGTG
GCTGCGTCCACTTTCAGCTCATATCATTGGGGATAAGCTAGAGTTGCTTGCTCCAAACCAGTATTTTGTCTCCCACGTAC
AGCAGCATCATTTTGCCGCAATTGAAGTATTGGCTAAGCAGCATAGCAATGGCGAAATACGTCAAGTTGTGATTCAAGTG
GAAAGTAGCGTGCACTCTGGTGGGCAGACGAAAGCGGGCCACACTACCCTAGCCAGTGCGCAAAATGGCCCTGTGGTGAT
GAGTGCTCAACAAAATCTGCAAACTCAAAATGAAGAGGATGCCGATGCCGCCCAAATGGCGTCAGATAAGTCACTTAGTT
ATATCAATCCCTATTTTACTTTTGAGACCTTTGTCAGTGGTAAGTCTAATATGCTGGCTTACAAAGCCTGTCAGGAGCTT
GGCAAAAAACAATCGCAGAATCGTCATAACCCGTTGTTCTTGTACGGACCTTCTGGTCTCGGTAAGACGCATCTGATGCA
CTCTGTGGCACATCGATACTTGAAAATTGGTAAAACGTTTTACTATTTTTCTTCTGAGAAGTTTATCAATCAGCTGGTCT
ATGCACTACGTAACCAGAAGATTGAAGAGTTCAAACGTAAGATTAAACGGGTGGACTTGTTGATTATTGATGACGTGCAT
GTGTTGGCGGGCAAAAATAAATCCAGCAATGAGTTTTTGTCGTTATTTGCCGATTTTATGGTTGAGGGCAAGCAAGTTAT
CCTAGCTTCAGACCGTCATCCGTCACAGATGACAGAGTTTGATGAACGATTTCGCTCACGTTTTTCATCAGGGCTGGCTG
TGGCGATTGAGCCGCCTGAGATGGAAACACGCATGCAGATTCTGCAGAAAAAAGCTCATCTATCAGGGGTTGATCTTCCC
AAAGAGTGCGCTTTATTTATTGCTCAAAACGTGGTGTCGAATGTCAGACGTTTAGAAGGGGCATTAAACCAAGTGGTGGC
CACAGCCAACTTGACCGGGAATCCCATTGACCTTGACATGGTGCAGTATGCACTAAAAGATGTGATAGCCATTCGCTCGC
AAGCGGTAAGTATGGATAACATACGTAAGGTGGTGGCGGAGTACTATGATGTGTCGGTGAAGGATTTGATGAGTAAAAAA
CGCACCCGTAGCATCGCGCGTCCTCGTCAAATTGCCATGGCCCTGGCTCGGGAGCTAACCAAAGACAGCTTCCCTGATAT
TGGCCAGTCTTTTGGCGGTCGTGATCACACCACAGTCATGCACGCCTGTGATAAGATTGCTCAACTGCGTAGCGAAGATC
CGGTGTTGGATAAAGAATATAAAGCCTTATCTATGACTCTACAGGCGGGATAA

Upstream 100 bases:

>100_bases
TGATTTAGTGTGGTAAAGTACCCCCACGAAATAAGACAGACAGGTTAATTGTTACTGTCTATTTTGCTTTTTTTGTCCGT
TTTATTAGGGTTAATGGGTC

Downstream 100 bases:

>100_bases
GATTACAATCTGGCCTGACTTCAGCCTTATTTAGTTGCTGGGGCAGGGGTGTTTGTGGTGTGTACTTTGTTATTTGGGTA
TACTAACAGGTCACTATTAA

Product: chromosomal replication initiator protein DnaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MSDSLSLWDRCLNDLRYQLKENEFTMWLRPLSAHIIGDKLELLAPNQYFVSHVQQHHFAAIEVLAKQHSNGEIRQVVIQV
ESSVHSGGQTKAGHTTLASAQNGPVVMSAQQNLQTQNEEDADAAQMASDKSLSYINPYFTFETFVSGKSNMLAYKACQEL
GKKQSQNRHNPLFLYGPSGLGKTHLMHSVAHRYLKIGKTFYYFSSEKFINQLVYALRNQKIEEFKRKIKRVDLLIIDDVH
VLAGKNKSSNEFLSLFADFMVEGKQVILASDRHPSQMTEFDERFRSRFSSGLAVAIEPPEMETRMQILQKKAHLSGVDLP
KECALFIAQNVVSNVRRLEGALNQVVATANLTGNPIDLDMVQYALKDVIAIRSQAVSMDNIRKVVAEYYDVSVKDLMSKK
RTRSIARPRQIAMALARELTKDSFPDIGQSFGGRDHTTVMHACDKIAQLRSEDPVLDKEYKALSMTLQAG

Sequences:

>Translated_470_residues
MSDSLSLWDRCLNDLRYQLKENEFTMWLRPLSAHIIGDKLELLAPNQYFVSHVQQHHFAAIEVLAKQHSNGEIRQVVIQV
ESSVHSGGQTKAGHTTLASAQNGPVVMSAQQNLQTQNEEDADAAQMASDKSLSYINPYFTFETFVSGKSNMLAYKACQEL
GKKQSQNRHNPLFLYGPSGLGKTHLMHSVAHRYLKIGKTFYYFSSEKFINQLVYALRNQKIEEFKRKIKRVDLLIIDDVH
VLAGKNKSSNEFLSLFADFMVEGKQVILASDRHPSQMTEFDERFRSRFSSGLAVAIEPPEMETRMQILQKKAHLSGVDLP
KECALFIAQNVVSNVRRLEGALNQVVATANLTGNPIDLDMVQYALKDVIAIRSQAVSMDNIRKVVAEYYDVSVKDLMSKK
RTRSIARPRQIAMALARELTKDSFPDIGQSFGGRDHTTVMHACDKIAQLRSEDPVLDKEYKALSMTLQAG
>Mature_469_residues
SDSLSLWDRCLNDLRYQLKENEFTMWLRPLSAHIIGDKLELLAPNQYFVSHVQQHHFAAIEVLAKQHSNGEIRQVVIQVE
SSVHSGGQTKAGHTTLASAQNGPVVMSAQQNLQTQNEEDADAAQMASDKSLSYINPYFTFETFVSGKSNMLAYKACQELG
KKQSQNRHNPLFLYGPSGLGKTHLMHSVAHRYLKIGKTFYYFSSEKFINQLVYALRNQKIEEFKRKIKRVDLLIIDDVHV
LAGKNKSSNEFLSLFADFMVEGKQVILASDRHPSQMTEFDERFRSRFSSGLAVAIEPPEMETRMQILQKKAHLSGVDLPK
ECALFIAQNVVSNVRRLEGALNQVVATANLTGNPIDLDMVQYALKDVIAIRSQAVSMDNIRKVVAEYYDVSVKDLMSKKR
TRSIARPRQIAMALARELTKDSFPDIGQSFGGRDHTTVMHACDKIAQLRSEDPVLDKEYKALSMTLQAG

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=476, Percent_Identity=43.2773109243698, Blast_Score=390, Evalue=1e-109,
Organism=Escherichia coli, GI226510964, Length=208, Percent_Identity=24.5192307692308, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 53002; Mature: 52871

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSLSLWDRCLNDLRYQLKENEFTMWLRPLSAHIIGDKLELLAPNQYFVSHVQQHHFAA
CCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHH
IEVLAKQHSNGEIRQVVIQVESSVHSGGQTKAGHTTLASAQNGPVVMSAQQNLQTQNEED
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEECHHHCCCCCCCC
ADAAQMASDKSLSYINPYFTFETFVSGKSNMLAYKACQELGKKQSQNRHNPLFLYGPSGL
HHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
GKTHLMHSVAHRYLKIGKTFYYFSSEKFINQLVYALRNQKIEEFKRKIKRVDLLIIDDVH
CHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHCHHHHHHHHHHHHCEEEEECCC
VLAGKNKSSNEFLSLFADFMVEGKQVILASDRHPSQMTEFDERFRSRFSSGLAVAIEPPE
EEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCC
METRMQILQKKAHLSGVDLPKECALFIAQNVVSNVRRLEGALNQVVATANLTGNPIDLDM
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
VQYALKDVIAIRSQAVSMDNIRKVVAEYYDVSVKDLMSKKRTRSIARPRQIAMALARELT
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
KDSFPDIGQSFGGRDHTTVMHACDKIAQLRSEDPVLDKEYKALSMTLQAG
HCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHEEEECC
>Mature Secondary Structure 
SDSLSLWDRCLNDLRYQLKENEFTMWLRPLSAHIIGDKLELLAPNQYFVSHVQQHHFAA
CCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHH
IEVLAKQHSNGEIRQVVIQVESSVHSGGQTKAGHTTLASAQNGPVVMSAQQNLQTQNEED
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEECHHHCCCCCCCC
ADAAQMASDKSLSYINPYFTFETFVSGKSNMLAYKACQELGKKQSQNRHNPLFLYGPSGL
HHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
GKTHLMHSVAHRYLKIGKTFYYFSSEKFINQLVYALRNQKIEEFKRKIKRVDLLIIDDVH
CHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHCHHHHHHHHHHHHCEEEEECCC
VLAGKNKSSNEFLSLFADFMVEGKQVILASDRHPSQMTEFDERFRSRFSSGLAVAIEPPE
EEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCC
METRMQILQKKAHLSGVDLPKECALFIAQNVVSNVRRLEGALNQVVATANLTGNPIDLDM
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
VQYALKDVIAIRSQAVSMDNIRKVVAEYYDVSVKDLMSKKRTRSIARPRQIAMALARELT
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
KDSFPDIGQSFGGRDHTTVMHACDKIAQLRSEDPVLDKEYKALSMTLQAG
HCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA