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The map label for this gene is res [H]

Identifier: 148550835

GI number: 148550835

Start: 308586

End: 309146

Strand: Direct

Name: res [H]

Synonym: Swit_5399

Alternate gene names: 148550835

Gene position: 308586-309146 (Clockwise)

Preceding gene: 148550832

Following gene: NA

Centisome position: 99.47

GC content: 58.82

Gene sequence:

>561_bases
ATGAAGCTCGGCTACGCGCGCGTTTCCACCGAGGATCAGAACTTGGAAATCCAGCGCGGTCGGCTCTCGGAGGCGGGCTG
TGAAATGATGTTCGAAGAGAAAATATCGGGGGCCGCTCGTGGCCGGCCCGAGCTTGAAAAGCTGATGGGTCACCTGCGCA
AAGACGATGTTCTCGTCGTCGCCCGCCTCGATCGTTTGGCGCGATCCACCATCGAACTCCTGCACATCGCGGAACGCATC
AAGGAAAAGCAGGCAGGATTACAATCGCTTGATGAACCTTGGGCCGATACCACGTCCCCGTCTGGCGTGATGATCATGAC
CGTATTCGCTGGGATCGCCCAGTTCGAGCGGACTCTCATATTGAGCCGAACCGAGGAGGGGCGAAAGGCGGCGATGGCGC
GCGGTGTGAGCTTCGGACGCCCAAAGAAAATGCGCCCAGATCAGGCGGAGCTCGCTCGCCAACTCGTTCTCGAGGGTAAG
TCCATTAGCGCCGTCGCAAGGACCTTCAACGTTCACCCGGCCACCATCTATCGCTGTATCGAGCCAAACAGTGCCTTATG
A

Upstream 100 bases:

>100_bases
GACGGCCCATGCCGATAAACAAGGCGAATTTCTTCGCAAAACATATGTGCGAAACAAAATTGTTTTGCAGTAACTTTCGC
ACAATATCTGGAGCAGTCGC

Downstream 100 bases:

>100_bases
CACTTTCCTGTTCCGCTCAGCCGCACGACCCATAGCCTGCTCGACATCGAGCGCGGTTACGCGCCGCACCGCGTCCGCCC
GCGTCCGCTCAGCGGTCGCC

Product: resolvase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKLGYARVSTEDQNLEIQRGRLSEAGCEMMFEEKISGAARGRPELEKLMGHLRKDDVLVVARLDRLARSTIELLHIAERI
KEKQAGLQSLDEPWADTTSPSGVMIMTVFAGIAQFERTLILSRTEEGRKAAMARGVSFGRPKKMRPDQAELARQLVLEGK
SISAVARTFNVHPATIYRCIEPNSAL

Sequences:

>Translated_186_residues
MKLGYARVSTEDQNLEIQRGRLSEAGCEMMFEEKISGAARGRPELEKLMGHLRKDDVLVVARLDRLARSTIELLHIAERI
KEKQAGLQSLDEPWADTTSPSGVMIMTVFAGIAQFERTLILSRTEEGRKAAMARGVSFGRPKKMRPDQAELARQLVLEGK
SISAVARTFNVHPATIYRCIEPNSAL
>Mature_186_residues
MKLGYARVSTEDQNLEIQRGRLSEAGCEMMFEEKISGAARGRPELEKLMGHLRKDDVLVVARLDRLARSTIELLHIAERI
KEKQAGLQSLDEPWADTTSPSGVMIMTVFAGIAQFERTLILSRTEEGRKAAMARGVSFGRPKKMRPDQAELARQLVLEGK
SISAVARTFNVHPATIYRCIEPNSAL

Specific function: A likely role for the res protein would be to stabilize pCP13 by reducing the number of plasmid multimers resulting from homologous recombination [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the site-specific recombinase resolvase family [H]

Homologues:

Organism=Escherichia coli, GI1787404, Length=178, Percent_Identity=41.0112359550562, Blast_Score=129, Evalue=9e-32,
Organism=Escherichia coli, GI1787638, Length=182, Percent_Identity=36.2637362637363, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787827, Length=182, Percent_Identity=36.2637362637363, Blast_Score=107, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR006118
- InterPro:   IPR006119
- InterPro:   IPR006120 [H]

Pfam domain/function: PF02796 HTH_7; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 20736; Mature: 20736

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00397 RECOMBINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGYARVSTEDQNLEIQRGRLSEAGCEMMFEEKISGAARGRPELEKLMGHLRKDDVLVV
CCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHH
ARLDRLARSTIELLHIAERIKEKQAGLQSLDEPWADTTSPSGVMIMTVFAGIAQFERTLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LSRTEEGRKAAMARGVSFGRPKKMRPDQAELARQLVLEGKSISAVARTFNVHPATIYRCI
HHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHEEEC
EPNSAL
CCCCCC
>Mature Secondary Structure
MKLGYARVSTEDQNLEIQRGRLSEAGCEMMFEEKISGAARGRPELEKLMGHLRKDDVLVV
CCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHH
ARLDRLARSTIELLHIAERIKEKQAGLQSLDEPWADTTSPSGVMIMTVFAGIAQFERTLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LSRTEEGRKAAMARGVSFGRPKKMRPDQAELARQLVLEGKSISAVARTFNVHPATIYRCI
HHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHEEEC
EPNSAL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]