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The map label for this gene is htpG [H]

Identifier: 148550787

GI number: 148550787

Start: 257895

End: 259787

Strand: Direct

Name: htpG [H]

Synonym: Swit_5351

Alternate gene names: 148550787

Gene position: 257895-259787 (Clockwise)

Preceding gene: 148550786

Following gene: 148550788

Centisome position: 83.13

GC content: 64.24

Gene sequence:

>1893_bases
ATGAGCACGATTACCGACGCTTCCCCCGACACGCGGTCCTTTGAAGCCGATGTCGCCAAGCTGCTGCACCTCATGGTGCA
CTCCGTTTATTCGGACAAGGATGTCTTCCTTCGCGAACTGGTGTCCAATGCCGCCGACGCCTGCGAAAAGCTGCGCTACG
AAGCGATAGCGGCGCCGGCACTGCTGGGTGACGACCCTCAGCCGCGGATCACGATCACGCTCGATCCCGATGCGCGCCAG
TTGACCATCGAGGATAATGGCATCGGCATGACCCAGGCCGAAATGGCCGAGGCGCTCGGCACGATCGCCCGCTCAGGCAC
CAAAGCCTTCATGGAACAGATCGCCGCCAAGAAGGATGGCGAGGGCGGCCAGCTCATCGGCCAGTTTGGCGTCGGCTTCT
ATTCCGCCTTCATGGTCGCAGACAAGGTCGACGTGTTGTCGCGCCGCGCTGGCGAGGAGGGGGCTGGCCTGTGGACGTCT
GATGGGCTCGGAACCTACGCGATCGGGGATGCTGATCCGGCCGAGGCCCCGGCGCGCGGAACGCGCGTCATTCTTCATCT
CAAGGAAGACGCGGCGGACTATACCCGGCGCTTCAGCGTGGAGCCCAAGATCAAGGCTCAGTCGGGCCATGTCCCAGTGC
CGATCGTCCTCAAGGACAAACCCGATGCGGAGCCGGCGCAGATTGCCGATGGCGCGGCGCTGTGGACGCGGTCCAAGTCC
GAAATCAGCGAGGAAGACTATACCGACTTCTATAGGACCAACGCCGGACAGTTCGACACGCCGGCACTGACGCTGCACTA
TCGCGCCGAGGGCGTGCACGAATATAATGTGCTCGCTTTTGTGCCTGAGATGCGGCCCTTCGACCTGTTCGACCCCGATC
GGGCCGGGCGGATGAAGCTCTATGTTCGCCGGGTGTTCATCACGGGCGAGGCGCAGATCCTGCCCCGCTACCTGCGCTTT
GTGCGCGGACTGGTCGACTCGCAGGACCTGCCGCTCAACGTCTCGCGCGAGATGATCCAGGAGAGCCCGGTTCTGGCCGC
GATCCAGAAGGGGGTTTCGAACCGCGTGTTGAGCGAACTGGAAAAGCTCGCGAACAGCGATGGCGACAAGTATCTCAAGA
TCTGGGAGAATTTTGGGTCGGTCCTGAAGGAGGGTCTCTACGAGGACTATGCCCGGCGCGAGACGCTGCTGGGGCTCGCC
CGCTTCAAGACCAGCACGTCGAACAATGAATGGCGGTCGCTCAAGGACTATGCTGCCGATCTGAAAGAGAACCAGACCGC
GATCTATTATGCGGTGGGTTCCGACATCGAGCGGCTCGCCTCCTCGCCGCAGCTCGAAGGCTTCCGCGCGCGCGGCATCG
AGGTGCTCCTGCTGACCGACCAGATCGACGGTTTCTGGGTGACCGGAGCGCCGGATTTCGAAGGCAAGCCGTTCAAGTCG
GTGACACAGGGCATGTCGGATCTGGGTCTCATCCCCCTCGCCGATGGCGAGCAACCGCCGGCGGAAACGTCGGACGAGGT
CGCCGGCTTCATCGACTTCGTCAAGGCGACGCTGGGCGATGTGGTGTCCGATGTCCGCGCGTCGGAACGGCTGACCGACA
GCCCGGTCTGCCTGGTCGCGCCCGAACACGGCATGGACCGCCAGATGGAGCGGCTCCTGGCGGGCGCGGGGCAGCTTGCG
CAGGTGAGCAAGCCGGTCCTCGAGATCAATCCCCGGCACGCGCTCGTTACCCGGCTCAGCGCGGTAGGCGCAGAGCAGGC
GGATCTGCGCGAGGATGCAGCGCATCTGCTGTTCGACGAGGCCCGCATCGCCGACGGGGAACTGCCGCTCGATCCGCGCG
CCTTTTCTGAACGGCTTGGCCGGGTCCTGCTCCGCGGCAGCGGCCCGATCTGA

Upstream 100 bases:

>100_bases
CTCGGGTCCTGCCCCGCGATCACGCCGGTTCCCCGGGTTGAAAAACCGGGCGGTGCCAACCAGATTTCGCCCGCCATTCC
AAGGAGAGCGAAATATAGCG

Downstream 100 bases:

>100_bases
AGGCCCGGTTGGGGCGTGTCTCAGCCGGCCGCTCATGCCAAGGTAAGATTTACTGCCCGGGTCCGCTTCGCAGTGGGTCC
GGGCCATACCGCATTCTTCG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 630; Mature: 629

Protein sequence:

>630_residues
MSTITDASPDTRSFEADVAKLLHLMVHSVYSDKDVFLRELVSNAADACEKLRYEAIAAPALLGDDPQPRITITLDPDARQ
LTIEDNGIGMTQAEMAEALGTIARSGTKAFMEQIAAKKDGEGGQLIGQFGVGFYSAFMVADKVDVLSRRAGEEGAGLWTS
DGLGTYAIGDADPAEAPARGTRVILHLKEDAADYTRRFSVEPKIKAQSGHVPVPIVLKDKPDAEPAQIADGAALWTRSKS
EISEEDYTDFYRTNAGQFDTPALTLHYRAEGVHEYNVLAFVPEMRPFDLFDPDRAGRMKLYVRRVFITGEAQILPRYLRF
VRGLVDSQDLPLNVSREMIQESPVLAAIQKGVSNRVLSELEKLANSDGDKYLKIWENFGSVLKEGLYEDYARRETLLGLA
RFKTSTSNNEWRSLKDYAADLKENQTAIYYAVGSDIERLASSPQLEGFRARGIEVLLLTDQIDGFWVTGAPDFEGKPFKS
VTQGMSDLGLIPLADGEQPPAETSDEVAGFIDFVKATLGDVVSDVRASERLTDSPVCLVAPEHGMDRQMERLLAGAGQLA
QVSKPVLEINPRHALVTRLSAVGAEQADLREDAAHLLFDEARIADGELPLDPRAFSERLGRVLLRGSGPI

Sequences:

>Translated_630_residues
MSTITDASPDTRSFEADVAKLLHLMVHSVYSDKDVFLRELVSNAADACEKLRYEAIAAPALLGDDPQPRITITLDPDARQ
LTIEDNGIGMTQAEMAEALGTIARSGTKAFMEQIAAKKDGEGGQLIGQFGVGFYSAFMVADKVDVLSRRAGEEGAGLWTS
DGLGTYAIGDADPAEAPARGTRVILHLKEDAADYTRRFSVEPKIKAQSGHVPVPIVLKDKPDAEPAQIADGAALWTRSKS
EISEEDYTDFYRTNAGQFDTPALTLHYRAEGVHEYNVLAFVPEMRPFDLFDPDRAGRMKLYVRRVFITGEAQILPRYLRF
VRGLVDSQDLPLNVSREMIQESPVLAAIQKGVSNRVLSELEKLANSDGDKYLKIWENFGSVLKEGLYEDYARRETLLGLA
RFKTSTSNNEWRSLKDYAADLKENQTAIYYAVGSDIERLASSPQLEGFRARGIEVLLLTDQIDGFWVTGAPDFEGKPFKS
VTQGMSDLGLIPLADGEQPPAETSDEVAGFIDFVKATLGDVVSDVRASERLTDSPVCLVAPEHGMDRQMERLLAGAGQLA
QVSKPVLEINPRHALVTRLSAVGAEQADLREDAAHLLFDEARIADGELPLDPRAFSERLGRVLLRGSGPI
>Mature_629_residues
STITDASPDTRSFEADVAKLLHLMVHSVYSDKDVFLRELVSNAADACEKLRYEAIAAPALLGDDPQPRITITLDPDARQL
TIEDNGIGMTQAEMAEALGTIARSGTKAFMEQIAAKKDGEGGQLIGQFGVGFYSAFMVADKVDVLSRRAGEEGAGLWTSD
GLGTYAIGDADPAEAPARGTRVILHLKEDAADYTRRFSVEPKIKAQSGHVPVPIVLKDKPDAEPAQIADGAALWTRSKSE
ISEEDYTDFYRTNAGQFDTPALTLHYRAEGVHEYNVLAFVPEMRPFDLFDPDRAGRMKLYVRRVFITGEAQILPRYLRFV
RGLVDSQDLPLNVSREMIQESPVLAAIQKGVSNRVLSELEKLANSDGDKYLKIWENFGSVLKEGLYEDYARRETLLGLAR
FKTSTSNNEWRSLKDYAADLKENQTAIYYAVGSDIERLASSPQLEGFRARGIEVLLLTDQIDGFWVTGAPDFEGKPFKSV
TQGMSDLGLIPLADGEQPPAETSDEVAGFIDFVKATLGDVVSDVRASERLTDSPVCLVAPEHGMDRQMERLLAGAGQLAQ
VSKPVLEINPRHALVTRLSAVGAEQADLREDAAHLLFDEARIADGELPLDPRAFSERLGRVLLRGSGPI

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=632, Percent_Identity=33.7025316455696, Blast_Score=344, Evalue=1e-94,
Organism=Homo sapiens, GI154146191, Length=407, Percent_Identity=35.1351351351351, Blast_Score=238, Evalue=2e-62,
Organism=Homo sapiens, GI153792590, Length=407, Percent_Identity=35.3808353808354, Blast_Score=236, Evalue=7e-62,
Organism=Homo sapiens, GI20149594, Length=405, Percent_Identity=34.8148148148148, Blast_Score=234, Evalue=3e-61,
Organism=Homo sapiens, GI4507677, Length=413, Percent_Identity=33.8983050847458, Blast_Score=224, Evalue=2e-58,
Organism=Escherichia coli, GI1786679, Length=627, Percent_Identity=43.859649122807, Blast_Score=498, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17559162, Length=673, Percent_Identity=34.9182763744428, Blast_Score=397, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17542208, Length=672, Percent_Identity=32.4404761904762, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI115535205, Length=656, Percent_Identity=31.25, Blast_Score=281, Evalue=9e-76,
Organism=Caenorhabditis elegans, GI115535167, Length=429, Percent_Identity=34.4988344988345, Blast_Score=233, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6323840, Length=679, Percent_Identity=33.7260677466863, Blast_Score=388, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6325016, Length=683, Percent_Identity=32.796486090776, Blast_Score=379, Evalue=1e-106,
Organism=Drosophila melanogaster, GI17647529, Length=691, Percent_Identity=33.5745296671491, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=32.4522760646109, Blast_Score=338, Evalue=5e-93,
Organism=Drosophila melanogaster, GI24586016, Length=644, Percent_Identity=34.472049689441, Blast_Score=338, Evalue=1e-92,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 69052; Mature: 68920

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTITDASPDTRSFEADVAKLLHLMVHSVYSDKDVFLRELVSNAADACEKLRYEAIAAPA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LLGDDPQPRITITLDPDARQLTIEDNGIGMTQAEMAEALGTIARSGTKAFMEQIAAKKDG
HCCCCCCCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGGQLIGQFGVGFYSAFMVADKVDVLSRRAGEEGAGLWTSDGLGTYAIGDADPAEAPARG
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEECCCCCCCCCCCC
TRVILHLKEDAADYTRRFSVEPKIKAQSGHVPVPIVLKDKPDAEPAQIADGAALWTRSKS
CEEEEEECHHHHHHHHHCCCCCCEECCCCCCCEEEEECCCCCCCHHHHCCCHHHHCCCHH
EISEEDYTDFYRTNAGQFDTPALTLHYRAEGVHEYNVLAFVPEMRPFDLFDPDRAGRMKL
HCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCEEE
YVRRVFITGEAQILPRYLRFVRGLVDSQDLPLNVSREMIQESPVLAAIQKGVSNRVLSEL
EEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHCHHHHHHHHH
EKLANSDGDKYLKIWENFGSVLKEGLYEDYARRETLLGLARFKTSTSNNEWRSLKDYAAD
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LKENQTAIYYAVGSDIERLASSPQLEGFRARGIEVLLLTDQIDGFWVTGAPDFEGKPFKS
HHCCCEEEEEEECCCHHHHHCCCCCCCHHHCCEEEEEEEECCCCEEEECCCCCCCCCHHH
VTQGMSDLGLIPLADGEQPPAETSDEVAGFIDFVKATLGDVVSDVRASERLTDSPVCLVA
HHCCHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
PEHGMDRQMERLLAGAGQLAQVSKPVLEINPRHALVTRLSAVGAEQADLREDAAHLLFDE
CCCCCHHHHHHHHHCCCHHHHHCCCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ARIADGELPLDPRAFSERLGRVLLRGSGPI
HHCCCCCCCCCHHHHHHHHHHEECCCCCCC
>Mature Secondary Structure 
STITDASPDTRSFEADVAKLLHLMVHSVYSDKDVFLRELVSNAADACEKLRYEAIAAPA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LLGDDPQPRITITLDPDARQLTIEDNGIGMTQAEMAEALGTIARSGTKAFMEQIAAKKDG
HCCCCCCCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGGQLIGQFGVGFYSAFMVADKVDVLSRRAGEEGAGLWTSDGLGTYAIGDADPAEAPARG
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEECCCCCCCCCCCC
TRVILHLKEDAADYTRRFSVEPKIKAQSGHVPVPIVLKDKPDAEPAQIADGAALWTRSKS
CEEEEEECHHHHHHHHHCCCCCCEECCCCCCCEEEEECCCCCCCHHHHCCCHHHHCCCHH
EISEEDYTDFYRTNAGQFDTPALTLHYRAEGVHEYNVLAFVPEMRPFDLFDPDRAGRMKL
HCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCEEE
YVRRVFITGEAQILPRYLRFVRGLVDSQDLPLNVSREMIQESPVLAAIQKGVSNRVLSEL
EEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHCHHHHHHHHH
EKLANSDGDKYLKIWENFGSVLKEGLYEDYARRETLLGLARFKTSTSNNEWRSLKDYAAD
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LKENQTAIYYAVGSDIERLASSPQLEGFRARGIEVLLLTDQIDGFWVTGAPDFEGKPFKS
HHCCCEEEEEEECCCHHHHHCCCCCCCHHHCCEEEEEEEECCCCEEEECCCCCCCCCHHH
VTQGMSDLGLIPLADGEQPPAETSDEVAGFIDFVKATLGDVVSDVRASERLTDSPVCLVA
HHCCHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
PEHGMDRQMERLLAGAGQLAQVSKPVLEINPRHALVTRLSAVGAEQADLREDAAHLLFDE
CCCCCHHHHHHHHHCCCHHHHHCCCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ARIADGELPLDPRAFSERLGRVLLRGSGPI
HHCCCCCCCCCHHHHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA