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The map label for this gene is qheDH [H]

Identifier: 148550575

GI number: 148550575

Start: 27643

End: 29772

Strand: Reverse

Name: qheDH [H]

Synonym: Swit_5136

Alternate gene names: 148550575

Gene position: 29772-27643 (Counterclockwise)

Preceding gene: 148550576

Following gene: 148550574

Centisome position: 9.6

GC content: 60.19

Gene sequence:

>2130_bases
ATGGCCCTTGTGGGGGCGGGCTTCCTCTTGCTGGGTACGACACTGAGTGGTTGCTCGCGGTCGAACGAAGCGAGCAACCG
GGCACCCGTCGATACCTCGAAAATCGCCGGGAAAATTAACGGTGACTTTATTGTCAAGAACGCTGCGACTTCCGAGGAAT
GGCCCAGCTACGGCCTCGACTATTCGGAAACGCGCTTCAGCAAGCTGTCCCAGATATCCACTGACAATGTCGCCCGACTG
GGTTTGGCCTGGACCTATGATCTGGGCTCGACCCGCGGCGTAGAGGCAACGCCGCTTGTTGTGGACGGGATCATGTACGT
GACAGCATCCTGGAGCGTCGTGCATGCAATCAATGTACGGACGGGGAAGCAGTTGTGGACGTTCGATCCGCAAGTGCCGC
GCAGCGCGGGCGGCAAGGGGTGCTGTGACGTCGTGAACCGGGGCGTGGCCGTCTATGAGGGAAAAGTCTTCGTCGGAGCC
TTCGATGGTCGTCTCATCGCGCTTGATGCGGCGTCCGGCGCCAAATTGTGGGAAGAGGACACCAGACTATCGCCGGACTC
GCCAGCCACCATCACCGGCGCGCCGCGTGTGTACAAGGGCAAGGTCATCATTGGTAACGGTGGCGCGGAGCTGGGGTTGC
GTGGCTATATCACCGCCTATGATGCGTCGTCGGGCAAGAAGCTCTGGCGCTGGTTCACGGTCCCGGGAGATCCATCGAAG
CCGTTTGAGAACAAGGCGATGGAAGCCGCCGCCAAGACCTGGGACCCCAGCGGACGCTATTGGGAGGCGGGCGGTGGCGG
CACCGTCTGGAACAGCATGGCGTTCGATCCGCAGCTCAATCTCATGTATATCGGCGTCGGAAACGGGGCGCCTTGGTCGC
GCAATCGCCGCAGTCCCAAGGGCGGCGACAATCTCTATCTCGGATCGATCGTCGCGCTCAATCCTGATACCGGCGAATAT
GTCTGGCACTATCAGGAGACGCCGGGGGACAACTGGGATTACACGTCGACGCAGGATATGATCCTGGCCGACATGACGGT
CGACGGCGCGCCGCGCAAAGTGATCCTGCATGCGCCCAAGAACGGCTTCTTCTTCGTCATCGATCGGACAAACGGCAAAT
TCATCTCCGCGAAGAATTTCGTGCCGGTGAACTGGGCCTCGGGCTATGACAAGGCGGGCAGGCCTATCGAATTGCCCGGC
GTCCGCTCGGCCACGCCCTATGAGATCATTCCCGGTCCTTTTGGCGGGCACAACTGGCATTCCATGTCGTTCAATCCGGC
TTTGGGGCTGGCGTTCATTCCCGCGCAGCATGTGCCGCTTTCGCTGGCGGACGATCCGAAATGGAAATATCGCTCCAACA
TTCCAGGCCAGCCCATGAGCGGCATCGGTTGGAACACAGGCAGTTTGCTGGGAGGCGCGGCGACGAAGGCCAAACCCTTC
GGTCGCCTGATCGCATGGGACCCGGTGCGCCAGAAGCAAGTCTGGAGTCAGGAACAAGTTTCGCCGTGGAATGGTGGCAC
GCTGACCACAGCGGGGAATCTGGTGTTCCAAGGAACCGCAGATGGGCATTTCGTAGCCTATGATGCGCGCAACGGCCATA
AAATGTGGGAGTCGCCGGTAGGCAGTGGCGTCATCGCGGCTCCGATCACCTACCAGATCGATGGCAAGCAGTATGTCTCG
ATTGCGGTGGGTTGGGGCGGTGTTTTCGGTGAGTCCCAGCGCGCTACCGACCGCAGTTCGCCTGGTACGGTCTACACCTT
CGTCATCGGCGGCAAGGCGCCGTTGCCGCAGTTCGGAAAATATGAGCAGGGGGAACTGCTCTCGGGCGTGCCCTATGACA
AGAAGGACGTCGCTCCTGGAGGCGCACTCTACGTCAGCAACTGTCTGTTCTGCCATGGCGTTCCTGGCGTCGACAAGGGA
GGCAATTTGCCCAACCTGGGTTATGCGCCCCGCGAGGCGATCGCCAATCTTGAAGCGTTCGTTTTCGAAGGTGCGATGGC
CGAGCAGGGTATGCCCGATTTCAAGGGCAAGCTTACCGCAGAGGACGTCAAGAAGCTCAAGGCGTTCATTCAAGGCACTG
CAGATTCTGTGCGCGGACAACCTGCCGCGAGCGCAAAACCGAAAAAATAG

Upstream 100 bases:

>100_bases
GAACCGCCTCAATTTGCGTCTTCTGAAGGTCTTCTAAGTATTTGAGAGAAAGAACAAAGACATGTCGATCATCTTTTTCG
GGCGGGGAAAGCCGGGGCGA

Downstream 100 bases:

>100_bases
GCTCGCTTAGAGAGGATGACCGGCGGTTTCGGCGCCCGCCGCCGGTCATCCGATCCTTTGTGAAAAGGCGGCGACAAACG
CTTGCGCCGGTCAGGACTGA

Product: Pyrrolo-quinoline quinone

Products: NA

Alternate protein names: QH-EDH1; Quinohaemoprotein ethanol dehydrogenase type I [H]

Number of amino acids: Translated: 709; Mature: 708

Protein sequence:

>709_residues
MALVGAGFLLLGTTLSGCSRSNEASNRAPVDTSKIAGKINGDFIVKNAATSEEWPSYGLDYSETRFSKLSQISTDNVARL
GLAWTYDLGSTRGVEATPLVVDGIMYVTASWSVVHAINVRTGKQLWTFDPQVPRSAGGKGCCDVVNRGVAVYEGKVFVGA
FDGRLIALDAASGAKLWEEDTRLSPDSPATITGAPRVYKGKVIIGNGGAELGLRGYITAYDASSGKKLWRWFTVPGDPSK
PFENKAMEAAAKTWDPSGRYWEAGGGGTVWNSMAFDPQLNLMYIGVGNGAPWSRNRRSPKGGDNLYLGSIVALNPDTGEY
VWHYQETPGDNWDYTSTQDMILADMTVDGAPRKVILHAPKNGFFFVIDRTNGKFISAKNFVPVNWASGYDKAGRPIELPG
VRSATPYEIIPGPFGGHNWHSMSFNPALGLAFIPAQHVPLSLADDPKWKYRSNIPGQPMSGIGWNTGSLLGGAATKAKPF
GRLIAWDPVRQKQVWSQEQVSPWNGGTLTTAGNLVFQGTADGHFVAYDARNGHKMWESPVGSGVIAAPITYQIDGKQYVS
IAVGWGGVFGESQRATDRSSPGTVYTFVIGGKAPLPQFGKYEQGELLSGVPYDKKDVAPGGALYVSNCLFCHGVPGVDKG
GNLPNLGYAPREAIANLEAFVFEGAMAEQGMPDFKGKLTAEDVKKLKAFIQGTADSVRGQPAASAKPKK

Sequences:

>Translated_709_residues
MALVGAGFLLLGTTLSGCSRSNEASNRAPVDTSKIAGKINGDFIVKNAATSEEWPSYGLDYSETRFSKLSQISTDNVARL
GLAWTYDLGSTRGVEATPLVVDGIMYVTASWSVVHAINVRTGKQLWTFDPQVPRSAGGKGCCDVVNRGVAVYEGKVFVGA
FDGRLIALDAASGAKLWEEDTRLSPDSPATITGAPRVYKGKVIIGNGGAELGLRGYITAYDASSGKKLWRWFTVPGDPSK
PFENKAMEAAAKTWDPSGRYWEAGGGGTVWNSMAFDPQLNLMYIGVGNGAPWSRNRRSPKGGDNLYLGSIVALNPDTGEY
VWHYQETPGDNWDYTSTQDMILADMTVDGAPRKVILHAPKNGFFFVIDRTNGKFISAKNFVPVNWASGYDKAGRPIELPG
VRSATPYEIIPGPFGGHNWHSMSFNPALGLAFIPAQHVPLSLADDPKWKYRSNIPGQPMSGIGWNTGSLLGGAATKAKPF
GRLIAWDPVRQKQVWSQEQVSPWNGGTLTTAGNLVFQGTADGHFVAYDARNGHKMWESPVGSGVIAAPITYQIDGKQYVS
IAVGWGGVFGESQRATDRSSPGTVYTFVIGGKAPLPQFGKYEQGELLSGVPYDKKDVAPGGALYVSNCLFCHGVPGVDKG
GNLPNLGYAPREAIANLEAFVFEGAMAEQGMPDFKGKLTAEDVKKLKAFIQGTADSVRGQPAASAKPKK
>Mature_708_residues
ALVGAGFLLLGTTLSGCSRSNEASNRAPVDTSKIAGKINGDFIVKNAATSEEWPSYGLDYSETRFSKLSQISTDNVARLG
LAWTYDLGSTRGVEATPLVVDGIMYVTASWSVVHAINVRTGKQLWTFDPQVPRSAGGKGCCDVVNRGVAVYEGKVFVGAF
DGRLIALDAASGAKLWEEDTRLSPDSPATITGAPRVYKGKVIIGNGGAELGLRGYITAYDASSGKKLWRWFTVPGDPSKP
FENKAMEAAAKTWDPSGRYWEAGGGGTVWNSMAFDPQLNLMYIGVGNGAPWSRNRRSPKGGDNLYLGSIVALNPDTGEYV
WHYQETPGDNWDYTSTQDMILADMTVDGAPRKVILHAPKNGFFFVIDRTNGKFISAKNFVPVNWASGYDKAGRPIELPGV
RSATPYEIIPGPFGGHNWHSMSFNPALGLAFIPAQHVPLSLADDPKWKYRSNIPGQPMSGIGWNTGSLLGGAATKAKPFG
RLIAWDPVRQKQVWSQEQVSPWNGGTLTTAGNLVFQGTADGHFVAYDARNGHKMWESPVGSGVIAAPITYQIDGKQYVSI
AVGWGGVFGESQRATDRSSPGTVYTFVIGGKAPLPQFGKYEQGELLSGVPYDKKDVAPGGALYVSNCLFCHGVPGVDKGG
NLPNLGYAPREAIANLEAFVFEGAMAEQGMPDFKGKLTAEDVKKLKAFIQGTADSVRGQPAASAKPKK

Specific function: Catalyzes the dye-linked oxidation of primary alcohols to the corresponding aldehydes and the (subsequent) oxidation of the aldehydes to carboxylic acids [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=667, Percent_Identity=26.5367316341829, Blast_Score=170, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009056
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.98.1 [H]

Molecular weight: Translated: 75947; Mature: 75816

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00364 BACTERIAL_PQQ_2 ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVGAGFLLLGTTLSGCSRSNEASNRAPVDTSKIAGKINGDFIVKNAATSEEWPSYGLD
CEEEECCCEEECCHHHCCCCCCCCCCCCCCCHHHHCEECCCCEEEECCCCCCCCCCCCCC
YSETRFSKLSQISTDNVARLGLAWTYDLGSTRGVEATPLVVDGIMYVTASWSVVHAINVR
CCHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCEEECCEEEEEECCEEEEEEEEC
TGKQLWTFDPQVPRSAGGKGCCDVVNRGVAVYEGKVFVGAFDGRLIALDAASGAKLWEED
CCCEEEEECCCCCCCCCCCCHHHHHHCCEEEEECEEEEEEECCEEEEEECCCCCCHHHHH
TRLSPDSPATITGAPRVYKGKVIIGNGGAELGLRGYITAYDASSGKKLWRWFTVPGDPSK
CCCCCCCCEEEECCCCEEECEEEEECCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCC
PFENKAMEAAAKTWDPSGRYWEAGGGGTVWNSMAFDPQLNLMYIGVGNGAPWSRNRRSPK
CHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCCC
GGDNLYLGSIVALNPDTGEYVWHYQETPGDNWDYTSTQDMILADMTVDGAPRKVILHAPK
CCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCC
NGFFFVIDRTNGKFISAKNFVPVNWASGYDKAGRPIELPGVRSATPYEIIPGPFGGHNWH
CCEEEEEECCCCCEEECCCEEEECCCCCCCCCCCEEECCCCCCCCCCEEECCCCCCCCCC
SMSFNPALGLAFIPAQHVPLSLADDPKWKYRSNIPGQPMSGIGWNTGSLLGGAATKAKPF
CEECCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GRLIAWDPVRQKQVWSQEQVSPWNGGTLTTAGNLVFQGTADGHFVAYDARNGHKMWESPV
CCEEEECCCHHHHHCCHHCCCCCCCCEEEECCCEEEEECCCCEEEEEECCCCCHHHCCCC
GSGVIAAPITYQIDGKQYVSIAVGWGGVFGESQRATDRSSPGTVYTFVIGGKAPLPQFGK
CCCEEEEEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCC
YEQGELLSGVPYDKKDVAPGGALYVSNCLFCHGVPGVDKGGNLPNLGYAPREAIANLEAF
CCCCCCCCCCCCCHHHCCCCCEEEEECEEEECCCCCCCCCCCCCCCCCCHHHHHHCCHHE
VFEGAMAEQGMPDFKGKLTAEDVKKLKAFIQGTADSVRGQPAASAKPKK
EECCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ALVGAGFLLLGTTLSGCSRSNEASNRAPVDTSKIAGKINGDFIVKNAATSEEWPSYGLD
EEEECCCEEECCHHHCCCCCCCCCCCCCCCHHHHCEECCCCEEEECCCCCCCCCCCCCC
YSETRFSKLSQISTDNVARLGLAWTYDLGSTRGVEATPLVVDGIMYVTASWSVVHAINVR
CCHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCEEECCEEEEEECCEEEEEEEEC
TGKQLWTFDPQVPRSAGGKGCCDVVNRGVAVYEGKVFVGAFDGRLIALDAASGAKLWEED
CCCEEEEECCCCCCCCCCCCHHHHHHCCEEEEECEEEEEEECCEEEEEECCCCCCHHHHH
TRLSPDSPATITGAPRVYKGKVIIGNGGAELGLRGYITAYDASSGKKLWRWFTVPGDPSK
CCCCCCCCEEEECCCCEEECEEEEECCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCC
PFENKAMEAAAKTWDPSGRYWEAGGGGTVWNSMAFDPQLNLMYIGVGNGAPWSRNRRSPK
CHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCCC
GGDNLYLGSIVALNPDTGEYVWHYQETPGDNWDYTSTQDMILADMTVDGAPRKVILHAPK
CCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCC
NGFFFVIDRTNGKFISAKNFVPVNWASGYDKAGRPIELPGVRSATPYEIIPGPFGGHNWH
CCEEEEEECCCCCEEECCCEEEECCCCCCCCCCCEEECCCCCCCCCCEEECCCCCCCCCC
SMSFNPALGLAFIPAQHVPLSLADDPKWKYRSNIPGQPMSGIGWNTGSLLGGAATKAKPF
CEECCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GRLIAWDPVRQKQVWSQEQVSPWNGGTLTTAGNLVFQGTADGHFVAYDARNGHKMWESPV
CCEEEECCCHHHHHCCHHCCCCCCCCEEEECCCEEEEECCCCEEEEEECCCCCHHHCCCC
GSGVIAAPITYQIDGKQYVSIAVGWGGVFGESQRATDRSSPGTVYTFVIGGKAPLPQFGK
CCCEEEEEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCC
YEQGELLSGVPYDKKDVAPGGALYVSNCLFCHGVPGVDKGGNLPNLGYAPREAIANLEAF
CCCCCCCCCCCCCHHHCCCCCEEEEECEEEECCCCCCCCCCCCCCCCCCHHHHHHCCHHE
VFEGAMAEQGMPDFKGKLTAEDVKKLKAFIQGTADSVRGQPAASAKPKK
EECCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8654419; 7601151; 3521592; 11679760; 11714714 [H]