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The map label for this gene is nagA [H]

Identifier: 148380793

GI number: 148380793

Start: 3008254

End: 3009390

Strand: Reverse

Name: nagA [H]

Synonym: CBO2834

Alternate gene names: 148380793

Gene position: 3009390-3008254 (Counterclockwise)

Preceding gene: 148380794

Following gene: 148380792

Centisome position: 77.42

GC content: 30.69

Gene sequence:

>1137_bases
ATGAGGGCTATAGTCAATGGAAAGATTATAATAGGTAATGAAATATTAGAAAATAAAGTCTTGTTATTTGAAAAAAGGAT
AGTTGATATATTAGATAGAAAGAATATTTATTTAAGTAAAGATTACCAGATTATTGATGCTAAAGGACTATATGTTTCTC
CAGGGTTTATAGACGTCCATATACACGGTTCAGGTGGAAAAGATGTTATGGATGGAGAGCTAGAGTCTATAAGAGTTATA
AGCAATACTATAACTAAAAGAGGTGTGACCTCATTTTTACCAACTACTATGACTATGGCTAAAGAACATATATACAAGGC
CTTAGATGTTATAAAACAGGCAATGAACATGGATTTAGGTGGTGCCAAGGTTTTAGGAGCACACTTAGAAGGTCCTTTTA
TTAATCCAAAATATAAAGGGGCTCAAAAGGAGGACTTTATAAAGAATCCAAGCTTTGATTTTATTAAAGGTTATGAGAAT
GTAATAAAAATAATTACTTTAGCCCCAGAGAAAGATGAGAACTTTGAGTTTTTAAAGGATATTAAGAAAAATACAGATAT
AGTTTTATCTATAGGACATTCAGATGCAACCTATGAGCAGGCTATGGCTGCTATAGATAATGGAATAAGTCGTGCTACAC
ATACTTTTAATGCTATGACTCCTTTAAATCATAGAAAACCGGGAATAATAGGTGCTATTATGAATACTGATATATCTTGC
GAACTTATAGCGGATAATATTCATGTTCATAAGGGAGCTGTTAATATTCTTACTAAAATTAAAGGCAAAGATAAGATTAT
TTTAATTACAGATTCAATGAGAGCCGGATGTATGAACAATGGTGTGTGGGAACTAGGAGGACAGAAAGTTATTGTAAAAA
ATGGTTCTGCTAGATTAGAGGATAATACTTTAGCGGGAAGTATTTTGACTTTAGATAATGCGGTTAAAAATATGAAAAAT
AATATAGAAGCTTCTCTATGTGAAGTTATATCTATGGTAACAGTTAATCCTGCAAAAGATATAAATATATATGACAGAAA
AGGAAGTATTGAAAAAGGAAAAGATGCTGATATTGTCATTTTTGATAAAGATATTAATATTAGTATGACAATTGTTGATG
GAAATATTGTGACTTAG

Upstream 100 bases:

>100_bases
CTAATAAAATGGATAATGTTAAAGATATAAGTAATAAGCTAAAAGAGCAAGTCTATTATCATTTAAAAAGCTAATATTTT
TAGATATGGGGTGATTAAAT

Downstream 100 bases:

>100_bases
ATTATTAGACACAATTAGTTATTGATTTAATAAAAGAGAAATTTAAATTTTAATGAGGTGTGTTTTTATGAGAATTATAG
TAGTGGATAATTATGAAGAA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MRAIVNGKIIIGNEILENKVLLFEKRIVDILDRKNIYLSKDYQIIDAKGLYVSPGFIDVHIHGSGGKDVMDGELESIRVI
SNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMDLGGAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFDFIKGYEN
VIKIITLAPEKDENFEFLKDIKKNTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
ELIADNIHVHKGAVNILTKIKGKDKIILITDSMRAGCMNNGVWELGGQKVIVKNGSARLEDNTLAGSILTLDNAVKNMKN
NIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVIFDKDINISMTIVDGNIVT

Sequences:

>Translated_378_residues
MRAIVNGKIIIGNEILENKVLLFEKRIVDILDRKNIYLSKDYQIIDAKGLYVSPGFIDVHIHGSGGKDVMDGELESIRVI
SNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMDLGGAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFDFIKGYEN
VIKIITLAPEKDENFEFLKDIKKNTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
ELIADNIHVHKGAVNILTKIKGKDKIILITDSMRAGCMNNGVWELGGQKVIVKNGSARLEDNTLAGSILTLDNAVKNMKN
NIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVIFDKDINISMTIVDGNIVT
>Mature_378_residues
MRAIVNGKIIIGNEILENKVLLFEKRIVDILDRKNIYLSKDYQIIDAKGLYVSPGFIDVHIHGSGGKDVMDGELESIRVI
SNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMDLGGAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFDFIKGYEN
VIKIITLAPEKDENFEFLKDIKKNTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
ELIADNIHVHKGAVNILTKIKGKDKIILITDSMRAGCMNNGVWELGGQKVIVKNGSARLEDNTLAGSILTLDNAVKNMKN
NIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVIFDKDINISMTIVDGNIVT

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=414, Percent_Identity=28.5024154589372, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI224922791, Length=417, Percent_Identity=28.537170263789, Blast_Score=161, Evalue=1e-39,
Organism=Escherichia coli, GI1786892, Length=389, Percent_Identity=33.1619537275064, Blast_Score=199, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17553768, Length=375, Percent_Identity=32, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI19920392, Length=393, Percent_Identity=31.0432569974555, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI281361140, Length=407, Percent_Identity=30.7125307125307, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41599; Mature: 41599

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIVNGKIIIGNEILENKVLLFEKRIVDILDRKNIYLSKDYQIIDAKGLYVSPGFIDVH
CCEEECCEEEECCHHHCCCHHHHHHHHHHHHCCCCEEEECCEEEEECCCEEECCCEEEEE
IHGSGGKDVMDGELESIRVISNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMDLG
EECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFDFIKGYENVIKIITLAPEKDENFEFLKD
CCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHEEEEEEECCCCCCCHHHHHH
IKKNTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
HHCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHEEECCCCCCCCCCCEEEEEECCCCEE
ELIADNIHVHKGAVNILTKIKGKDKIILITDSMRAGCMNNGVWELGGQKVIVKNGSARLE
EEEECCEEEECCHHHHHHEECCCCEEEEEECCCCCCCCCCCEEEECCCEEEEECCCCEEC
DNTLAGSILTLDNAVKNMKNNIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVI
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEE
FDKDINISMTIVDGNIVT
EECCCEEEEEEECCEECC
>Mature Secondary Structure
MRAIVNGKIIIGNEILENKVLLFEKRIVDILDRKNIYLSKDYQIIDAKGLYVSPGFIDVH
CCEEECCEEEECCHHHCCCHHHHHHHHHHHHCCCCEEEECCEEEEECCCEEECCCEEEEE
IHGSGGKDVMDGELESIRVISNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMDLG
EECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFDFIKGYENVIKIITLAPEKDENFEFLKD
CCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHEEEEEEECCCCCCCHHHHHH
IKKNTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
HHCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHEEECCCCCCCCCCCEEEEEECCCCEE
ELIADNIHVHKGAVNILTKIKGKDKIILITDSMRAGCMNNGVWELGGQKVIVKNGSARLE
EEEECCEEEECCHHHHHHEECCCCEEEEEECCCCCCCCCCCEEEECCCEEEEECCCCEEC
DNTLAGSILTLDNAVKNMKNNIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVI
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEE
FDKDINISMTIVDGNIVT
EECCCEEEEEEECCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]