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The map label for this gene is rmlC [H]

Identifier: 148380673

GI number: 148380673

Start: 2864365

End: 2864898

Strand: Reverse

Name: rmlC [H]

Synonym: CBO2715

Alternate gene names: 148380673

Gene position: 2864898-2864365 (Counterclockwise)

Preceding gene: 148380674

Following gene: 148380672

Centisome position: 73.71

GC content: 32.21

Gene sequence:

>534_bases
TTGATTTTTAAAGAAACTAAATTTAAAGGAGTATATATTTTAGAAATTGAACCTATAGAAGATGAAAGAGGTTTTTTTGC
ACGAACATGGTGCGAAGAAGAATTTAAAGTGTATGGGTTAAATTCAAACTTAGTCCAGTGTAATATTTCTTTTAATAAAA
GAAGAGGAACACTAAGAGGTATGCATTATCAGATTCCACCCTATGAAGAAGCAAAACTTGTTAGGTGTACAAAAGGTTCA
ATATATGATGTGATTATAGATTTAAGACCGAACTCTAAAACTTTTAAACAATGGACAGCAATAGAACTTACAGATGAAAA
CAGAAAAATGCTTTATATTCCAGAGGGATTTGCACACGGATTTCAAACCCTAGAGGATGATACAGAAGTATTTTATCAAA
TGTCACAATTTTATCATCCTGAATGTGCTAGGGGAATTAGGTGGGATGATTTAACCTTTAGCGTAGATTGGCCGGTACGG
GGGGATGTAATTATTTCTTATAAGGATAAAAATTGGGGAGATTTTATAGTATGA

Upstream 100 bases:

>100_bases
GCCATGGAATATTAAAGAAGAAGTAATAGAACAAATAAAATACATTAGAGAATGGAACGGTAATTTTATAACATTTATCC
CTCAAATTGAGGTGTTTTAG

Downstream 100 bases:

>100_bases
AAAAAGTATTGGTAACAGGAGCTAGTGGATTTATAGGATATAAAACTTTGAATTTCTTAATAAACAAAGGGTATGAAGTA
CATGCATTAACAACAAGAGG

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MIFKETKFKGVYILEIEPIEDERGFFARTWCEEEFKVYGLNSNLVQCNISFNKRRGTLRGMHYQIPPYEEAKLVRCTKGS
IYDVIIDLRPNSKTFKQWTAIELTDENRKMLYIPEGFAHGFQTLEDDTEVFYQMSQFYHPECARGIRWDDLTFSVDWPVR
GDVIISYKDKNWGDFIV

Sequences:

>Translated_177_residues
MIFKETKFKGVYILEIEPIEDERGFFARTWCEEEFKVYGLNSNLVQCNISFNKRRGTLRGMHYQIPPYEEAKLVRCTKGS
IYDVIIDLRPNSKTFKQWTAIELTDENRKMLYIPEGFAHGFQTLEDDTEVFYQMSQFYHPECARGIRWDDLTFSVDWPVR
GDVIISYKDKNWGDFIV
>Mature_177_residues
MIFKETKFKGVYILEIEPIEDERGFFARTWCEEEFKVYGLNSNLVQCNISFNKRRGTLRGMHYQIPPYEEAKLVRCTKGS
IYDVIIDLRPNSKTFKQWTAIELTDENRKMLYIPEGFAHGFQTLEDDTEVFYQMSQFYHPECARGIRWDDLTFSVDWPVR
GDVIISYKDKNWGDFIV

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=166, Percent_Identity=40.9638554216867, Blast_Score=140, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17550412, Length=169, Percent_Identity=37.8698224852071, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21054; Mature: 21054

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFKETKFKGVYILEIEPIEDERGFFARTWCEEEFKVYGLNSNLVQCNISFNKRRGTLRG
CCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCEEEEECCCCEEEEEEEECCCCCCCCC
MHYQIPPYEEAKLVRCTKGSIYDVIIDLRPNSKTFKQWTAIELTDENRKMLYIPEGFAHG
EEEECCCCCCCEEEEECCCCEEEEEEEECCCCCCCCEEEEEEEECCCCEEEEEECHHHHH
FQTLEDDTEVFYQMSQFYHPECARGIRWDDLTFSVDWPVRGDVIISYKDKNWGDFIV
HHCCCCHHHHHHHHHHHCCHHHHCCCEECCEEEEECCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MIFKETKFKGVYILEIEPIEDERGFFARTWCEEEFKVYGLNSNLVQCNISFNKRRGTLRG
CCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCEEEEECCCCEEEEEEEECCCCCCCCC
MHYQIPPYEEAKLVRCTKGSIYDVIIDLRPNSKTFKQWTAIELTDENRKMLYIPEGFAHG
EEEECCCCCCCEEEEECCCCEEEEEEEECCCCCCCCEEEEEEEECCCCEEEEEECHHHHH
FQTLEDDTEVFYQMSQFYHPECARGIRWDDLTFSVDWPVRGDVIISYKDKNWGDFIV
HHCCCCHHHHHHHHHHHCCHHHHCCCEECCEEEEECCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463; 10827167 [H]