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The map label for this gene is 148380670

Identifier: 148380670

GI number: 148380670

Start: 2861510

End: 2862286

Strand: Reverse

Name: 148380670

Synonym: CBO2712

Alternate gene names: NA

Gene position: 2862286-2861510 (Counterclockwise)

Preceding gene: 148380671

Following gene: 148380669

Centisome position: 73.64

GC content: 29.21

Gene sequence:

>777_bases
TTGAAAATATTAATAGATACTGATAATAATACGTGTATTGTGGAGGAAAACCAAAAAAAAGAAGAGCTTAGTTTATATTC
AAAAGAAGCCTTTGAAATATTATCTAAAGAGTGGGTTAAAGTTGGTTGGAATGAAAAATATACGTATACCTTTAGTTGGT
TTGGAAGACCTATAATTCAGATGCCAGAAGATATGATTAGAATTCAAGAATTAATATATAAATTGAAACCAGATGTTATA
GTTGAAACAGGAGTAGCTCATGGAGGATCTTTGATATACTATGCAAGTATTTGTAGAGCTATAGGGAAAGGAAGAGTAGT
GGGTGTAGATATTGAGATAAGACCACACAATAGGAATTCAATAGAAGAACATGAACTATATCCATTGATTACTTTAATAG
AAGGAAGTTCTGTAGAAGAGTCTACATTAGAAAAGGTTAAAAATTGTATAAATCATGGAGAAAAAGTATTAGTAATACTT
GATTCTTGTCATACAAGAGATCATGTATATAATGAACTTAAAATGTATTCAGAGCTAGTATCTAAAGAATTTTATATAGT
TGTACAAGATGGAATAATGGAAGATTTGTATGATGTTCCAAGAGGACAAAAAAGTTGGAAAGAAGATAATCCAGTACAAT
CAGTATGCGATTTTCTTAAAGAAAATGATGAATTTGTTTTAGAGACACCAAAGAGGATTTTTAATGAAAGTAGCTTAAAG
CAAAATATTACGCATTGGCCTAGTGCATGGTTAAAAAGAATAAAAAATGGATTTTAA

Upstream 100 bases:

>100_bases
AAAATATTATTGTTATGAATAAAAATTATTATAATGAAATAAATGAGGTATTAAATAAGGAAAATATAAAGGTAAATTTA
ATTTCGGGGGAGGATTTGAA

Downstream 100 bases:

>100_bases
TAAAAGTTGAGGAGTATATAAATGTTTAATAATATTTATTTTGAAATATCAGGTAAATGTAATGCAAGGTGTCATTGGTG
TCAAACTGGGTTTAAGAATA

Product: hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKILIDTDNNTCIVEENQKKEELSLYSKEAFEILSKEWVKVGWNEKYTYTFSWFGRPIIQMPEDMIRIQELIYKLKPDVI
VETGVAHGGSLIYYASICRAIGKGRVVGVDIEIRPHNRNSIEEHELYPLITLIEGSSVEESTLEKVKNCINHGEKVLVIL
DSCHTRDHVYNELKMYSELVSKEFYIVVQDGIMEDLYDVPRGQKSWKEDNPVQSVCDFLKENDEFVLETPKRIFNESSLK
QNITHWPSAWLKRIKNGF

Sequences:

>Translated_258_residues
MKILIDTDNNTCIVEENQKKEELSLYSKEAFEILSKEWVKVGWNEKYTYTFSWFGRPIIQMPEDMIRIQELIYKLKPDVI
VETGVAHGGSLIYYASICRAIGKGRVVGVDIEIRPHNRNSIEEHELYPLITLIEGSSVEESTLEKVKNCINHGEKVLVIL
DSCHTRDHVYNELKMYSELVSKEFYIVVQDGIMEDLYDVPRGQKSWKEDNPVQSVCDFLKENDEFVLETPKRIFNESSLK
QNITHWPSAWLKRIKNGF
>Mature_258_residues
MKILIDTDNNTCIVEENQKKEELSLYSKEAFEILSKEWVKVGWNEKYTYTFSWFGRPIIQMPEDMIRIQELIYKLKPDVI
VETGVAHGGSLIYYASICRAIGKGRVVGVDIEIRPHNRNSIEEHELYPLITLIEGSSVEESTLEKVKNCINHGEKVLVIL
DSCHTRDHVYNELKMYSELVSKEFYIVVQDGIMEDLYDVPRGQKSWKEDNPVQSVCDFLKENDEFVLETPKRIFNESSLK
QNITHWPSAWLKRIKNGF

Specific function: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD) [H]

COG id: COG3510

COG function: function code V; Cephalosporin hydroxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rhamnosyl O-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007072 [H]

Pfam domain/function: PF04989 CmcI [H]

EC number: NA

Molecular weight: Translated: 30080; Mature: 30080

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIDTDNNTCIVEENQKKEELSLYSKEAFEILSKEWVKVGWNEKYTYTFSWFGRPIIQ
CEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHH
MPEDMIRIQELIYKLKPDVIVETGVAHGGSLIYYASICRAIGKGRVVGVDIEIRPHNRNS
CCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
IEEHELYPLITLIEGSSVEESTLEKVKNCINHGEKVLVILDSCHTRDHVYNELKMYSELV
CCHHHHEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
SKEFYIVVQDGIMEDLYDVPRGQKSWKEDNPVQSVCDFLKENDEFVLETPKRIFNESSLK
CCCEEEEECCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHHCHHHHH
QNITHWPSAWLKRIKNGF
HHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MKILIDTDNNTCIVEENQKKEELSLYSKEAFEILSKEWVKVGWNEKYTYTFSWFGRPIIQ
CEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHH
MPEDMIRIQELIYKLKPDVIVETGVAHGGSLIYYASICRAIGKGRVVGVDIEIRPHNRNS
CCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
IEEHELYPLITLIEGSSVEESTLEKVKNCINHGEKVLVILDSCHTRDHVYNELKMYSELV
CCHHHHEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
SKEFYIVVQDGIMEDLYDVPRGQKSWKEDNPVQSVCDFLKENDEFVLETPKRIFNESSLK
CCCEEEEECCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHHCHHHHH
QNITHWPSAWLKRIKNGF
HHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]