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The map label for this gene is kfoC [H]

Identifier: 148380660

GI number: 148380660

Start: 2848530

End: 2849708

Strand: Reverse

Name: kfoC [H]

Synonym: CBO2702

Alternate gene names: 148380660

Gene position: 2849708-2848530 (Counterclockwise)

Preceding gene: 148380661

Following gene: 148380659

Centisome position: 73.32

GC content: 25.53

Gene sequence:

>1179_bases
ATGGAGTCGAATTTATCAGTCGCAATACCTTGTTATAATTGTAAAAAATACATAAAGAAGACTATAAAAACTTTATTAAA
ACAAACTATATTACCAAAAGAAATAATTTTAGTTAATGATAATAGTTCAGATGATACTATTAAAGTACTGGAAGAAATTC
AAAATAGCAACAAAGAAATAGTAAGAGTTTTTAATTTAACAAAAAATAAAGGACCTTCGTTTGCCAGAAATTATGCCGTA
GACAAATCAAAGGGAGACTATATATTATTTATGGACTCAGATGATTTAGCTTCACCATATTTAATAGAAAAGTCTTTAAC
AAAGCTTAAGAGTATGAATGGAAAAAGCCATGATAAATGGATATTATCTTATACTTCTTATATTCAAATAGATGAAAATG
ATAATATTATAAGTGATATAATAAAAGGTATACAAGTAGAAACAGAAGAAATATTAGGATATGAATTTTTAAGGAACTAT
ATTATATCTACATCAGGTGTTATCCTTAAAAAAAATTATTTTTATGAAGCAGGAAAGTTTAATGAGAGATTAAGTTATTC
GGAGGATTGGGATTTATGGATCAAGGTGGCAGCATTGGGTGGATTTTCTTATCTGAATGAACCATTAGTAAAAGTTAGAA
GGAGAGAAAATAGCCTATCTTCCAATTTAAAGAATATGAAAGATGGAGAAAAAACTGTTTTAAACCAATATGATTTAGAG
TTTATAGAGGAAGCAGTTAATAAAAGAAAAGTGCCAAGCTATATAAATACCTGTGATTTTGTATCTATGCTATTTAGATT
AAATTATTGGGAGGAAGGCTTTGAAAAATTAAAGTGTTTATCAAAAAGCTTTGACTATTACAATATTTATTTTTTGCTAG
GATTATATTATATTAAAAATCAGAATCTAAATTTAGCTTTAGAGAATTTTAATAAAACTATAAATTTAAAACAAAATCAT
GGAGCAGCATTAAATAATTTAGGAGCTATATATTGTTTGTTAGGACAAATAGATCAAGGAAAGCGGTTATTAATTAAAGC
TTTAGAAATATTCCCAAACTATCTAGATGCTATGCATAACTTGGATTTAGTAATTAATAAGAGTAATGTAACGTATAACA
ATATAAATTTTACATGGAGGGAACTAAGAAATACTTTGATAAATTATAAAAATAAGTAA

Upstream 100 bases:

>100_bases
TCAGGATATGTTTTCTTGGGAAGAACAAGAGAAAAAATTGATTGATTTTTATAAAAAAATAACAAATGTATGATATGCAT
ATATGAAAGGATATTAAAAT

Downstream 100 bases:

>100_bases
AGTTTAGGTGATATTTGTGTATGATATAATAATTTTTGGAACAGGAAGTACTTCAAATTTTGTAACTGGATTATTAAATG
ATAATGTAGAAATATTAGCT

Product: glycosyl transferase

Products: NA

Alternate protein names: CS; Chondroitin polymerase; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase; UDP-GalNAc transferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase; UDP-GlcUA transferase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MESNLSVAIPCYNCKKYIKKTIKTLLKQTILPKEIILVNDNSSDDTIKVLEEIQNSNKEIVRVFNLTKNKGPSFARNYAV
DKSKGDYILFMDSDDLASPYLIEKSLTKLKSMNGKSHDKWILSYTSYIQIDENDNIISDIIKGIQVETEEILGYEFLRNY
IISTSGVILKKNYFYEAGKFNERLSYSEDWDLWIKVAALGGFSYLNEPLVKVRRRENSLSSNLKNMKDGEKTVLNQYDLE
FIEEAVNKRKVPSYINTCDFVSMLFRLNYWEEGFEKLKCLSKSFDYYNIYFLLGLYYIKNQNLNLALENFNKTINLKQNH
GAALNNLGAIYCLLGQIDQGKRLLIKALEIFPNYLDAMHNLDLVINKSNVTYNNINFTWRELRNTLINYKNK

Sequences:

>Translated_392_residues
MESNLSVAIPCYNCKKYIKKTIKTLLKQTILPKEIILVNDNSSDDTIKVLEEIQNSNKEIVRVFNLTKNKGPSFARNYAV
DKSKGDYILFMDSDDLASPYLIEKSLTKLKSMNGKSHDKWILSYTSYIQIDENDNIISDIIKGIQVETEEILGYEFLRNY
IISTSGVILKKNYFYEAGKFNERLSYSEDWDLWIKVAALGGFSYLNEPLVKVRRRENSLSSNLKNMKDGEKTVLNQYDLE
FIEEAVNKRKVPSYINTCDFVSMLFRLNYWEEGFEKLKCLSKSFDYYNIYFLLGLYYIKNQNLNLALENFNKTINLKQNH
GAALNNLGAIYCLLGQIDQGKRLLIKALEIFPNYLDAMHNLDLVINKSNVTYNNINFTWRELRNTLINYKNK
>Mature_392_residues
MESNLSVAIPCYNCKKYIKKTIKTLLKQTILPKEIILVNDNSSDDTIKVLEEIQNSNKEIVRVFNLTKNKGPSFARNYAV
DKSKGDYILFMDSDDLASPYLIEKSLTKLKSMNGKSHDKWILSYTSYIQIDENDNIISDIIKGIQVETEEILGYEFLRNY
IISTSGVILKKNYFYEAGKFNERLSYSEDWDLWIKVAALGGFSYLNEPLVKVRRRENSLSSNLKNMKDGEKTVLNQYDLE
FIEEAVNKRKVPSYINTCDFVSMLFRLNYWEEGFEKLKCLSKSFDYYNIYFLLGLYYIKNQNLNLALENFNKTINLKQNH
GAALNNLGAIYCLLGQIDQGKRLLIKALEIFPNYLDAMHNLDLVINKSNVTYNNINFTWRELRNTLINYKNK

Specific function: Catalyzes the polymerization of chondroitin, a polysaccharide composed of a repeating disaccharide of N- acetylgalactosamine (GalNAc) and glucuronic acid (GlcUA) units. Each unit has the composition in beta-(1->4)-GlcUA-beta-(1->3)- GalNAc [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. CS/HAS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787259, Length=198, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790044, Length=103, Percent_Identity=33.9805825242718, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI212640903, Length=136, Percent_Identity=34.5588235294118, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.4.1.175; =2.4.1.226 [H]

Molecular weight: Translated: 45666; Mature: 45666

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESNLSVAIPCYNCKKYIKKTIKTLLKQTILPKEIILVNDNSSDDTIKVLEEIQNSNKEI
CCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCHHE
VRVFNLTKNKGPSFARNYAVDKSKGDYILFMDSDDLASPYLIEKSLTKLKSMNGKSHDKW
EEEECCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCE
ILSYTSYIQIDENDNIISDIIKGIQVETEEILGYEFLRNYIISTSGVILKKNYFYEAGKF
EEEEEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCEECCCCC
NERLSYSEDWDLWIKVAALGGFSYLNEPLVKVRRRENSLSSNLKNMKDGEKTVLNQYDLE
CCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FIEEAVNKRKVPSYINTCDFVSMLFRLNYWEEGFEKLKCLSKSFDYYNIYFLLGLYYIKN
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
QNLNLALENFNKTINLKQNHGAALNNLGAIYCLLGQIDQGKRLLIKALEIFPNYLDAMHN
CCCEEEEECCCCEEEEECCCCCHHHHCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCC
LDLVINKSNVTYNNINFTWRELRNTLINYKNK
CEEEEECCCCEEECCCEEHHHHHHHHHCCCCC
>Mature Secondary Structure
MESNLSVAIPCYNCKKYIKKTIKTLLKQTILPKEIILVNDNSSDDTIKVLEEIQNSNKEI
CCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCHHE
VRVFNLTKNKGPSFARNYAVDKSKGDYILFMDSDDLASPYLIEKSLTKLKSMNGKSHDKW
EEEECCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCE
ILSYTSYIQIDENDNIISDIIKGIQVETEEILGYEFLRNYIISTSGVILKKNYFYEAGKF
EEEEEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCEECCCCC
NERLSYSEDWDLWIKVAALGGFSYLNEPLVKVRRRENSLSSNLKNMKDGEKTVLNQYDLE
CCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FIEEAVNKRKVPSYINTCDFVSMLFRLNYWEEGFEKLKCLSKSFDYYNIYFLLGLYYIKN
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
QNLNLALENFNKTINLKQNHGAALNNLGAIYCLLGQIDQGKRLLIKALEIFPNYLDAMHN
CCCEEEEECCCCEEEEECCCCCHHHHCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCC
LDLVINKSNVTYNNINFTWRELRNTLINYKNK
CEEEEECCCCEEECCCEEHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11943778 [H]