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The map label for this gene is cat [H]

Identifier: 148379515

GI number: 148379515

Start: 1681706

End: 1682341

Strand: Reverse

Name: cat [H]

Synonym: CBO1547

Alternate gene names: 148379515

Gene position: 1682341-1681706 (Counterclockwise)

Preceding gene: 148379517

Following gene: 148379513

Centisome position: 43.28

GC content: 27.36

Gene sequence:

>636_bases
ATGAAATTTATAGATATAGAAAACTGGAAAAGAAAGAATCACTATAATTATTTTAAGCAACTTGATTACCCACATTTTAA
TATTTGTGGAAATCTAGATATTACAAATTTTTATAGGTATATAAAAAAAAATAAACTACCATTTTTTGCATCGGTTTTAT
ATGCTTCTACAAAAACAGCCAATGATATAAGAGAATTTAGATTTAGGATAAGAGAAGATAGGTTAATTGAACATGAAATT
GTAAGTCCTTCTTTTACCGTAATGACTAAAGAAGAAGTGTTTAGCTTTTGTACAGTAAATTTTATAGATAGTTATAACGA
TTTTAAATCTAATGCATTAAAGGAAATTGGAAAAACAAAAAATAATATAACTATAAAGGATGAACCAGGCCGTGATGACT
TATTGTATATAACTAGTATTCCTTGGATTTCATTTACAAATATAACTCACCCAATTCAGATGACCCCCGTTGATAGTATC
CCCAGAATATCTTGGGGTAAATATTTTGAAGAAAGTGGGAAAGTTAAATTACCACTATCTGTACAGGTACATCATGCCTT
GGTTGATGGTATTCATGTAGGAAAATTTTTTAATAATATTCAAGAAATTTTGGATAATCCCATAAAGTATCTATAA

Upstream 100 bases:

>100_bases
AATTTCTGTTTTAAGTATGACATATGTCATATCCCTTTACAACTTTTTCATGATAAATTAAGTTTAATATTTTAATTTTT
CTATGGAAAGTGGTGTAAAT

Downstream 100 bases:

>100_bases
TTTAAAACTTCAACTATTATTTTTATTAGTTTACTTAATTATTTTCTTCTTAAATCATATATAAAACCTCTTATACTATA
ACTTTAAATAAAATAATTAT

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: CAT [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MKFIDIENWKRKNHYNYFKQLDYPHFNICGNLDITNFYRYIKKNKLPFFASVLYASTKTANDIREFRFRIREDRLIEHEI
VSPSFTVMTKEEVFSFCTVNFIDSYNDFKSNALKEIGKTKNNITIKDEPGRDDLLYITSIPWISFTNITHPIQMTPVDSI
PRISWGKYFEESGKVKLPLSVQVHHALVDGIHVGKFFNNIQEILDNPIKYL

Sequences:

>Translated_211_residues
MKFIDIENWKRKNHYNYFKQLDYPHFNICGNLDITNFYRYIKKNKLPFFASVLYASTKTANDIREFRFRIREDRLIEHEI
VSPSFTVMTKEEVFSFCTVNFIDSYNDFKSNALKEIGKTKNNITIKDEPGRDDLLYITSIPWISFTNITHPIQMTPVDSI
PRISWGKYFEESGKVKLPLSVQVHHALVDGIHVGKFFNNIQEILDNPIKYL
>Mature_211_residues
MKFIDIENWKRKNHYNYFKQLDYPHFNICGNLDITNFYRYIKKNKLPFFASVLYASTKTANDIREFRFRIREDRLIEHEI
VSPSFTVMTKEEVFSFCTVNFIDSYNDFKSNALKEIGKTKNNITIKDEPGRDDLLYITSIPWISFTNITHPIQMTPVDSI
PRISWGKYFEESGKVKLPLSVQVHHALVDGIHVGKFFNNIQEILDNPIKYL

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG4845

COG function: function code V; Chloramphenicol O-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloramphenicol acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023213
- InterPro:   IPR018372
- InterPro:   IPR001707
- ProDom:   PD002660 [H]

Pfam domain/function: PF00302 CAT [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 24958; Mature: 24958

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDIENWKRKNHYNYFKQLDYPHFNICGNLDITNFYRYIKKNKLPFFASVLYASTKTA
CCEECCCCCCCCCHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCHHHHHHHHCCCCH
NDIREFRFRIREDRLIEHEIVSPSFTVMTKEEVFSFCTVNFIDSYNDFKSNALKEIGKTK
HHHHHHHHHHHHCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
NNITIKDEPGRDDLLYITSIPWISFTNITHPIQMTPVDSIPRISWGKYFEESGKVKLPLS
CCEEEECCCCCCCEEEEEECCCEEECCCCCCEEECCCCCCCCCCCHHHHHCCCCEEEEEE
VQVHHALVDGIHVGKFFNNIQEILDNPIKYL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHCC
>Mature Secondary Structure
MKFIDIENWKRKNHYNYFKQLDYPHFNICGNLDITNFYRYIKKNKLPFFASVLYASTKTA
CCEECCCCCCCCCHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCHHHHHHHHCCCCH
NDIREFRFRIREDRLIEHEIVSPSFTVMTKEEVFSFCTVNFIDSYNDFKSNALKEIGKTK
HHHHHHHHHHHHCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
NNITIKDEPGRDDLLYITSIPWISFTNITHPIQMTPVDSIPRISWGKYFEESGKVKLPLS
CCEEEECCCCCCCEEEEEECCCEEECCCCCCEEECCCCCCCCCCCHHHHHCCCCEEEEEE
VQVHHALVDGIHVGKFFNNIQEILDNPIKYL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1650008 [H]