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The map label for this gene is fucA [H]

Identifier: 148379252

GI number: 148379252

Start: 1385993

End: 1386640

Strand: Direct

Name: fucA [H]

Synonym: CBO1270

Alternate gene names: 148379252

Gene position: 1385993-1386640 (Clockwise)

Preceding gene: 148379251

Following gene: 148379253

Centisome position: 35.66

GC content: 30.56

Gene sequence:

>648_bases
TTGAATAATGAAACGTATTTAAGGTTACAAATTGTAGAGGTAGGAAAAAGACTTCAACAAAGATTTTTTGTAGCTTCAAA
TGATGGAAATATAAGTGCTAAACTTGATGAAAATACTATATTGATTACGCCTACAGGGGTTAATAAAGGAGAAGTAACCC
CAGATCAAATAATAAAAGTAGATAGAGAAGGAAATGTTATAGAAGGTCATATGAAGGTTACATCTGAAATAAAAATGCAT
TTAGCTGTTTATAATATGAGAGAAGATGTAAAAGCTATAGTTCATGCCCATCCACCAGCATCCACAGCTTTTTCAGTATC
AAAAGAAAAACTAGATGATCCTGTTATTCTTCCAGAAGCAGTTTTTTCATTAGGGAAAATAGGATATTGTGAATATGGAA
CTCCTTCTACTGATGAGGTTCCAAAAGCTATAGAAAAAGAAATTCCATATAGTGATGTACTTTTATTATCTAACCATGGA
GCTCTTACAGTAGGTACAGATGTAATGCAGGCTTATTACAGAATGGAAAATTTAGAAATGGTTTCAAAGGTAACTATTTA
TTCAAAAATGATAGGAAATATAAAAACTTTAAATGAACTACAAGTTGAGAAATTAAATAAAGTAAAAGAAGAAAAAGGTT
GGGGGTAA

Upstream 100 bases:

>100_bases
ATAAAAAAGTCCTTTTCAGATGTTCAAGTATTACATGAAATAAATAATTTGGGGATTTTATCCCCAAATTTATTAATCAC
TTAGTAAAGAGGGTGACAAT

Downstream 100 bases:

>100_bases
ATTATAGTTACCACCCATAGAGCTTTTTAATAATTAGGTAAATATGCCTGTAATAGAACCATTATGTTTAAATTTTGTAA
AAAGTGGTGTCATGTACAAG

Product: AraD/FucA subfamily aldolase

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MNNETYLRLQIVEVGKRLQQRFFVASNDGNISAKLDENTILITPTGVNKGEVTPDQIIKVDREGNVIEGHMKVTSEIKMH
LAVYNMREDVKAIVHAHPPASTAFSVSKEKLDDPVILPEAVFSLGKIGYCEYGTPSTDEVPKAIEKEIPYSDVLLLSNHG
ALTVGTDVMQAYYRMENLEMVSKVTIYSKMIGNIKTLNELQVEKLNKVKEEKGWG

Sequences:

>Translated_215_residues
MNNETYLRLQIVEVGKRLQQRFFVASNDGNISAKLDENTILITPTGVNKGEVTPDQIIKVDREGNVIEGHMKVTSEIKMH
LAVYNMREDVKAIVHAHPPASTAFSVSKEKLDDPVILPEAVFSLGKIGYCEYGTPSTDEVPKAIEKEIPYSDVLLLSNHG
ALTVGTDVMQAYYRMENLEMVSKVTIYSKMIGNIKTLNELQVEKLNKVKEEKGWG
>Mature_215_residues
MNNETYLRLQIVEVGKRLQQRFFVASNDGNISAKLDENTILITPTGVNKGEVTPDQIIKVDREGNVIEGHMKVTSEIKMH
LAVYNMREDVKAIVHAHPPASTAFSVSKEKLDDPVILPEAVFSLGKIGYCEYGTPSTDEVPKAIEKEIPYSDVLLLSNHG
ALTVGTDVMQAYYRMENLEMVSKVTIYSKMIGNIKTLNELQVEKLNKVKEEKGWG

Specific function: Catalyzes the reversible aldol cleavage of L-fuculose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde [H]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Homo sapiens, GI29826325, Length=157, Percent_Identity=35.031847133758, Blast_Score=81, Evalue=5e-16,
Organism=Homo sapiens, GI29826323, Length=157, Percent_Identity=35.031847133758, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI29826321, Length=157, Percent_Identity=35.031847133758, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI29826319, Length=157, Percent_Identity=35.031847133758, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI89276787, Length=210, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI9257190, Length=210, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI297307160, Length=210, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI297307158, Length=210, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI9257192, Length=210, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=8e-14,
Organism=Escherichia coli, GI1789094, Length=185, Percent_Identity=29.1891891891892, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789164, Length=186, Percent_Identity=25.2688172043011, Blast_Score=62, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533218, Length=193, Percent_Identity=27.4611398963731, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115533216, Length=193, Percent_Identity=27.4611398963731, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 24024; Mature: 24024

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNETYLRLQIVEVGKRLQQRFFVASNDGNISAKLDENTILITPTGVNKGEVTPDQIIKV
CCCCEEEEEEHHHHHHHHHHHEEEECCCCCEEEEECCCEEEEEECCCCCCCCCHHHHEEE
DREGNVIEGHMKVTSEIKMHLAVYNMREDVKAIVHAHPPASTAFSVSKEKLDDPVILPEA
CCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHCCCCEECHHH
VFSLGKIGYCEYGTPSTDEVPKAIEKEIPYSDVLLLSNHGALTVGTDVMQAYYRMENLEM
HHHHCCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEECHHHHHHHHHHHHHHH
VSKVTIYSKMIGNIKTLNELQVEKLNKVKEEKGWG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNETYLRLQIVEVGKRLQQRFFVASNDGNISAKLDENTILITPTGVNKGEVTPDQIIKV
CCCCEEEEEEHHHHHHHHHHHEEEECCCCCEEEEECCCEEEEEECCCCCCCCCHHHHEEE
DREGNVIEGHMKVTSEIKMHLAVYNMREDVKAIVHAHPPASTAFSVSKEKLDDPVILPEA
CCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHCCCCEECHHH
VFSLGKIGYCEYGTPSTDEVPKAIEKEIPYSDVLLLSNHGALTVGTDVMQAYYRMENLEM
HHHHCCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEECHHHHHHHHHHHHHHH
VSKVTIYSKMIGNIKTLNELQVEKLNKVKEEKGWG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA