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The map label for this gene is sdhA [H]

Identifier: 148379197

GI number: 148379197

Start: 1337653

End: 1338543

Strand: Direct

Name: sdhA [H]

Synonym: CBO1215

Alternate gene names: 148379197

Gene position: 1337653-1338543 (Clockwise)

Preceding gene: 148379196

Following gene: 148379198

Centisome position: 34.41

GC content: 37.37

Gene sequence:

>891_bases
ATGTTCGTAAACACAGGAAAAGAACTTATAAGAGTATGTGATGAAAAAAAATTAAAAATATGGGAATATACTTTAAAAAT
AGAAGCAGAAAGTAAGAATGTAAGTGAAAAAGAAGTATTTGAAACTATGAGAAAAGCTCTTAAGGTTATGCAACATTCAG
CAGAAATAGGAAGAGAAAAAGAAGTTAAATCTGTAAGTGGATTAATAGGTGGAGATGCTTTAAAGTTAGAAAAATATTCC
AAGGGGGAAAATACACTAACAGGAAATTTCATGGTAAGGGCTATGGCTATGGCTATTTCAACTTCTGAAGTTAATGCAGC
TATGGGAAGAATCGTAGCATCACCAACAGCAGGATCAGCAGGAATATTGCCAGCTGTAGTAATAGCTGCAGGAGAAAAAT
TAAATAAAAGTGAAGATGATTTAGTTAAGGCTTTATTTACAGCCTCTGGATTAGGAATACTTATTTCTAAAAATGCTACA
ACAGCAGGAGCGGAAGGTGGATGTCAAGCAGAATGTGGTTCAGCCGCAGCAATGGCATCTGCAGCAGTAGTAGAAATGAT
GGGAGGAAGCGTAGAACAAGCTTTAGATGCAGGAGCTATAGTTATAAAAAACATACTAGGGCTTGTTTGTGATCCAGTGG
CAGGACTTGTAGAAATACCTTGTGCGAAAAGAAATATTGCAGGGACAGTAAGTGCTTTAACTACAGCAGACATGGTAATG
GCAGGAGTTACAAGTCATATTCCTTTCGATGATTCGGTAGAGGCAATGTATAGAGTTGGAAAACAACTTCCATCTTGTCT
TAGAGAAACAGCTTTAGGTGGGGTGGCTGTTACTGAGGCAGGGCTAAAGCTTAAAGAAAAAGTATTCGGATGCACAGGTT
GTAAAAAATAG

Upstream 100 bases:

>100_bases
AGATGGAGAAATACCAAAGAAAATAATAGATGAAATAAAAGCTATTAAGGATATAGAGAATGTAAAAATCATAAATCCAA
TAAAATAGGAGGAAAAATTA

Downstream 100 bases:

>100_bases
ATATAAGTAACATAATATAAAAAATGAAAAAGCTATGAAATATAGGATTAATACCTTAATTTCATAGCTTTTATTTGTTT
ATAGTATTTATTTGTATTTA

Product: L-serine dehydratase, iron-sulfur-dependent, alpha subunit

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MFVNTGKELIRVCDEKKLKIWEYTLKIEAESKNVSEKEVFETMRKALKVMQHSAEIGREKEVKSVSGLIGGDALKLEKYS
KGENTLTGNFMVRAMAMAISTSEVNAAMGRIVASPTAGSAGILPAVVIAAGEKLNKSEDDLVKALFTASGLGILISKNAT
TAGAEGGCQAECGSAAAMASAAVVEMMGGSVEQALDAGAIVIKNILGLVCDPVAGLVEIPCAKRNIAGTVSALTTADMVM
AGVTSHIPFDDSVEAMYRVGKQLPSCLRETALGGVAVTEAGLKLKEKVFGCTGCKK

Sequences:

>Translated_296_residues
MFVNTGKELIRVCDEKKLKIWEYTLKIEAESKNVSEKEVFETMRKALKVMQHSAEIGREKEVKSVSGLIGGDALKLEKYS
KGENTLTGNFMVRAMAMAISTSEVNAAMGRIVASPTAGSAGILPAVVIAAGEKLNKSEDDLVKALFTASGLGILISKNAT
TAGAEGGCQAECGSAAAMASAAVVEMMGGSVEQALDAGAIVIKNILGLVCDPVAGLVEIPCAKRNIAGTVSALTTADMVM
AGVTSHIPFDDSVEAMYRVGKQLPSCLRETALGGVAVTEAGLKLKEKVFGCTGCKK
>Mature_296_residues
MFVNTGKELIRVCDEKKLKIWEYTLKIEAESKNVSEKEVFETMRKALKVMQHSAEIGREKEVKSVSGLIGGDALKLEKYS
KGENTLTGNFMVRAMAMAISTSEVNAAMGRIVASPTAGSAGILPAVVIAAGEKLNKSEDDLVKALFTASGLGILISKNAT
TAGAEGGCQAECGSAAAMASAAVVEMMGGSVEQALDAGAIVIKNILGLVCDPVAGLVEIPCAKRNIAGTVSALTTADMVM
AGVTSHIPFDDSVEAMYRVGKQLPSCLRETALGGVAVTEAGLKLKEKVFGCTGCKK

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=286, Percent_Identity=33.9160839160839, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1788116, Length=283, Percent_Identity=33.9222614840989, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1789161, Length=184, Percent_Identity=40.2173913043478, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 30780; Mature: 30780

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVNTGKELIRVCDEKKLKIWEYTLKIEAESKNVSEKEVFETMRKALKVMQHSAEIGREK
CCCCCHHHHHHHHCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
EVKSVSGLIGGDALKLEKYSKGENTLTGNFMVRAMAMAISTSEVNAAMGRIVASPTAGSA
HHHHHHHHHCCCCEEEHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GILPAVVIAAGEKLNKSEDDLVKALFTASGLGILISKNATTAGAEGGCQAECGSAAAMAS
CHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHH
AAVVEMMGGSVEQALDAGAIVIKNILGLVCDPVAGLVEIPCAKRNIAGTVSALTTADMVM
HHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AGVTSHIPFDDSVEAMYRVGKQLPSCLRETALGGVAVTEAGLKLKEKVFGCTGCKK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFVNTGKELIRVCDEKKLKIWEYTLKIEAESKNVSEKEVFETMRKALKVMQHSAEIGREK
CCCCCHHHHHHHHCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
EVKSVSGLIGGDALKLEKYSKGENTLTGNFMVRAMAMAISTSEVNAAMGRIVASPTAGSA
HHHHHHHHHCCCCEEEHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GILPAVVIAAGEKLNKSEDDLVKALFTASGLGILISKNATTAGAEGGCQAECGSAAAMAS
CHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHH
AAVVEMMGGSVEQALDAGAIVIKNILGLVCDPVAGLVEIPCAKRNIAGTVSALTTADMVM
HHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AGVTSHIPFDDSVEAMYRVGKQLPSCLRETALGGVAVTEAGLKLKEKVFGCTGCKK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]